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Michael Andres McMurray

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Cell and Devopmental Bio
Phone303/724-6569

    Collapse Research 
    Collapse research activities and funding
    R35GM148198     (MCMURRAY, MICHAEL A)Jan 1, 2023 - Dec 31, 2027
    NIH
    Mechanisms of septin assembly that shape cellular function
    Role: Principal Investigator
    R01GM124024     (MCMURRAY, MICHAEL A)Sep 30, 2017 - Jun 30, 2022
    NIH
    Requirements for cytosolic chaperones in the de novo folding of septin proteins
    Role: Principal Investigator
    R00GM086603     (MCMURRAY, MICHAEL A)Dec 1, 2008 - Aug 31, 2014
    NIH
    Mechanisms of assembly and inheritance of yeast septin-containing structures
    Role: Principal Investigator
    K99GM086603     (MCMURRAY, MICHAEL A)Dec 1, 2008 - Aug 31, 2011
    NIH
    Mechanisms of assembly and inheritance of yeast septin-containing structures
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hussain A, Nguyen VT, Reigan P, McMurray M. Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface. Front Cell Dev Biol. 2023; 11:1296657. PMID: 38125875.
      View in: PubMed
    2. Benson A, McMurray M. Simultaneous co-overexpression of Saccharomyces cerevisiae septins Cdc3 and Cdc10 drives pervasive, phospholipid-, and tag-dependent plasma membrane localization. Cytoskeleton (Hoboken). 2023 Jul-Aug; 80(7-8):199-214. PMID: 37098755.
      View in: PubMed
    3. Hassell D, Denney A, Singer E, Benson A, Roth A, Ceglowski J, Steingesser M, McMurray M. Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins. Mol Biol Cell. 2022 10 01; 33(12):ar111. PMID: 35947497.
      View in: PubMed
    4. Galvin J, Curran E, Arteaga F, Goossens A, Aubuchon-Endsley N, McMurray MA, Moore J, Hansen KC, Chial HJ, Potter H, Brodsky JL, Coughlan CM. Proteasome activity modulates amyloid toxicity. FEMS Yeast Res. 2022 03 09; 22(1). PMID: 35150241.
      View in: PubMed
    5. Baillet A, McMurray MA, Oakes PW. Meeting report - the ever-fascinating world of septins. J Cell Sci. 2021 12 15; 134(24). PMID: 34910818.
      View in: PubMed
    6. Hassell DS, Steingesser MG, Denney AS, Johnson CR, McMurray MA. Chemical rescue of mutant proteins in living Saccharomyces cerevisiae cells by naturally occurring small molecules. G3 (Bethesda). 2021 09 06; 11(9). PMID: 34544143.
      View in: PubMed
    7. Denney AS, Weems AD, McMurray MA. Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast. G3 (Bethesda). 2021 09 06; 11(9). PMID: 34544131.
      View in: PubMed
    8. Yeager R, Bushkin GG, Singer E, Fu R, Cooperman B, McMurray M. Post-Transcriptional Control of Mating-Type Gene Expression during Gametogenesis in Saccharomyces cerevisiae. Biomolecules. 2021 08 17; 11(8). PMID: 34439889.
      View in: PubMed
    9. Heasley LR, Singer E, Cooperman BJ, McMurray MA. Saccharomyces spores are born prepolarized to outgrow away from spore-spore connections and penetrate the ascus wall. Yeast. 2021 01; 38(1):90-101. PMID: 33238051.
      View in: PubMed
    10. Spiliotis ET, McMurray MA. Masters of asymmetry - lessons and perspectives from 50 years of septins. Mol Biol Cell. 2020 10 01; 31(21):2289-2297. PMID: 32991244.
      View in: PubMed
    11. Johnson CR, Steingesser MG, Weems AD, Khan A, Gladfelter A, Bertin A, McMurray MA. Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast. Elife. 2020 01 28; 9. PMID: 31990274.
      View in: PubMed
    12. McMurray MA, Thorner J. Turning it inside out: The organization of human septin heterooligomers. Cytoskeleton (Hoboken). 2019 09; 76(9-10):449-456. PMID: 31614074.
      View in: PubMed
    13. McMurray MA. The long and short of membrane curvature sensing by septins. J Cell Biol. 2019 Apr 01; 218(4):1083-1085. PMID: 30890557.
      View in: PubMed
    14. Barve G, Sridhar S, Aher A, Sahani MH, Chinchwadkar S, Singh S, K N L, McMurray MA, Manjithaya R. Septins are involved at the early stages of macroautophagy in S. cerevisiae. J Cell Sci. 2018 02 22; 131(4). PMID: 29361537.
      View in: PubMed
    15. Weems A, McMurray M. The step-wise pathway of septin hetero-octamer assembly in budding yeast. Elife. 2017 05 25; 6. PMID: 28541184.
      View in: PubMed
    16. McMurray MA. Coupling de novo protein folding with subunit exchange into pre-formed oligomeric protein complexes: the 'heritable template' hypothesis. Biomol Concepts. 2016 Dec 01; 7(5-6):271-281. PMID: 27875316.
      View in: PubMed
    17. Schaefer RM, Heasley LR, Odde DJ, McMurray MA. Kinetic partitioning during de novo septin filament assembly creates a critical G1 "window of opportunity" for mutant septin function. Cell Cycle. 2016 Sep 16; 15(18):2441-53. PMID: 27398993.
      View in: PubMed
    18. McMurray MA. Assays for genetic dissection of septin filament assembly in yeast, from de novo folding through polymerization. Methods Cell Biol. 2016; 136:99-116. PMID: 27473905.
      View in: PubMed
    19. Heasley LR, McMurray MA. Small molecule perturbations of septins. Methods Cell Biol. 2016; 136:311-9. PMID: 27473917.
      View in: PubMed
    20. Garcia G, Finnigan GC, Heasley LR, Sterling SM, Aggarwal A, Pearson CG, Nogales E, McMurray MA, Thorner J. Assembly, molecular organization, and membrane-binding properties of development-specific septins. J Cell Biol. 2016 Feb 29; 212(5):515-29. PMID: 26929450.
      View in: PubMed
    21. Heasley LR, McMurray MA. Roles of septins in prospore membrane morphogenesis and spore wall assembly in Saccharomyces cerevisiae. Mol Biol Cell. 2016 Feb 01; 27(3):442-50. PMID: 26680739.
      View in: PubMed
    22. Johnson CR, Weems AD, Brewer JM, Thorner J, McMurray MA. Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast. Mol Biol Cell. 2015 Apr 01; 26(7):1323-44. PMID: 25673805.
      View in: PubMed
    23. Heasley LR, Garcia G, McMurray MA. Off-target effects of the septin drug forchlorfenuron on nonplant eukaryotes. Eukaryot Cell. 2014 Nov; 13(11):1411-20. PMID: 25217460.
      View in: PubMed
    24. McMurray M. Lean forward: Genetic analysis of temperature-sensitive mutants unfolds the secrets of oligomeric protein complex assembly. Bioessays. 2014 Sep; 36(9):836-46. PMID: 25048147.
      View in: PubMed
    25. Weems AD, Johnson CR, Argueso JL, McMurray MA. Higher-order septin assembly is driven by GTP-promoted conformational changes: evidence from unbiased mutational analysis in Saccharomyces cerevisiae. Genetics. 2014 Mar; 196(3):711-27. PMID: 24398420.
      View in: PubMed
    26. de Val N, McMurray MA, Lam LH, Hsiung CC, Bertin A, Nogales E, Thorner J. Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins. Proteins. 2013 Nov; 81(11):1964-79. PMID: 23775754.
      View in: PubMed
    27. Bertin A, McMurray MA, Pierson J, Thai L, McDonald KL, Zehr EA, Garc?a G, Peters P, Thorner J, Nogales E. Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae. Mol Biol Cell. 2012 Feb; 23(3):423-32. PMID: 22160597.
      View in: PubMed
    28. Garcia G, Bertin A, Li Z, Song Y, McMurray MA, Thorner J, Nogales E. Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation. J Cell Biol. 2011 Dec 12; 195(6):993-1004. PMID: 22144691.
      View in: PubMed
    29. McMurray MA, Stefan CJ, Wemmer M, Odorizzi G, Emr SD, Thorner J. Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis. Biol Chem. 2011 Aug; 392(8-9):699-712. PMID: 21824003.
      View in: PubMed
    30. McMurray MA, Bertin A, Garcia G, Lam L, Nogales E, Thorner J. Septin filament formation is essential in budding yeast. Dev Cell. 2011 Apr 19; 20(4):540-9. PMID: 21497764.
      View in: PubMed
    31. Bertin A, McMurray MA, Thai L, Garcia G, Votin V, Grob P, Allyn T, Thorner J, Nogales E. Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization. J Mol Biol. 2010 Dec 10; 404(4):711-31. PMID: 20951708.
      View in: PubMed
    32. Garrenton LS, Stefan CJ, McMurray MA, Emr SD, Thorner J. Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Proc Natl Acad Sci U S A. 2010 Jun 29; 107(26):11805-10. PMID: 20547860.
      View in: PubMed
    33. McMurray MA, Thorner J. Septins: molecular partitioning and the generation of cellular asymmetry. Cell Div. 2009 Aug 26; 4:18. PMID: 19709431.
      View in: PubMed
    34. Veatch JR, McMurray MA, Nelson ZW, Gottschling DE. Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell. 2009 Jun 26; 137(7):1247-58. PMID: 19563757.
      View in: PubMed
    35. McMurray MA, Thorner J. Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast. Cell Cycle. 2009 Jan 15; 8(2):195-203. PMID: 19164941.
      View in: PubMed
    36. McMurray MA, Thorner J. Septin stability and recycling during dynamic structural transitions in cell division and development. Curr Biol. 2008 Aug 26; 18(16):1203-8. PMID: 18701287.
      View in: PubMed
    37. Bertin A, McMurray MA, Grob P, Park SS, Garcia G, Patanwala I, Ng HL, Alber T, Thorner J, Nogales E. Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8274-9. PMID: 18550837.
      View in: PubMed
    38. McMurray MA, Gottschling DE. Aging and genetic instability in yeast. Curr Opin Microbiol. 2004 Dec; 7(6):673-9. PMID: 15556042.
      View in: PubMed
    39. McMurray MA, Gottschling DE. Genetic instability in aging yeast: a metastable hyperrecombinational state. Cold Spring Harb Symp Quant Biol. 2004; 69:339-47. PMID: 16117666.
      View in: PubMed
    40. McMurray MA, Gottschling DE. An age-induced switch to a hyper-recombinational state. Science. 2003 Sep 26; 301(5641):1908-11. PMID: 14512629.
      View in: PubMed
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