Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Joaquin Espinosa

Concepts (328)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Down Syndrome
25
2025
477
7.130
Why?
Tumor Suppressor Protein p53
16
2025
509
4.250
Why?
Transcription, Genetic
12
2021
1416
2.150
Why?
Cyclin-Dependent Kinases
7
2022
129
1.980
Why?
Neoplasms
10
2025
2449
1.790
Why?
Transcriptional Activation
6
2023
367
1.630
Why?
Janus Kinase Inhibitors
2
2024
25
1.630
Why?
Chromosomes, Human, Pair 21
2
2024
43
1.530
Why?
Piperidines
2
2024
198
1.460
Why?
Pyrimidines
3
2024
459
1.370
Why?
Proteome
4
2024
438
1.370
Why?
Transcriptome
4
2024
874
1.270
Why?
Interferons
4
2023
193
1.220
Why?
Hypoxia
2
2024
1084
0.980
Why?
Antineoplastic Agents
5
2025
2054
0.960
Why?
Gene Regulatory Networks
2
2021
280
0.950
Why?
Immunoglobulins
1
2025
160
0.900
Why?
Erythropoiesis
1
2024
51
0.900
Why?
Heme
1
2024
77
0.870
Why?
Blood-Brain Barrier
1
2025
131
0.870
Why?
Receptors, Interferon
2
2023
50
0.850
Why?
Gene Expression Regulation, Neoplastic
8
2021
1344
0.820
Why?
Protein Phosphatase 2C
1
2022
15
0.820
Why?
Transcription Factors
9
2023
1647
0.770
Why?
Molecular Targeted Therapy
1
2025
390
0.760
Why?
Blood
1
2022
105
0.740
Why?
Arthritis, Psoriatic
1
2021
20
0.740
Why?
Cell Death
1
2022
354
0.720
Why?
Genes, Tumor Suppressor
1
2021
86
0.700
Why?
Oncogenes
1
2021
112
0.690
Why?
Proto-Oncogene Proteins c-mdm2
6
2025
64
0.680
Why?
Databases, Genetic
1
2021
230
0.670
Why?
Kynurenine
2
2023
114
0.660
Why?
Heart Defects, Congenital
2
2025
757
0.660
Why?
Trisomy
2
2019
77
0.650
Why?
Apoptosis
10
2023
2499
0.640
Why?
Interferon-alpha
2
2020
194
0.630
Why?
Signal Transduction
9
2024
4926
0.630
Why?
Humans
61
2025
129271
0.610
Why?
Tumor Suppressor Proteins
2
2018
314
0.610
Why?
Enhancer Elements, Genetic
1
2020
176
0.600
Why?
Cyclin-Dependent Kinase 8
6
2022
43
0.600
Why?
Metabolome
1
2021
338
0.580
Why?
Genomics
1
2021
717
0.500
Why?
Case-Control Studies
6
2025
3377
0.460
Why?
Cell Proliferation
6
2023
2375
0.460
Why?
Cell Line, Tumor
9
2023
3202
0.450
Why?
Animals
20
2025
35309
0.440
Why?
Proteomics
4
2025
1054
0.430
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
3
2024
274
0.430
Why?
Carcinoma, Squamous Cell
1
2018
625
0.420
Why?
Cyclins
3
2022
89
0.400
Why?
Mice
14
2024
16915
0.390
Why?
Datasets as Topic
2
2022
109
0.370
Why?
Cell Cycle Proteins
4
2023
584
0.350
Why?
RNA Polymerase II
4
2019
317
0.340
Why?
Triple Negative Breast Neoplasms
3
2019
197
0.340
Why?
Adult
9
2025
35497
0.320
Why?
Mediator Complex
3
2022
57
0.310
Why?
Female
19
2025
68556
0.290
Why?
Gene Expression Profiling
3
2024
1688
0.290
Why?
Biomarkers
4
2025
3968
0.290
Why?
Promoter Regions, Genetic
4
2013
1204
0.270
Why?
Proto-Oncogene Proteins
2
2023
635
0.270
Why?
Gene Expression Regulation
3
2012
2537
0.270
Why?
Adolescent
6
2025
20315
0.270
Why?
Cytokines
5
2024
2013
0.260
Why?
Cell Differentiation
2
2024
1887
0.250
Why?
Positive Transcriptional Elongation Factor B
1
2006
29
0.250
Why?
Cyclin-Dependent Kinase Inhibitor p21
4
2009
117
0.250
Why?
Cell Cycle
2
2008
589
0.250
Why?
Lung Neoplasms
1
2018
2342
0.250
Why?
Phosphorylation
4
2022
1710
0.240
Why?
Metabolomics
2
2021
652
0.240
Why?
Male
11
2025
63517
0.240
Why?
Protein Binding
5
2021
2120
0.230
Why?
Hemoglobin SC Disease
1
2023
13
0.220
Why?
Young Adult
4
2025
12392
0.220
Why?
Erythropoietin
1
2024
88
0.210
Why?
Homeodomain Proteins
2
2019
495
0.210
Why?
Oxidative Phosphorylation
1
2024
187
0.210
Why?
Liposarcoma
1
2023
27
0.210
Why?
Glutamine
1
2023
99
0.210
Why?
Cell Line
4
2019
2779
0.210
Why?
Alzheimer Disease
2
2020
514
0.210
Why?
Cyclin C
1
2022
2
0.210
Why?
Eukaryotic Initiation Factor-2
1
2022
26
0.200
Why?
Child, Preschool
4
2025
10459
0.200
Why?
Diabetic Neuropathies
1
2023
96
0.200
Why?
Growth Disorders
1
2022
80
0.200
Why?
Centrosome
2
2022
64
0.200
Why?
Gene Silencing
1
2023
190
0.190
Why?
Cerebellar Neoplasms
1
2023
151
0.190
Why?
DNA-Binding Proteins
3
2016
1446
0.190
Why?
Medulloblastoma
1
2023
192
0.180
Why?
Acetyltransferases
1
2001
21
0.180
Why?
Stress, Physiological
1
2024
414
0.180
Why?
Hematopoiesis
2
2021
183
0.180
Why?
Access to Information
1
2021
47
0.180
Why?
Doxorubicin
3
2007
328
0.180
Why?
Janus Kinase 1
1
2020
24
0.180
Why?
Cilia
2
2022
179
0.180
Why?
Janus Kinase 2
1
2020
32
0.180
Why?
Azetidines
1
2020
40
0.170
Why?
RNA, Messenger
3
2021
2703
0.170
Why?
Models, Biological
1
2008
1722
0.170
Why?
Up-Regulation
2
2021
839
0.170
Why?
Flow Cytometry
2
2019
1155
0.170
Why?
Insulin-Like Growth Factor I
1
2022
307
0.170
Why?
Data Mining
1
2021
109
0.170
Why?
MicroRNAs
2
2018
676
0.170
Why?
Nuclear Proteins
3
2023
659
0.170
Why?
Anemia, Sickle Cell
1
2023
252
0.170
Why?
Eosinophilic Esophagitis
1
2024
318
0.170
Why?
Quinolinic Acid
1
2019
8
0.170
Why?
Child
6
2025
20785
0.170
Why?
Connective Tissue Diseases
1
2020
82
0.160
Why?
Biosynthetic Pathways
1
2019
24
0.160
Why?
Heart Diseases
1
2023
350
0.160
Why?
Indoleamine-Pyrrole 2,3,-Dioxygenase
1
2019
55
0.160
Why?
Protein Domains
2
2017
253
0.160
Why?
Coinfection
1
2020
131
0.150
Why?
Middle Aged
5
2025
31091
0.150
Why?
Mice, Inbred C57BL
5
2020
5439
0.150
Why?
Genome, Human
1
2021
392
0.150
Why?
Calcinosis
1
2020
231
0.150
Why?
Nedd4 Ubiquitin Protein Ligases
1
2018
15
0.150
Why?
SOXB1 Transcription Factors
1
2019
57
0.150
Why?
Transforming Growth Factor beta2
1
2018
35
0.150
Why?
Forkhead Box Protein O3
1
2018
15
0.150
Why?
rhoA GTP-Binding Protein
1
2018
89
0.150
Why?
Epithelial Cells
1
2024
1063
0.150
Why?
Bacterial Infections
1
2020
235
0.150
Why?
TOR Serine-Threonine Kinases
1
2021
396
0.150
Why?
Stem Cell Niche
1
2018
53
0.140
Why?
Inflammation
2
2020
2737
0.140
Why?
Inpatients
1
2022
462
0.140
Why?
Receptor, Notch1
1
2018
61
0.140
Why?
Cell Survival
1
2021
1075
0.140
Why?
Hypersensitivity
1
2020
248
0.140
Why?
Autoimmunity
1
2023
862
0.140
Why?
Binding Sites
3
2014
1250
0.140
Why?
Apoptosis Regulatory Proteins
1
2018
182
0.140
Why?
Leukemia, Biphenotypic, Acute
1
2017
3
0.140
Why?
Hedgehog Proteins
1
2018
187
0.140
Why?
Sulfonamides
1
2020
495
0.130
Why?
Protein Kinase Inhibitors
2
2020
890
0.130
Why?
T-Lymphocytes
2
2022
1933
0.130
Why?
Histidine Kinase
1
2016
34
0.130
Why?
Osteosarcoma
1
2017
71
0.130
Why?
Antigens
1
2018
356
0.130
Why?
Exosomes
1
2017
96
0.130
Why?
Chromatin
4
2016
478
0.130
Why?
Proteolysis
1
2017
167
0.130
Why?
Neoplasm Recurrence, Local
2
2019
958
0.130
Why?
Interferon-gamma
1
2019
772
0.130
Why?
Adenosine Triphosphatases
1
2016
161
0.120
Why?
HCT116 Cells
3
2019
78
0.120
Why?
Colonic Neoplasms
1
2018
242
0.120
Why?
Ribosomal Proteins
1
2015
77
0.120
Why?
Autophagy
1
2018
266
0.120
Why?
Hematopoietic Stem Cells
1
2018
381
0.120
Why?
Disease Models, Animal
2
2023
4057
0.120
Why?
Nerve Tissue Proteins
1
2019
569
0.120
Why?
Phenotype
1
2023
3074
0.120
Why?
Bone Neoplasms
1
2017
231
0.120
Why?
Neoplastic Stem Cells
1
2019
379
0.110
Why?
Azepines
1
2015
88
0.110
Why?
Gene Expression
1
2019
1466
0.110
Why?
Repressor Proteins
1
2017
406
0.110
Why?
Fibroblasts
1
2019
948
0.110
Why?
Carrier Proteins
1
2018
742
0.110
Why?
Acetylation
2
2007
244
0.110
Why?
ets-Domain Protein Elk-1
1
2013
13
0.110
Why?
Mitogens
1
2013
59
0.110
Why?
Disease Progression
1
2021
2630
0.100
Why?
Down-Regulation
1
2015
636
0.100
Why?
Prospective Studies
1
2025
7123
0.100
Why?
Extracellular Signal-Regulated MAP Kinases
1
2013
169
0.100
Why?
Feedback, Physiological
1
2012
76
0.100
Why?
Tumor Cells, Cultured
3
2019
942
0.100
Why?
RNA Stability
1
2012
102
0.090
Why?
Hypertension, Pulmonary
1
2023
1894
0.090
Why?
Protein Structure, Tertiary
2
2006
841
0.090
Why?
Sirtuins
1
2010
39
0.080
Why?
HeLa Cells
3
2013
611
0.080
Why?
Histones
2
2007
588
0.080
Why?
Intracellular Signaling Peptides and Proteins
2
2023
442
0.080
Why?
S Phase
1
2009
75
0.080
Why?
Diabetes Mellitus, Type 2
1
2023
2439
0.080
Why?
Protamine Kinase
1
2008
8
0.080
Why?
Enzyme Activation
2
2008
812
0.080
Why?
Receptors, Thyroid Hormone
1
2008
21
0.080
Why?
Hydroxyurea
2
2023
34
0.070
Why?
RNA
1
2014
880
0.070
Why?
DNA Topoisomerases, Type II
1
2007
43
0.070
Why?
Multiprotein Complexes
1
2008
155
0.070
Why?
Genome-Wide Association Study
2
2025
1327
0.070
Why?
Formaldehyde
1
2007
60
0.070
Why?
Radiation, Ionizing
1
2007
76
0.070
Why?
Protein Kinases
1
2009
318
0.070
Why?
Glycolysis
2
2024
311
0.070
Why?
RNA Precursors
1
2007
147
0.070
Why?
Fluorouracil
1
2007
198
0.060
Why?
Transcription Factors, TFII
1
2006
40
0.060
Why?
High Mobility Group Proteins
1
2006
42
0.060
Why?
Kinetics
2
2007
1644
0.060
Why?
Transcriptional Elongation Factors
1
2006
36
0.060
Why?
Transcription Factor TFIIH
1
2006
39
0.060
Why?
Breast Neoplasms
1
2018
2140
0.060
Why?
Chromatin Immunoprecipitation
1
2006
132
0.060
Why?
Protein Transport
1
2007
428
0.060
Why?
Mice, Knockout
3
2019
2871
0.060
Why?
Serine
1
2006
138
0.060
Why?
Glucose
1
2010
1001
0.060
Why?
Protein Isoforms
1
2006
389
0.060
Why?
Xenograft Model Antitumor Assays
2
2019
812
0.060
Why?
Hemoglobin, Sickle
1
2023
18
0.050
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2006
947
0.050
Why?
Glutamates
1
2023
57
0.050
Why?
Intermediate Filaments
1
2023
27
0.050
Why?
Activating Transcription Factor 4
1
2023
20
0.050
Why?
Proteasome Inhibitors
1
2023
42
0.050
Why?
L-Selectin
1
2023
25
0.050
Why?
Proline
1
2023
76
0.050
Why?
Neurofilament Proteins
1
2023
43
0.050
Why?
Perforin
1
2023
19
0.050
Why?
Tyrosine
1
2023
223
0.050
Why?
Patient Acuity
1
2023
45
0.050
Why?
Proteasome Endopeptidase Complex
1
2023
148
0.050
Why?
Protein Tyrosine Phosphatases
1
2023
169
0.050
Why?
Esophagus
1
2024
248
0.050
Why?
Bile Acids and Salts
1
2023
195
0.050
Why?
Hemolysis
1
2023
199
0.050
Why?
Centrioles
1
2022
41
0.050
Why?
DNA Footprinting
1
2001
33
0.050
Why?
Cytoskeletal Proteins
1
2022
146
0.050
Why?
Neuroimaging
1
2024
278
0.050
Why?
p300-CBP Transcription Factors
1
2001
20
0.050
Why?
Immunoblotting
1
2001
305
0.040
Why?
Clonal Evolution
1
2021
39
0.040
Why?
Histone Acetyltransferases
1
2001
61
0.040
Why?
Germ-Line Mutation
1
2020
140
0.040
Why?
Cells, Cultured
2
2018
4077
0.040
Why?
Heterozygote
1
2020
272
0.040
Why?
Toll-Like Receptors
1
2020
179
0.040
Why?
Interferon Type I
1
2020
139
0.040
Why?
Genetic Testing
1
2022
428
0.040
Why?
Vesiculovirus
1
2019
16
0.040
Why?
Microtubules
1
2022
263
0.040
Why?
Purines
1
2020
172
0.040
Why?
Antigens, Neoplasm
1
2022
308
0.040
Why?
Immunotherapy
1
2024
592
0.040
Why?
Drosophila melanogaster
1
2001
210
0.040
Why?
Immunotherapy, Adoptive
1
2022
295
0.040
Why?
Heart
1
2023
637
0.040
Why?
STAT1 Transcription Factor
1
2019
70
0.040
Why?
Risk Factors
2
2025
9746
0.040
Why?
Nanog Homeobox Protein
1
2019
13
0.040
Why?
DNA
1
2006
1396
0.040
Why?
Myelopoiesis
1
2018
7
0.040
Why?
Lymphopoiesis
1
2018
25
0.040
Why?
Recombinant Fusion Proteins
1
2001
648
0.040
Why?
Mice, 129 Strain
1
2018
87
0.040
Why?
Mice, SCID
1
2019
350
0.040
Why?
MCF-7 Cells
1
2018
116
0.040
Why?
Receptors, Growth Factor
1
2017
55
0.040
Why?
Amyloid beta-Peptides
1
2020
211
0.040
Why?
Polymorphism, Single Nucleotide
1
2025
2063
0.040
Why?
Pyrazoles
1
2020
404
0.030
Why?
Ubiquitin-Conjugating Enzymes
1
2017
13
0.030
Why?
Mice, Inbred NOD
1
2019
588
0.030
Why?
Interleukin-1 Receptor-Associated Kinases
1
2017
27
0.030
Why?
CD8-Positive T-Lymphocytes
1
2023
857
0.030
Why?
Genetic Predisposition to Disease
1
2025
2276
0.030
Why?
CD4-Positive T-Lymphocytes
1
2023
1056
0.030
Why?
Neoplasm Metastasis
1
2019
610
0.030
Why?
Host-Pathogen Interactions
1
2019
351
0.030
Why?
Mitosis
1
2017
180
0.030
Why?
Myeloid-Lymphoid Leukemia Protein
1
2017
70
0.030
Why?
Imidazoles
1
2017
234
0.030
Why?
Mice, Inbred BALB C
1
2019
1247
0.030
Why?
Tumor Protein p73
1
2015
14
0.030
Why?
Cholesterol
1
2017
412
0.030
Why?
Receptors, Estrogen
1
2018
426
0.030
Why?
Histone-Lysine N-Methyltransferase
1
2017
124
0.030
Why?
Aurora Kinase A
1
2015
54
0.030
Why?
Piperazines
1
2017
341
0.030
Why?
Immunity, Innate
1
2020
803
0.030
Why?
Complement System Proteins
1
2017
317
0.030
Why?
Survival Rate
1
2019
1869
0.030
Why?
Cell Movement
1
2018
944
0.030
Why?
Genes, Immediate-Early
1
2013
20
0.030
Why?
Protein Conformation
1
2016
861
0.030
Why?
Genes, ras
1
2013
96
0.030
Why?
NIH 3T3 Cells
1
2013
140
0.030
Why?
B-Lymphocytes
1
2018
815
0.030
Why?
Interleukin-1
1
2017
959
0.030
Why?
Liver
1
2020
1839
0.020
Why?
Biomarkers, Tumor
1
2019
1173
0.020
Why?
Chronic Disease
1
2017
1716
0.020
Why?
HEK293 Cells
1
2013
696
0.020
Why?
Prognosis
1
2019
3773
0.020
Why?
Cell Respiration
1
2010
98
0.020
Why?
Glucose Transporter Type 1
1
2010
49
0.020
Why?
Follow-Up Studies
1
2019
4887
0.020
Why?
Daunorubicin
1
2009
26
0.020
Why?
Checkpoint Kinase 2
1
2009
25
0.020
Why?
Nucleic Acid Synthesis Inhibitors
1
2009
16
0.020
Why?
Checkpoint Kinase 1
1
2009
30
0.020
Why?
Ataxia Telangiectasia Mutated Proteins
1
2009
66
0.020
Why?
Caffeine
1
2009
62
0.020
Why?
Coenzymes
1
2008
19
0.020
Why?
Glyceraldehyde-3-Phosphate Dehydrogenases
1
2007
13
0.020
Why?
RNA Caps
1
2007
33
0.020
Why?
Substrate Specificity
1
2008
368
0.020
Why?
Genes, myc
1
2007
49
0.020
Why?
Poly A
1
2007
48
0.020
Why?
Topoisomerase II Inhibitors
1
2007
24
0.020
Why?
DNA Replication
1
2009
227
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2007
286
0.020
Why?
Retrospective Studies
1
2024
14461
0.020
Why?
Recombinant Proteins
1
2008
1304
0.020
Why?
Mass Spectrometry
1
2008
713
0.010
Why?
Infant
1
2017
8975
0.010
Why?
Myocytes, Cardiac
1
2007
499
0.010
Why?
Mutation
1
2013
3710
0.010
Why?
Models, Molecular
1
2007
1487
0.010
Why?
Espinosa's Networks
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