 High-Throughput Nucleotide Sequencing
"High-Throughput Nucleotide Sequencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.
| Descriptor ID |
D059014
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| MeSH Number(s) |
E05.393.760.319
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| Concept/Terms |
High-Throughput Nucleotide Sequencing- High-Throughput Nucleotide Sequencing
- High Throughput Nucleotide Sequencing
- Nucleotide Sequencing, High-Throughput
- Sequencing, High-Throughput Nucleotide
Massively-Parallel Sequencing- Massively-Parallel Sequencing
- Massively Parallel Sequencing
- Sequencing, Massively-Parallel
- Sequencings, Massively-Parallel
High-Throughput RNA Sequencing- High-Throughput RNA Sequencing
- High Throughput RNA Sequencing
- RNA Sequencing, High-Throughput
- Sequencing, High-Throughput RNA
Deep Sequencing- Deep Sequencing
- Deep Sequencings
- Sequencing, Deep
- Sequencings, Deep
High-Throughput DNA Sequencing- High-Throughput DNA Sequencing
- DNA Sequencing, High-Throughput
- High Throughput DNA Sequencing
- High-Throughput DNA Sequencings
- Sequencing, High-Throughput DNA
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Below are MeSH descriptors whose meaning is more general than "High-Throughput Nucleotide Sequencing".
Below are MeSH descriptors whose meaning is more specific than "High-Throughput Nucleotide Sequencing".
This graph shows the total number of publications written about "High-Throughput Nucleotide Sequencing" by people in this website by year, and whether "High-Throughput Nucleotide Sequencing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2008 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 3 | 4 | 7 | | 2012 | 5 | 6 | 11 | | 2013 | 10 | 17 | 27 | | 2014 | 8 | 16 | 24 | | 2015 | 7 | 32 | 39 | | 2016 | 7 | 31 | 38 | | 2017 | 8 | 21 | 29 | | 2018 | 20 | 24 | 44 | | 2019 | 10 | 18 | 28 | | 2020 | 2 | 18 | 20 | | 2021 | 5 | 21 | 26 | | 2022 | 5 | 13 | 18 | | 2023 | 1 | 15 | 16 | | 2024 | 6 | 8 | 14 | | 2025 | 4 | 18 | 22 | | 2026 | 6 | 8 | 14 |
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Below are the most recent publications written about "High-Throughput Nucleotide Sequencing" by people in Profiles.
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Han WM, Solomon S, Wagner-Cardoso S, Li J, Parvangada A, Sulkowski M, Naggie S, Martin R, Mo H, Maiorova E, Wyles D. Rare and Novel Hepatitis C Virus Genotype Subtypes and Response to Sofosbuvir/Velpatasvir in A5360 (MINMON) Clinical Trial. J Viral Hepat. 2026 Nov; 33(11).
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Halper-Stromberg E, Narayan S, Laufer V, Limson M, Busse T, Segal JP, Aisner DL, Morrissette JJD, Thorvaldsdottir H, Robinson JT, Roy S, Tjota MY. Clinical Variant Interpretation with the Integrative Genomics Viewer (IGV) for Molecular Pathologists. J Vis Exp. 2026 08 14; (234).
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Eno CC, Sompallae R, Jones D, Aisner DL, Senaratne TN. Next-Generation Sequencing Reporting Practices among the Genomics Organization for Academic Laboratories Institutions: Current State and Opportunities for Harmonization. J Mol Diagn. 2026 Oct; 28(10):748-758.
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Lee YH, Rinn JL, Hwang T. Protocol for massively parallel RNA assay combined with immunoprecipitation for high-throughput analysis of RNA-protein interactions in cells. STAR Protoc. 2026 Jun 19; 7(2):104624.
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Concepcion BP, Bestard O, Samaniego-Picota M, Prashar R, Ansari MJ, Comai G, Gessaroli E, Rostaing L, Alberici F, Mannon RB, Augustine J, Wee A, Poggio E, DiCocco P, Leca N, Shawar S, Bhati C, Maluf D, Rothstein DM, Cherukuri A, Chang A, Salem F, Kattan MW, Schold JD, Connolly P, Rose A, Doshi N, Gallon L, Donovan MJ. A Pre-Kidney Transplant Blood-Based Next-Generation Sequencing Assay to Predict Early Acute Rejection. Kidney360. 2026 Aug 01; 7(8):1792-1806.
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Yu J, Ahmann LS, Yao YY, Toland A, Snowden A, Ho C, Loyfer N, Kaplan T, Vogel H, Wang L, Howitt BE, Holmes B, Lowe AC, Gu W. Enriched methylomes of low-input and fragmented DNA using fragment ligation EXclusive methylation sequencing. Nucleic Acids Res. 2026 May 05; 54(9).
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Rabban JT, Wolsky RJ, Kayraklioglu N, Davies KD, Aisner DL, Devine WP. Copy Number-low/TP53-mutated Endometrial Cancer With Wild-type p53 Immunoexpression: Implications for Risk Stratification and Management When Using Next-generation Sequencing for Molecular Classification. Mod Pathol. 2026 06; 39(6):101005.
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Fought MK, Hong G, Quinn AC, Wagner BD, Robertson CE, Harris JK, Laguna TA. Molecular Methods to Detect and Quantify Fungal Communities in Cystic Fibrosis Airway Specimens. Pediatr Pulmonol. 2026 Apr; 61(4):e71598.
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Ortendahl JD, Carter GC, Zantema EM, Hoag JR, Starodynov A, White KL, Basu GD, Tharayanil A, De La O JP, Hall DW, Baehner FL. Costs and benefits of whole-exome, whole-transcriptome sequencing versus 50-gene panels for genomic profiling in solid tumors. J Med Econ. 2026 Dec; 29(1):1046-1058.
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Das R, Kleinberger J, Sawas T, Wald AI, Bubar R, Singh H, Chennat J, Khalid A, Romutis SL, Rabinovitz M, Tavakkoli A, Fairley KJ, Boone BA, Sarkaria S, Nasr J, Thiruvengadam NR, Gabbert C, Mahmood S, Messallam AA, Gjeorgjievski M, Goldschmiedt M, Thakkar S, Tielleman T, Dugum M, Reich J, Singh S, Brand RE, McGrath K, Fasanella K, Lennon AM, Reddy R, Shrestha R, Ellis DJ, Singhi SA, Lee T, Kay PS, Lee RD, Chua TY, Nassour I, Buxbaum JL, Law JK, Bhat Y, Jamidar PA, Jonica ER, Easler JJ, Skef W, Vanderveldt HD, Dasyam AK, Geller DA, Zureikat AH, Zeh HJ, Polanco PM, Marsh JW, Hogg M, Lee KK, Pingpank JF, Choudry MHA, Humar A, Schmidt C, Mansour J, Nunns G, Ongchin M, Paniccia A, Lajara S, Monaco SE, Ohori NP, Pantanowitz L, Mitchell JM, Smith K, Shaker N, Singhi AH, Hsu D, Saeed A, Sahin IH, Zhang J, Gorantla V, Rhee J, Nikiforova MN, Kubiliun N, Slivka A, Singhi AD. DNA/RNA-Based Next-Generation Sequencing Improves the Early Diagnosis and Management of Neoplastic Bile Duct Strictures: A 6-Year, Prospective, Multi-Institutional, Real-Time Study. Gastroenterology. 2026 Aug; 171(2):325-341.
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