 Diabetes Mellitus, Type 1
"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Descriptor ID |
D003922
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| MeSH Number(s) |
C18.452.394.750.124 C19.246.267 C20.111.327
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| Concept/Terms |
Diabetes Mellitus, Type 1- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Brittle
- Brittle Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent
- Diabetes Mellitus, Insulin Dependent
- Insulin-Dependent Diabetes Mellitus
- Diabetes Mellitus, Juvenile-Onset
- Diabetes Mellitus, Juvenile Onset
- Juvenile-Onset Diabetes Mellitus
- Diabetes Mellitus, Ketosis-Prone
- Diabetes Mellitus, Ketosis Prone
- Ketosis-Prone Diabetes Mellitus
- Juvenile-Onset Diabetes
- Diabetes, Juvenile-Onset
- Juvenile Onset Diabetes
- Diabetes Mellitus, Type I
- Diabetes Mellitus, Sudden-Onset
- Diabetes Mellitus, Sudden Onset
- Mellitus, Sudden-Onset Diabetes
- Sudden-Onset Diabetes Mellitus
- Type 1 Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent, 1
- Insulin-Dependent Diabetes Mellitus 1
- Insulin Dependent Diabetes Mellitus 1
- Type 1 Diabetes
- Diabetes, Type 1
- IDDM
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Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".
Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".
This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in this website by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 10 | 2 | 12 | | 1997 | 4 | 4 | 8 | | 1998 | 8 | 2 | 10 | | 1999 | 17 | 2 | 19 | | 2000 | 12 | 5 | 17 | | 2001 | 9 | 2 | 11 | | 2002 | 17 | 2 | 19 | | 2003 | 22 | 3 | 25 | | 2004 | 42 | 5 | 47 | | 2005 | 34 | 2 | 36 | | 2006 | 25 | 6 | 31 | | 2007 | 36 | 3 | 39 | | 2008 | 40 | 9 | 49 | | 2009 | 62 | 8 | 70 | | 2010 | 51 | 6 | 57 | | 2011 | 63 | 4 | 67 | | 2012 | 56 | 7 | 63 | | 2013 | 80 | 6 | 86 | | 2014 | 81 | 6 | 87 | | 2015 | 84 | 3 | 87 | | 2016 | 66 | 4 | 70 | | 2017 | 94 | 9 | 103 | | 2018 | 109 | 8 | 117 | | 2019 | 119 | 6 | 125 | | 2020 | 130 | 8 | 138 | | 2021 | 114 | 4 | 118 | | 2022 | 136 | 3 | 139 | | 2023 | 113 | 2 | 115 | | 2024 | 106 | 6 | 112 | | 2025 | 91 | 5 | 96 | | 2026 | 25 | 0 | 25 |
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Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles.
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Bluestone JA, Herold KC, Sussel L. Type 1 Diabetes: Advances in Understanding and Treatment 100 Years after the Discovery of Insulin. Cold Spring Harb Perspect Med. 2026 May 01; 16(5).
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Karakus KE, Akturk HK, Kruger D, Ahmann A, Bharvaga A, Langel CR, Ackeifi CA, Rosen J, Pyle L, Snell-Bergeon JK, Shah VN. Effect of Semaglutide on Insulin Dose Reduction in Adults With Type 1 Diabetes and Obesity Using Automated Insulin Delivery Systems: ADJUST-T1D Post Hoc Analysis. Diabetes Care. 2026 May 01; 49(5):718-723.
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Carry PM, Kim S, Zwick NL, Buckner T, DeFelice B, Johnson RK, Seifert J, Waugh K, Dong F, Vanderlinden LA, Frohnert BI, Kechris K, Fiehn O, Rewers M, Norris JM. Increased Levels of the Vitamin D Metabolite Ratio Are Protective Against Progression From Islet Autoimmunity to T1D. J Clin Endocrinol Metab. 2026 Apr 22; 111(5):1438-1449.
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Denson AM, Rodriguez KE, Letourneau-Freiberg LR, Kandasamy B, Naylor RN, Abdullatif HD, Benjamin RW, Cobry E, Freemark MS, Thomas IH, Greeley SAW. Children With Pancreatic Hypoplasia Experience Poor Weight Gain and Labile Diabetes but Low Incidence of DKA. J Clin Endocrinol Metab. 2026 Mar 17; 111(4):e1164-e1173.
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Chen NC, Shah VN, McQueen RB. Time in Range and Incident Diabetic Retinopathy: Clinical and Economic Evidence From Real-World Type 1 Diabetes Care. J Clin Endocrinol Metab. 2026 Mar 17; 111(4):e1146-e1152.
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Akturk HK, Karakus KE, Chen B, Walker TC. Exploring the Relationship Between Newly Defined Continuous Glucose Monitoring (CGM) Metrics and the Standard CGM Metrics in 30,000 People with Type 1 Diabetes. Diabetes Technol Ther. 2026 Mar; 28(3):264-270.
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Moscoso-Vasquez M, Ekhlaspour L, Brown SA, DeBoer MD, Berget C, Cobry EC, Wadwa RP, Capodanno G, Cengiz E, Wong JC, Pryor EC, Villa-Tamayo MF, El Fathi A, Holmes V, Davis Prince S, Escobar E, Towers L, Hosseininpour Y, Narayan A, Koravi CLK, Nguyen T, Fulkerson D, Barnett CL, Oliveri MC, Breton MD, Forlenza GP. Safety and Feasibility of a Fully Automated Insulin Delivery System: FCL@Home, a Multicenter Randomized Clinical Trial in Individuals With Type 1 Diabetes. Diabetes Care. 2026 Mar 01; 49(3):401-409.
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Jia X, Zhang C, Waugh K, Miao D, Michels AW, Rewers MJ, Yu L. Identifying Insulin Autoantibodies With Differential Risk in Type 1 Diabetes With a Novel Bridging ELISA. Diabetes. 2026 Mar 01; 75(3):519-525.
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Montaser E, Williams C, Shah VN. Assessing Time Below Range as a Predictor of Severe Hypoglycemia: Insights From Six Clinical Trials. Diabetes Care. 2026 Mar 01; 49(3):483-489.
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Greenbaum CJ, Long SA, Gitelman SE, Gaglia JL, Daniels M, Brusko TM, Lord S, Bundy BN, Krischer JP, Haller MJ, Steck AK, DiMeglio LA, Evans-Molina C, Moran A, Prahalad P, Wilson DM, Russell WE, Sherr JL, Raskin P, Clements MA, Moore WV, Libman I, Wassermann K, von Herrath M, Bergholdt R, Hastrup H, Kobernat SE, Kus AM, Tung LW, Goland RS, Herold KC. Phase I Clinical Trial of Islet Antigen-Specific Plasmid Coexpressing Tolerogenic Proteins Demonstrates Safety in Adults With Type 1 Diabetes. Diabetes. 2026 Mar 01; 75(3):506-518.
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