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																		 RNA Splicing
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"RNA Splicing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm.
    
			 
				
				
					
						| Descriptor ID | D012326 |  
						| MeSH Number(s) | G02.111.760.700 G03.839.700 G05.308.700.700 |  
						| Concept/Terms | RNA SplicingRNA SplicingSplicing, RNARNA SplicingsSplicings, RNA
 |  
				Below are MeSH descriptors whose meaning is more general than "RNA Splicing". 
				Below are MeSH descriptors whose meaning is more specific than "RNA Splicing". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "RNA Splicing" by people in this website by year, and whether "RNA Splicing" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 3 | 3 | 6 |  | 1996 | 3 | 5 | 8 |  | 1997 | 0 | 6 | 6 |  | 1998 | 0 | 1 | 1 |  | 1999 | 1 | 1 | 2 |  | 2000 | 1 | 1 | 2 |  | 2001 | 1 | 0 | 1 |  | 2002 | 1 | 3 | 4 |  | 2003 | 1 | 2 | 3 |  | 2004 | 2 | 2 | 4 |  | 2005 | 1 | 2 | 3 |  | 2006 | 1 | 0 | 1 |  | 2007 | 3 | 1 | 4 |  | 2008 | 1 | 0 | 1 |  | 2009 | 0 | 2 | 2 |  | 2010 | 0 | 2 | 2 |  | 2011 | 2 | 2 | 4 |  | 2013 | 2 | 0 | 2 |  | 2014 | 5 | 4 | 9 |  | 2015 | 1 | 6 | 7 |  | 2016 | 2 | 2 | 4 |  | 2017 | 5 | 5 | 10 |  | 2018 | 1 | 4 | 5 |  | 2019 | 4 | 3 | 7 |  | 2020 | 3 | 2 | 5 |  | 2021 | 0 | 4 | 4 |  | 2022 | 2 | 4 | 6 |  | 2023 | 0 | 2 | 2 |  | 2024 | 2 | 1 | 3 |  | 2025 | 0 | 3 | 3 | 
 
                    To return to the timeline, click here. 
				Below are the most recent publications written about "RNA Splicing" by people in Profiles. 		
					
								
								Pereira IT, Mamede I, Amaral PP, Franco GR, Rinn JL. Widespread specific intron retention events in nuclear RNA complexes identified by sedimentation analysis of pluripotent cellular extracts. Genome Res. 2025 Oct 01; 35(10):2189-2198.
								Forouzanfar F, Moreno DF, Plassard D, Furst A, Oliveira KA, Reina-San-Martin B, Tora L, Molina N, Mendoza M. Gene-specific transcript buffering revealed by perturbation of coactivator complexes. Sci Adv. 2025 Mar 21; 11(12):eadr1492.
								Shi S, Zhao R. RNA-Binding Proteins (RBPs) and Circular RNA Biogenesis. Adv Exp Med Biol. 2025; 1485:117-130.
								Shi S, Zhao R. How does the spliceosome dismantle itself? Nature. 2024 08; 632(8024):261-262.
								Chalivendra S, Shi S, Li X, Kuang Z, Giovinazzo J, Zhang L, Rossi J, Wang J, Saviola AJ, Welty R, Liu S, Vaeth KF, Zhou ZH, Hansen KC, Taliaferro JM, Zhao R. Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast. RNA. 2024 07 16; 30(8):1070-1088.
								Li D, Wang Q, Bayat A, Battig MR, Zhou Y, Bosch DG, van Haaften G, Granger L, Petersen AK, Pérez-Jurado LA, Aznar-Laín G, Aneja A, Hancarova M, Bendova S, Schwarz M, Kremlikova Pourova R, Sedlacek Z, Keena BA, March ME, Hou C, O'Connor N, Bhoj EJ, Harr MH, Lemire G, Boycott KM, Towne M, Li M, Tarnopolsky M, Brady L, Parker MJ, Faghfoury H, Parsley LK, Agolini E, Dentici ML, Novelli A, Wright M, Palmquist R, Lai K, Scala M, Striano P, Iacomino M, Zara F, Cooper A, Maarup TJ, Byler M, Lebel RR, Balci TB, Louie R, Lyons M, Douglas J, Nowak C, Afenjar A, Hoyer J, Keren B, Maas SM, Motazacker MM, Martinez-Agosto JA, Rabani AM, McCormick EM, Falk MJ, Ruggiero SM, Helbig I, Møller RS, Tessarollo L, Tomassoni Ardori F, Palko ME, Hsieh TC, Krawitz PM, Ganapathi M, Gelb BD, Jobanputra V, Wilson A, Greally J, Jacquemont S, Jizi K, Bruel AL, Quelin C, Misra VK, Chick E, Romano C, Greco D, Arena A, Morleo M, Nigro V, Seyama R, Uchiyama Y, Matsumoto N, Taira R, Tashiro K, Sakai Y, Yigit G, Wollnik B, Wagner M, Kutsche B, Hurst AC, Thompson ML, Schmidt R, Randolph L, Spillmann RC, Shashi V, Higginbotham EJ, Cordeiro D, Carnevale A, Costain G, Khan T, Funalot B, Tran Mau-Them F, Fernandez Garcia Moya L, García-Miñaúr S, Osmond M, Chad L, Quercia N, Carrasco D, Li C, Sanchez-Valle A, Kelley M, Nizon M, Jensson BO, Sulem P, Stefansson K, Gorokhova S, Busa T, Rio M, Hadj Habdallah H, Lesieur-Sebellin M, Amiel J, Pingault V, Mercier S, Vincent M, Philippe C, Fatus-Fauconnier C, Friend K, Halligan RK, Biswas S, Rosser J, Shoubridge C, Corbett M, Barnett C, Gecz J, Leppig K, Slavotinek A, Marcelis C, Pfundt R, de Vries BB, van Slegtenhorst MA, Brooks AS, Cogne B, Rambaud T, Tümer Z, Zackai EH, Akizu N, Song Y, Hakonarson H. Spliceosome malfunction causes neurodevelopmental disorders with overlapping features. J Clin Invest. 2024 01 02; 134(1).
								Gurule NJ, Malcolm KC, Harris C, Knapp JR, O'Connor BP, McClendon J, Janssen WJ, Lee FFY, Price C, Osaghae-Nosa J, Wheeler EA, McMahon CM, Pietras EM, Pollyea DA, Alper S. Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis. Leukemia. 2023 10; 37(10):2115-2124.
								Shenasa H, Bentley DL. Pre-mRNA splicing and its cotranscriptional connections. Trends Genet. 2023 09; 39(9):672-685.
								Lee FFY, Alper S. Alternative pre-mRNA splicing as a mechanism for terminating Toll-like Receptor signaling. Front Immunol. 2022; 13:1023567.
								Le BT, Paul S, Jastrzebska K, Langer H, Caruthers MH, Veedu RN. Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2207956119. | 
																	
																		
																			
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