 Introns
"Introns" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.
| Descriptor ID |
D007438
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| MeSH Number(s) |
G05.360.340.024.220.400 G05.360.340.024.340.137.515
|
| Concept/Terms |
Introns- Introns
- Intron
- Sequences, Intervening
- Intervening Sequence
- Sequence, Intervening
- Intervening Sequences
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Below are MeSH descriptors whose meaning is more general than "Introns".
Below are MeSH descriptors whose meaning is more specific than "Introns".
This graph shows the total number of publications written about "Introns" by people in this website by year, and whether "Introns" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 5 | 4 | 9 | | 1995 | 4 | 9 | 13 | | 1996 | 4 | 5 | 9 | | 1997 | 4 | 8 | 12 | | 1998 | 1 | 6 | 7 | | 1999 | 0 | 7 | 7 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 5 | 5 | | 2004 | 1 | 5 | 6 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 3 | 3 | | 2007 | 3 | 4 | 7 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 6 | 6 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 4 | 5 | | 2014 | 3 | 3 | 6 | | 2015 | 0 | 6 | 6 | | 2016 | 0 | 4 | 4 | | 2017 | 0 | 2 | 2 | | 2018 | 1 | 2 | 3 | | 2019 | 2 | 1 | 3 | | 2020 | 0 | 1 | 1 | | 2021 | 1 | 3 | 4 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 5 | 5 |
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Below are the most recent publications written about "Introns" by people in Profiles.
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Wethekam LC, Moore JK. a-tubulin regulation by 5' introns in Saccharomyces cerevisiae. Genetics. 2023 Dec 06; 225(4).
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Shenasa H, Bentley DL. Pre-mRNA splicing and its cotranscriptional connections. Trends Genet. 2023 09; 39(9):672-685.
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Borovsky D, Roug? P. Cloning and characterization of Aedes aegypti blood downregulated chymotrypsin II. Arch Insect Biochem Physiol. 2023 Jul; 113(3):e22018.
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Rodden LN, Rummey C, Kessler S, Wilson RB, Lynch DR. A Novel Metric for Predicting Severity of Disease Features in Friedreich's Ataxia. Mov Disord. 2023 06; 38(6):970-977.
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Riemondy K, Henriksen JC, Rissland OS. Intron dynamics reveal principles of gene regulation during the maternal-to-zygotic transition. RNA. 2023 05; 29(5):596-608.
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Bachu VS, Kandoi S, Park KU, Kaufman ML, Schwanke M, Lamba DA, Brzezinski JA. An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas. Dev Biol. 2022 08; 488:131-150.
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Carranza F, Shenasa H, Hertel KJ. Splice site proximity influences alternative exon definition. RNA Biol. 2022 01; 19(1):829-840.
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Pinto EM, Maxwell KN, Halalsheh H, Phillips A, Powers J, MacFarland S, Walsh MF, Breen K, Formiga MN, Kriwacki R, Nichols KE, Mostafavi R, Wang J, Clay MR, Rodriguez-Galindo C, Ribeiro RC, Zambetti GP. Clinical and Functional Significance of TP53 Exon 4-Intron 4 Splice Junction Variants. Mol Cancer Res. 2022 02; 20(2):207-216.
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Danis D, Jacobsen JOB, Carmody LC, Gargano MA, McMurry JA, Hegde A, Haendel MA, Valentini G, Smedley D, Robinson PN. Interpretable prioritization of splice variants in diagnostic next-generation sequencing. Am J Hum Genet. 2021 09 02; 108(9):1564-1577.
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Dumbovic G, Braunschweig U, Langner HK, Smallegan M, Biayna J, Hass EP, Jastrzebska K, Blencowe B, Cech TR, Caruthers MH, Rinn JL. Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention. Nat Commun. 2021 06 03; 12(1):3308.
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