Computational Biology
"Computational Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
| Descriptor ID |
D019295
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| MeSH Number(s) |
H01.158.273.180 L01.313.124
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| Concept/Terms |
Computational Molecular Biology- Computational Molecular Biology
- Biologies, Computational Molecular
- Biology, Computational Molecular
- Computational Molecular Biologies
- Molecular Biologies, Computational
- Molecular Biology, Computational
Bio-Informatics- Bio-Informatics
- Bio Informatics
- Bio-Informatic
- Bioinformatics
- Bioinformatic
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Below are MeSH descriptors whose meaning is more general than "Computational Biology".
Below are MeSH descriptors whose meaning is more specific than "Computational Biology".
This graph shows the total number of publications written about "Computational Biology" by people in this website by year, and whether "Computational Biology" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 3 | 5 | 8 | | 2003 | 4 | 6 | 10 | | 2004 | 3 | 8 | 11 | | 2005 | 5 | 5 | 10 | | 2006 | 6 | 9 | 15 | | 2007 | 7 | 7 | 14 | | 2008 | 12 | 4 | 16 | | 2009 | 13 | 9 | 22 | | 2010 | 7 | 10 | 17 | | 2011 | 7 | 16 | 23 | | 2012 | 6 | 15 | 21 | | 2013 | 10 | 15 | 25 | | 2014 | 8 | 16 | 24 | | 2015 | 10 | 14 | 24 | | 2016 | 15 | 19 | 34 | | 2017 | 19 | 17 | 36 | | 2018 | 8 | 25 | 33 | | 2019 | 17 | 23 | 40 | | 2020 | 6 | 23 | 29 | | 2021 | 16 | 20 | 36 | | 2022 | 5 | 3 | 8 | | 2023 | 6 | 4 | 10 | | 2024 | 6 | 11 | 17 | | 2025 | 21 | 10 | 31 | | 2026 | 5 | 7 | 12 |
To return to the timeline, click here.
Below are the most recent publications written about "Computational Biology" by people in Profiles.
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DeRoo J, Terry JS, Zhao N, Stasevich TJ, Snow C, Geiss BJ. Linear antibody epitope prediction using AlphaFold2. Elife. 2026 Sep 18; 13.
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Andersen SE, Kirsch JM, Singh N, Garrett SR, Whitney JC, Hesselberth JR, Duerkop BA. Small serine recombinases are markers for antiphage defense system discovery. PLoS Biol. 2026 Aug; 24(8):e3003991.
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McKim A, Mancuso CA, Krishnan A. A module-based approach for post-omics, post-GWAS network-based gene classification. Bioinformatics. 2026 Aug 03; 42(8).
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Benthal JT, Avila JA, Smith JR, Southard-Smith EM. Combinatorial multiomic analysis from a pedigree of Sox10Dom Hirschsprung mice identifies multiple high confidence candidate modifiers of Enteric Nervous System development. PLoS Comput Biol. 2026 Jul; 22(7):e1014424.
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Tholo N, Markey G, Harrigan R, Pandey P, Prasad B, Barai RS, Gibson DS, Shukla P. The critical role of artificial intelligence and bioinformatics in accelerating peptide-based vaccine discovery for tackling global infectious diseases. Brief Bioinform. 2026 Jul 03; 27(4).
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Montgomery D, Barrientos ES, Grdadolnik JM, Hendrickson K, Fogelson AL, Neeves KB, Leiderman K. A three-dimensional shear dependent continuum model of platelet aggregation under flow. PLoS Comput Biol. 2026 May; 22(5):e1014241.
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Zhang Y, Zhang H, Akashi H, Albouy CP, Andres KJ, Barquín J, Brantschen J, Connon RE, Craine JM, Gleeson D, Goldenberg-Vilar A, González-Ferreras AM, Hatzenbuhler C, Hupalo K, Hyde J, Iwasaki W, Johnson MD, Katz AD, Kuzovlev VV, Larson CE, Lecaudey LA, Leese F, Leray M, Li F, Macher TH, Mauvisseau Q, Morán-Luis M, Nester G, Quintero H, Ravelomanana T, Chacko MR, Saccò M, Sales N, Schenekar T, Schletterer M, Schmidt S, Schulte NO, Schütz R, Sperry JH, Stevens ER, Stinson SA, Weiss S, Xia F, Zhang H, Zhang S, Zhong W, Zong S, Pellissier L, Zhang X, Altermatt F. Integrated Reanalysis of Global Riverine Fish eDNA Datasets Shows Robustness and Congruence of Biodiversity Conclusions. Mol Ecol. 2026 Apr; 35(8):e70340.
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Heitzman-Breen N, Dukic V, Bortz DM. A Practical Identifiability Criterion Leveraging Weak-Form Parameter Estimation. Bull Math Biol. 2026 Mar 31; 88(5).
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Serrano E, Peters J, Wagner J, Graham RE, Chen Z, Feng BY, Miranda G, Kalinin AA, Vulliard L, Tomkinson J, Mattson C, Lippincott MJ, Kang Z, Sitani D, Bunten D, Seal S, Carragher NO, Carpenter AE, Singh S, Marin Zapata PA, Caicedo JC, Way GP. Progress and new challenges in image-based profiling. Mol Syst Biol. 2026 May; 22(5):624-658.
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Ai HW, Arnold FH, Barrick D, Bayley H, Brownless AR, Campbell RE, Castells-Graells R, Chaiyen P, Chica RA, Chisholm LO, Christ D, Chu GC, Chungyoun M, Eijsink VGH, Elowitz MB, Fansher DJ, Fasan R, Foley G, Frei MS, Gagsteiger A, Gao R, Gillam EMJ, Gray JJ, Guerra LF, Höcker B, Jin Z, Kamerlin SCL, Koga N, Kontermann RE, Kuhlman B, Langlois OA, Li D, Lins RD, Liu CC, Liu L, López Barreiro D, Lu P, Mehta S, Miyazaki I, Müller MM, Muyldermans S, Nemoto N, Nivala J, Nuñez JK, Ornelas IJ, Pelletier JN, Plückthun A, Porth OT, Prakinee K, Qing Y, Reisenbauer JC, Schmidt S, Seifert O, Shapiro MG, Sharma R, Singh N, Smith BJ, Spangler JB, Tatsumi-Koga R, Terai T, Terholsen H, Tolhurst M, Tripp KW, Trossmann VT, Tucker CL, Turak O, Van Deventer JA, Várnai A, Viana IFT, Weeks AM, Wittrup KD, Wong KL, Xi C, Yeates TO, Yeh AH, Zhang J, Zhang TS, Zhao H, Zheng F, Zhu J, Zinn S. Protein engineering: status report. Protein Eng Des Sel. 2026 Jan 09; 39.
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