 Tunicamycin
"Tunicamycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.
| Descriptor ID |
D014415
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| MeSH Number(s) |
D03.383.742.680.725 D13.570.685.725
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tunicamycin".
Below are MeSH descriptors whose meaning is more specific than "Tunicamycin".
This graph shows the total number of publications written about "Tunicamycin" by people in this website by year, and whether "Tunicamycin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tunicamycin" by people in Profiles.
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Pires Da Silva J, Monceaux K, Guilbert A, Gressette M, Piquereau J, Novotova M, Ventura-Clapier R, Garnier A, Lemaire C. SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy. Cells. 2020 02 12; 9(2).
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Prola A, Nichtova Z, Pires Da Silva J, Piquereau J, Monceaux K, Guilbert A, Gressette M, Ventura-Clapier R, Garnier A, Zahradnik I, Novotova M, Lemaire C. Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes. Cardiovasc Res. 2019 02 01; 115(2):328-342.
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Cherry PD, White LK, York K, Hesselberth JR. Genetic bypass of essential RNA repair enzymes in budding yeast. RNA. 2018 03; 24(3):313-323.
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Chen MZ, Moily NS, Bridgford JL, Wood RJ, Radwan M, Smith TA, Song Z, Tang BZ, Tilley L, Xu X, Reid GE, Pouladi MA, Hong Y, Hatters DM. A thiol probe for measuring unfolded protein load and proteostasis in cells. Nat Commun. 2017 09 07; 8(1):474.
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Prola A, Pires Da Silva J, Guilbert A, Lecru L, Piquereau J, Ribeiro M, Mateo P, Gressette M, Fortin D, Boursier C, Gallerne C, Caillard A, Samuel JL, Fran?ois H, Sinclair DA, Eid P, Ventura-Clapier R, Garnier A, Lemaire C. SIRT1 protects the heart from ER stress-induced cell death through eIF2a deacetylation. Cell Death Differ. 2017 02; 24(2):343-356.
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Inge LJ, Friel JM, Richer AL, Fowler AJ, Whitsett T, Smith MA, Tran NL, Bremner RM. LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress. Cancer Lett. 2014 Oct 01; 352(2):187-95.
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Maclean KN, Greiner LS, Evans JR, Sood SK, Lhotak S, Markham NE, Stabler SP, Allen RH, Austin RC, Balasubramaniam V, Jiang H. Cystathionine protects against endoplasmic reticulum stress-induced lipid accumulation, tissue injury, and apoptotic cell death. J Biol Chem. 2012 Sep 14; 287(38):31994-2005.
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Rahman SM, Qadri I, Janssen RC, Friedman JE. Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis. J Lipid Res. 2009 Nov; 50(11):2193-202.
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Narasimhan J, Joyce BR, Naguleswaran A, Smith AT, Livingston MR, Dixon SE, Coppens I, Wek RC, Sullivan WJ. Translation regulation by eukaryotic initiation factor-2 kinases in the development of latent cysts in Toxoplasma gondii. J Biol Chem. 2008 Jun 13; 283(24):16591-601.
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Vij N, Zeitlin PL. Regulation of the ClC-2 lung epithelial chloride channel by glycosylation of SP1. Am J Respir Cell Mol Biol. 2006 Jun; 34(6):754-9.
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