 Computational Biology
"Computational Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
| Descriptor ID |
D019295
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| MeSH Number(s) |
H01.158.273.180 L01.313.124
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| Concept/Terms |
Computational Molecular Biology- Computational Molecular Biology
- Biologies, Computational Molecular
- Biology, Computational Molecular
- Computational Molecular Biologies
- Molecular Biologies, Computational
- Molecular Biology, Computational
Bio-Informatics- Bio-Informatics
- Bio Informatics
- Bio-Informatic
- Bioinformatics
- Bioinformatic
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Below are MeSH descriptors whose meaning is more general than "Computational Biology".
Below are MeSH descriptors whose meaning is more specific than "Computational Biology".
This graph shows the total number of publications written about "Computational Biology" by people in this website by year, and whether "Computational Biology" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 3 | 5 | 8 | | 2003 | 4 | 6 | 10 | | 2004 | 2 | 8 | 10 | | 2005 | 5 | 5 | 10 | | 2006 | 6 | 9 | 15 | | 2007 | 7 | 5 | 12 | | 2008 | 12 | 4 | 16 | | 2009 | 13 | 9 | 22 | | 2010 | 7 | 10 | 17 | | 2011 | 6 | 15 | 21 | | 2012 | 5 | 16 | 21 | | 2013 | 10 | 14 | 24 | | 2014 | 7 | 17 | 24 | | 2015 | 10 | 13 | 23 | | 2016 | 15 | 19 | 34 | | 2017 | 19 | 17 | 36 | | 2018 | 8 | 24 | 32 | | 2019 | 17 | 23 | 40 | | 2020 | 6 | 21 | 27 | | 2021 | 16 | 21 | 37 | | 2022 | 4 | 3 | 7 | | 2023 | 6 | 4 | 10 | | 2024 | 6 | 10 | 16 | | 2025 | 20 | 8 | 28 | | 2026 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Computational Biology" by people in Profiles.
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Burke D, Raychaudhuri J, Chuong E, Taylor W, Layer R. TEPEAK: A novel method for identifying and characterizing polymorphic transposable elements in non-model species populations. PLoS Comput Biol. 2026 Jan; 22(1):e1013122.
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Fouquier J, Stanislawski M, O'Connor J, Scadden A, Lozupone C. EXPLANA: a user-friendly workflow for EXPLoratory ANAlysis and feature selection in cross-sectional and longitudinal microbiome studies. Bioinformatics. 2026 Jan 02; 42(1).
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Lyons R, Dukic V, Bortz DM. Learning structured population models from data with WSINDy. PLoS Comput Biol. 2025 Dec; 21(12):e1013742.
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Sears JD, Popov KI, Sylvester PA, Dickmander R, Diaz J, Chang CK, Huff J, Sanders W, Saba NA, Sorensen M, Drobish AM, May NA, Namitz K, Fecko J, Yennawar NH, Morrison TE, Tropsha A, Heise MT, Moorman NJ. Novel computational pipeline to identify target sites for broad spectrum antiviral drugs. Antiviral Res. 2026 Jan; 245:106322.
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Pavelka J, Voong CK, Schaal P, Lam MPY, Lau E. SALVE: prediction of interorgan communication with transcriptome latent space representation. Am J Physiol Heart Circ Physiol. 2025 Dec 01; 329(6):H1621-H1632.
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Komp E, Johansson KE, Gauthier NP, Gado JE, Lindorff-Larsen K, Beckham GT. Accessible, uniform protein property prediction with a scikit-learn based toolset AIDE. Bioinformatics. 2025 Oct 02; 41(10).
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Pitsch JW, Wirth SA, Costantino NT, Mejia J, Doss RM, Warren AVA, Ustanik J, Yang X, Breuss MW. CREPE (CREate Primers and Evaluate): A Computational Tool for Large-Scale Primer Design and Specificity Analysis. Genes (Basel). 2025 Sep 10; 16(9).
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Liu X, Tang YH, Blachly J, Edge S, Jakubek YA, McCarter M, Naqash AR, Nepple KG, Osman A, Reilley MJ, Riedlinger G, Salhia B, Schneider BP, Shriver C, Churchman ML, Rounbehler RJ, Teer JK, Gillis N, Teng M. qcCHIP: an R package to identify clonal hematopoiesis variants using cohort-specific data characteristics. Bioinformatics. 2025 Sep 01; 41(9).
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Reynoso S, Schiebout C, Krishna R, Zhang F. STEAM: Spatial Transcriptomics Evaluation Algorithm and Metric for clustering performance. Brief Bioinform. 2025 Aug 31; 26(5).
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Ghosh T, Baxter RM, Seal S, Lui VG, Rudra P, Vu T, Hsieh EWY, Ghosh D. cytoKernel: robust kernel embeddings for assessing differential expression of single-cell data. Bioinformatics. 2025 Jul 01; 41(7).
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