 Ribonucleoprotein, U5 Small Nuclear
"Ribonucleoprotein, U5 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U5 snRNP along with U4-U6 snRNP preassemble into a single 25S particle that binds to the U1 and U2 snRNPs and the substrate to form SPLICEOSOMES.
| Descriptor ID |
D017415
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| MeSH Number(s) |
D12.776.157.725.500.875.620 D12.776.157.725.829.375 D12.776.664.962.500.875.620 D12.776.664.962.829.375
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| Concept/Terms |
Ribonucleoprotein, U5 Small Nuclear- Ribonucleoprotein, U5 Small Nuclear
- Small Nuclear Ribonucleoproteins, U5
- Ribonucleoproteins, Small, U5
- U5 snRNP
- U5 Small Nuclear Ribonucleoproteins
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Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U5 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U5 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in this website by year, and whether "Ribonucleoprotein, U5 Small Nuclear" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2013 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in Profiles.
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Liu S, Li X, Zhang L, Jiang J, Hill RC, Cui Y, Hansen KC, Zhou ZH, Zhao R. Structure of the yeast spliceosomal postcatalytic P complex. Science. 2017 12 08; 358(6368):1278-1283.
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McKay DB, Xi L, Barthel KKB, Cech TR. Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA. J Mol Biol. 2014 Apr 17; 426(8):1766-1785.
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De Arras L, Laws R, Leach SM, Pontis K, Freedman JH, Schwartz DA, Alper S. Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity. Genetics. 2014 Jun; 197(2):485-96.
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Li X, Zhang W, Xu T, Ramsey J, Zhang L, Hill R, Hansen KC, Hesselberth JR, Zhao R. Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly. Nucleic Acids Res. 2013 Apr 01; 41(6):3805-18.
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Zhang L, Xu T, Maeder C, Bud LO, Shanks J, Nix J, Guthrie C, Pleiss JA, Zhao R. Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat Struct Mol Biol. 2009 Jul; 16(7):731-9.
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Yang K, Zhang L, Xu T, Heroux A, Zhao R. Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13817-22.
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Br?s V, Gomes N, Pickle L, Jones KA. A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. Genes Dev. 2005 May 15; 19(10):1211-26.
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Frank DN, Roiha H, Guthrie C. Architecture of the U5 small nuclear RNA. Mol Cell Biol. 1994 Mar; 14(3):2180-90.
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