 Nucleosomes
"Nucleosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core. This core is composed of the histones H2A, H2B, H3, and H4.
| Descriptor ID |
D009707
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| MeSH Number(s) |
A11.284.430.106.279.345.190.160.180.625 D12.776.664.224.550 G05.360.160.180.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleosomes".
Below are MeSH descriptors whose meaning is more specific than "Nucleosomes".
This graph shows the total number of publications written about "Nucleosomes" by people in this website by year, and whether "Nucleosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 1998 | 0 | 1 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 2 | 2 | 4 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 2 | 1 | 3 | | 2011 | 6 | 0 | 6 | | 2012 | 1 | 1 | 2 | | 2013 | 5 | 2 | 7 | | 2014 | 5 | 3 | 8 | | 2015 | 3 | 1 | 4 | | 2016 | 2 | 5 | 7 | | 2017 | 9 | 4 | 13 | | 2018 | 8 | 3 | 11 | | 2019 | 3 | 2 | 5 | | 2020 | 1 | 6 | 7 | | 2021 | 7 | 5 | 12 | | 2022 | 3 | 2 | 5 | | 2023 | 0 | 2 | 2 | | 2024 | 4 | 2 | 6 | | 2025 | 4 | 1 | 5 | | 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nucleosomes" by people in Profiles.
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Fuchs HA, Peng Y, Ayyapan S, Rosas R, Zhang H, Panchenko AR, Musselman CA. G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails. Nucleic Acids Res. 2026 Jan 14; 54(2).
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Marunde MR, Popova IK, Hall NW, Vaidya A, Bone JR, Boone BA, Brown PJ, Ezell RJ, Firestone TM, Fuchs HA, Gibson E, Gillespie ZB, Gloor SL, Hickman AR, Howard SA, Husby NL, Hsiung VT, Johnstone AL, Khan LF, Krajewski K, Lee AS, McAnarney ET, Maier KE, Maryanski DN, McCuiston JL, Noll KE, Novitzky K, Patteson EF, Rodriguez KL, Sanchez JC, Schachner LF, Smith CE, Sun L, Taylor HF, Watson R, Willis HE, Musselman CA, Venters BJ, Cheek MA, Meiners MJ, Sun ZW, Kelleher NL, Cowles MW, Weinzapfel EN, Keogh MC, Burg JM. Nucleosome context regulates chromatin reader preference. Nucleic Acids Res. 2025 Oct 28; 53(20).
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Keogh MC, Almouzni G, Andrews AJ, Armache KJ, Arrowsmith CH, Baek SH, Bedford MT, Bernstein E, Côté J, David Y, Denu JM, Fierz B, Garcia BA, Glass KC, Gozani O, Helin K, Henikoff S, Jensen ON, Josefowicz SZ, Kelleher NL, Kutateladze TG, Lindner HH, Lu C, Luger K, Mallick P, Musselman CA, Muir TW, Pa?a-Tolic L, Schneider R, Shi X, Shi Y, Sidoli S, Smith LM, Tyler JK, Wolberger C, Workman JL, Strahl BD, Young NL. A needed nomenclature for nucleosomes. Mol Cell. 2025 Oct 02; 85(19):3554-3561.
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Villalta A, Bisio H, Toner CM, Abergel C, Luger K. Melbournevirus encodes a shorter H2B-H2A doublet histone variant that forms structurally distinct nucleosome structures. Nat Commun. 2025 Jul 26; 16(1):6903.
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Tonsager AJ, Zukowski A, Radebaugh CA, Weirich A, Stargell LA, Ramachandran S. The histone chaperone Spn1 preserves chromatin protections at promoters and nucleosome positioning in open reading frames. G3 (Bethesda). 2025 04 17; 15(4).
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Vann KR, Sharma R, Hsu CC, Devoucoux M, Tencer AH, Zeng L, Lin K, Zhu L, Li Q, Lachance C, Ospina RR, Tong Q, Cheung KL, Yang S, Biswas S, Xuan H, Gatchalian J, Alamillo L, Wang J, Jang SM, Klein BJ, Lu Y, Ernst P, Strahl BD, Rothbart SB, Walsh MJ, Cleary ML, Côté J, Shi X, Zhou MM, Kutateladze TG. Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation. Nat Commun. 2025 Mar 06; 16(1):2235.
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Toner CM, Hoitsma NM, Weerawarana S, Luger K. Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histone. Nat Commun. 2024 10 23; 15(1):9138.
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Aboulache BL, Hoitsma NM, Luger K. Phosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange. J Biol Chem. 2024 12; 300(12):107893.
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Haase MAB, Lazar-Stefanita L, Ólafsson G, Wudzinska A, Shen MJ, Truong DM, Boeke JD. macroH2A1 drives nucleosome dephasing and genome instability in histone humanized yeast. Cell Rep. 2024 07 23; 43(7):114472.
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Veronezi GMB, Ramachandran S. Nucleation and spreading maintain Polycomb domains every cell cycle. Cell Rep. 2024 04 23; 43(4):114090.
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