 beta-Defensins
"beta-Defensins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DEFENSINS found mainly in epithelial cells.
| Descriptor ID |
D023083
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| MeSH Number(s) |
D12.644.050.200.075 D12.776.543.695.054.200.075
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta-Defensins".
Below are MeSH descriptors whose meaning is more specific than "beta-Defensins".
This graph shows the total number of publications written about "beta-Defensins" by people in this website by year, and whether "beta-Defensins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2013 | 3 | 0 | 3 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Defensins" by people in Profiles.
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Dos Santos JC, Heinhuis B, Gomes RS, Damen MS, Real F, Mortara RA, Keating ST, Dinarello CA, Joosten LA, Ribeiro-Dias F. Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species. PLoS Negl Trop Dis. 2017 02; 11(2):e0005413.
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Kudryashova E, Koneru PC, Kvaratskhelia M, Str?mstedt AA, Lu W, Kudryashov DS. Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins. Sci Rep. 2016 09 01; 6:32499.
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Abou Alaiwa MH, Reznikov LR, Gansemer ND, Sheets KA, Horswill AR, Stoltz DA, Zabner J, Welsh MJ. pH modulates the activity and synergism of the airway surface liquid antimicrobials ?-defensin-3 and LL-37. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):18703-8.
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Yao TC, Du G, Han L, Sun Y, Hu D, Yang JJ, Mathias R, Roth LA, Rafaels N, Thompson EE, Loisel DA, Anderson R, Eng C, Arruabarrena Orbegozo M, Young M, Klocksieben JM, Anderson E, Shanovich K, Lester LA, Williams LK, Barnes KC, Burchard EG, Nicolae DL, Abney M, Ober C. Genome-wide association study of lung function phenotypes in a founder population. J Allergy Clin Immunol. 2014 Jan; 133(1):248-55.e1-10.
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Kelly CJ, Glover LE, Campbell EL, Kominsky DJ, Ehrentraut SF, Bowers BE, Bayless AJ, Saeedi BJ, Colgan SP. Fundamental role for HIF-1a in constitutive expression of human ? defensin-1. Mucosal Immunol. 2013 Nov; 6(6):1110-8.
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Schroeder S, Robinson ZD, Masterson JC, Hosford L, Moore W, Pan Z, Harris R, Souza RF, Spechler SJ, Fillon SA, Furuta GT. Esophageal human ?-defensin expression in eosinophilic esophagitis. Pediatr Res. 2013 May; 73(5):647-54.
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Zhang W, Case S, Bowler RP, Martin RJ, Jiang D, Chu HW. Cigarette smoke modulates PGE(2) and host defence against Moraxella catarrhalis infection in human airway epithelial cells. Respirology. 2011 Apr; 16(3):508-16.
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Hata TR, Kotol P, Boguniewicz M, Taylor P, Paik A, Jackson M, Nguyen M, Kabigting F, Miller J, Gerber M, Zaccaro D, Armstrong B, Dorschner R, Leung DY, Gallo RL. History of eczema herpeticum is associated with the inability to induce human ?-defensin (HBD)-2, HBD-3 and cathelicidin in the skin of patients with atopic dermatitis. Br J Dermatol. 2010 Sep; 163(3):659-61.
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Gross CA, Bowler RP, Green RM, Weinberger AR, Schnell C, Chu HW. beta2-agonists promote host defense against bacterial infection in primary human bronchial epithelial cells. BMC Pulm Med. 2010 May 14; 10:30.
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Kisich KO, Carspecken CW, Fi?ve S, Boguniewicz M, Leung DY. Defective killing of Staphylococcus aureus in atopic dermatitis is associated with reduced mobilization of human beta-defensin-3. J Allergy Clin Immunol. 2008 Jul; 122(1):62-8.
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