Ependymoma
"Ependymoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)
| Descriptor ID |
D004806
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| MeSH Number(s) |
C04.557.465.625.600.380.290 C04.557.470.670.380.290 C04.557.580.625.600.380.290
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| Concept/Terms |
Ependymoma, Papillary- Ependymoma, Papillary
- Ependymomas, Papillary
- Papillary Ependymomas
- Papillary Ependymoma
Ependymoma, Myxopapillary- Ependymoma, Myxopapillary
- Ependymomas, Myxopapillary
- Myxopapillary Ependymoma
- Myxopapillary Ependymomas
Anaplastic Ependymoma- Anaplastic Ependymoma
- Anaplastic Ependymomas
- Ependymoma, Anaplastic
- Ependymomas, Anaplastic
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Below are MeSH descriptors whose meaning is more general than "Ependymoma".
Below are MeSH descriptors whose meaning is more specific than "Ependymoma".
This graph shows the total number of publications written about "Ependymoma" by people in this website by year, and whether "Ependymoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2009 | 3 | 0 | 3 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2015 | 4 | 0 | 4 | | 2016 | 2 | 0 | 2 | | 2017 | 3 | 0 | 3 | | 2018 | 2 | 0 | 2 | | 2019 | 3 | 0 | 3 | | 2020 | 2 | 1 | 3 | | 2021 | 5 | 0 | 5 | | 2022 | 6 | 0 | 6 | | 2023 | 6 | 0 | 6 | | 2024 | 4 | 0 | 4 | | 2025 | 1 | 0 | 1 | | 2026 | 3 | 0 | 3 |
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Below are the most recent publications written about "Ependymoma" by people in Profiles.
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Smith AA, Onar-Thomas A, Lensing S, Dalton J, Bennett J, Tatevossian RG, Bertrand K, Lindsay H, Tabori U, Owens-Pickle E, Blackburn PR, Handler MH, Chambwe N, El Khoury L, Lau C, Kunin-Batson A, Sands S, Wu S, Zhou T, Chang A, Merchant TE, Leary S, Fouladi M, Gajjar A, Pollack IF, Foreman NK, Ellison DW. Phase 3 randomized trial of postirradiation chemotherapy in patients with newly diagnosed ependymoma: A report from the Children's Oncology Group. Neuro Oncol. 2026 May 01; 28(5):1286-1297.
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Kardian AS, Sun H, Ippagunta S, Laboe N, Varadharajan S, Yu K, Chen HC, Emanus E, Zheng T, Deneen RM, Connelly JP, Wang YD, Zhan J, Liu H, Lowe K, Bugbee T, Pathak R, Bland A, Mehta S, Cochiolo S, Arabzade A, Holcomb B, Budd KM, Kembuan G, Wright T, Caesar E, Park M, Hancock A, Gee D, Murdoch J, Xiao Y, McBrayer SK, Merchant TE, Qi J, Durbin AD, Schwarz LA, Wang L, Donson AM, Foreman NK, Agnihotri S, Lavado A, Baker SJ, Ellison DW, Lee HK, Pruett-Miller SM, Bertrand KC, Deneen B, Mack SC. Dominant clones leverage developmental epigenomic states to drive ependymoma. Nature. 2026 04; 652(8111):1027-1037.
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Natarajan SK, Lum J, Skeans JH, Nenwani M, Eyunni S, Mota M, Bayliss JM, Deogharkar A, Hamanishi ET, Pun M, Sweha SR, Hoffman S, Young E, Zhang Q, Mehta R, Animasahun O, Narayanan P, Sunil S, Parolia A, Sajjakulnukit P, Panwalkar P, Doherty R, Clausen M, Dang D, Hawes D, Yang F, Santi M, Judkins AR, Wilson Y, Vigil T, Franson A, Mortensen RM, Ozawa T, Griesinger A, Holland EC, Foreman NK, Michealraj KA, Agnihotri S, Taylor M, Gilbertson RJ, Koschmann C, Chinnaiyan AM, Lyssiotis CA, Nagrath D, Venneti S. ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion expression. Nature. 2026 04; 652(8111):1004-1015.
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de Sousa GR, Calzadilla AJ, Grimaldo E, Donson AM, Sobral LM, Jones KM, Liu T, Amani V, Venkataraman S, Dahl NA, Levy JMM, Phang T, Vibhakar R, Hankinson T, Handler M, Valera ET, Foreman NK, Griesinger AM. Loss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth. Neuro Oncol. 2025 Jul 30; 27(6):1597-1610.
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Mestnik S, Sorajja N, Lu Z, Mills LJ, Williams L. Sex Differences in Ependymoma Methylation by Methylation-Defined Subgroup. J Cell Mol Med. 2024 12; 28(24):e70286.
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Chen HC, He P, McDonald M, Williamson MR, Varadharajan S, Lozzi B, Woo J, Choi DJ, Sardar D, Huang-Hobbs E, Sun H, Ippagunta SM, Jain A, Rao G, Merchant TE, Ellison DW, Noebels JL, Bertrand KC, Mack SC, Deneen B. Histone serotonylation regulates ependymoma tumorigenesis. Nature. 2024 08; 632(8026):903-910.
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Griesinger AM, Calzadilla AJ, Grimaldo E, Donson AM, Amani V, Pierce AM, Steiner J, Kargar S, Serkova NJ, Bertrand KC, Wright KD, Vibhakar R, Hankinson T, Handler M, Lindsay HB, Foreman NK, Dorris K. Development of Chromosome 1q+ Specific Treatment for Highest Risk Pediatric Posterior Fossa Ependymoma. Clin Cancer Res. 2024 Apr 15; 30(8):1544-1554.
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Cheng D, Zhuo Z, Du J, Weng J, Zhang C, Duan Y, Sun T, Wu M, Guo M, Hua T, Jin Y, Peng B, Li Z, Zhu M, Imami M, Bettegowda C, Sair H, Bai HX, Barkhof F, Liu X, Liu Y. A Fully Automated Deep-Learning Model for Predicting the Molecular Subtypes of Posterior Fossa Ependymomas Using T2-Weighted Images. Clin Cancer Res. 2024 01 05; 30(1):150-158.
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Donson AM, Bertrand KC, Riemondy KA, Gao D, Zhuang Y, Sanford B, Norris GA, Chapman RJ, Fu R, Willard N, Griesinger AM, Ribeiro de Sousa G, Amani V, Grimaldo E, Hankinson TC, Booker F, Sill M, Grundy RG, Pajtler KW, Ellison DW, Foreman NK, Ritzmann TA. Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study. Neuro Oncol. 2023 10 03; 25(10):1854-1867.
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Okonechnikov K, Joshi P, Sepp M, Leiss K, Sarropoulos I, Murat F, Sill M, Beck P, Chan KC, Korshunov A, Sah F, Deng MY, Sturm D, DeSisto J, Donson AM, Foreman NK, Green AL, Robinson G, Orr BA, Gao Q, Darrow E, Hadley JL, Northcott PA, Gojo J, Kawauchi D, Hovestadt V, Filbin MG, von Deimling A, Zuckermann M, Pajtler KW, Kool M, Jones DTW, Jäger N, Kutscher LM, Kaessmann H, Pfister SM. Mapping pediatric brain tumors to their origins in the developing cerebellum. Neuro Oncol. 2023 10 03; 25(10):1895-1909.
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