 Ligands
"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
| Descriptor ID |
D008024
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| MeSH Number(s) |
D27.720.470.480
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ligands".
Below are MeSH descriptors whose meaning is more specific than "Ligands".
This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 8 | 8 | | 1996 | 0 | 12 | 12 | | 1997 | 0 | 3 | 3 | | 1998 | 1 | 9 | 10 | | 1999 | 0 | 8 | 8 | | 2000 | 0 | 10 | 10 | | 2001 | 0 | 9 | 9 | | 2002 | 0 | 10 | 10 | | 2003 | 0 | 24 | 24 | | 2004 | 0 | 16 | 16 | | 2005 | 0 | 18 | 18 | | 2006 | 1 | 21 | 22 | | 2007 | 0 | 14 | 14 | | 2008 | 0 | 18 | 18 | | 2009 | 2 | 20 | 22 | | 2010 | 0 | 14 | 14 | | 2011 | 2 | 12 | 14 | | 2012 | 1 | 15 | 16 | | 2013 | 1 | 14 | 15 | | 2014 | 0 | 14 | 14 | | 2015 | 1 | 11 | 12 | | 2016 | 2 | 12 | 14 | | 2017 | 1 | 8 | 9 | | 2018 | 0 | 11 | 11 | | 2019 | 1 | 8 | 9 | | 2020 | 1 | 19 | 20 | | 2021 | 0 | 11 | 11 | | 2022 | 0 | 24 | 24 | | 2023 | 0 | 21 | 21 | | 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ligands" by people in Profiles.
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Mishra N, Kant R, Kandhari K, Ammar DA, Tewari-Singh N, Pantcheva MB, Petrash JM, Agarwal C, Agarwal R. Nitrogen Mustard-Induced Ex Vivo Human Cornea Injury Model and Therapeutic Intervention by Dexamethasone. J Pharmacol Exp Ther. 2024 01 17; 388(2):484-494.
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Sottnik JL, Shackleford MT, Robinson SK, Villagomez FR, Bahnassy S, Oesterreich S, Hu J, Madak-Erdogan Z, Riggins RB, Corr BR, Cook LS, Trevi?o LS, Bitler BG, Sikora MJ. WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers. Cancer Res Commun. 2024 01 17; 4(1):134-151.
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Park SY, Qiu J, Wei S, Peterson FC, Beltr?n J, Medina-Cucurella AV, Vaidya AS, Xing Z, Volkman BF, Nusinow DA, Whitehead TA, Wheeldon I, Cutler SR. An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity. Nat Chem Biol. 2024 Jan; 20(1):103-110.
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Tsai PS, Sanders KN, Dai X, Plachetzki D. Authentication of a lophotrochozoan adipokinetic hormone receptor in a Gastropod, Aplysia californica. Gen Comp Endocrinol. 2024 01 01; 345:114393.
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Mikosz A, Ni K, Gally F, Pratte KA, Winfree S, Lin Q, Echelman I, Wetmore B, Cao D, Justice MJ, Sandhaus RA, Maier L, Strange C, Bowler RP, Petrache I, Serban KA. Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions. Am J Physiol Lung Cell Mol Physiol. 2023 12 01; 325(6):L711-L725.
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Epeldegui M, Chang D, Lee J, Magpantay LI, Borok M, Bukuru A, Busakhala N, Godfrey C, Hosseinipour MC, Kang M, Kanyama C, Langat D, Mngqibisa R, Mwelase N, Nyirenda M, Samaneka W, Hoagland B, Campbell TB, Mart?nez-Maza O, Krown SE. Predictive Value of Serum Biomarkers for Response of Limited-Stage AIDS-Associated Kaposi Sarcoma to Antiretroviral Therapy With or Without Concomitant Chemotherapy in Resource-Limited Settings. J Acquir Immune Defic Syndr. 2023 10 01; 94(2):165-173.
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Amani V, Riemondy KA, Fu R, Griesinger AM, Grimaldo E, De Sousa GR, Gilani A, Hemenway M, Foreman NK, Donson AM, Willard N. Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas. Acta Neuropathol Commun. 2023 09 28; 11(1):158.
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Burris TP, de Vera IMS, Cote I, Flaveny CA, Wanninayake US, Chatterjee A, Walker JK, Steinauer N, Zhang J, Coons LA, Korach KS, Cain DW, Hollenberg AN, Webb P, Forrest D, Jetten AM, Edwards DP, Grimm SL, Hartig S, Lange CA, Richer JK, Sartorius CA, Tetel M, Billon C, Elgendy B, Hegazy L, Griffett K, Peinetti N, Burnstein KL, Hughes TS, Sitaula S, Stayrook KR, Culver A, Murray MH, Finck BN, Cidlowski JA. International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023. Pharmacol Rev. 2023 Nov; 75(6):1233-1318.
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Staquicini DI, Card?-Vila M, Rotolo JA, Staquicini FI, Tang FHF, Smith TL, Ganju A, Schiavone C, Dogra P, Wang Z, Cristini V, Giordano RJ, Ozawa MG, Driessen WHP, Proneth B, Souza GR, Brinker LM, Noureddine A, Snider AJ, Canals D, Gelovani JG, Petrache I, Tuder RM, Obeid LM, Hannun YA, Kolesnick RN, Brinker CJ, Pasqualini R, Arap W. Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands. Proc Natl Acad Sci U S A. 2023 08 22; 120(34):e2220269120.
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Walrath T, Najarro KM, Giesy LE, Khair S, Frank DN, Robertson CE, Orlicky DJ, Quillinan N, Idrovo JP, McMahan RH, Kovacs EJ. REMOTE BURN INJURY IN AGED MICE INDUCES COLONIC LYMPHOID AGGREGATE EXPANSION AND DYSBIOSIS OF THE FECAL MICROBIOME WHICH CORRELATES WITH NEUROINFLAMMATION. Shock. 2023 10 01; 60(4):585-593.
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