 Intercellular Signaling Peptides and Proteins
"Intercellular Signaling Peptides and Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
| Descriptor ID |
D036341
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| MeSH Number(s) |
D12.644.276 D12.776.467 D23.529
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Intercellular Signaling Peptides and Proteins".
Below are MeSH descriptors whose meaning is more specific than "Intercellular Signaling Peptides and Proteins".
This graph shows the total number of publications written about "Intercellular Signaling Peptides and Proteins" by people in this website by year, and whether "Intercellular Signaling Peptides and Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 0 | 4 | | 1997 | 4 | 1 | 5 | | 1998 | 3 | 2 | 5 | | 1999 | 3 | 5 | 8 | | 2000 | 0 | 5 | 5 | | 2001 | 3 | 9 | 12 | | 2002 | 8 | 9 | 17 | | 2003 | 4 | 15 | 19 | | 2004 | 7 | 7 | 14 | | 2005 | 11 | 6 | 17 | | 2006 | 4 | 13 | 17 | | 2007 | 7 | 12 | 19 | | 2008 | 7 | 7 | 14 | | 2009 | 7 | 12 | 19 | | 2010 | 6 | 4 | 10 | | 2011 | 5 | 3 | 8 | | 2012 | 5 | 4 | 9 | | 2013 | 7 | 11 | 18 | | 2014 | 3 | 10 | 13 | | 2015 | 3 | 7 | 10 | | 2016 | 4 | 4 | 8 | | 2017 | 2 | 6 | 8 | | 2018 | 3 | 5 | 8 | | 2019 | 2 | 1 | 3 | | 2020 | 3 | 4 | 7 | | 2021 | 2 | 4 | 6 | | 2022 | 0 | 2 | 2 | | 2023 | 1 | 3 | 4 | | 2024 | 1 | 3 | 4 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Intercellular Signaling Peptides and Proteins" by people in Profiles.
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Yue J, LeSon CE, Rimland CA, Brodeur K, Weng R, Hsu EE, Lam MT, Meyer M, Okada S, Hsu ALD, Alhezam MA, Perron MM, Halyabar O, Dedeoglu F, Nigrovic PA, Shimamura A, Rowe RG, Cooper MA, Vogel TP, Gillispie-Taylor M, Peterson R, Lin C, Nowicki KD, Dollerschell K, Nakano TA, Labrosse R, Cochino AV, Ioan A, Mendonca LO, Barros SF, Kalil J, Perez-Rojas J, Diaz-Kuan A, Sobel ES, Moussa T, Lee SSM, Koh LW, Khan A, Sutnga S, Khubchandani R, Shoman W, El Chazli Y, Pinto B, Kavadichanda C, Abraham RS, Sun X, Zhou Q, Naidu G, Sharma A, Esperanzate C, Kastner DL, Aksentijevich I, Kelly SJ, Hershfield M, Tarrant TK, Lee PY. Diagnostic Implications and Correlates of Plasma Adenosine Deaminase 2 Activity and ADA2 Variants. Arthritis Rheumatol. 2026 Mar; 78(3):734-742.
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Sun NY, Kumar S, Kim YS, Varghese D, Mendoza A, Nguyen R, Okada R, Reilly K, Widemann B, Pommier Y, Elloumi F, Dhall A, Taniyama D, Patel M, Aber E, Contreras CF, Kaplan RN, Kiseljak-Vassiliades K, Wierman ME, Martinez D, Pogoriler J, Hamilton AK, Diskin SJ, Maris JM, Robey RW, Gottesman MM, Del Rivero J, Roper N. Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma. Nat Commun. 2025 Jul 01; 16(1):5511.
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Rodrigues Sousa E, de Brot S, Zoni E, Zeinali S, Brunello A, Scarpa M, De Menna M, La Manna F, Abey Alexander A, Klima I, Freeman DW, Gates BL, Cristaldi DA, Guenat OT, Kruithof BPT, Spike BT, Chouvardas P, Kruithof-de Julio M. CRIPTO's multifaceted role in driving aggressive prostate cancer unveiled by in vivo, organoid, and patient data. Oncogene. 2025 Mar; 44(7):462-475.
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Abe-Ridgway K, Puente MA. Bilateral cataracts in a three-year-old with deficiency of adenosine deaminase 2 (DADA2), hyperferritinemia, and prolonged steroid use. Ophthalmic Genet. 2025 Feb; 46(1):74-78.
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Burgy O, Mayr CH, Schenesse D, Fousekis Papakonstantinou E, Ballester B, Sengupta A, She Y, Hu Q, Melo-Narvaéz MC, Jain E, Pestoni JC, Mozurak M, Estrada-Bernal A, Onwuka U, Coughlan C, Parimon T, Chen P, Heimerl T, Bange G, Schmeck BT, Lindner M, Hilgendorff A, Ruppert C, Güenther A, Mann M, Yildirim AÖ, Eickelberg O, Jung AL, Schiller HB, Lehmann M, Burgstaller G, Königshoff M. Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis. JCI Insight. 2024 Aug 15; 9(18).
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Swift IJ, Rademakers R, Finch N, Baker M, Ghidoni R, Benussi L, Binetti G, Rossi G, Synofzik M, Wilke C, Mengel D, Graff C, Takada LT, Sánchez-Valle R, Antonell A, Galimberti D, Fenoglio C, Serpente M, Arcaro M, Schreiber S, Vielhaber S, Arndt P, Santana I, Almeida MR, Moreno F, Barandiaran M, Gabilondo A, Stubert J, Gómez-Tortosa E, Agüero P, Sainz MJ, Gohda T, Murakoshi M, Kamei N, Kittel-Schneider S, Reif A, Weigl J, Jian J, Liu C, Serrero G, Greither T, Theil G, Lohmann E, Gazzina S, Bagnoli S, Coppola G, Bruni A, Quante M, Kiess W, Hiemisch A, Jurkutat A, Block MS, Carlson AM, Bråthen G, Sando SB, Grøntvedt GR, Lauridsen C, Heslegrave A, Heller C, Abel E, Gómez-Núñez A, Puey R, Arighi A, Rotondo E, Jiskoot LC, Meeter LHH, Durães J, Lima M, Tábuas-Pereira M, Lemos J, Boeve B, Petersen RC, Dickson DW, Graff-Radford NR, LeBer I, Sellami L, Lamari F, Clot F, Borroni B, Cantoni V, Rivolta J, Lleó A, Fortea J, Alcolea D, Illán-Gala I, Andres-Cerezo L, Van Damme P, Clarimon J, Steinacker P, Feneberg E, Otto M, van der Ende EL, van Swieten JC, Seelaar H, Zetterberg H, Sogorb-Esteve A, Rohrer JD. A systematic review of progranulin concentrations in biofluids in over 7,000 people-assessing the pathogenicity of GRN mutations and other influencing factors. Alzheimers Res Ther. 2024 03 28; 16(1):66.
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Dinarello A, May M, Amo-Aparicio J, Azam T, Gaballa JM, Marchetti C, Tesoriere A, Ghirardo R, Redzic JS, Webber WS, Atif SM, Li S, Eisenmesser EZ, de Graaf DM, Dinarello CA. IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1ß secretion. Proc Natl Acad Sci U S A. 2023 11 07; 120(45):e2306476120.
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Hu CJ, Laux A, Gandjeva A, Wang L, Li M, Brown RD, Riddle S, Kheyfets VO, Tuder RM, Zhang H, Stenmark KR. The Effect of Hypoxia-inducible Factor Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2023 07; 69(1):73-86.
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Lee PY, Davidson BA, Abraham RS, Alter B, Arostegui JI, Bell K, Belot A, Bergerson JRE, Bernard TJ, Brogan PA, Berkun Y, Deuitch NT, Dimitrova D, Georgin-Lavialle SA, Gattorno M, Grimbacher B, Hashem H, Hershfield MS, Ichord RN, Izawa K, Kanakry JA, Khubchandani RP, Klouwer FCC, Luton EA, Man AW, Meyts I, Van Montfrans JM, Ozen S, Saarela J, Santo GC, Sharma A, Soldatos A, Sparks R, Torgerson TR, Uriarte IL, Youngstein TAB, Zhou Q, Aksentijevich I, Kastner DL, Chambers EP, Ombrello AK. Evaluation and Management of Deficiency of Adenosine Deaminase 2: An International Consensus Statement. JAMA Netw Open. 2023 05 01; 6(5):e2315894.
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Ameen SS, Griem-Krey N, Dufour A, Hossain MI, Hoque A, Sturgeon S, Nandurkar H, Draxler DF, Medcalf RL, Kamaruddin MA, Lucet IS, Leeming MG, Liu D, Dhillon A, Lim JP, Basheer F, Zhu HJ, Bokhari L, Roulston CL, Paradkar PN, Kleifeld O, Clarkson AN, Wellendorph P, Ciccotosto GD, Williamson NA, Ang CS, Cheng HC. N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection. Mol Cell Proteomics. 2023 05; 22(5):100543.
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