Chaperonin 60
"Chaperonin 60" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group I chaperonin protein that forms the barrel-like structure of the chaperonin complex. It is an oligomeric protein with a distinctive structure of fourteen subunits, arranged in two rings of seven subunits each. The protein was originally studied in BACTERIA where it is commonly referred to as GroEL protein.
Descriptor ID |
D018834
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MeSH Number(s) |
D08.811.277.040.025.142.500.500 D12.776.580.216.210.590.750
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Concept/Terms |
Chaperonin 60- Chaperonin 60
- hsp60 Family
- Heat-Shock Proteins 60
- Heat Shock Proteins 60
- hsp60 Protein
- Heat-Shock Protein 60
- Heat Shock Protein 60
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Below are MeSH descriptors whose meaning is more general than "Chaperonin 60".
Below are MeSH descriptors whose meaning is more specific than "Chaperonin 60".
This graph shows the total number of publications written about "Chaperonin 60" by people in this website by year, and whether "Chaperonin 60" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2001 | 0 | 1 | 1 | 2003 | 1 | 2 | 3 | 2004 | 1 | 0 | 1 | 2006 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2015 | 1 | 1 | 2 | 2016 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chaperonin 60" by people in Profiles.
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Walsh CM, Gebert MJ, Delgado-Baquerizo M, Maestre FT, Fierer N. A Global Survey of Mycobacterial Diversity in Soil. Appl Environ Microbiol. 2019 09 01; 85(17).
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Marino Gammazza A, Campanella C, Barone R, Caruso Bavisotto C, Gorska M, Wozniak M, Carini F, Cappello F, D'Anneo A, Lauricella M, Zummo G, Conway de Macario E, Macario AJ, Di Felice V. Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence. Cancer Lett. 2017 01 28; 385:75-86.
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Ledreux A, Boger HA, Hinson VK, Cantwell K, Granholm AC. BDNF levels are increased by aminoindan and rasagiline in a double lesion model of Parkinson?s disease. Brain Res. 2016 Jan 15; 1631:34-45.
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Chitradevi ST, Kaur G, Uppalapati S, Yadav A, Singh D, Bansal A. Co-administration of rIpaB domain of Shigella with rGroEL of S. Typhi enhances the immune responses and protective efficacy against Shigella infection. Cell Mol Immunol. 2015 Nov; 12(6):757-67.
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Gorska M, Marino Gammazza A, Zmijewski MA, Campanella C, Cappello F, Wasiewicz T, Kuban-Jankowska A, Daca A, Sielicka A, Popowska U, Knap N, Antoniewicz J, Wakabayashi T, Wozniak M. Geldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60). PLoS One. 2013; 8(8):e71135.
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Shin YS, Takeda K, Shiraishi Y, Jeong YY, Domenico J, Jia Y, Han J, Spallek R, Singh M, Lucas JJ, Gelfand EW. Microbial heat shock protein 65 attenuates airway hyperresponsiveness and inflammation by modulating the function of dendritic cells. J Immunol. 2012 Oct 01; 189(7):3404-10.
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De Carlo S, Boisset N, Hoenger A. High-resolution single-particle 3D analysis on GroEL prepared by cryo-negative staining. Micron. 2008 Oct; 39(7):934-43.
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Brown V, Brown RA, Ozinsky A, Hesselberth JR, Fields S. Binding specificity of Toll-like receptor cytoplasmic domains. Eur J Immunol. 2006 Mar; 36(3):742-53.
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George R, Kelly SM, Price NC, Erbse A, Fisher M, Lund PA. Three GroEL homologues from Rhizobium leguminosarum have distinct in vitro properties. Biochem Biophys Res Commun. 2004 Nov 12; 324(2):822-8.
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Schloot NC, Meierhoff G, Karlsson Faresj? M, Ott P, Putnam A, Lehmann P, Gottlieb P, Roep BO, Peakman M, Tree T. Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop. J Autoimmun. 2003 Dec; 21(4):365-76.
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