 Lipopolysaccharides
"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
| Descriptor ID |
D008070
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| MeSH Number(s) |
D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".
Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".
This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 2 | 3 | 5 | | 1996 | 6 | 10 | 16 | | 1997 | 4 | 8 | 12 | | 1998 | 4 | 9 | 13 | | 1999 | 4 | 10 | 14 | | 2000 | 4 | 12 | 16 | | 2001 | 11 | 17 | 28 | | 2002 | 13 | 22 | 35 | | 2003 | 8 | 12 | 20 | | 2004 | 8 | 14 | 22 | | 2005 | 8 | 15 | 23 | | 2006 | 7 | 16 | 23 | | 2007 | 9 | 11 | 20 | | 2008 | 10 | 15 | 25 | | 2009 | 9 | 25 | 34 | | 2010 | 8 | 8 | 16 | | 2011 | 7 | 13 | 20 | | 2012 | 5 | 18 | 23 | | 2013 | 3 | 8 | 11 | | 2014 | 2 | 18 | 20 | | 2015 | 6 | 13 | 19 | | 2016 | 2 | 11 | 13 | | 2017 | 2 | 12 | 14 | | 2018 | 0 | 14 | 14 | | 2019 | 3 | 12 | 15 | | 2020 | 2 | 9 | 11 | | 2021 | 4 | 7 | 11 | | 2022 | 2 | 10 | 12 | | 2023 | 3 | 11 | 14 | | 2024 | 3 | 6 | 9 | | 2025 | 2 | 3 | 5 |
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Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.
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Virk R, Behee M, Al-Shaer A, Wagner M, Armstrong M, Reisdorph N, Bathon B, Beatty N, Davis T, Yaeger MJ, Gray RS, Bridges MD, Gowdy KM, Shaikh SR. Genetic deletion of Alx/Fpr2 differentially regulates pulmonary inflammation in the absence and presence of acute lung injury. Immunohorizons. 2025 Sep 17; 9(10).
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McElwee ER, Hatchell D, Alshareef M, Mallah K, Hall H, Robinson H, Eskandari R, Chang E, Sullivan S, Tomlinson S. Complement Modulation Mitigates Inflammation-Mediated Preterm Birth and Fetal Neural Inflammation. Cells. 2025 Jul 08; 14(14).
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Useinovic N, Newson A, Near M, Maksimovic S, Volvovitz B, Quillinan N, Jevtovic-Todorovic V. Anesthesia-induced developmental neurotoxicity in the setting of systemic inflammation: the role of microglia. Exp Biol Med (Maywood). 2025; 250:10549.
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Kroon S, Malcic D, Weidert L, Bircher L, Boldt L, Christen P, Kiefer P, Sintsova A, Nguyen BD, Barthel M, Steiger Y, Clerc M, Herzog MK, Chen C, Gül E, Guery B, Slack E, Sunagawa S, Vorholt JA, Maier L, Lacroix C, Hausmann A, Hardt WD. Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition. Nat Commun. 2025 Mar 20; 16(1):2760.
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Calhoun KM, Armantrout E, Poch K, Caceres S, Lovell VK, Jones M, Malcolm KC, Vestal B, Wheeler E, Rysavy N, Manzer J, Aboellail I, Chatterjee D, Nick JA. Prospective Analysis of urINe LAM to Eliminate NTM Sputum Screening (PAINLESS) study: Rationale and trial design for testing urine lipoarabinomannan as a marker of NTM lung infection in cystic fibrosis. PLoS One. 2025; 20(3):e0309191.
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King EM, Zhao Y, Moore CM, Steinhart B, Anderson KC, Vestal B, Moore PK, McManus SA, Evans CM, Mould KJ, Redente EF, McCubbrey AL, Janssen WJ. Gpnmb and Spp1 mark a conserved macrophage injury response masking fibrosis-specific programming in the lung. JCI Insight. 2024 Dec 20; 9(24).
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Wallbank A, Sosa A, Colson A, Farooqi H, Kaye E, Warner K, Albers DJ, Sottile PD, Smith BJ. Dynamic driving pressure predicts ventilator-induced lung injury in mice with and without endotoxin-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2025 Jan 01; 328(1):L159-L175.
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Valencia-Sanchez S, Davis M, Martensen J, Hoeffer C, Link C, Opp MR. Sleep-wake behavior and responses to sleep deprivation and immune challenge of protein kinase RNA-activated knockout mice. Brain Behav Immun. 2024 Oct; 121:74-86.
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Frank MG, Ball JB, Hopkins S, Kelley T, Kuzma AJ, Thompson RS, Fleshner M, Maier SF. SARS-CoV-2 S1 subunit produces a protracted priming of the neuroinflammatory, physiological, and behavioral responses to a remote immune challenge: A role for corticosteroids. Brain Behav Immun. 2024 Oct; 121:87-103.
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Jiang L, Lunding LP, Webber WS, Beckmann K, Azam T, Falkesgaard H?jen J, Amo-Aparicio J, Dinarello A, Nguyen TT, Pessara U, Parera D, Orlicky DJ, Fischer S, Wegmann M, Dinarello CA, Li S. An antibody to IL-1 receptor 7 protects mice from LPS-induced tissue and systemic inflammation. Front Immunol. 2024; 15:1427100.
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