 Electron Transport Complex II
"Electron Transport Complex II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein oxidase complex that contains iron-sulfur centers. It catalyzes the oxidation of SUCCINATE to fumarate and couples the reaction to the reduction of UBIQUINONE to ubiquinol.
| Descriptor ID |
D042963
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| MeSH Number(s) |
D05.500.562.750.249 D08.811.600.250.500.750 D08.811.600.250.875.249 D08.811.682.660.385 D08.811.682.830.249 D12.776.157.427.374.375.909 D12.776.331.199.750 D12.776.543.277.500.750 D12.776.543.277.875.249 D12.776.556.579.374.375.141
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| Concept/Terms |
Electron Transport Complex II- Electron Transport Complex II
- Succinate-Ubiquinone Oxidoreductase
- Oxidoreductase, Succinate-Ubiquinone
- Succinate Ubiquinone Oxidoreductase
- Succinate-Ubiquinone Reductase
- Succinate Ubiquinone Reductase
- Succinate-Q Oxidoreductase
- Oxidoreductase, Succinate-Q
- Succinate Q Oxidoreductase
- Succinate Dehydrogenase-Coenzyme Q Reductase
- Succinate Dehydrogenase Coenzyme Q Reductase
- Succinate Dehydrogenase-CoQ Reductase
- Dehydrogenase-CoQ Reductase, Succinate
- Reductase, Succinate Dehydrogenase-CoQ
- Succinate Dehydrogenase CoQ Reductase
- Succinate-Coenzyme Q Reductase
- Succinate Coenzyme Q Reductase
- Succinate-Quinone Oxidoreductase
- Oxidoreductase, Succinate-Quinone
- Succinate Quinone Oxidoreductase
- Succinate Dehydrogenase (Ubiquinone)
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Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex II".
Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex II".
This graph shows the total number of publications written about "Electron Transport Complex II" by people in this website by year, and whether "Electron Transport Complex II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Electron Transport Complex II" by people in Profiles.
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Marumo T, Maduka CV, Ural E, Apu EH, Chung SJ, Tanabe K, van den Berg NS, Zhou Q, Martin BA, Miura T, Rosenthal EL, Shibahara T, Contag CH. Flavinated SDHA underlies the change in intrinsic optical properties of oral cancers. Commun Biol. 2023 11 09; 6(1):1134.
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Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Manipulating mitochondrial electron flow enhances tumor immunogenicity. Science. 2023 09 22; 381(6664):1316-1323.
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Sturrock BRH, Macnamara EF, McGuire P, Kruk S, Yang I, Murphy J, Tifft CJ, Gordon-Lipkin E. Progressive cerebellar atrophy in a patient with complex II and III deficiency and a novel deleterious variant in SDHA: A Counseling Conundrum. Mol Genet Genomic Med. 2021 06; 9(6):e1692.
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Jones CL, Stevens BM, D'Alessandro A, Culp-Hill R, Reisz JA, Pei S, Gustafson A, Khan N, DeGregori J, Pollyea DA, Jordan CT. Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II. Blood. 2019 07 25; 134(4):389-394.
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Pollyea DA, Stevens BM, Jones CL, Winters A, Pei S, Minhajuddin M, D'Alessandro A, Culp-Hill R, Riemondy KA, Gillen AE, Hesselberth JR, Abbott D, Schatz D, Gutman JA, Purev E, Smith C, Jordan CT. Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia. Nat Med. 2018 12; 24(12):1859-1866.
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Fishbein L, Nathanson KL. Pheochromocytoma and Paraganglioma Susceptibility Genes: Estimating the Associated Risk of Disease. JAMA Oncol. 2017 09 01; 3(9):1212-1213.
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Zhang C, Liu Z, Bunker E, Ramirez A, Lee S, Peng Y, Tan AC, Eckhardt SG, Chapnick DA, Liu X. Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response. J Biol Chem. 2017 09 08; 292(36):15105-15120.
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Christensen PM, Jacobs RA, Bonne T, Flück D, Bangsbo J, Lundby C. A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985). 2016 Jun 01; 120(11):1319-27.
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Gifford JR, Trinity JD, Layec G, Garten RS, Park SY, Rossman MJ, Larsen S, Dela F, Richardson RS. Quadriceps exercise intolerance in patients with chronic obstructive pulmonary disease: the potential role of altered skeletal muscle mitochondrial respiration. J Appl Physiol (1985). 2015 Oct 15; 119(8):882-8.
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Boyle KE, Newsom SA, Janssen RC, Lappas M, Friedman JE. Skeletal muscle MnSOD, mitochondrial complex II, and SIRT3 enzyme activities are decreased in maternal obesity during human pregnancy and gestational diabetes mellitus. J Clin Endocrinol Metab. 2013 Oct; 98(10):E1601-9.
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