 Ketoglutaric Acids
"Ketoglutaric Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
| Descriptor ID |
D007656
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| MeSH Number(s) |
D02.241.081.337.351.502 D02.241.755.465
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ketoglutaric Acids".
Below are MeSH descriptors whose meaning is more specific than "Ketoglutaric Acids".
This graph shows the total number of publications written about "Ketoglutaric Acids" by people in this website by year, and whether "Ketoglutaric Acids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ketoglutaric Acids" by people in Profiles.
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Seo H, Kramer AC, McLendon BA, Cain JW, Burghardt RC, Wu G, Bazer FW, Johnson GA. Elongating porcine conceptuses can utilize glutaminolysis as an anaplerotic pathway to maintain the TCA cycle?. Biol Reprod. 2022 09 12; 107(3):823-833.
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Hamby H, Li B, Shinopoulos KE, Keller HR, Elliott SJ, Dukovic G. Light-driven carbon-carbon bond formation via CO2 reduction catalyzed by complexes of CdS nanorods and a 2-oxoacid oxidoreductase. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):135-140.
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Pollyea DA, Stevens BM, Jones CL, Winters A, Pei S, Minhajuddin M, D'Alessandro A, Culp-Hill R, Riemondy KA, Gillen AE, Hesselberth JR, Abbott D, Schatz D, Gutman JA, Purev E, Smith C, Jordan CT. Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia. Nat Med. 2018 12; 24(12):1859-1866.
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Mitchell BL, Bhandari RK, Bebarta VS, Rockwood GA, Boss GR, Logue BA. Toxicokinetic profiles of a-ketoglutarate cyanohydrin, a cyanide detoxification product, following exposure to potassium cyanide. Toxicol Lett. 2013 Sep 12; 222(1):83-9.
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Vohwinkel CU, Lecuona E, Sun H, Sommer N, Vad?sz I, Chandel NS, Sznajder JI. Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. J Biol Chem. 2011 Oct 28; 286(43):37067-76.
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Rudolph J, Kim J, Copley SD. Multiple turnovers of the nicotino-enzyme PdxB require a-keto acids as cosubstrates. Biochemistry. 2010 Nov 02; 49(43):9249-55.
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Villalobos AR, Dunnick CA, Pritchard JB. Mechanism mediating basolateral transport of 2,4-dichlorophenoxyacetic acid in rat kidney. J Pharmacol Exp Ther. 1996 Aug; 278(2):582-9.
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