DNA Repair
"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
Descriptor ID |
D004260
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MeSH Number(s) |
G02.111.222 G05.219
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Concept/Terms |
Base Excision Repair- Base Excision Repair
- Base Excision Repairs
- Excision Repair, Base
- Repair, Base Excision
- Repairs, Base Excision
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Below are MeSH descriptors whose meaning is more general than "DNA Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Repair".
This graph shows the total number of publications written about "DNA Repair" by people in this website by year, and whether "DNA Repair" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 1998 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2000 | 2 | 3 | 5 | 2001 | 1 | 0 | 1 | 2002 | 0 | 2 | 2 | 2003 | 2 | 0 | 2 | 2004 | 5 | 3 | 8 | 2005 | 2 | 1 | 3 | 2006 | 2 | 6 | 8 | 2007 | 3 | 4 | 7 | 2008 | 5 | 2 | 7 | 2009 | 3 | 1 | 4 | 2010 | 2 | 4 | 6 | 2011 | 3 | 3 | 6 | 2012 | 1 | 3 | 4 | 2013 | 2 | 4 | 6 | 2014 | 2 | 6 | 8 | 2015 | 6 | 5 | 11 | 2016 | 2 | 6 | 8 | 2017 | 1 | 6 | 7 | 2018 | 4 | 5 | 9 | 2019 | 3 | 5 | 8 | 2020 | 4 | 3 | 7 | 2021 | 3 | 2 | 5 | 2022 | 3 | 6 | 9 | 2023 | 3 | 2 | 5 | 2024 | 1 | 3 | 4 | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Repair" by people in Profiles.
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Jalan M, Brambati A, Shah H, McDermott N, Patel J, Zhu Y, Doymaz A, Wu J, Anderson KS, Gazzo A, Pareja F, Yamaguchi TN, Vougiouklakis T, Ahmed-Seghir S, Steinberg P, Neiman-Golden A, Azeroglu B, Gomez-Aguilar J, da Silva EM, Hussain S, Higginson D, Boutros PC, Riaz N, Reis-Filho JS, Powell SN, Sfeir A. RNA transcripts serve as a template for double-strand break repair in human cells. Nat Commun. 2025 May 10; 16(1):4349.
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Yokoyama A, Niida H, Kutateladze TG, C?t? J. HBO1, a MYSTerious KAT and its links to cancer. Biochim Biophys Acta Gene Regul Mech. 2024 Sep; 1867(3):195045.
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Walker FM, Sobral LM, Danis E, Sanford B, Donthula S, Balakrishnan I, Wang D, Pierce A, Karam SD, Kargar S, Serkova NJ, Foreman NK, Venkataraman S, Dowell R, Vibhakar R, Dahl NA. Rapid P-TEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy. Nat Commun. 2024 May 30; 15(1):4616.
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Arnoult N, Cech TR. Telomerase misbehaves after a breakup. Science. 2024 02 16; 383(6684):702-703.
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Affandi T, Haas A, Ohm AM, Wright GM, Black JC, Reyland ME. PKCd Regulates Chromatin Remodeling and DNA Repair through SIRT6. Mol Cancer Res. 2024 02 01; 22(2):181-196.
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Stojanovic P, Luger K, Rudolph J. Slow Dissociation from the PARP1-HPF1 Complex Drives Inhibitor Potency. Biochemistry. 2023 08 15; 62(16):2382-2390.
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Ngo K, Gittens TH, Gonzalez DI, Hatmaker EA, Plotkin S, Engle M, Friedman GA, Goldin M, Hoerr RE, Eichman BF, Rokas A, Benton ML, Friedman KL. A comprehensive map of hotspots of de novo telomere addition in Saccharomyces cerevisiae. Genetics. 2023 05 26; 224(2).
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Arnoult N. Meet the authors: Nausica Arnoult. Mol Cell. 2023 05 04; 83(9):1369-1371.
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Rudolph J, Luger K. PARP1 and HPF1 team up to flag down DNA-repair machinery. Nat Struct Mol Biol. 2023 05; 30(5):568-569.
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Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcal? K, Ball K, Proctor B, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining. Mol Cell. 2023 05 04; 83(9):1429-1445.e8.
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