 Diabetes Mellitus, Type 1
"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Descriptor ID |
D003922
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| MeSH Number(s) |
C18.452.394.750.124 C19.246.267 C20.111.327
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| Concept/Terms |
Diabetes Mellitus, Type 1- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Brittle
- Brittle Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent
- Diabetes Mellitus, Insulin Dependent
- Insulin-Dependent Diabetes Mellitus
- Diabetes Mellitus, Juvenile-Onset
- Diabetes Mellitus, Juvenile Onset
- Juvenile-Onset Diabetes Mellitus
- Diabetes Mellitus, Ketosis-Prone
- Diabetes Mellitus, Ketosis Prone
- Ketosis-Prone Diabetes Mellitus
- Juvenile-Onset Diabetes
- Diabetes, Juvenile-Onset
- Juvenile Onset Diabetes
- Diabetes Mellitus, Type I
- Diabetes Mellitus, Sudden-Onset
- Diabetes Mellitus, Sudden Onset
- Mellitus, Sudden-Onset Diabetes
- Sudden-Onset Diabetes Mellitus
- Type 1 Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent, 1
- Insulin-Dependent Diabetes Mellitus 1
- Insulin Dependent Diabetes Mellitus 1
- Type 1 Diabetes
- Diabetes, Type 1
- IDDM
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Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".
Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".
This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in this website by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 10 | 2 | 12 | | 1997 | 4 | 4 | 8 | | 1998 | 7 | 2 | 9 | | 1999 | 16 | 2 | 18 | | 2000 | 12 | 5 | 17 | | 2001 | 8 | 2 | 10 | | 2002 | 17 | 2 | 19 | | 2003 | 22 | 3 | 25 | | 2004 | 42 | 5 | 47 | | 2005 | 34 | 2 | 36 | | 2006 | 26 | 6 | 32 | | 2007 | 35 | 2 | 37 | | 2008 | 40 | 9 | 49 | | 2009 | 59 | 8 | 67 | | 2010 | 50 | 8 | 58 | | 2011 | 63 | 4 | 67 | | 2012 | 56 | 7 | 63 | | 2013 | 81 | 7 | 88 | | 2014 | 81 | 6 | 87 | | 2015 | 84 | 4 | 88 | | 2016 | 66 | 4 | 70 | | 2017 | 94 | 10 | 104 | | 2018 | 110 | 9 | 119 | | 2019 | 120 | 6 | 126 | | 2020 | 132 | 9 | 141 | | 2021 | 115 | 4 | 119 | | 2022 | 136 | 3 | 139 | | 2023 | 111 | 2 | 113 | | 2024 | 106 | 7 | 113 | | 2025 | 99 | 4 | 103 | | 2026 | 76 | 0 | 76 |
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Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles.
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Douglas K, Delong T. Hybrid Insulin Peptides in Type 1 Diabetes: How They Form and Why They Matter. Immunol Rev. 2026 Oct; 343(1):e70185.
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Mattila M, Mramba LK, Niinistö S, Erlund I, Liu X, Uusitalo U, Andrén Aronsson C, Hummel S, Frohnert BI, Parikh HM, Rich SS, Hagopian W, Toppari J, Lernmark Å, Ziegler AG, Rewers M, Krischer JP, Hakola L, Norris JM, Virtanen SM. Dietary vitamin C intake and the risk of islet autoimmunity and type 1 diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Eur J Nutr. 2026 Sep 24; 65(7).
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Herold KC, Dayan CM, Chatenoud L, Gitelman SE, Sumnik Z, Simmons K, Szypowska A, Knecht LA, Niemoeller E, Rigby MR, Tian W, Hill R, Ramos EL. Preserving beta cell function in children and adolescents with newly diagnosed stage 3 type 1 diabetes: per-protocol population analysis from the PROTECT randomised trial. Diabetologia. 2026 Dec; 69(12):3501-3511.
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Ziegler AG, Rewers MJ, Achenbach P, Bell KJ, Bonifacio E, DiMeglio LA, Dutta S, Elding Larsson H, Frohnert BI, Griffin KJ, Hagopian WA, Jacobsen LM, Lange K, Mallone R, Narendran P, Oron T, Rich SS, McDonough CW, ?migoc Schweiger D, ?umník Z, Szypowska A, Veijola R, Vercauteren J, Wentworth JM, Wherrett DK, Albanese-O'Neill A. International consensus guidance for general population screening for islet autoantibodies to diagnose early-stage type 1 diabetes: a nominal group technique process. Diabetologia. 2026 Dec; 69(12):3370-3395.
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Hohsfield KR, Dong F, Waugh K, Steck AK, Buckner T, Johnson RK, Carry PM, Frohnert B, Rewers M, Norris JM. A Secular Increase in the Incidence of Islet Autoimmunity Among Colorado Children With Moderate-Risk HLA Genotypes. Diabetes Care. 2026 Sep 01; 49(9):1700-1704.
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Hanna SJ, Robinson EJ, Thayer TC, Nakayama M, Landry L, Andrews R, Dolton G, Davies J, Williams E, Pearson JA, Sewell AK, Narendran P, Wraith DC, Howell A, Young P, Hart M, Lindqvist A, Wong FS, Tree TI, Dayan CM, Tatovic D. Tracking GAD-specific T cell expansions in type 1 diabetes by intradermal GAD-alum challenge. JCI Insight. 2026 Oct 22; 11(20).
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Montaser E, Bhasin K, Kruger D, Akturk HK, Ahmann A, Snell-Bergeon JK, Shah VN. Glycaemic Changes After Semaglutide Discontinuation in Adults With Type 1 Diabetes Using Automated Insulin Delivery: Analysis of the ADJUST-T1D Extension Study. Diabetes Obes Metab. 2026 Nov; 28(11):10736-10742.
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Clasen JL, Jonsdottir B, Vehik K, Lynch KF, Parikh HM, Koskenniemi JJ, Lernmark Å, Agardh D, Hagopian WA, Rewers MJ, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Haller M, Elding Larsson H. Thyroid autoimmunity and the subsequent development of islet and celiac autoimmunity in the TEDDY study. Am J Epidemiol. 2026 08 05; 195(8):2111-2120.
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Jones Iv AR, Smith PS, Dooms H. Cell-intrinsic IL-7Ra deficiency in Foxp3+ Tregs increases type 1 diabetes incidence in NOD mice. Immunohorizons. 2026 Aug 04; 10(8).
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Jacobsen LM, Cuthbertson D, Felton J, Sherr JL, Simmons KM, Hosford J, Ismail HM, Greenbaum CJ, Wherrett DK, Pinckney A, Sanda S, DiMeglio LA, Higdon LE, Evans-Molina C. Extended Follow-up of Type 1 Diabetes Immunotherapy Trial Participants Suggests Benign Side Effect Profile. Diabetes Care. 2026 Aug 01; 49(8):1428-1433.
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