 Diabetes Mellitus, Type 1
"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Descriptor ID |
D003922
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| MeSH Number(s) |
C18.452.394.750.124 C19.246.267 C20.111.327
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| Concept/Terms |
Diabetes Mellitus, Type 1- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Brittle
- Brittle Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent
- Diabetes Mellitus, Insulin Dependent
- Insulin-Dependent Diabetes Mellitus
- Diabetes Mellitus, Juvenile-Onset
- Diabetes Mellitus, Juvenile Onset
- Juvenile-Onset Diabetes Mellitus
- Diabetes Mellitus, Ketosis-Prone
- Diabetes Mellitus, Ketosis Prone
- Ketosis-Prone Diabetes Mellitus
- Juvenile-Onset Diabetes
- Diabetes, Juvenile-Onset
- Juvenile Onset Diabetes
- Diabetes Mellitus, Type I
- Diabetes Mellitus, Sudden-Onset
- Diabetes Mellitus, Sudden Onset
- Mellitus, Sudden-Onset Diabetes
- Sudden-Onset Diabetes Mellitus
- Type 1 Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent, 1
- Insulin-Dependent Diabetes Mellitus 1
- Insulin Dependent Diabetes Mellitus 1
- Type 1 Diabetes
- Diabetes, Type 1
- IDDM
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Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".
Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".
This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in this website by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 10 | 2 | 12 | | 1997 | 4 | 4 | 8 | | 1998 | 7 | 2 | 9 | | 1999 | 16 | 2 | 18 | | 2000 | 12 | 5 | 17 | | 2001 | 8 | 2 | 10 | | 2002 | 17 | 2 | 19 | | 2003 | 22 | 3 | 25 | | 2004 | 42 | 5 | 47 | | 2005 | 34 | 2 | 36 | | 2006 | 26 | 6 | 32 | | 2007 | 35 | 2 | 37 | | 2008 | 40 | 9 | 49 | | 2009 | 59 | 8 | 67 | | 2010 | 50 | 8 | 58 | | 2011 | 63 | 4 | 67 | | 2012 | 56 | 7 | 63 | | 2013 | 80 | 7 | 87 | | 2014 | 81 | 6 | 87 | | 2015 | 83 | 4 | 87 | | 2016 | 66 | 4 | 70 | | 2017 | 94 | 9 | 103 | | 2018 | 109 | 8 | 117 | | 2019 | 119 | 6 | 125 | | 2020 | 131 | 8 | 139 | | 2021 | 115 | 4 | 119 | | 2022 | 136 | 3 | 139 | | 2023 | 110 | 2 | 112 | | 2024 | 103 | 6 | 109 | | 2025 | 96 | 4 | 100 | | 2026 | 60 | 0 | 60 |
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Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles.
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Jones Iv AR, Smith PS, Dooms H. Cell-intrinsic IL-7Ra deficiency in Foxp3+ Tregs increases type 1 diabetes incidence in NOD mice. Immunohorizons. 2026 Aug 04; 10(8).
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Jacobsen LM, Cuthbertson D, Felton J, Sherr JL, Simmons KM, Hosford J, Ismail HM, Greenbaum CJ, Wherrett DK, Pinckney A, Sanda S, DiMeglio LA, Higdon LE, Evans-Molina C. Extended Follow-up of Type 1 Diabetes Immunotherapy Trial Participants Suggests Benign Side Effect Profile. Diabetes Care. 2026 Aug 01; 49(8):1428-1433.
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Haskins K, Delong T, DiLisio JE, Baker RL. Hybrid Insulin Peptides as Antigens and Tolerogens for Pathogenic T Cells in Autoimmune Diabetes. Immunol Rev. 2026 Aug; 341(1):e70142.
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Bjornstad P, Choi YJ, Narongkiatikhun P, Karihaloo A, Prasad PV, Li LP, Tommerdahl KL, Sethi M, Ramesh S, Birznieks C, Clarke A, Elia Y, Curtis J, Clarson C, Weissenkampen D, D'Antonio M, Pinzon Cortes JA, Hampson H, Yuan L, van Eeghen SA, Kanter JE, Bornfeldt KE, Vaisar T, Ladd P, Heerspink HJL, de Boer IH, Goodrich JA, Street K, Tuttle KR, Bergmann KR, Smith C, Hodgin JB, Schaub JA, Nair V, Menon R, Naik AS, McCown PJ, AlAkwaa F, Eddy S, Otto E, Kim NH, Nelson RG, Puelles VG, van Raalte DH, Cherney DZI, Pyle L, Mahmud FH, Kretzler M. SGLT2 inhibition modulates metabolic, vascular, and inflammatory molecular markers in the kidney in youth with type 1 diabetes. Sci Transl Med. 2026 Jul 22; 18(859):eaee1005.
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Pauley ME, Coughlan C, Dong F, Bucca B, Tanner B, Chartier-Logan C, Shapiro ALB, Snell-Bergeon JK. Type 1 diabetes is associated with higher plasma levels of biomarkers of neurodegeneration and neuroinflammation. Front Immunol. 2026; 17:1860993.
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Melin J, Tamura R, O'Donnell H, Johnson SB. Child and mother study satisfaction in a longitudinal study of children at-risk for type 1 diabetes. BMC Pediatr. 2026 Jul 02; 26(1).
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Karakus KE, Clayton MG, Baschal EE, McDaniel KA, Yu L, Haider Z, Polsky S, Akturk HK, Gottlieb PA, Garg SK, Michels AW. Differences in Clinical Manifestations and Islet Autoantibodies by Age in Adult-Onset Type 1 Diabetes. Diabetes Care. 2026 07 01; 49(7):1194-1201.
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Weber D, Modeste J, Peeling S, Foster TP, Bruggeman BS, Jacobsen LM, Schatz DA, Haller MJ. Low-Dose Antithymocyte Globulin in Type 1 Diabetes: Real-World Exploratory Observation of C-Peptide by Modified Quantitative Response (mQR). Diabetes Care. 2026 07 01; 49(7):1258-1261.
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Hakola L, Clasen JL, Uusitalo U, Andrén Aronsson C, Hummel S, Mattila M, Niinistö S, Toppari J, Ziegler AG, Hagopian WA, Akolkar B, Rewers MJ, McIndoe RA, Lernmark Å, Krischer JP, Norris JM, Erlund I, Virtanen SM. Retinol, Carotenoid, and Tocopherol Intake and Status, and the Risk of Islet Autoimmunity and Type 1 Diabetes: The Environmental Determinants of Diabetes in the Young Study. Diabetes Metab Res Rev. 2026 Jul; 42(5):e70196.
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Pinzon Cortes JA, Narongkiatikhun P, Snethlage CF, Del Castillo D, Tommerdahl KL, Nadeau KJ, Bjornstad P. Beyond Glycemia in T1D: Insulin Resistance and Multiorgan Injury in Type 1 Diabetes-Part 2. Endocrinol Metab Clin North Am. 2026 Sep; 55(3):407-419.
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