 Viral Nonstructural Proteins
"Viral Nonstructural Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
| Descriptor ID |
D017361
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| MeSH Number(s) |
D12.776.964.900
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| Concept/Terms |
Viral Nonstructural Proteins- Viral Nonstructural Proteins
- Proteins, Viral Nonstructural
- NS Proteins, Viral
- Proteins, Viral NS
- Viral Nonstructural Protein
- Nonstructural Protein, Viral
- Protein, Viral Nonstructural
- Viral NS Proteins
- Nonstructural Proteins, Viral
- Viral Non-Structural Proteins
- Non-Structural Proteins, Viral
- Proteins, Viral Non-Structural
- Viral Non Structural Proteins
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Below are MeSH descriptors whose meaning is more general than "Viral Nonstructural Proteins".
Below are MeSH descriptors whose meaning is more specific than "Viral Nonstructural Proteins".
This graph shows the total number of publications written about "Viral Nonstructural Proteins" by people in this website by year, and whether "Viral Nonstructural Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 2 | 1 | 3 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 1 | 2 | | 2010 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 3 | 4 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 3 | 4 | | 2018 | 3 | 0 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 3 | 4 | | 2021 | 4 | 1 | 5 | | 2023 | 1 | 0 | 1 | | 2024 | 0 | 1 | 1 | | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Viral Nonstructural Proteins" by people in Profiles.
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Mahajan S, Kumar R, Singh A, Dhaka P, Pareek A, Kumar P, Tomar S. Targeting the host protein G3BP1 for the discovery of novel antiviral inhibitors against Chikungunya virus. Virology. 2025 Jul; 608:110551.
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Yin P, Sobolik EB, May NA, Wang S, Fayed A, Vyshenska D, Drobish AM, Parks MG, Lello LS, Merits A, Morrison TE, Greninger AL, Kielian M. Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine. PLoS Pathog. 2025 Jan; 21(1):e1012859.
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Ware BC, Parks MG, da Silva MOL, Morrison TE. Chikungunya virus infection disrupts MHC-I antigen presentation via nonstructural protein 2. PLoS Pathog. 2024 Mar; 20(3):e1011794.
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Maurina SF, O'Sullivan JP, Sharma G, Pineda Rodriguez DC, MacFadden A, Cendali F, Henen MA, V?geli B, Kieft JS, Glasgow A, Steckelberg AL. An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by ?-coronavirus Non-structural Protein 1. J Mol Biol. 2023 10 15; 435(20):168259.
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Showers WM, Leach SM, Kechris K, Strong M. Longitudinal analysis of SARS-CoV-2 spike and RNA-dependent RNA polymerase protein sequences reveals the emergence and geographic distribution of diverse mutations. Infect Genet Evol. 2022 01; 97:105153.
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Burke JM, St Clair LA, Perera R, Parker R. SARS-CoV-2 infection triggers widespread host mRNA decay leading to an mRNA export block. RNA. 2021 11; 27(11):1318-1329.
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Canal B, Fujisawa R, McClure AW, Deegan TD, Wu M, Ulferts R, Weissmann F, Drury LS, Bertolin AP, Zeng J, Beale R, Howell M, Labib K, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease. Biochem J. 2021 07 16; 478(13):2465-2479.
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Canal B, McClure AW, Curran JF, Wu M, Ulferts R, Weissmann F, Zeng J, Bertolin AP, Milligan JC, Basu S, Drury LS, Deegan TD, Fujisawa R, Roberts EL, Basier C, Labib K, Beale R, Howell M, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease. Biochem J. 2021 07 16; 478(13):2445-2464.
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Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, Tan KW, Lim CT, Basier C, Canal B, Curran JF, Drury LS, McClure AW, Roberts EL, Weissmann F, Zeisner TU, Beale R, Cowling VH, Howell M, Labib K, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase. Biochem J. 2021 07 16; 478(13):2481-2497.
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Haist KC, Carpentier KS, Davenport BJ, Morrison TE. Plasmacytoid Dendritic Cells Mediate Control of Ross River Virus Infection via a Type I Interferon-Dependent, MAVS-Independent Mechanism. J Virol. 2021 02 24; 95(6).
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