 Tumor Microenvironment
"Tumor Microenvironment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The milieu surrounding neoplasms consisting of cells, vessels, soluble factors, and molecules, that can influence and be influenced by, the neoplasm's growth.
| Descriptor ID |
D059016
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| MeSH Number(s) |
G04.366.500
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| Concept/Terms |
Tumor Microenvironment- Tumor Microenvironment
- Microenvironment, Tumor
- Microenvironments, Tumor
- Tumor Microenvironments
Cancer Microenvironment- Cancer Microenvironment
- Cancer Microenvironments
- Microenvironment, Cancer
- Microenvironments, Cancer
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Below are MeSH descriptors whose meaning is more general than "Tumor Microenvironment".
Below are MeSH descriptors whose meaning is more specific than "Tumor Microenvironment".
This graph shows the total number of publications written about "Tumor Microenvironment" by people in this website by year, and whether "Tumor Microenvironment" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 2 | 7 | 9 | | 2014 | 0 | 3 | 3 | | 2015 | 7 | 3 | 10 | | 2016 | 8 | 6 | 14 | | 2017 | 3 | 16 | 19 | | 2018 | 7 | 13 | 20 | | 2019 | 15 | 21 | 36 | | 2020 | 14 | 30 | 44 | | 2021 | 7 | 37 | 44 | | 2022 | 1 | 43 | 44 | | 2023 | 4 | 42 | 46 | | 2024 | 15 | 37 | 52 | | 2025 | 13 | 28 | 41 | | 2026 | 6 | 10 | 16 |
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Below are the most recent publications written about "Tumor Microenvironment" by people in Profiles.
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Kane GI, Diaz-Infante MB, Wigglesworth K, Lusi E, Brassil M, Rozen EJ, Kady J, Mori H, Lukas J, Naylor T, Dinnell RW, Murphy KC, Alarcon CBB, Ruscetti M, Brehm M, Shohet JM, Atukorale PU. Tumor Homing Nanoparticle Immunotherapy for Acute Clearance and Mitigation of T-cell Exhaustion in Humanized High-Risk Neuroblastoma. Mol Cancer Ther. 2026 Jul 02; 25(7):1144-1156.
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Fukuda R, Fujiwara Y, Maruyama T, Komohara Y. CD169-positive macrophages in lymph nodes and the tumor microenvironment: harnessing their biology for clinical diagnosis and anticancer therapeutic strategies. Front Immunol. 2026; 17:1852700.
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Liu Y, Carter JM, Ma Y, Deshmukh SK, Sledge GW, Balko JM, Kachergus JM, Shi J, Gregory M, Gong J, Joensuu H, Perez EA, Stover D, Carey L, Sikov WM, Leon-Ferre R, Knutson KL, Boughey JC, Ingle JN, Kalari KR, Couch FJ, Asmann YW, Goetz MP, Thompson EA, Chumsri S. Spatially resolved single-cell landscape of tumor immunotypes reveals the central role of interferon signaling and plasmacytoid dendritic cells in triple-negative breast cancer. J Immunother Cancer. 2026 Jun 03; 14(6).
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Tesch ME, Zheng Y, Guzman-Arocho YD, Collins LC, Heng YJ, Tayob N, Rosenberg SM, Ruddy KJ, Tamimi RM, Schapira L, Peppercorn J, Borges V, Come SE, Snow C, Winer EP, Mittendorf EA, Partridge AH. Association of Tumor-Infiltrating Lymphocyte Subtypes with Clinical Characteristics and Prognosis in Young Women with Hormone Receptor-Positive Breast Cancer. Clin Cancer Res. 2026 Jun 01; 32(11):2268-2278.
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Chakravorty S, Zybina Y, Ahn E, Pradhan K, Yu N, Taylor M, Charati M, Wilson DC, Jeon AB, Blumenschein WM, Han JH. Immune Reprogramming of Tumor Microenvironments by Cytotoxic Antibody-Drug Conjugate Payloads. Mol Cancer Ther. 2026 Jun 01; 25(6):976-991.
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Aleman JD, Young CD, Ke Y, Nguyen KA, Lu I, Goon JB, Abello AE, Lind HT, Karam SD, Birkeland AC, Wang XJ. Ectopic integrin ß1 overproduction by squamous carcinoma cells contributes to immune evasion-associated metastasis. Cancer Lett. 2026 Sep 28; 656:218635.
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Duval H, Toomey B, Karam M, Braun T, Fournier D, Grant C, Fairfield H, Chepurko V, Chepurko E, Schimelman A, Nestor B, Ryzhov S, Lindner V, Reagan MR. Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer. Oncotarget. 2026 May 20; 17(1):258-267.
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Ahmed M, Haneefa SM, Alam A, Kali SK, Al-Sbiei A, Bashir G, Al-Bawardi A, Idriss I, Mohamed YA, Khlaifat B, Naser HT, Labania L, Hamoudi R, Kishore U, Attoub S, Rincon M, Ramadi KB, Fernandez-Cabezudo MJ, Al-Ramadi BK. Modulation of the immunogenic landscape in colorectal cancer by mitochondrial methylation-controlled J protein. Mol Biomed. 2026 May 11; 7(1).
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Williams MM, Christenson JL, Spoelstra NS, Hafeez SA, Kuo LW, Crump LS, O'Neill KI, Hill AA, Phan A, McCue LM, Hintelmann TM, Ruiz J, Sax HE, Williams J, Boorgula MP, Goodspeed A, Slansky JE, Richer JK. Aggressive breast cancers secrete heme metabolites to alter macrophage immune suppression and function. Commun Biol. 2026 May 09; 9(1).
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Lee J, Chung YM, Silver DJ, Hao Y, Harwood DSL, Ealy A, Serapiglia AM, Curtin L, Benedetti JR, Ballard CAP, Lapsley K, Alvarez-Vazquez A, Goldberg J, Li C, Kaur S, Neal R, Wang SZ, Kay KE, Volovetz J, Hong ES, Fodor R, Jarmula J, Nicosia M, Rubin JB, Swanson KR, Ostrom QT, Panicker N, Kristensen BW, Berens M, Sharifi N, Lathia JD. Androgen loss accelerates brain tumour growth via HPA axis activation. Nature. 2026 May; 653(8116):1184-1195.
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