 Viral Nonstructural Proteins
"Viral Nonstructural Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
| Descriptor ID |
D017361
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| MeSH Number(s) |
D12.776.964.900
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| Concept/Terms |
Viral Nonstructural Proteins- Viral Nonstructural Proteins
- Proteins, Viral Nonstructural
- NS Proteins, Viral
- Proteins, Viral NS
- Viral Nonstructural Protein
- Nonstructural Protein, Viral
- Protein, Viral Nonstructural
- Viral NS Proteins
- Nonstructural Proteins, Viral
- Viral Non-Structural Proteins
- Non-Structural Proteins, Viral
- Proteins, Viral Non-Structural
- Viral Non Structural Proteins
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Below are MeSH descriptors whose meaning is more general than "Viral Nonstructural Proteins".
Below are MeSH descriptors whose meaning is more specific than "Viral Nonstructural Proteins".
This graph shows the total number of publications written about "Viral Nonstructural Proteins" by people in this website by year, and whether "Viral Nonstructural Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 2 | 1 | 3 | | 2008 | 2 | 1 | 3 | | 2009 | 0 | 1 | 1 | | 2010 | 2 | 1 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 2 | 2 | 4 | | 2015 | 1 | 2 | 3 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 3 | 4 | | 2018 | 3 | 0 | 3 | | 2019 | 1 | 1 | 2 | | 2020 | 2 | 3 | 5 | | 2021 | 4 | 1 | 5 | | 2023 | 1 | 0 | 1 | | 2024 | 1 | 1 | 2 | | 2025 | 2 | 4 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Viral Nonstructural Proteins" by people in Profiles.
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Zhang Z, Uribe I, Davis KA, McPherson RL, Larson GP, Badiee M, Tran V, Ledwith MP, Feltman EM, Yú S, Caì Y, Chang CY, Yang X, Ma Z, Chang P, Kuhn JH, Leung AKL, Mehle A. Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection. Nat Commun. 2025 Dec 17; 16(1):11176.
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Sears JD, Popov KI, Sylvester PA, Dickmander R, Diaz J, Chang CK, Huff J, Sanders W, Saba NA, Sorensen M, Drobish AM, May NA, Namitz K, Fecko J, Yennawar NH, Morrison TE, Tropsha A, Heise MT, Moorman NJ. Novel computational pipeline to identify target sites for broad spectrum antiviral drugs. Antiviral Res. 2026 Jan; 245:106322.
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Han WM, Solomon SS, Smeaton L, Avihingsanon A, Wagner Cardoso S, Li J, Parvangada A, Sulkowski M, Naggie S, Martin R, Mo H, Maiorova E, Wyles D. Reinfection and Resistance Associated Substitutions Following a Minimal Monitoring Approach for Hepatitis C Virus Treatment in MINMON Trial. Clin Infect Dis. 2025 Jul 18; 80(6):1293-1301.
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Muthu Ramalingam B, Sears JD, Talbot KM, Su YN, Houliston S, Hossain MA, Davis-Gilbert ZW, Zhao C, Oh HJ, Brown PJ, Sanders MK, Moorman SR, Ojha D, Burdick JE, Law I, Morales NL, Martinez SA, Loppnau P, Garcia Perez J, Drobish AM, Morrison TE, Streblow ZJ, Streblow DN, Arrowsmith CH, Vargason A, Couñago RM, Halabelian L, Arnold JJ, Cameron CE, Moorman NJ, Heise MT, Willson TM. Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity. J Med Chem. 2025 Jul 24; 68(14):14514-14536.
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Mahajan S, Kumar R, Singh A, Dhaka P, Pareek A, Kumar P, Tomar S. Targeting the host protein G3BP1 for the discovery of novel antiviral inhibitors against Chikungunya virus. Virology. 2025 07; 608:110551.
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Yin P, Sobolik EB, May NA, Wang S, Fayed A, Vyshenska D, Drobish AM, Parks MG, Lello LS, Merits A, Morrison TE, Greninger AL, Kielian M. Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine. PLoS Pathog. 2025 Jan; 21(1):e1012859.
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Zhu J, Lai Y, Cheng M, Dash RC, Guo S, Guo J, Su Y, Wolek A, Issacs B, Liu Z, Li Q, Mishra N, Garmendia A, Hadden MK, Tian XC, He X, Tang Y. Discovery of small molecules against porcine reproductive and respiratory syndrome virus replication by targeting NendoU activity. J Virol. 2025 02 25; 99(2):e0203424.
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Hossain F, Ghosh P, Chowdhury FR, Basher A, Ahsan HMN, Khan AH, Shumu SJ, Jahan T, Roy CK, Arefin AKMN, Khanam F, Rahat MA, Chowdhury R, Uddin MR, Shomik MS, Maruf S, Rashid MU, Sagar SK, Mithila NT, Chowdhury MAA, Kamal M, Sharfaraz A, Ghosh D, Chowdhury A, Chowdhury AH, Hossain Z, Arefeen F, Islam MS, Rahman SMM, Al-Amin TM, Rashid A, Shukla KK, Roy S, Rana MS, Hossain MS, Siegel M, Wahed AAE, Mondal D. Evaluating a rapid molecular assay in a mobile laboratory for improved diagnosis of dengue in Bangladesh. Int J Infect Dis. 2025 Jan; 150:107299.
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Ware BC, Parks MG, da Silva MOL, Morrison TE. Chikungunya virus infection disrupts MHC-I antigen presentation via nonstructural protein 2. PLoS Pathog. 2024 Mar; 20(3):e1011794.
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Maurina SF, O'Sullivan JP, Sharma G, Pineda Rodriguez DC, MacFadden A, Cendali F, Henen MA, Vögeli B, Kieft JS, Glasgow A, Steckelberg AL. An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by ß-coronavirus Non-structural Protein 1. J Mol Biol. 2023 10 15; 435(20):168259.
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