 Carcinogenesis
"Carcinogenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Descriptor ID |
D063646
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| MeSH Number(s) |
C04.697.098 C23.550.727.098
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| Concept/Terms |
Carcinogenesis- Carcinogenesis
- Carcinogeneses
- Tumorigenesis
- Tumorigeneses
- Oncogenesis
- Oncogeneses
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Below are MeSH descriptors whose meaning is more general than "Carcinogenesis".
Below are MeSH descriptors whose meaning is more specific than "Carcinogenesis".
This graph shows the total number of publications written about "Carcinogenesis" by people in this website by year, and whether "Carcinogenesis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 3 | 10 | 13 | | 2014 | 5 | 1 | 6 | | 2015 | 2 | 3 | 5 | | 2016 | 8 | 3 | 11 | | 2017 | 7 | 5 | 12 | | 2018 | 5 | 7 | 12 | | 2019 | 5 | 12 | 17 | | 2020 | 4 | 6 | 10 | | 2021 | 0 | 7 | 7 | | 2022 | 2 | 17 | 19 | | 2023 | 1 | 5 | 6 | | 2024 | 2 | 5 | 7 | | 2025 | 5 | 3 | 8 |
To return to the timeline, click here.
Below are the most recent publications written about "Carcinogenesis" by people in Profiles.
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Callahan RC, Curry JC, Bhagavatula G, Staley AW, Schaefer RE, Minhajuddin F, Zhou L, Neuhart RM, Atif SM, Orlicky DJ, Cartwright IM, Gerich ME, Steiner CA, Theiss AL, Hall CH, Colgan SP, Onyiah JC. Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner. JCI Insight. 2026 Feb 09; 11(3).
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Haque PS, Paris SL, Souza RF, Onyiah JC, Coughlan C, Orlicky DJ, Zempleni J, Theiss AL. Obese adipose tissue-derived extracellular vesicles enriched with glycolytic cargo promote colorectal cancer tumorigenesis. Cancer Lett. 2025 Dec 28; 635:218104.
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McGivney GR, Brockman QR, Borcherding N, Scherer A, Rauckhorst AJ, Gutierrez WR, Solst SR, Heer CD, Warrier A, Floyd W, Kirsch DG, Knepper-Adrian VL, Laverty EA, Roughton GA, Spitz DR, Taylor EB, Dodd RD. Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs. Sci Adv. 2025 Aug 15; 11(33):eadu2906.
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Iyer R, Deshpande A, Pedgaonkar A, Bala PA, Kim T, Brien GL, Finlay D, Vuori K, Soragni A, Wetterstein HI, Murad R, Deshpande AJ. Targeting SUMO2 reverses aberrant epigenetic rewiring driven by SS18::SSX fusion oncoproteins and impairs sarcomagenesis. EMBO J. 2025 Sep; 44(18):4984-5004.
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Lim EL, DeGregori J. The Nature and Nurture of Carcinogenesis. Cancer Discov. 2025 Jun 03; 15(6):1090-1092.
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Sharma S, Rodems BJ, Baker CD, Kaszuba CM, Franco EI, Smith BR, Ito T, Swovick K, Welle K, Zhang Y, Rock P, Chaves FA, Ghaemmaghami S, Calvi LM, Ganguly A, Burack WR, Becker MW, Liesveld JL, Brookes PS, Munger JC, Jordan CT, Ashton JM, Bajaj J. Taurine from tumour niche drives glycolysis to promote leukaemogenesis. Nature. 2025 08; 644(8075):263-272.
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DeSisto J, Balakrishnan I, Knox AJ, Link G, Venkataraman S, Vibhakar R, Green AL. PRMT5 Maintains Tumor Stem Cells to Promote Pediatric High-Grade Glioma Tumorigenesis. Mol Cancer Res. 2025 Feb 06; 23(2):107-118.
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Kent A, Yee Mon KJ, Hutchins Z, Putzel G, Zhigarev D, Grier A, Jia B, Kortlever RM, Barbet G, Evan GI, Blander JM. A stromal inflammasome Ras safeguard against Myc-driven lymphomagenesis. Nat Immunol. 2025 Jan; 26(1):53-67.
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Flynn CL, Markey GE, Neudecker V, Farrelly C, Furuta GT, Eltzschig HK, Masterson JC, McNamee EN. The MicroRNA miR-223 Constrains Colitis-associated Tumorigenesis by Limiting Myeloid Cell Infiltration and Chemokine Expression. J Immunol. 2024 Dec 15; 213(12):1869-1883.
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Byun H, Singh GB, Xu WK, Das P, Reyes A, Battenhouse A, Wylie DC, Santiago ML, Lozano MM, Dudley JP. Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strain. PLoS Pathog. 2024 Aug; 20(8):e1012505.
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