Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joaquin Espinosa

Concepts (328)

Concepts are derived automatically from a person's publications.

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Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Down Syndrome
25
2025
478
7.100
 Why?
Tumor Suppressor Protein p53
16
2025
503
4.230
 Why?
Transcription, Genetic
12
2021
1416
2.140
 Why?
Cyclin-Dependent Kinases
7
2022
126
1.970
 Why?
Neoplasms
10
2025
2454
1.780
 Why?
Transcriptional Activation
6
2023
366
1.620
 Why?
Janus Kinase Inhibitors
2
2024
26
1.620
 Why?
Chromosomes, Human, Pair 21
2
2024
43
1.520
 Why?
Piperidines
2
2024
200
1.450
 Why?
Pyrimidines
3
2024
458
1.370
 Why?
Proteome
4
2024
440
1.360
 Why?
Transcriptome
4
2024
875
1.270
 Why?
Interferons
4
2023
189
1.220
 Why?
Hypoxia
2
2024
1087
0.970
 Why?
Antineoplastic Agents
5
2025
2045
0.950
 Why?
Gene Regulatory Networks
2
2021
280
0.950
 Why?
Immunoglobulins
1
2025
162
0.900
 Why?
Erythropoiesis
1
2024
51
0.890
 Why?
Heme
1
2024
77
0.870
 Why?
Blood-Brain Barrier
1
2025
132
0.860
 Why?
Receptors, Interferon
2
2023
50
0.850
 Why?
Gene Expression Regulation, Neoplastic
8
2021
1327
0.820
 Why?
Protein Phosphatase 2C
1
2022
15
0.810
 Why?
Transcription Factors
9
2023
1645
0.770
 Why?
Molecular Targeted Therapy
1
2025
391
0.750
 Why?
Blood
1
2022
105
0.740
 Why?
Arthritis, Psoriatic
1
2021
20
0.740
 Why?
Cell Death
1
2022
353
0.710
 Why?
Genes, Tumor Suppressor
1
2021
84
0.700
 Why?
Oncogenes
1
2021
110
0.680
 Why?
Proto-Oncogene Proteins c-mdm2
6
2025
63
0.680
 Why?
Databases, Genetic
1
2021
228
0.670
 Why?
Kynurenine
2
2023
113
0.660
 Why?
Trisomy
2
2019
77
0.650
 Why?
Apoptosis
10
2023
2489
0.640
 Why?
Heart Defects, Congenital
2
2025
796
0.630
 Why?
Interferon-alpha
2
2020
194
0.630
 Why?
Signal Transduction
9
2024
4935
0.630
 Why?
Humans
61
2025
129847
0.610
 Why?
Tumor Suppressor Proteins
2
2018
311
0.600
 Why?
Enhancer Elements, Genetic
1
2020
177
0.600
 Why?
Cyclin-Dependent Kinase 8
6
2022
43
0.600
 Why?
Metabolome
1
2021
339
0.580
 Why?
Genomics
1
2021
716
0.500
 Why?
Case-Control Studies
6
2025
3384
0.450
 Why?
Cell Proliferation
6
2023
2378
0.450
 Why?
Cell Line, Tumor
9
2023
3185
0.450
 Why?
Animals
20
2025
35409
0.440
 Why?
Proteomics
4
2025
1058
0.420
 Why?
Hypoxia-Inducible Factor 1, alpha Subunit
3
2024
274
0.420
 Why?
Carcinoma, Squamous Cell
1
2018
628
0.420
 Why?
Cyclins
3
2022
88
0.390
 Why?
Mice
14
2024
16983
0.390
 Why?
Datasets as Topic
2
2022
109
0.360
 Why?
Cell Cycle Proteins
4
2023
583
0.350
 Why?
RNA Polymerase II
4
2019
317
0.340
 Why?
Triple Negative Breast Neoplasms
3
2019
193
0.340
 Why?
Adult
9
2025
35634
0.320
 Why?
Mediator Complex
3
2022
57
0.310
 Why?
Gene Expression Profiling
3
2024
1686
0.290
 Why?
Female
19
2025
68829
0.290
 Why?
Biomarkers
4
2025
3971
0.280
 Why?
Promoter Regions, Genetic
4
2013
1213
0.270
 Why?
Proto-Oncogene Proteins
2
2023
634
0.270
 Why?
Gene Expression Regulation
3
2012
2545
0.270
 Why?
Adolescent
6
2025
20451
0.260
 Why?
Cytokines
5
2024
2022
0.260
 Why?
Cell Differentiation
2
2024
1900
0.250
 Why?
Positive Transcriptional Elongation Factor B
1
2006
29
0.250
 Why?
Cell Cycle
2
2008
583
0.250
 Why?
Cyclin-Dependent Kinase Inhibitor p21
4
2009
117
0.250
 Why?
Lung Neoplasms
1
2018
2344
0.240
 Why?
Phosphorylation
4
2022
1716
0.240
 Why?
Metabolomics
2
2021
652
0.240
 Why?
Male
11
2025
63759
0.230
 Why?
Protein Binding
5
2021
2123
0.230
 Why?
Hemoglobin SC Disease
1
2023
13
0.220
 Why?
Young Adult
4
2025
12467
0.220
 Why?
Erythropoietin
1
2024
88
0.210
 Why?
Homeodomain Proteins
2
2019
493
0.210
 Why?
Oxidative Phosphorylation
1
2024
188
0.210
 Why?
Liposarcoma
1
2023
26
0.210
 Why?
Glutamine
1
2023
100
0.210
 Why?
Cell Line
4
2019
2780
0.210
 Why?
Alzheimer Disease
2
2020
516
0.200
 Why?
Cyclin C
1
2022
2
0.200
 Why?
Eukaryotic Initiation Factor-2
1
2022
26
0.200
 Why?
Child, Preschool
4
2025
10522
0.200
 Why?
Diabetic Neuropathies
1
2023
96
0.200
 Why?
Growth Disorders
1
2022
81
0.200
 Why?
Centrosome
2
2022
64
0.190
 Why?
Gene Silencing
1
2023
190
0.190
 Why?
Cerebellar Neoplasms
1
2023
150
0.190
 Why?
DNA-Binding Proteins
3
2016
1441
0.180
 Why?
Medulloblastoma
1
2023
191
0.180
 Why?
Acetyltransferases
1
2001
21
0.180
 Why?
Stress, Physiological
1
2024
412
0.180
 Why?
Hematopoiesis
2
2021
184
0.180
 Why?
Access to Information
1
2021
47
0.180
 Why?
Doxorubicin
3
2007
329
0.180
 Why?
Janus Kinase 1
1
2020
24
0.180
 Why?
Cilia
2
2022
180
0.180
 Why?
Janus Kinase 2
1
2020
31
0.180
 Why?
Azetidines
1
2020
40
0.170
 Why?
RNA, Messenger
3
2021
2703
0.170
 Why?
Models, Biological
1
2008
1724
0.170
 Why?
Up-Regulation
2
2021
836
0.170
 Why?
Flow Cytometry
2
2019
1160
0.170
 Why?
Insulin-Like Growth Factor I
1
2022
310
0.170
 Why?
Data Mining
1
2021
110
0.170
 Why?
MicroRNAs
2
2018
680
0.170
 Why?
Nuclear Proteins
3
2023
660
0.170
 Why?
Anemia, Sickle Cell
1
2023
253
0.170
 Why?
Eosinophilic Esophagitis
1
2024
318
0.170
 Why?
Quinolinic Acid
1
2019
8
0.160
 Why?
Child
6
2025
20962
0.160
 Why?
Connective Tissue Diseases
1
2020
82
0.160
 Why?
Biosynthetic Pathways
1
2019
24
0.160
 Why?
Heart Diseases
1
2023
352
0.160
 Why?
Indoleamine-Pyrrole 2,3,-Dioxygenase
1
2019
55
0.160
 Why?
Protein Domains
2
2017
254
0.160
 Why?
Coinfection
1
2020
131
0.150
 Why?
Middle Aged
5
2025
31177
0.150
 Why?
Mice, Inbred C57BL
5
2020
5468
0.150
 Why?
Genome, Human
1
2021
393
0.150
 Why?
Calcinosis
1
2020
233
0.150
 Why?
SOXB1 Transcription Factors
1
2019
57
0.150
 Why?
Nedd4 Ubiquitin Protein Ligases
1
2018
15
0.150
 Why?
Transforming Growth Factor beta2
1
2018
35
0.150
 Why?
Forkhead Box Protein O3
1
2018
15
0.150
 Why?
rhoA GTP-Binding Protein
1
2018
88
0.150
 Why?
Epithelial Cells
1
2024
1063
0.140
 Why?
Bacterial Infections
1
2020
234
0.140
 Why?
TOR Serine-Threonine Kinases
1
2021
398
0.140
 Why?
Stem Cell Niche
1
2018
53
0.140
 Why?
Inflammation
2
2020
2748
0.140
 Why?
Receptor, Notch1
1
2018
62
0.140
 Why?
Inpatients
1
2022
477
0.140
 Why?
Cell Survival
1
2021
1086
0.140
 Why?
Hypersensitivity
1
2020
249
0.140
 Why?
Autoimmunity
1
2023
863
0.140
 Why?
Binding Sites
3
2014
1251
0.140
 Why?
Apoptosis Regulatory Proteins
1
2018
182
0.140
 Why?
Leukemia, Biphenotypic, Acute
1
2017
3
0.140
 Why?
Hedgehog Proteins
1
2018
188
0.140
 Why?
Protein Kinase Inhibitors
2
2020
886
0.130
 Why?
Sulfonamides
1
2020
497
0.130
 Why?
T-Lymphocytes
2
2022
1937
0.130
 Why?
Osteosarcoma
1
2017
70
0.130
 Why?
Histidine Kinase
1
2016
34
0.130
 Why?
Antigens
1
2018
356
0.130
 Why?
Exosomes
1
2017
97
0.130
 Why?
Chromatin
4
2016
478
0.130
 Why?
Proteolysis
1
2017
167
0.130
 Why?
Neoplasm Recurrence, Local
2
2019
957
0.130
 Why?
Interferon-gamma
1
2019
773
0.130
 Why?
Adenosine Triphosphatases
1
2016
161
0.120
 Why?
HCT116 Cells
3
2019
76
0.120
 Why?
Colonic Neoplasms
1
2018
241
0.120
 Why?
Autophagy
1
2018
266
0.120
 Why?
Ribosomal Proteins
1
2015
77
0.120
 Why?
Hematopoietic Stem Cells
1
2018
382
0.120
 Why?
Disease Models, Animal
2
2023
4077
0.120
 Why?
Nerve Tissue Proteins
1
2019
569
0.120
 Why?
Phenotype
1
2023
3062
0.110
 Why?
Bone Neoplasms
1
2017
229
0.110
 Why?
Neoplastic Stem Cells
1
2019
378
0.110
 Why?
Azepines
1
2015
88
0.110
 Why?
Gene Expression
1
2019
1465
0.110
 Why?
Repressor Proteins
1
2017
404
0.110
 Why?
Fibroblasts
1
2019
954
0.110
 Why?
Carrier Proteins
1
2018
741
0.110
 Why?
Acetylation
2
2007
244
0.110
 Why?
ets-Domain Protein Elk-1
1
2013
13
0.110
 Why?
Mitogens
1
2013
61
0.110
 Why?
Disease Progression
1
2021
2628
0.100
 Why?
Down-Regulation
1
2015
631
0.100
 Why?
Prospective Studies
1
2025
7158
0.100
 Why?
Extracellular Signal-Regulated MAP Kinases
1
2013
170
0.100
 Why?
Feedback, Physiological
1
2012
76
0.100
 Why?
Tumor Cells, Cultured
3
2019
931
0.090
 Why?
RNA Stability
1
2012
103
0.090
 Why?
Hypertension, Pulmonary
1
2023
1897
0.090
 Why?
Protein Structure, Tertiary
2
2006
844
0.090
 Why?
Sirtuins
1
2010
39
0.080
 Why?
HeLa Cells
3
2013
611
0.080
 Why?
Histones
2
2007
588
0.080
 Why?
Intracellular Signaling Peptides and Proteins
2
2023
443
0.080
 Why?
S Phase
1
2009
75
0.080
 Why?
Diabetes Mellitus, Type 2
1
2023
2444
0.080
 Why?
Protamine Kinase
1
2008
8
0.080
 Why?
Enzyme Activation
2
2008
813
0.080
 Why?
Receptors, Thyroid Hormone
1
2008
21
0.080
 Why?
Hydroxyurea
2
2023
35
0.070
 Why?
RNA
1
2014
877
0.070
 Why?
DNA Topoisomerases, Type II
1
2007
43
0.070
 Why?
Multiprotein Complexes
1
2008
154
0.070
 Why?
Genome-Wide Association Study
2
2025
1326
0.070
 Why?
Formaldehyde
1
2007
59
0.070
 Why?
Radiation, Ionizing
1
2007
77
0.070
 Why?
Protein Kinases
1
2009
318
0.070
 Why?
Glycolysis
2
2024
314
0.070
 Why?
RNA Precursors
1
2007
148
0.060
 Why?
Fluorouracil
1
2007
197
0.060
 Why?
Transcription Factors, TFII
1
2006
40
0.060
 Why?
High Mobility Group Proteins
1
2006
42
0.060
 Why?
Kinetics
2
2007
1645
0.060
 Why?
Transcriptional Elongation Factors
1
2006
36
0.060
 Why?
Breast Neoplasms
1
2018
2104
0.060
 Why?
Transcription Factor TFIIH
1
2006
37
0.060
 Why?
Chromatin Immunoprecipitation
1
2006
132
0.060
 Why?
Protein Transport
1
2007
429
0.060
 Why?
Mice, Knockout
3
2019
2888
0.060
 Why?
Serine
1
2006
137
0.060
 Why?
Glucose
1
2010
1003
0.060
 Why?
Protein Isoforms
1
2006
393
0.060
 Why?
Xenograft Model Antitumor Assays
2
2019
808
0.060
 Why?
Hemoglobin, Sickle
1
2023
18
0.050
 Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2006
954
0.050
 Why?
Glutamates
1
2023
57
0.050
 Why?
Intermediate Filaments
1
2023
27
0.050
 Why?
Activating Transcription Factor 4
1
2023
20
0.050
 Why?
Proteasome Inhibitors
1
2023
42
0.050
 Why?
L-Selectin
1
2023
25
0.050
 Why?
Proline
1
2023
76
0.050
 Why?
Neurofilament Proteins
1
2023
43
0.050
 Why?
Perforin
1
2023
19
0.050
 Why?
Tyrosine
1
2023
223
0.050
 Why?
Patient Acuity
1
2023
45
0.050
 Why?
Proteasome Endopeptidase Complex
1
2023
149
0.050
 Why?
Protein Tyrosine Phosphatases
1
2023
165
0.050
 Why?
Bile Acids and Salts
1
2023
195
0.050
 Why?
Esophagus
1
2024
251
0.050
 Why?
Hemolysis
1
2023
199
0.050
 Why?
Centrioles
1
2022
41
0.050
 Why?
DNA Footprinting
1
2001
33
0.050
 Why?
Neuroimaging
1
2024
279
0.050
 Why?
Cytoskeletal Proteins
1
2022
147
0.050
 Why?
p300-CBP Transcription Factors
1
2001
20
0.050
 Why?
Immunoblotting
1
2001
306
0.040
 Why?
Clonal Evolution
1
2021
39
0.040
 Why?
Histone Acetyltransferases
1
2001
61
0.040
 Why?
Germ-Line Mutation
1
2020
140
0.040
 Why?
Toll-Like Receptors
1
2020
179
0.040
 Why?
Heterozygote
1
2020
271
0.040
 Why?
Cells, Cultured
2
2018
4102
0.040
 Why?
Interferon Type I
1
2020
139
0.040
 Why?
Genetic Testing
1
2022
422
0.040
 Why?
Vesiculovirus
1
2019
16
0.040
 Why?
Microtubules
1
2022
264
0.040
 Why?
Purines
1
2020
172
0.040
 Why?
Antigens, Neoplasm
1
2022
308
0.040
 Why?
Drosophila melanogaster
1
2001
211
0.040
 Why?
Immunotherapy
1
2024
596
0.040
 Why?
Immunotherapy, Adoptive
1
2022
300
0.040
 Why?
Heart
1
2023
645
0.040
 Why?
STAT1 Transcription Factor
1
2019
70
0.040
 Why?
Nanog Homeobox Protein
1
2019
13
0.040
 Why?
Risk Factors
2
2025
9801
0.040
 Why?
DNA
1
2006
1406
0.040
 Why?
Myelopoiesis
1
2018
7
0.040
 Why?
Lymphopoiesis
1
2018
26
0.040
 Why?
Recombinant Fusion Proteins
1
2001
650
0.040
 Why?
Mice, 129 Strain
1
2018
87
0.040
 Why?
Mice, SCID
1
2019
350
0.040
 Why?
MCF-7 Cells
1
2018
114
0.040
 Why?
Receptors, Growth Factor
1
2017
55
0.040
 Why?
Amyloid beta-Peptides
1
2020
211
0.040
 Why?
Polymorphism, Single Nucleotide
1
2025
2062
0.030
 Why?
Pyrazoles
1
2020
403
0.030
 Why?
Ubiquitin-Conjugating Enzymes
1
2017
13
0.030
 Why?
Mice, Inbred NOD
1
2019
587
0.030
 Why?
Interleukin-1 Receptor-Associated Kinases
1
2017
27
0.030
 Why?
CD8-Positive T-Lymphocytes
1
2023
855
0.030
 Why?
Genetic Predisposition to Disease
1
2025
2271
0.030
 Why?
CD4-Positive T-Lymphocytes
1
2023
1058
0.030
 Why?
Neoplasm Metastasis
1
2019
610
0.030
 Why?
Host-Pathogen Interactions
1
2019
355
0.030
 Why?
Mitosis
1
2017
180
0.030
 Why?
Myeloid-Lymphoid Leukemia Protein
1
2017
70
0.030
 Why?
Imidazoles
1
2017
235
0.030
 Why?
Mice, Inbred BALB C
1
2019
1248
0.030
 Why?
Tumor Protein p73
1
2015
14
0.030
 Why?
Cholesterol
1
2017
412
0.030
 Why?
Receptors, Estrogen
1
2018
422
0.030
 Why?
Histone-Lysine N-Methyltransferase
1
2017
124
0.030
 Why?
Aurora Kinase A
1
2015
53
0.030
 Why?
Piperazines
1
2017
339
0.030
 Why?
Immunity, Innate
1
2020
804
0.030
 Why?
Complement System Proteins
1
2017
319
0.030
 Why?
Survival Rate
1
2019
1872
0.030
 Why?
Cell Movement
1
2018
950
0.030
 Why?
Genes, Immediate-Early
1
2013
19
0.030
 Why?
Protein Conformation
1
2016
861
0.030
 Why?
Genes, ras
1
2013
95
0.030
 Why?
NIH 3T3 Cells
1
2013
140
0.030
 Why?
B-Lymphocytes
1
2018
816
0.030
 Why?
Interleukin-1
1
2017
956
0.020
 Why?
Liver
1
2020
1839
0.020
 Why?
Biomarkers, Tumor
1
2019
1161
0.020
 Why?
Chronic Disease
1
2017
1724
0.020
 Why?
HEK293 Cells
1
2013
697
0.020
 Why?
Prognosis
1
2019
3773
0.020
 Why?
Cell Respiration
1
2010
98
0.020
 Why?
Glucose Transporter Type 1
1
2010
50
0.020
 Why?
Follow-Up Studies
1
2019
4896
0.020
 Why?
Daunorubicin
1
2009
26
0.020
 Why?
Checkpoint Kinase 2
1
2009
25
0.020
 Why?
Nucleic Acid Synthesis Inhibitors
1
2009
16
0.020
 Why?
Checkpoint Kinase 1
1
2009
29
0.020
 Why?
Ataxia Telangiectasia Mutated Proteins
1
2009
65
0.020
 Why?
Caffeine
1
2009
62
0.020
 Why?
Coenzymes
1
2008
20
0.020
 Why?
Glyceraldehyde-3-Phosphate Dehydrogenases
1
2007
13
0.020
 Why?
RNA Caps
1
2007
33
0.020
 Why?
Substrate Specificity
1
2008
371
0.020
 Why?
Genes, myc
1
2007
47
0.020
 Why?
Poly A
1
2007
48
0.020
 Why?
DNA Replication
1
2009
225
0.020
 Why?
Topoisomerase II Inhibitors
1
2007
24
0.020
 Why?
Gene Expression Regulation, Enzymologic
1
2007
284
0.020
 Why?
Retrospective Studies
1
2024
14553
0.020
 Why?
Recombinant Proteins
1
2008
1311
0.010
 Why?
Mass Spectrometry
1
2008
717
0.010
 Why?
Infant
1
2017
9018
0.010
 Why?
Myocytes, Cardiac
1
2007
499
0.010
 Why?
Mutation
1
2013
3706
0.010
 Why?
Models, Molecular
1
2007
1488
0.010
 Why?
Espinosa's Networks
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Concepts Expand Description
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Physical Neighbors Expand Description
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