 Tumor Microenvironment
"Tumor Microenvironment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The milieu surrounding neoplasms consisting of cells, vessels, soluble factors, and molecules, that can influence and be influenced by, the neoplasm's growth.
| Descriptor ID |
D059016
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| MeSH Number(s) |
G04.366.500
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| Concept/Terms |
Tumor Microenvironment- Tumor Microenvironment
- Microenvironment, Tumor
- Microenvironments, Tumor
- Tumor Microenvironments
Cancer Microenvironment- Cancer Microenvironment
- Cancer Microenvironments
- Microenvironment, Cancer
- Microenvironments, Cancer
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Below are MeSH descriptors whose meaning is more general than "Tumor Microenvironment".
Below are MeSH descriptors whose meaning is more specific than "Tumor Microenvironment".
This graph shows the total number of publications written about "Tumor Microenvironment" by people in this website by year, and whether "Tumor Microenvironment" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 2 | 7 | 9 | | 2014 | 1 | 3 | 4 | | 2015 | 7 | 2 | 9 | | 2016 | 8 | 6 | 14 | | 2017 | 2 | 15 | 17 | | 2018 | 7 | 13 | 20 | | 2019 | 15 | 21 | 36 | | 2020 | 14 | 28 | 42 | | 2021 | 6 | 36 | 42 | | 2022 | 2 | 43 | 45 | | 2023 | 2 | 39 | 41 | | 2024 | 14 | 37 | 51 | | 2025 | 12 | 29 | 41 |
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Below are the most recent publications written about "Tumor Microenvironment" by people in Profiles.
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Prawira A, Xu H, Mei Y, Leow WQ, Nasir NJM, Reolo MJ, Otsuka M, Rahbari M, Chen Z, Weerasooriya M, Abdullah LB, Wu J, Hazirah SN, Wasser M, Chung A, Goh BK, Chow PK, Albani S, Lee J, Lim TKH, Zhai W, Dan YY, Goh GB, Heikenwälder MF, Zhang Y, Dasgupta R, Tai WMD, Liu H, Chen J, Chew V. Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma. Gut. 2025 Dec 05; 75(1):105-118.
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Ajaib S, Winter-Luke J, Digby RJ, Pollock S, Hemmings G, Gusnanto A, Chakrabarty A, Ismail A, Wilson E, Hunter B, Filby A, McDonald D, Brockman AA, Ihrie RA, Stead LF. Spatial profiling of longitudinal glioblastoma reveals consistent changes in cellular architecture, post-treatment. Neuro Oncol. 2025 Dec 01; 27(12):3145-3160.
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Kuo C, Giannikou K, Wang N, Warren M, Goodspeed A, Shillingford N, Hayashi M, Raredon MSB, Amatruda JF. Spatial Profiling Identifies Tumor-Associated Stroma Enrichment and MIF as Potential Immunotherapy Targets in Primary Ewing Sarcomas. Clin Cancer Res. 2025 Dec 01; 31(23):5051-5069.
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Geng D, Chen J, Sanchez A, Davalos SA, Wilcox P, Gonzales-Rivera D, Couts K, Tobin R, Robinson W, Nielsen AJ, Guo J, McCarter M, Crump L, Tsujimoto K, Wilky BA, Davila E. Melanoma leverages innate immune IRAK-M signaling to limit metastasis through PTPN22-Induced signaling repression. Cancer Lett. 2026 Feb 28; 639:218172.
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Klosowski ML, Cronise KE, Palmer EP, McAuliffe K, Stratton C, Sparks K, Malmstrom KT, Knott-Byars G, Zhou Q, Esquer H, LaBarbera DV, Regan DP. Breast cancer cell coculture induces normal lung fibroblast transition to CAFs, promoting tumor cell dormancy and therapy resistance. Proc Natl Acad Sci U S A. 2025 Nov 25; 122(47):e2423894122.
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Fujiwara Y, Komohara Y. Therapeutic Strategies Targeting CD163 and CD169 in Macrophages for Cancer. Pathol Int. 2025 Nov; 75(11):551-561.
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Bitler BG, Lang J, Nunez-Avellaneda D, Behbakht K, Davidson NR, Woodruff ER, Villagomez FR. Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer. Sci Rep. 2025 Nov 10; 15(1):39257.
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Sharma S, Ali R, Bouska A, Jochum D, Kesireddy M, Mahov S, Lownik J, Zhang W, Lone W, Soma MA, Gamboa A, Devarakonda V, El-Gamal D, Fariha A, Mansoor A, Stewart D, Martin P, Link BK, Advani RH, Barr PM, Goy AH, Mehta A, Kamdar M, Stephens DM, Bachanova V, Smith L, Morin R, Pararajalingam P, Lunning MA, Fu K, Weisenburger D, Chan WC, Khoury J, Greiner TC, Vose JM, Merchant A, Bi C, Iqbal J. Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma. Nat Commun. 2025 Nov 05; 16(1):9762.
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Henrich IC, Billingsley MM, Jain K, Mondal S, Quick LN, Young R, Nguyen N, Oliveira AM, Blobel GA, Mitchell MJ, Chou MM. Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma. Mol Cancer Ther. 2025 Nov 03; 24(11):1802-1814.
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Wang J, Huang X, Shi Q, Swingle KL, Hamilton AG, Gong N, Mitchell MJ. Drug-loaded bispecific T cell nanoengager overcomes T cell exhaustion for potent cancer immunotherapy. Proc Natl Acad Sci U S A. 2025 Nov 11; 122(45):e2409564122.
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