Tumor Microenvironment
"Tumor Microenvironment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The milieu surrounding neoplasms consisting of cells, vessels, soluble factors, and molecules, that can influence and be influenced by, the neoplasm's growth.
| Descriptor ID |
D059016
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| MeSH Number(s) |
G04.366.500
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| Concept/Terms |
Tumor Microenvironment- Tumor Microenvironment
- Microenvironment, Tumor
- Microenvironments, Tumor
- Tumor Microenvironments
Cancer Microenvironment- Cancer Microenvironment
- Cancer Microenvironments
- Microenvironment, Cancer
- Microenvironments, Cancer
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Below are MeSH descriptors whose meaning is more general than "Tumor Microenvironment".
Below are MeSH descriptors whose meaning is more specific than "Tumor Microenvironment".
This graph shows the total number of publications written about "Tumor Microenvironment" by people in this website by year, and whether "Tumor Microenvironment" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 2 | 1 | 3 | | 2013 | 2 | 7 | 9 | | 2014 | 1 | 3 | 4 | | 2015 | 7 | 2 | 9 | | 2016 | 8 | 8 | 16 | | 2017 | 2 | 17 | 19 | | 2018 | 7 | 12 | 19 | | 2019 | 16 | 21 | 37 | | 2020 | 14 | 30 | 44 | | 2021 | 7 | 38 | 45 | | 2022 | 1 | 44 | 45 | | 2023 | 4 | 41 | 45 | | 2024 | 16 | 38 | 54 | | 2025 | 13 | 28 | 41 | | 2026 | 3 | 5 | 8 |
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Below are the most recent publications written about "Tumor Microenvironment" by people in Profiles.
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Duval H, Toomey B, Karam M, Braun T, Fournier D, Grant C, Fairfield H, Chepurko V, Chepurko E, Schimelman A, Nestor B, Ryzhov S, Lindner V, Reagan MR. Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer. Oncotarget. 2026 May 20; 17(1):258-267.
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Ahmed M, Haneefa SM, Alam A, Kali SK, Al-Sbiei A, Bashir G, Al-Bawardi A, Idriss I, Mohamed YA, Khlaifat B, Naser HT, Labania L, Hamoudi R, Kishore U, Attoub S, Rincon M, Ramadi KB, Fernandez-Cabezudo MJ, Al-Ramadi BK. Modulation of the immunogenic landscape in colorectal cancer by mitochondrial methylation-controlled J protein. Mol Biomed. 2026 May 11; 7(1).
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Lee J, Chung YM, Silver DJ, Hao Y, Harwood DSL, Ealy A, Serapiglia AM, Curtin L, Benedetti JR, Ballard CAP, Lapsley K, Alvarez-Vazquez A, Goldberg J, Li C, Kaur S, Neal R, Wang SZ, Kay KE, Volovetz J, Hong ES, Fodor R, Jarmula J, Nicosia M, Rubin JB, Swanson KR, Ostrom QT, Panicker N, Kristensen BW, Berens M, Sharifi N, Lathia JD. Androgen loss accelerates brain tumour growth via HPA axis activation. Nature. 2026 May; 653(8116):1184-1195.
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Shen S, Mohan AA, Hotchkiss KM, Cook S, Patel K, Moelker E, Puviindran B, Gonzalez AT, Zaidi S, Spellicy S, Schwartz A, Suryadevara C, Wilkinson D, Ayasoufi K, Fecci PE, Sanchez-Perez L, Sampson J, Patel A. IL-12-secreting CAR-T cells reprogram the tumor microenvironment and improve efficacy against heterogeneous models of glioblastoma. J Immunother Cancer. 2026 Mar 24; 14(3).
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Christenson JL, Spoelstra NS, Williams MM, Logan LL, O'Neill KI, Orlicky DJ, Baker NT, Wagner JA, Staley AW, Van Bokhoven A, Goodspeed A, Kuo LW, Crump LS, Diamond JR, Richer JK. Metastasis-Associated Wound Repair Promotes Reciprocal Lung Epithelium Activation and Breast Cancer Metastatic Outgrowth. Cancer Res Commun. 2026 04 01; 6(4):750-768.
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Ohlstrom DJ, Pilcher WC, Michaud ME, Acharya C, Satpathy S, Gonzalez-Kozlova E, Jayasinghe RG, Ferguson K, Mumme HL, Nanda S, Song Y, Mantrala S, Karagkouni D, Schulman J, Pabustan N, Vieira Dos Santos J, Sherbenou DW, Keats JJ, Gout AM, Foltz S, Lagana A, Kourelis T, Vij R, Dhodapkar MV, Avigan D, Cho HJ, Baughn LB, Nooka AK, Lonial S, Kumar S, Samur MK, Vlachos IS, Ding L, Gnjatic S, Mulligan G, Bhasin MK. Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma. Blood Cancer Discov. 2026 Mar 04; 7(2):266-286.
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Tomar MS, Raina K, Mishra N, Kant R, Fox JT, Agarwal C, Agarwal R. Distinct Tumor Infiltrating Immune Cell Profiles in Mice by Non-Steroidal Anti-Inflammatory Drugs (Aspirin and Naproxen) During TMPRSS2-ERG (Fusion)-Driven and Non-Fusion Driven Prostate Cancer. Mol Carcinog. 2026 May; 65(5):589-602.
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Sakitis CJ, Laborde J, Wrobel J, Soupir AC, Colin-Leitzinger CM, Bitler BG, Townsend MK, Lawson AB, Schildkraut JM, Tworoger SS, Terry KL, Peres LC, Fridley BL. Bayesian multi-cell type models for the analysis of complex immune cell populations with application to ovarian cancer. Brief Bioinform. 2026 Jan 07; 27(1).
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Prawira A, Xu H, Mei Y, Leow WQ, Nasir NJM, Reolo MJ, Otsuka M, Rahbari M, Chen Z, Weerasooriya M, Abdullah LB, Wu J, Hazirah SN, Wasser M, Chung A, Goh BK, Chow PK, Albani S, Lee J, Lim TKH, Zhai W, Dan YY, Goh GB, Heikenwälder MF, Zhang Y, Dasgupta R, Tai WMD, Liu H, Chen J, Chew V. Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma. Gut. 2025 Dec 05; 75(1):105-118.
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Ajaib S, Winter-Luke J, Digby RJ, Pollock S, Hemmings G, Gusnanto A, Chakrabarty A, Ismail A, Wilson E, Hunter B, Filby A, McDonald D, Brockman AA, Ihrie RA, Stead LF. Spatial profiling of longitudinal glioblastoma reveals consistent changes in cellular architecture, post-treatment. Neuro Oncol. 2025 Dec 01; 27(12):3145-3160.
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