Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joaquin Espinosa

Concepts (304)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Down Syndrome
18
2023
336
5.150
Why?
Tumor Suppressor Protein p53
14
2023
449
3.630
Why?
Transcription, Genetic
11
2021
1310
2.200
Why?
Cyclin-Dependent Kinases
7
2022
110
2.110
Why?
Transcriptional Activation
6
2023
340
1.720
Why?
Neoplasms
9
2023
2118
1.620
Why?
Proteome
3
2022
345
1.340
Why?
Interferons
4
2023
152
1.330
Why?
Transcriptome
2
2022
736
1.070
Why?
Gene Regulatory Networks
2
2021
231
1.040
Why?
Gene Expression Regulation, Neoplastic
8
2021
1147
0.910
Why?
Receptors, Interferon
2
2023
47
0.890
Why?
Protein Phosphatase 2C
1
2022
14
0.860
Why?
Transcription Factors
8
2023
1528
0.790
Why?
Janus Kinase Inhibitors
1
2021
10
0.780
Why?
Blood
1
2022
97
0.780
Why?
Arthritis, Psoriatic
1
2021
16
0.780
Why?
Cell Death
1
2022
326
0.750
Why?
Genes, Tumor Suppressor
1
2021
78
0.740
Why?
Pyrimidines
2
2021
376
0.730
Why?
Oncogenes
1
2021
104
0.720
Why?
Kynurenine
2
2023
80
0.710
Why?
Databases, Genetic
1
2021
208
0.710
Why?
Piperidines
1
2021
163
0.700
Why?
Trisomy
2
2019
68
0.690
Why?
Chromosomes, Human, Pair 21
1
2019
31
0.680
Why?
Apoptosis
10
2023
2377
0.670
Why?
Interferon-alpha
2
2020
186
0.670
Why?
Enhancer Elements, Genetic
1
2020
150
0.640
Why?
Tumor Suppressor Proteins
2
2018
286
0.640
Why?
Cyclin-Dependent Kinase 8
6
2022
38
0.640
Why?
Metabolome
1
2021
287
0.620
Why?
Antineoplastic Agents
4
2023
1893
0.560
Why?
Heart Defects, Congenital
1
2023
659
0.550
Why?
Genomics
1
2021
646
0.540
Why?
Humans
51
2023
115589
0.510
Why?
Cell Line, Tumor
9
2023
2751
0.500
Why?
Cell Proliferation
6
2023
2194
0.490
Why?
Hypoxia
1
2021
937
0.490
Why?
Proto-Oncogene Proteins c-mdm2
5
2023
57
0.480
Why?
Carcinoma, Squamous Cell
1
2018
577
0.440
Why?
Datasets as Topic
2
2022
99
0.380
Why?
RNA Polymerase II
4
2019
283
0.370
Why?
Triple Negative Breast Neoplasms
3
2019
157
0.370
Why?
Animals
17
2023
32102
0.370
Why?
Mice
13
2023
15052
0.360
Why?
Mediator Complex
3
2022
52
0.320
Why?
Proteomics
3
2023
859
0.310
Why?
Proto-Oncogene Proteins
2
2023
609
0.280
Why?
Signal Transduction
7
2023
4541
0.280
Why?
Case-Control Studies
3
2023
3022
0.270
Why?
Positive Transcriptional Elongation Factor B
1
2006
22
0.270
Why?
Cell Cycle
2
2008
546
0.260
Why?
Gene Expression Regulation
2
2012
2353
0.260
Why?
Lung Neoplasms
1
2018
2207
0.260
Why?
Metabolomics
2
2021
538
0.260
Why?
Phosphorylation
4
2022
1571
0.260
Why?
Cytokines
4
2020
1853
0.250
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
2
2021
249
0.240
Why?
Hemoglobin SC Disease
1
2023
15
0.230
Why?
Cyclins
2
2022
79
0.230
Why?
Alzheimer Disease
2
2020
438
0.230
Why?
Homeodomain Proteins
2
2019
465
0.230
Why?
Liposarcoma
1
2023
26
0.220
Why?
Glutamine
1
2023
91
0.220
Why?
Cell Cycle Proteins
3
2023
553
0.220
Why?
Cell Line
4
2019
2651
0.220
Why?
Protein Binding
4
2021
1917
0.220
Why?
Cyclin-Dependent Kinase Inhibitor p21
3
2009
107
0.220
Why?
Cyclin C
1
2022
2
0.220
Why?
Eukaryotic Initiation Factor-2
1
2022
23
0.210
Why?
Diabetic Neuropathies
1
2023
79
0.210
Why?
Growth Disorders
1
2022
78
0.210
Why?
Centrosome
2
2022
59
0.210
Why?
Biomarkers
3
2023
3467
0.200
Why?
Cerebellar Neoplasms
1
2023
131
0.200
Why?
DNA-Binding Proteins
3
2016
1316
0.200
Why?
Gene Silencing
1
2023
175
0.200
Why?
Medulloblastoma
1
2023
172
0.200
Why?
Doxorubicin
3
2007
290
0.190
Why?
Hematopoiesis
2
2021
173
0.190
Why?
Cilia
2
2022
162
0.190
Why?
Access to Information
1
2021
50
0.190
Why?
Janus Kinase 1
1
2020
23
0.190
Why?
Janus Kinase 2
1
2020
31
0.180
Why?
Azetidines
1
2020
31
0.180
Why?
MicroRNAs
2
2018
607
0.180
Why?
RNA, Messenger
3
2021
2574
0.180
Why?
Flow Cytometry
2
2019
1083
0.180
Why?
Models, Biological
1
2008
1646
0.180
Why?
Insulin-Like Growth Factor I
1
2022
281
0.180
Why?
Anemia, Sickle Cell
1
2023
217
0.180
Why?
Up-Regulation
2
2021
820
0.180
Why?
Nuclear Proteins
3
2023
594
0.180
Why?
Data Mining
1
2021
100
0.180
Why?
Connective Tissue Diseases
1
2020
71
0.170
Why?
Quinolinic Acid
1
2019
7
0.170
Why?
Heart Diseases
1
2023
330
0.170
Why?
Mice, Inbred C57BL
5
2020
4773
0.170
Why?
Biosynthetic Pathways
1
2019
19
0.170
Why?
Indoleamine-Pyrrole 2,3,-Dioxygenase
1
2019
44
0.170
Why?
Protein Domains
2
2017
209
0.170
Why?
Gene Expression Profiling
2
2021
1536
0.170
Why?
Coinfection
1
2020
120
0.160
Why?
Genome, Human
1
2021
352
0.160
Why?
SOXB1 Transcription Factors
1
2019
60
0.160
Why?
Nedd4 Ubiquitin Protein Ligases
1
2018
13
0.160
Why?
Inflammation
2
2020
2499
0.160
Why?
rhoA GTP-Binding Protein
1
2018
75
0.160
Why?
Inpatients
1
2022
380
0.160
Why?
Transforming Growth Factor beta2
1
2018
31
0.160
Why?
Forkhead Box Protein O3
1
2018
13
0.150
Why?
Stem Cell Niche
1
2018
43
0.150
Why?
TOR Serine-Threonine Kinases
1
2021
362
0.150
Why?
Calcinosis
1
2020
242
0.150
Why?
Bacterial Infections
1
2020
222
0.150
Why?
Promoter Regions, Genetic
3
2013
1122
0.150
Why?
Receptor, Notch1
1
2018
59
0.150
Why?
Cell Survival
1
2021
1024
0.150
Why?
Female
12
2021
59913
0.150
Why?
Autoimmunity
1
2023
822
0.150
Why?
T-Lymphocytes
2
2022
1756
0.150
Why?
Adult
5
2021
30719
0.140
Why?
Apoptosis Regulatory Proteins
1
2018
174
0.140
Why?
Sulfonamides
1
2020
447
0.140
Why?
Protein Kinase Inhibitors
2
2020
790
0.140
Why?
Hedgehog Proteins
1
2018
172
0.140
Why?
Leukemia, Biphenotypic, Acute
1
2017
3
0.140
Why?
Hypersensitivity
1
2020
260
0.140
Why?
Antigens
1
2018
323
0.140
Why?
Osteosarcoma
1
2017
66
0.140
Why?
Neoplasm Recurrence, Local
2
2019
863
0.140
Why?
Histidine Kinase
1
2016
33
0.140
Why?
Exosomes
1
2017
92
0.140
Why?
Proteolysis
1
2017
145
0.130
Why?
Interferon-gamma
1
2019
726
0.130
Why?
Disease Models, Animal
2
2023
3580
0.130
Why?
Colonic Neoplasms
1
2018
222
0.130
Why?
Cell Differentiation
1
2023
1700
0.130
Why?
Autophagy
1
2018
236
0.130
Why?
Adenosine Triphosphatases
1
2016
155
0.130
Why?
HCT116 Cells
3
2019
69
0.130
Why?
Ribosomal Proteins
1
2015
70
0.130
Why?
Hematopoietic Stem Cells
1
2018
346
0.130
Why?
Phenotype
1
2023
2829
0.130
Why?
Neoplastic Stem Cells
1
2019
331
0.130
Why?
Bone Neoplasms
1
2017
194
0.120
Why?
Nerve Tissue Proteins
1
2019
535
0.120
Why?
Fibroblasts
1
2019
839
0.120
Why?
Azepines
1
2015
74
0.120
Why?
Repressor Proteins
1
2017
369
0.120
Why?
Gene Expression
1
2019
1436
0.120
Why?
Carrier Proteins
1
2018
701
0.120
Why?
Disease Progression
1
2021
2418
0.110
Why?
ets-Domain Protein Elk-1
1
2013
13
0.110
Why?
Middle Aged
4
2021
26998
0.110
Why?
Mitogens
1
2013
58
0.110
Why?
Down-Regulation
1
2015
601
0.110
Why?
Binding Sites
2
2014
1177
0.110
Why?
Extracellular Signal-Regulated MAP Kinases
1
2013
157
0.110
Why?
Feedback, Physiological
1
2012
73
0.100
Why?
Hypertension, Pulmonary
1
2023
1749
0.100
Why?
Tumor Cells, Cultured
3
2019
850
0.100
Why?
RNA Stability
1
2012
93
0.100
Why?
Chromatin
3
2016
429
0.100
Why?
Diabetes Mellitus, Type 2
1
2023
2098
0.090
Why?
Sirtuins
1
2010
32
0.090
Why?
Intracellular Signaling Peptides and Proteins
2
2023
388
0.090
Why?
S Phase
1
2009
69
0.080
Why?
Male
5
2021
55949
0.080
Why?
Protamine Kinase
1
2008
8
0.080
Why?
Receptors, Thyroid Hormone
1
2008
20
0.080
Why?
Enzyme Activation
2
2008
793
0.080
Why?
Young Adult
2
2021
10470
0.080
Why?
Hydroxyurea
2
2023
30
0.080
Why?
RNA
1
2014
819
0.080
Why?
Formaldehyde
1
2007
47
0.070
Why?
Multiprotein Complexes
1
2008
145
0.070
Why?
DNA Topoisomerases, Type II
1
2007
45
0.070
Why?
Radiation, Ionizing
1
2007
73
0.070
Why?
Protein Kinases
1
2009
306
0.070
Why?
Acetylation
1
2007
212
0.070
Why?
RNA Precursors
1
2007
136
0.070
Why?
Fluorouracil
1
2007
151
0.070
Why?
Breast Neoplasms
1
2018
1872
0.070
Why?
Mice, Knockout
3
2019
2604
0.070
Why?
Kinetics
2
2007
1569
0.070
Why?
Transcription Factors, TFII
1
2006
37
0.070
Why?
Transcription Factor TFIIH
1
2006
33
0.070
Why?
Transcriptional Elongation Factors
1
2006
33
0.070
Why?
High Mobility Group Proteins
1
2006
50
0.070
Why?
Protein Transport
1
2007
400
0.060
Why?
Chromatin Immunoprecipitation
1
2006
129
0.060
Why?
Serine
1
2006
125
0.060
Why?
Glucose
1
2010
904
0.060
Why?
Protein Isoforms
1
2006
339
0.060
Why?
Xenograft Model Antitumor Assays
2
2019
704
0.060
Why?
Hemoglobin, Sickle
1
2023
14
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2006
930
0.060
Why?
Glutamates
1
2023
59
0.060
Why?
Activating Transcription Factor 4
1
2023
18
0.060
Why?
Proteasome Inhibitors
1
2023
40
0.060
Why?
Intermediate Filaments
1
2023
46
0.060
Why?
Protein Structure, Tertiary
1
2006
804
0.060
Why?
Neurofilament Proteins
1
2023
34
0.050
Why?
Proline
1
2023
72
0.050
Why?
L-Selectin
1
2023
25
0.050
Why?
Perforin
1
2023
19
0.050
Why?
Tyrosine
1
2023
219
0.050
Why?
Proteasome Endopeptidase Complex
1
2023
136
0.050
Why?
Patient Acuity
1
2023
42
0.050
Why?
Protein Tyrosine Phosphatases
1
2023
147
0.050
Why?
Hemolysis
1
2023
146
0.050
Why?
Bile Acids and Salts
1
2023
172
0.050
Why?
Histones
1
2007
540
0.050
Why?
Centrioles
1
2022
35
0.050
Why?
Cytoskeletal Proteins
1
2022
145
0.050
Why?
Clonal Evolution
1
2021
27
0.050
Why?
Immunotherapy, Adoptive
1
2022
194
0.050
Why?
Antigens, Neoplasm
1
2022
223
0.050
Why?
Genetic Testing
1
2022
382
0.040
Why?
Heterozygote
1
2020
252
0.040
Why?
Germ-Line Mutation
1
2020
131
0.040
Why?
Microtubules
1
2022
238
0.040
Why?
Vesiculovirus
1
2019
9
0.040
Why?
Cells, Cultured
2
2018
3914
0.040
Why?
Toll-Like Receptors
1
2020
166
0.040
Why?
Interferon Type I
1
2020
129
0.040
Why?
HeLa Cells
2
2013
567
0.040
Why?
Purines
1
2020
159
0.040
Why?
Heart
1
2023
608
0.040
Why?
STAT1 Transcription Factor
1
2019
64
0.040
Why?
Nanog Homeobox Protein
1
2019
11
0.040
Why?
DNA
1
2006
1356
0.040
Why?
Myelopoiesis
1
2018
6
0.040
Why?
Child
3
2023
18489
0.040
Why?
Lymphopoiesis
1
2018
24
0.040
Why?
Mice, 129 Strain
1
2018
77
0.040
Why?
Mice, SCID
1
2019
321
0.040
Why?
MCF-7 Cells
1
2018
105
0.040
Why?
Amyloid beta-Peptides
1
2020
191
0.040
Why?
CD8-Positive T-Lymphocytes
1
2023
693
0.040
Why?
Receptors, Growth Factor
1
2017
49
0.040
Why?
Pyrazoles
1
2020
362
0.040
Why?
Ubiquitin-Conjugating Enzymes
1
2017
9
0.040
Why?
Mice, Inbred NOD
1
2019
560
0.040
Why?
Interleukin-1 Receptor-Associated Kinases
1
2017
21
0.040
Why?
CD4-Positive T-Lymphocytes
1
2023
965
0.040
Why?
Neoplasm Metastasis
1
2019
526
0.030
Why?
Host-Pathogen Interactions
1
2019
296
0.030
Why?
Mitosis
1
2017
164
0.030
Why?
Genome-Wide Association Study
1
2022
1217
0.030
Why?
Myeloid-Lymphoid Leukemia Protein
1
2017
63
0.030
Why?
Imidazoles
1
2017
217
0.030
Why?
Mice, Inbred BALB C
1
2019
1168
0.030
Why?
Histone-Lysine N-Methyltransferase
1
2017
96
0.030
Why?
Cholesterol
1
2017
369
0.030
Why?
Receptors, Estrogen
1
2018
372
0.030
Why?
Tumor Protein p73
1
2015
15
0.030
Why?
Immunity, Innate
1
2020
731
0.030
Why?
Aurora Kinase A
1
2015
51
0.030
Why?
Piperazines
1
2017
314
0.030
Why?
Complement System Proteins
1
2017
288
0.030
Why?
Survival Rate
1
2019
1650
0.030
Why?
Cell Movement
1
2018
867
0.030
Why?
Genes, Immediate-Early
1
2013
18
0.030
Why?
Protein Conformation
1
2016
822
0.030
Why?
Genes, ras
1
2013
91
0.030
Why?
NIH 3T3 Cells
1
2013
137
0.030
Why?
B-Lymphocytes
1
2018
773
0.030
Why?
Liver
1
2020
1690
0.030
Why?
Adolescent
2
2023
17890
0.030
Why?
Biomarkers, Tumor
1
2019
1048
0.030
Why?
Interleukin-1
1
2017
971
0.030
Why?
Chronic Disease
1
2017
1598
0.020
Why?
HEK293 Cells
1
2013
602
0.020
Why?
Prognosis
1
2019
3339
0.020
Why?
Follow-Up Studies
1
2019
4440
0.020
Why?
Cell Respiration
1
2010
74
0.020
Why?
Glucose Transporter Type 1
1
2010
42
0.020
Why?
Daunorubicin
1
2009
24
0.020
Why?
Checkpoint Kinase 2
1
2009
21
0.020
Why?
Checkpoint Kinase 1
1
2009
28
0.020
Why?
Nucleic Acid Synthesis Inhibitors
1
2009
18
0.020
Why?
Ataxia Telangiectasia Mutated Proteins
1
2009
63
0.020
Why?
Coenzymes
1
2008
16
0.020
Why?
Caffeine
1
2009
58
0.020
Why?
Glycolysis
1
2010
224
0.020
Why?
Glyceraldehyde-3-Phosphate Dehydrogenases
1
2007
14
0.020
Why?
RNA Caps
1
2007
31
0.020
Why?
Substrate Specificity
1
2008
357
0.020
Why?
Genes, myc
1
2007
47
0.020
Why?
DNA Replication
1
2009
203
0.020
Why?
Poly A
1
2007
46
0.020
Why?
Topoisomerase II Inhibitors
1
2007
23
0.020
Why?
Risk Factors
1
2020
8697
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2007
274
0.020
Why?
Mass Spectrometry
1
2008
645
0.020
Why?
Recombinant Proteins
1
2008
1243
0.020
Why?
Infant
1
2017
7979
0.010
Why?
Child, Preschool
1
2017
9133
0.010
Why?
Myocytes, Cardiac
1
2007
457
0.010
Why?
Mutation
1
2013
3364
0.010
Why?
Models, Molecular
1
2007
1390
0.010
Why?
Espinosa's Networks
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