 Electron Transport Complex II
"Electron Transport Complex II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein oxidase complex that contains iron-sulfur centers. It catalyzes the oxidation of SUCCINATE to fumarate and couples the reaction to the reduction of UBIQUINONE to ubiquinol.
| Descriptor ID |
D042963
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| MeSH Number(s) |
D05.500.562.750.249 D08.811.600.250.500.750 D08.811.600.250.875.249 D08.811.682.660.385 D08.811.682.830.249 D12.776.157.427.374.375.909 D12.776.331.199.750 D12.776.543.277.500.750 D12.776.543.277.875.249 D12.776.556.579.374.375.141
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| Concept/Terms |
Electron Transport Complex II- Electron Transport Complex II
- Succinate-Ubiquinone Oxidoreductase
- Oxidoreductase, Succinate-Ubiquinone
- Succinate Ubiquinone Oxidoreductase
- Succinate-Ubiquinone Reductase
- Succinate Ubiquinone Reductase
- Succinate-Q Oxidoreductase
- Oxidoreductase, Succinate-Q
- Succinate Q Oxidoreductase
- Succinate Dehydrogenase-Coenzyme Q Reductase
- Succinate Dehydrogenase Coenzyme Q Reductase
- Succinate Dehydrogenase-CoQ Reductase
- Dehydrogenase-CoQ Reductase, Succinate
- Reductase, Succinate Dehydrogenase-CoQ
- Succinate Dehydrogenase CoQ Reductase
- Succinate-Coenzyme Q Reductase
- Succinate Coenzyme Q Reductase
- Succinate-Quinone Oxidoreductase
- Oxidoreductase, Succinate-Quinone
- Succinate Quinone Oxidoreductase
- Succinate Dehydrogenase (Ubiquinone)
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Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex II".
Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex II".
This graph shows the total number of publications written about "Electron Transport Complex II" by people in this website by year, and whether "Electron Transport Complex II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Electron Transport Complex II" by people in Profiles.
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Sturrock BRH, Macnamara EF, McGuire P, Kruk S, Yang I, Murphy J, Tifft CJ, Gordon-Lipkin E. Progressive cerebellar atrophy in a patient with complex II and III deficiency and a novel deleterious variant in SDHA: A Counseling Conundrum. Mol Genet Genomic Med. 2021 06; 9(6):e1692.
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Jones CL, Stevens BM, D'Alessandro A, Culp-Hill R, Reisz JA, Pei S, Gustafson A, Khan N, DeGregori J, Pollyea DA, Jordan CT. Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II. Blood. 2019 07 25; 134(4):389-394.
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Pollyea DA, Stevens BM, Jones CL, Winters A, Pei S, Minhajuddin M, D'Alessandro A, Culp-Hill R, Riemondy KA, Gillen AE, Hesselberth JR, Abbott D, Schatz D, Gutman JA, Purev E, Smith C, Jordan CT. Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia. Nat Med. 2018 12; 24(12):1859-1866.
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Fishbein L, Nathanson KL. Pheochromocytoma and Paraganglioma Susceptibility Genes: Estimating the Associated Risk of Disease. JAMA Oncol. 2017 09 01; 3(9):1212-1213.
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Zhang C, Liu Z, Bunker E, Ramirez A, Lee S, Peng Y, Tan AC, Eckhardt SG, Chapnick DA, Liu X. Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response. J Biol Chem. 2017 09 08; 292(36):15105-15120.
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Gifford JR, Trinity JD, Layec G, Garten RS, Park SY, Rossman MJ, Larsen S, Dela F, Richardson RS. Quadriceps exercise intolerance in patients with chronic obstructive pulmonary disease: the potential role of altered skeletal muscle mitochondrial respiration. J Appl Physiol (1985). 2015 Oct 15; 119(8):882-8.
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Boyle KE, Newsom SA, Janssen RC, Lappas M, Friedman JE. Skeletal muscle MnSOD, mitochondrial complex II, and SIRT3 enzyme activities are decreased in maternal obesity during human pregnancy and gestational diabetes mellitus. J Clin Endocrinol Metab. 2013 Oct; 98(10):E1601-9.
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De Paepe B, Vandemeulebroecke K, Smet J, Vanlander A, Seneca S, Lissens W, Van Hove JL, Deschepper E, Briones P, Van Coster R. Effect of resveratrol on cultured skin fibroblasts from patients with oxidative phosphorylation defects. Phytother Res. 2014 Feb; 28(2):312-6.
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Saini-Chohan HK, Dakshinamurti S, Taylor WA, Shen GX, Murphy R, Sparagna GC, Hatch GM. Persistent pulmonary hypertension results in reduced tetralinoleoyl-cardiolipin and mitochondrial complex II + III during the development of right ventricular hypertrophy in the neonatal pig heart. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1415-24.
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Pearce LL, Martinez-Bosch S, Manzano EL, Winnica DE, Epperly MW, Peterson J. The resistance of electron-transport chain Fe-S clusters to oxidative damage during the reaction of peroxynitrite with mitochondrial complex II and rat-heart pericardium. Nitric Oxide. 2009 May; 20(3):135-42.
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