 Introns
"Introns" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.
| Descriptor ID |
D007438
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| MeSH Number(s) |
G05.360.340.024.220.400 G05.360.340.024.340.137.515
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| Concept/Terms |
Introns- Introns
- Intron
- Sequences, Intervening
- Intervening Sequence
- Sequence, Intervening
- Intervening Sequences
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Below are MeSH descriptors whose meaning is more general than "Introns".
Below are MeSH descriptors whose meaning is more specific than "Introns".
This graph shows the total number of publications written about "Introns" by people in this website by year, and whether "Introns" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 4 | 8 | 12 | | 1996 | 4 | 5 | 9 | | 1997 | 4 | 8 | 12 | | 1998 | 1 | 6 | 7 | | 1999 | 0 | 7 | 7 | | 2000 | 0 | 2 | 2 | | 2001 | 0 | 2 | 2 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 5 | 5 | | 2004 | 2 | 5 | 7 | | 2005 | 1 | 3 | 4 | | 2006 | 0 | 3 | 3 | | 2007 | 3 | 4 | 7 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 6 | 6 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 4 | 5 | | 2014 | 3 | 3 | 6 | | 2015 | 0 | 5 | 5 | | 2016 | 0 | 4 | 4 | | 2017 | 0 | 2 | 2 | | 2018 | 1 | 2 | 3 | | 2019 | 2 | 1 | 3 | | 2020 | 0 | 1 | 1 | | 2021 | 2 | 2 | 4 | | 2022 | 1 | 2 | 3 | | 2023 | 0 | 5 | 5 | | 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Introns" by people in Profiles.
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Starosta RT, Larson AA, Meeks NJL, Gracie S, Friederich MW, Gaughan SM, Baker PR, Knupp KG, Michel CR, Reisdorph R, Hock DH, Stroud DA, Wood T, Van Hove JLK. An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis. Mitochondrion. 2024 Nov; 79:101973.
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Earley EJ, D'Alessandro A, Kaestner L, Page GP. Reply to McGowan et al.: An intronic polymorphism associated with 2,3-bisphosphoglycerate levels in human red blood cells is linked to expression of RhCE blood groups. Proc Natl Acad Sci U S A. 2024 Sep 03; 121(36):e2413726121.
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G?k V, Leblebisatan G, G?rlek G?k?ebay D, G?ler S, Dogan ME, Tug Bozdogan S, Koca Yozgat A, ?zcan A, Pekpak Sahinoglu E, Tokg?z H, ?il M, ?zemri Sag S, Yilmaz E, Sasmaz HI, Evim MS, Akbayram S, Karadogan M, Mutlu FT, Boga I, Yeter Dogan B, Yarali N, ?aliskan ?, Bisgin A, Temel SG, Proven M, Gibson K, Demir BS, Sara?oglu H, Eken A, Karak?k?? ?, Karak?k?? M, G?nes AM, ?zbek NY, Kilin? Y, Patiroglu T, ?zdemir MA, Roy NBA, ?nal E. Pyruvate kinase deficiency in 29 Turkish patients with two novel intronic variants. Br J Haematol. 2024 Jul; 205(1):236-242.
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Wethekam LC, Moore JK. a-tubulin regulation by 5' introns in Saccharomyces cerevisiae. Genetics. 2023 12 06; 225(4).
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Shenasa H, Bentley DL. Pre-mRNA splicing and its cotranscriptional connections. Trends Genet. 2023 09; 39(9):672-685.
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Borovsky D, Roug? P. Cloning and characterization of Aedes aegypti blood downregulated chymotrypsin II. Arch Insect Biochem Physiol. 2023 Jul; 113(3):e22018.
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Rodden LN, Rummey C, Kessler S, Wilson RB, Lynch DR. A Novel Metric for Predicting Severity of Disease Features in Friedreich's Ataxia. Mov Disord. 2023 06; 38(6):970-977.
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Riemondy K, Henriksen JC, Rissland OS. Intron dynamics reveal principles of gene regulation during the maternal-to-zygotic transition. RNA. 2023 05; 29(5):596-608.
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Bachu VS, Kandoi S, Park KU, Kaufman ML, Schwanke M, Lamba DA, Brzezinski JA. An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas. Dev Biol. 2022 08; 488:131-150.
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Waldrop MA, Moore SA, Mathews KD, Darbro BW, Medne L, Finkel R, Connolly AM, Crawford TO, Drachman D, Wein N, Habib AA, Krzesniak-Swinarska MA, Zaidman CM, Collins JJ, Jokela M, Udd B, Day JW, Ortiz-Guerrero G, Statland J, Butterfield RJ, Dunn DM, Weiss RB, Flanigan KM. Intron mutations and early transcription termination in Duchenne and Becker muscular dystrophy. Hum Mutat. 2022 04; 43(4):511-528.
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