Lipopolysaccharides
"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
| Descriptor ID |
D008070
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| MeSH Number(s) |
D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".
Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".
This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 6 | 10 | 16 | | 1997 | 4 | 7 | 11 | | 1998 | 4 | 9 | 13 | | 1999 | 4 | 10 | 14 | | 2000 | 4 | 12 | 16 | | 2001 | 11 | 17 | 28 | | 2002 | 13 | 21 | 34 | | 2003 | 8 | 12 | 20 | | 2004 | 8 | 14 | 22 | | 2005 | 8 | 15 | 23 | | 2006 | 7 | 17 | 24 | | 2007 | 8 | 10 | 18 | | 2008 | 11 | 15 | 26 | | 2009 | 9 | 27 | 36 | | 2010 | 8 | 8 | 16 | | 2011 | 7 | 14 | 21 | | 2012 | 5 | 18 | 23 | | 2013 | 3 | 8 | 11 | | 2014 | 2 | 18 | 20 | | 2015 | 6 | 13 | 19 | | 2016 | 1 | 11 | 12 | | 2017 | 2 | 11 | 13 | | 2018 | 0 | 14 | 14 | | 2019 | 3 | 12 | 15 | | 2020 | 2 | 9 | 11 | | 2021 | 4 | 7 | 11 | | 2022 | 2 | 11 | 13 | | 2023 | 3 | 12 | 15 | | 2024 | 3 | 6 | 9 | | 2025 | 4 | 4 | 8 | | 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.
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Sripada A, Varma R, Sirohi K, Sahu A, Verma M, Alam R. Sprouty2 modulates NF-?B signaling by sequestering the phosphatase PP2Ac in LPS-stimulated macrophages. J Immunol. 2026 Mar 17; 215(3).
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Zalucha EM, Hutch CR, Bethea M, Cook TM, Unadkat A, Wells KL, Kim KS, Maerz B, Lehrke M, Singer K, Sandoval DA. The Role of Pancreatic Preproglucagon in Regulating Local Inflammation in Mice. Cells. 2026 Mar 06; 15(5).
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Joyce LR, Akbari MS, Nguyen DT, Spencer BL, Rahkola J, McIver KS, Horswill AR, Doran KS, Keogh RA. Global genome analysis identifies glycolipids and lipoteichoic acid alanylation as contributors to group B streptococcal diabetic wound infection. Cell Rep. 2025 Nov 25; 44(11):116510.
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Sayegh R, Ledvina HE, Whiteley AT. Curli-independent defense against Bdellovibrio bacteriovorus in E. coli. Microbiol Spectr. 2025 Nov 04; 13(11):e0034225.
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Virk R, Behee M, Al-Shaer A, Wagner M, Armstrong M, Reisdorph N, Bathon B, Beatty N, Davis T, Yaeger MJ, Gray RS, Bridges MD, Gowdy KM, Shaikh SR. Genetic deletion of Alx/Fpr2 differentially regulates pulmonary inflammation in the absence and presence of acute lung injury. Immunohorizons. 2025 Sep 17; 9(10).
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Poczobutt JM, Egersdorf N, Hiltabidle MS, Nishino K, Justice MJ, Rivera T, Dubois B, Borowiec A, Mousavi-Aghdas SA, Kopf K, Gally F, Matsuda J, Berdyshev EV, Petrache I. Short-Term Acid Sphingomyelinase Deficiency Exerts Proinflammatory and Antiapoptotic Effects during LPS-induced Lung Injury in Mice. Am J Respir Cell Mol Biol. 2025 Aug; 73(2):275-287.
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McElwee ER, Hatchell D, Alshareef M, Mallah K, Hall H, Robinson H, Eskandari R, Chang E, Sullivan S, Tomlinson S. Complement Modulation Mitigates Inflammation-Mediated Preterm Birth and Fetal Neural Inflammation. Cells. 2025 Jul 08; 14(14).
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Useinovic N, Newson A, Near M, Maksimovic S, Volvovitz B, Quillinan N, Jevtovic-Todorovic V. Anesthesia-induced developmental neurotoxicity in the setting of systemic inflammation: the role of microglia. Exp Biol Med (Maywood). 2025; 250:10549.
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Kroon S, Malcic D, Weidert L, Bircher L, Boldt L, Christen P, Kiefer P, Sintsova A, Nguyen BD, Barthel M, Steiger Y, Clerc M, Herzog MK, Chen C, Gül E, Guery B, Slack E, Sunagawa S, Vorholt JA, Maier L, Lacroix C, Hausmann A, Hardt WD. Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition. Nat Commun. 2025 Mar 20; 16(1):2760.
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Calhoun KM, Armantrout E, Poch K, Caceres S, Lovell VK, Jones M, Malcolm KC, Vestal B, Wheeler E, Rysavy N, Manzer J, Aboellail I, Chatterjee D, Nick JA. Prospective Analysis of urINe LAM to Eliminate NTM Sputum Screening (PAINLESS) study: Rationale and trial design for testing urine lipoarabinomannan as a marker of NTM lung infection in cystic fibrosis. PLoS One. 2025; 20(3):e0309191.
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