 Phosphorothioate Oligonucleotides
"Phosphorothioate Oligonucleotides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Modified oligonucleotides in which one of the oxygens of the phosphate group is replaced with a sulfur atom.
| Descriptor ID |
D054735
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| MeSH Number(s) |
D13.695.578.424.575
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphorothioate Oligonucleotides".
Below are MeSH descriptors whose meaning is more specific than "Phosphorothioate Oligonucleotides".
This graph shows the total number of publications written about "Phosphorothioate Oligonucleotides" by people in this website by year, and whether "Phosphorothioate Oligonucleotides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphorothioate Oligonucleotides" by people in Profiles.
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Walsh SM, Sheridan RM, Lucas ED, Doan TA, Ware BC, Schafer J, Fu R, Burchill MA, Hesselberth JR, Tamburini BAJ. Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node. Elife. 2021 04 12; 10.
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Kostov O, Liboska R, P?v O, Nov?k P, Rosenberg I. Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides. Molecules. 2019 May 15; 24(10).
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Maciaszek A, Jastrzebska K, Guga P. Homopurine RP-stereodefined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs. Org Biomol Chem. 2019 05 08; 17(18):4611-4620.
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Singh R. A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates. J Vis Exp. 2018 08 21; (138).
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Jastrzebska K, Maciaszek A, Dolot R, Bujacz G, Guga P. Thermal stability and conformation of antiparallel duplexes formed by P-stereodefined phosphorothioate DNA/LNA chimeric oligomers with DNA and RNA matrices. Org Biomol Chem. 2015 Oct 21; 13(39):10032-40.
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Velu CS, Chaubey A, Phelan JD, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcucci G, Bhat B, Gebelein B, Grimes HL. Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. J Clin Invest. 2014 Jan; 124(1):222-36.
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Dalby AB, Goodrich KJ, Pfingsten JS, Cech TR. RNA recognition by the DNA end-binding Ku heterodimer. RNA. 2013 Jun; 19(6):841-51.
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