 Virulence Factors
"Virulence Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
| Descriptor ID |
D037521
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| MeSH Number(s) |
D23.946.896
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| Concept/Terms |
Virulence Factors- Virulence Factors
- Factors, Virulence
- Pathogenicity Factors
- Factors, Pathogenicity
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Below are MeSH descriptors whose meaning is more general than "Virulence Factors".
Below are MeSH descriptors whose meaning is more specific than "Virulence Factors".
This graph shows the total number of publications written about "Virulence Factors" by people in this website by year, and whether "Virulence Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 1 | 2 | 3 | | 2006 | 1 | 2 | 3 | | 2007 | 2 | 0 | 2 | | 2008 | 6 | 1 | 7 | | 2009 | 1 | 1 | 2 | | 2010 | 5 | 6 | 11 | | 2011 | 5 | 3 | 8 | | 2012 | 2 | 2 | 4 | | 2013 | 6 | 6 | 12 | | 2014 | 10 | 1 | 11 | | 2015 | 4 | 3 | 7 | | 2016 | 5 | 2 | 7 | | 2017 | 4 | 4 | 8 | | 2018 | 3 | 1 | 4 | | 2019 | 2 | 4 | 6 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 2 | 3 | | 2022 | 1 | 5 | 6 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 2 | 3 | | 2025 | 2 | 3 | 5 | | 2026 | 1 | 4 | 5 |
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Below are the most recent publications written about "Virulence Factors" by people in Profiles.
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Stark DS, King M, Ibler AEM, Srour S, Brown F, Sheffield J, Baseer N, Vernon EG, Zhang Y, Staples C, Radoshevich L, Humphreys D. Typhoid Toxin of Salmonella enterica Induces ISG15 Responses Mediating Host Cell Survival and Counteracting Intracellular Infection. Mol Microbiol. 2026 Jun; 125(6):475-492.
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John MS, Chinnappan M, Sturges CI, Artami M, Bhattacharya M, Keogh RA, Kavanaugh JS, Jain S, Gedamu H, Komarovsky J, Velasquez M, Sharma T, McDonald JG, Horswill AR, Harris-Tryon TA. Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing. Nat Microbiol. 2026 Mar; 11(3):704-717.
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Penaranda C, Brenner EP, Clatworthy AE, Cosimi LA, Ravi J, Hung DT. Genomic comparison and phenotypic characterization of Pseudomonas aeruginosa isolates across environmental and diverse clinical isolation sites. mSystems. 2026 Mar 24; 11(3):e0136225.
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Zaidi S, Srivastava N, Ghosh M, Jain D, Prasad PN, Sood S, Khare SK. Anti-biofilm and anti-virulence activity of a rare actinobacteria Nocardia sp. EMB45 against Pseudomonas aeruginosa. Arch Microbiol. 2026 Jan 21; 208(3):145.
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Lee E, Redzic JS, Gordon B, Saviola AJ, Tran N, Maroney SP, Ashby NL, Shaw S, Fulte S, McCarty A, Holyoak T, Meyer N, Hansen KC, Clark SE, Eisenmesser E. Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes. Protein Sci. 2026 Jan; 35(1):e70411.
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Detweiler CS, Alav I. Beyond antibiotic resistance: evidence for resistance-nodulation-division (RND) efflux pumps as virulence determinants. Microbiol Mol Biol Rev. 2025 Dec 18; 89(4):e0027824.
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Lurie-Weinberger MN, Cohen A, Kon H, Kastel O, Keren-Paz A, Schwartz D, Lellouche J, Nutman A, Frenk S, Schechner V, Temkin E, Friberg LE, Daikos GL, Skiada A, Durante-Mangoni E, Yahav D, Leibovici L, Dickstein Y, Dishon Benattar Y, Paul M, Carmeli Y. Virulence factors are preserved within carbapenem-resistant Acinetobacter baumannii clades. Virulence. 2025 Dec; 16(1):2542489.
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Raab JE, Harju TB, Toperzer JD, Duncan-Lowey JK, Thomas CI, Darehshouri A, Goldberg MB, Russo BC. A translocation-competent pore is required for Shigella flexneri to escape from the double membrane vacuole during intercellular spread. mBio. 2025 Sep 10; 16(9):e0167425.
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Enroth TJ, Severn MM, Costa FG, Bovee AR, Wilkening RV, Nguyen DT, Langouët-Astrié C, Horswill AR. Global changes in Staphylococcus aureus virulence and metabolism during colonization of healthy skin. Infect Immun. 2025 04 08; 93(4):e0002825.
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Akbari MS, Joyce LR, Spencer BL, Brady A, McIver KS, Doran KS. Identification of glyoxalase A in group B Streptococcus and its contribution to methylglyoxal tolerance and virulence. Infect Immun. 2025 04 08; 93(4):e0054024.
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