 Computational Biology
"Computational Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
| Descriptor ID |
D019295
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| MeSH Number(s) |
H01.158.273.180 L01.313.124
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| Concept/Terms |
Computational Molecular Biology- Computational Molecular Biology
- Biologies, Computational Molecular
- Biology, Computational Molecular
- Computational Molecular Biologies
- Molecular Biologies, Computational
- Molecular Biology, Computational
Bio-Informatics- Bio-Informatics
- Bio Informatics
- Bio-Informatic
- Bioinformatics
- Bioinformatic
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Below are MeSH descriptors whose meaning is more general than "Computational Biology".
Below are MeSH descriptors whose meaning is more specific than "Computational Biology".
This graph shows the total number of publications written about "Computational Biology" by people in this website by year, and whether "Computational Biology" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 3 | 5 | 8 | | 2003 | 4 | 6 | 10 | | 2004 | 2 | 8 | 10 | | 2005 | 5 | 5 | 10 | | 2006 | 6 | 9 | 15 | | 2007 | 7 | 5 | 12 | | 2008 | 11 | 4 | 15 | | 2009 | 13 | 9 | 22 | | 2010 | 6 | 9 | 15 | | 2011 | 6 | 16 | 22 | | 2012 | 5 | 16 | 21 | | 2013 | 10 | 13 | 23 | | 2014 | 7 | 16 | 23 | | 2015 | 10 | 12 | 22 | | 2016 | 16 | 19 | 35 | | 2017 | 18 | 15 | 33 | | 2018 | 8 | 23 | 31 | | 2019 | 17 | 23 | 40 | | 2020 | 6 | 23 | 29 | | 2021 | 16 | 21 | 37 | | 2022 | 4 | 3 | 7 | | 2023 | 6 | 3 | 9 | | 2024 | 5 | 11 | 16 | | 2025 | 16 | 5 | 21 |
To return to the timeline, click here.
Below are the most recent publications written about "Computational Biology" by people in Profiles.
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Liu X, Tang YH, Blachly J, Edge S, Jakubek YA, McCarter M, Naqash AR, Nepple KG, Osman A, Reilley MJ, Riedlinger G, Salhia B, Schneider BP, Shriver C, Churchman ML, Rounbehler RJ, Teer JK, Gillis N, Teng M. qcCHIP: an R package to identify clonal hematopoiesis variants using cohort-specific data characteristics. Bioinformatics. 2025 Sep 01; 41(9).
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Reynoso S, Schiebout C, Krishna R, Zhang F. STEAM: Spatial Transcriptomics Evaluation Algorithm and Metric for clustering performance. Brief Bioinform. 2025 Aug 31; 26(5).
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Ghosh T, Baxter RM, Seal S, Lui VG, Rudra P, Vu T, Hsieh EWY, Ghosh D. cytoKernel: robust kernel embeddings for assessing differential expression of single-cell data. Bioinformatics. 2025 Jul 01; 41(7).
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Gillenwater LA, Hunter LE, Costello JC. GRACKLE: an interpretable matrix factorization approach for biomedical representation learning. Bioinformatics. 2025 Jul 01; 41(Supplement_1):i609-i618.
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Okolovitch EM, Govindarajan V, Robles-Sikisaka R, Campagnola G, Kempf BJ, Routh AL, Peersen OB, Barton DJ. Enterovirus C recombination groups: RNA sequence similarity and the viral polymerase underpin sexual replication mechanisms. J Virol. 2025 Jul 22; 99(7):e0043425.
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Kalinin AA, Arevalo J, Serrano E, Vulliard L, Tsang H, Bornholdt M, Muñoz AF, Sivagurunathan S, Rajwa B, Carpenter AE, Way GP, Singh S. A versatile information retrieval framework for evaluating profile strength and similarity. Nat Commun. 2025 Jun 04; 16(1):5181.
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Sun L, Ma Q, Cai C, Labaf M, Jain A, Dias C, Rockowitz S, Sliz P. scDown: A Pipeline for Single-Cell RNA-Seq Downstream Analysis. Int J Mol Sci. 2025 May 30; 26(11).
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Botvinik-Nezer R, Geuter S, Lindquist MA, Wager TD. Expectation generation and its effect on subsequent pain and visual perception. PLoS Comput Biol. 2025 May; 21(5):e1013053.
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Fazal S, Dashnow H, Dohrn MF, Raposo J, Hiatt L, Danzi MC, Xu IRL, Toro C, Adams DR, Usdin K, Hayward B, Kobren SN, Sunyaev SR, Spillmann RC, Shashi V, Rebelo A, Bademci G, Tekin M, Quinlan AR, Zuchner S. A genome-wide approach for the discovery of novel repeat expansion disorders in the Undiagnosed Diseases Network cohort. Genet Med. 2025 Aug; 27(8):101462.
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Goldmann U, Wiedmer T, Garofoli A, Sedlyarov V, Bichler M, Haladik B, Wolf G, Christodoulaki E, Ingles-Prieto A, Ferrada E, Frommelt F, Teoh ST, Leippe P, Onea G, Pfeifer M, Kohlbrenner M, Chang L, Selzer P, Reinhardt J, Digles D, Ecker GF, Osthushenrich T, MacNamara A, Malarstig A, Hepworth D, Superti-Furga G. Data- and knowledge-derived functional landscape of human solute carriers. Mol Syst Biol. 2025 Jun; 21(6):599-631.
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