Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christopher Link

Concepts (405)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Caenorhabditis elegans
47
2019
330
5.870
Why?
Amyloid beta-Peptides
24
2021
251
4.060
Why?
Caenorhabditis elegans Proteins
20
2019
209
2.960
Why?
Alzheimer Disease
17
2023
639
1.820
Why?
Astrocytes
3
2024
230
1.800
Why?
Peptide Fragments
10
2021
698
1.510
Why?
RNA, Double-Stranded
6
2023
53
1.340
Why?
Neurons
11
2026
1672
1.320
Why?
Animals, Genetically Modified
27
2018
248
1.250
Why?
Induced Pluripotent Stem Cells
2
2024
277
1.090
Why?
DNA-Binding Proteins
9
2023
1488
1.090
Why?
RNA-Binding Proteins
4
2019
451
0.870
Why?
Coculture Techniques
1
2024
247
0.790
Why?
Cell Differentiation
2
2024
2054
0.790
Why?
RNA, Helminth
5
2019
18
0.760
Why?
C9orf72 Protein
5
2019
11
0.760
Why?
Amyotrophic Lateral Sclerosis
7
2023
96
0.720
Why?
Heat-Shock Response
2
2019
78
0.720
Why?
Animals
66
2026
38417
0.650
Why?
Cell Nucleus
3
2019
589
0.630
Why?
Gene Knockdown Techniques
3
2021
334
0.610
Why?
Heat-Shock Proteins
7
2010
140
0.600
Why?
Aging
10
2023
1992
0.590
Why?
Green Fluorescent Proteins
10
2019
407
0.580
Why?
Brain
10
2026
3009
0.570
Why?
Disease Models, Animal
18
2026
4605
0.570
Why?
Chromosomal Proteins, Non-Histone
2
2019
130
0.550
Why?
Neurodegenerative Diseases
4
2022
144
0.530
Why?
Chromosomes, Human, Pair 21
1
2018
43
0.530
Why?
Endosomes
1
2018
140
0.510
Why?
Transcriptome
4
2021
1059
0.510
Why?
Trisomy
1
2018
80
0.510
Why?
Longevity
7
2021
178
0.500
Why?
Oxidative Stress
12
2012
1368
0.480
Why?
Transcription, Genetic
5
2019
1456
0.480
Why?
Down Syndrome
2
2026
526
0.480
Why?
Proteins
5
2021
1024
0.460
Why?
Receptor, Insulin
3
2010
93
0.430
Why?
Genes, Helminth
4
2018
30
0.410
Why?
Models, Animal
2
2018
394
0.400
Why?
Paralysis
3
2010
69
0.400
Why?
RNA Stability
1
2014
108
0.400
Why?
Cytokines
1
2021
2087
0.390
Why?
Gene Expression
6
2016
1481
0.380
Why?
Immunity, Innate
1
2019
840
0.380
Why?
Plant Extracts
3
2010
191
0.380
Why?
Drosophila melanogaster
4
2017
241
0.360
Why?
Cells, Cultured
6
2024
4170
0.360
Why?
Gene Expression Profiling
4
2021
1794
0.360
Why?
Molecular Chaperones
2
2005
199
0.350
Why?
Gene Expression Regulation
6
2016
2625
0.350
Why?
Luminescent Proteins
5
2015
187
0.340
Why?
Autophagy
2
2019
291
0.330
Why?
Transgenes
6
2016
190
0.320
Why?
Peptides
3
2019
1003
0.320
Why?
Cell Death
1
2012
383
0.310
Why?
Carrier Proteins
2
2016
731
0.300
Why?
RNA Interference
7
2018
477
0.290
Why?
Prealbumin
2
2016
38
0.280
Why?
Sequence Analysis, RNA
4
2021
443
0.280
Why?
Stress, Physiological
5
2021
445
0.270
Why?
Heat-Shock Proteins, Small
1
2007
2
0.270
Why?
Sleep
2
2026
895
0.270
Why?
Alternative Splicing
4
2018
248
0.260
Why?
Tumor Necrosis Factor-alpha
2
2021
1225
0.260
Why?
Computational Biology
2
2021
677
0.250
Why?
Hemolysin Proteins
2
2018
36
0.250
Why?
Genes, Reporter
3
2016
278
0.250
Why?
Intracellular Signaling Peptides and Proteins
2
2026
459
0.240
Why?
Hydrogen Sulfide
3
2021
47
0.240
Why?
Synapses
1
2010
448
0.230
Why?
Endotoxins
2
2018
217
0.230
Why?
Humans
37
2026
147306
0.230
Why?
Virus Activation
1
2026
97
0.230
Why?
Herpes Simplex
1
2026
102
0.220
Why?
Frontal Lobe
2
2017
161
0.220
Why?
Herpesvirus 1, Human
1
2026
87
0.220
Why?
Gene Deletion
2
2018
392
0.220
Why?
Endoplasmic Reticulum
2
2019
269
0.220
Why?
Mutation
10
2017
4130
0.220
Why?
Rats
5
2019
5613
0.210
Why?
eIF-2 Kinase
1
2024
28
0.210
Why?
Muscle Proteins
1
2026
244
0.210
Why?
Mice, Inbred C57BL
7
2026
6042
0.210
Why?
Oligonucleotide Array Sequence Analysis
3
2003
751
0.210
Why?
Electrodes
1
2024
111
0.200
Why?
Nerve Tissue Proteins
2
2024
597
0.200
Why?
Organisms, Genetically Modified
1
2003
14
0.190
Why?
Primary Cell Culture
2
2021
173
0.190
Why?
alpha-Crystallin B Chain
1
2003
24
0.190
Why?
Mice, Knockout
4
2024
3153
0.190
Why?
Wakefulness
1
2024
171
0.190
Why?
Brain Chemistry
1
2003
121
0.190
Why?
Blood-Brain Barrier
1
2024
167
0.190
Why?
Transfection
4
2012
930
0.180
Why?
Amino Acid Sequence
5
2008
2134
0.180
Why?
Protein Aggregation, Pathological
2
2019
18
0.180
Why?
Cell Line
4
2019
2832
0.180
Why?
Microscopy, Fluorescence
4
2010
409
0.180
Why?
Sleep Deprivation
1
2024
207
0.180
Why?
Regulatory Sequences, Nucleic Acid
1
2002
93
0.180
Why?
Sleep Wake Disorders
1
2026
315
0.180
Why?
Immunoblotting
4
2019
296
0.170
Why?
Dipeptides
2
2019
56
0.170
Why?
Complement C1q
1
2021
32
0.170
Why?
Bacterial Proteins
3
2018
977
0.170
Why?
Mice
15
2026
18493
0.170
Why?
Signal Transduction
4
2016
5272
0.170
Why?
Amino Acids, Sulfur
1
2021
8
0.170
Why?
Interleukin-1alpha
1
2021
57
0.170
Why?
Cystathionine gamma-Lyase
1
2021
13
0.170
Why?
Activating Transcription Factor 4
1
2021
22
0.170
Why?
Diet, High-Fat
1
2022
267
0.160
Why?
Amyloidosis
1
2001
45
0.160
Why?
DNA Repeat Expansion
2
2017
10
0.160
Why?
Repetitive Sequences, Nucleic Acid
2
2019
118
0.160
Why?
Helminth Proteins
1
2000
24
0.160
Why?
Staining and Labeling
1
2001
153
0.160
Why?
Molecular Sequence Data
5
2007
2886
0.160
Why?
RNA
2
2018
916
0.160
Why?
Embryo, Mammalian
2
2018
234
0.150
Why?
Hippocampus
2
2018
989
0.150
Why?
Brain Injuries, Traumatic
1
2026
462
0.150
Why?
Frontotemporal Lobar Degeneration
2
2017
18
0.150
Why?
Mitochondria
3
2016
1000
0.150
Why?
RNA, Small Interfering
2
2019
643
0.150
Why?
Ultracentrifugation
2
2017
51
0.150
Why?
Viruses
1
2021
166
0.150
Why?
Glutathione Reductase
1
2019
24
0.140
Why?
Protein Aggregates
2
2019
86
0.140
Why?
Frontotemporal Dementia
2
2016
56
0.140
Why?
Protein-Tyrosine Kinases
1
2002
432
0.140
Why?
Recombinant Fusion Proteins
4
2015
669
0.140
Why?
Proteostasis
1
2019
32
0.140
Why?
Acrylates
1
2018
48
0.140
Why?
Morpholinos
1
2018
30
0.140
Why?
Sphingomyelin Phosphodiesterase
1
2018
27
0.140
Why?
Heterochromatin
1
2019
68
0.140
Why?
Phosphatidylinositol 3-Kinases
1
2000
383
0.140
Why?
Protein Structure, Secondary
1
2019
372
0.130
Why?
Blotting, Western
5
2017
1186
0.130
Why?
RNA Editing
1
2018
26
0.130
Why?
Vesicular Transport Proteins
1
2018
85
0.130
Why?
Cytoplasmic Granules
1
2018
60
0.130
Why?
Up-Regulation
3
2009
848
0.130
Why?
Inclusion Bodies
3
2016
27
0.130
Why?
Huntingtin Protein
1
2017
13
0.130
Why?
Behavior, Animal
3
2016
530
0.130
Why?
Artificial Intelligence
1
2022
389
0.130
Why?
Phenotype
4
2019
3216
0.130
Why?
Frailty
1
2021
206
0.130
Why?
Autopsy
1
2017
96
0.130
Why?
Glutathione
1
2019
370
0.120
Why?
Saccharomyces cerevisiae
2
2019
585
0.120
Why?
Cognitive Dysfunction
1
2023
479
0.120
Why?
Heterozygote
1
2017
317
0.120
Why?
Animals, Newborn
1
2019
915
0.120
Why?
Inflammation Mediators
1
2019
507
0.120
Why?
MAP Kinase Kinase Kinases
1
2016
70
0.120
Why?
Phosphorylation
2
2018
1721
0.120
Why?
Cell Survival
1
2019
1111
0.120
Why?
Wound Healing
1
2018
361
0.110
Why?
Guanine Nucleotide Exchange Factors
1
2016
64
0.110
Why?
Intestines
1
2018
356
0.110
Why?
Transcriptional Activation
1
2017
372
0.110
Why?
Enzyme Inhibitors
1
2018
822
0.110
Why?
Mitogen-Activated Protein Kinases
1
2016
288
0.110
Why?
tau Proteins
2
2006
108
0.110
Why?
Diet
2
2021
1284
0.110
Why?
Conserved Sequence
2
2007
244
0.110
Why?
Chromatin
1
2018
561
0.100
Why?
RNA Polymerase II
1
2017
350
0.100
Why?
Protein Processing, Post-Translational
1
2016
482
0.100
Why?
Transcription Factors
4
2011
1747
0.100
Why?
Proteasome Endopeptidase Complex
1
2014
156
0.100
Why?
Adaptor Proteins, Signal Transducing
2
2009
430
0.100
Why?
Cerebellum
1
2015
227
0.100
Why?
Neuroprotective Agents
2
2012
149
0.100
Why?
Repressor Proteins
1
2016
429
0.090
Why?
Glutathione Transferase
2
2003
92
0.090
Why?
Microscopy, Confocal
2
2012
322
0.090
Why?
Cricetulus
2
2012
118
0.090
Why?
Shab Potassium Channels
1
2012
20
0.090
Why?
Adaptor Proteins, Vesicular Transport
1
2012
46
0.090
Why?
Gastrointestinal Microbiome
1
2020
773
0.090
Why?
Cricetinae
2
2012
305
0.090
Why?
Neurites
1
2012
51
0.090
Why?
Caloric Restriction
2
2010
133
0.090
Why?
Electroencephalography
2
2026
570
0.090
Why?
Molecular Targeted Therapy
1
2014
444
0.080
Why?
Male
13
2026
73954
0.080
Why?
Sequence Analysis, Protein
2
2008
32
0.080
Why?
Immunohistochemistry
4
2012
1730
0.080
Why?
Promoter Regions, Genetic
3
2010
1253
0.080
Why?
Intercellular Signaling Peptides and Proteins
1
2012
376
0.080
Why?
Protein Structure, Quaternary
1
2010
116
0.080
Why?
Base Sequence
2
2005
2175
0.080
Why?
Enzyme-Linked Immunosorbent Assay
2
2012
849
0.080
Why?
Amyloid beta-Protein Precursor
2
2012
64
0.080
Why?
Fasting
2
2022
280
0.080
Why?
Presenilin-1
2
2012
34
0.080
Why?
Caffeine
1
2010
76
0.080
Why?
Renin
2
2007
33
0.080
Why?
Fertility
1
2011
175
0.080
Why?
HSP70 Heat-Shock Proteins
2
2017
76
0.080
Why?
Sequence Deletion
1
2010
192
0.080
Why?
NADPH Oxidases
2
2007
123
0.080
Why?
Case-Control Studies
1
2017
3660
0.070
Why?
Mutagenesis, Site-Directed
2
2002
377
0.070
Why?
Prenylation
1
2009
3
0.070
Why?
Protein Structure, Tertiary
2
2009
855
0.070
Why?
Neuropeptides
1
2009
75
0.070
Why?
Renin-Angiotensin System
2
2007
80
0.070
Why?
RNA, Messenger
5
2018
2812
0.070
Why?
Antioxidants
2
2021
550
0.070
Why?
Biotinylation
1
2008
37
0.070
Why?
Endocytosis
1
2009
168
0.070
Why?
Genitalia, Male
1
1988
11
0.070
Why?
CHO Cells
1
2008
169
0.070
Why?
Proteomics
2
2005
1205
0.070
Why?
Movement
1
2010
293
0.070
Why?
Antigens, Surface
1
1988
155
0.070
Why?
Muscle, Skeletal
2
2009
1798
0.070
Why?
Fluorescent Antibody Technique
1
2008
365
0.070
Why?
Amino Acid Substitution
1
2008
303
0.060
Why?
Survival Rate
2
2010
2110
0.060
Why?
Oxidation-Reduction
4
2019
1077
0.060
Why?
Ginkgolides
1
2006
4
0.060
Why?
Spironolactone
1
2007
40
0.060
Why?
Lysosomes
1
2007
133
0.060
Why?
Hypertension, Renal
1
2006
15
0.060
Why?
Electrophoresis, Gel, Two-Dimensional
3
2017
110
0.060
Why?
Mineralocorticoid Receptor Antagonists
1
2007
69
0.060
Why?
Protein Biosynthesis
2
2021
452
0.060
Why?
Cardiomegaly
1
2007
175
0.060
Why?
Virus Latency
1
2026
93
0.060
Why?
Isoflavones
1
2005
25
0.060
Why?
Regulatory Factor X Transcription Factors
1
2005
9
0.060
Why?
Solubility
1
2005
240
0.050
Why?
Phytotherapy
1
2005
74
0.050
Why?
DNA
2
2021
1444
0.050
Why?
Ventricular Remodeling
1
2007
283
0.050
Why?
Cell Proliferation
1
2012
2529
0.050
Why?
Cloning, Molecular
1
2005
539
0.050
Why?
DNA Primers
1
2005
505
0.050
Why?
Dementia
1
2009
332
0.050
Why?
Feeding Behavior
1
2010
693
0.050
Why?
Sleep, REM
1
2024
44
0.050
Why?
Protein Binding
2
2002
2249
0.050
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2003
980
0.050
Why?
Genetic Vectors
1
2005
335
0.050
Why?
Models, Genetic
1
2006
536
0.050
Why?
Genome
2
2003
306
0.050
Why?
Aged
3
2017
26516
0.050
Why?
Neurofibrils
1
2003
2
0.050
Why?
Plaque, Amyloid
1
2003
20
0.050
Why?
Saccharomyces cerevisiae Proteins
2
2018
416
0.050
Why?
Gliosis
1
2023
30
0.050
Why?
Body Temperature
1
2024
229
0.050
Why?
Onchocerca volvulus
1
2003
1
0.050
Why?
Reverse Transcriptase Inhibitors
1
2023
88
0.050
Why?
Female
6
2026
80081
0.050
Why?
Models, Biological
2
2007
1772
0.050
Why?
Operon
1
2002
67
0.040
Why?
Liver
2
2021
1916
0.040
Why?
Cell Line, Tumor
1
2010
3565
0.040
Why?
Hyperbaric Oxygenation
1
2002
39
0.040
Why?
Multigene Family
1
2002
210
0.040
Why?
Prion Diseases
1
2001
25
0.040
Why?
Probability
1
2002
309
0.040
Why?
Alkenes
1
2001
7
0.040
Why?
Microscopy, Immunoelectron
1
2001
43
0.040
Why?
Statistics, Nonparametric
1
2002
430
0.040
Why?
Diet Therapy
1
2021
36
0.040
Why?
Benzoates
1
2001
51
0.040
Why?
Species Specificity
1
2002
547
0.040
Why?
Down-Regulation
1
2003
618
0.040
Why?
Hydrogen
1
2021
73
0.040
Why?
Motor Neurons
1
2023
236
0.040
Why?
Lipopolysaccharides
1
2024
863
0.040
Why?
Mice, Transgenic
1
2026
2197
0.040
Why?
Spinal Cord
1
2023
383
0.040
Why?
Methylamines
1
2020
39
0.040
Why?
Nematoda
1
1999
12
0.040
Why?
Muscles
1
2021
330
0.040
Why?
Fibroblast Growth Factors
1
2021
188
0.040
Why?
Insulin
1
2010
2526
0.040
Why?
Maleates
1
2019
5
0.040
Why?
Nuclear Lamina
1
2019
12
0.040
Why?
Sequestosome-1 Protein
1
2019
15
0.040
Why?
Fluorescent Dyes
1
2001
342
0.040
Why?
Recombinant Proteins
1
2002
1371
0.040
Why?
Reproduction
2
2011
212
0.040
Why?
Muscle Cells
1
2019
41
0.040
Why?
alpha-Synuclein
1
2019
47
0.040
Why?
Binding Sites
1
2002
1319
0.040
Why?
Membrane Proteins
1
2005
1171
0.030
Why?
Anxiety
1
2026
1149
0.030
Why?
Dimerization
1
1998
189
0.030
Why?
Proteolysis
1
2019
173
0.030
Why?
Oxidants
2
2012
99
0.030
Why?
Middle Aged
2
2017
36821
0.030
Why?
Ribonucleoproteins
1
2018
90
0.030
Why?
Body Composition
1
2021
694
0.030
Why?
Genetic Variation
1
2002
995
0.030
Why?
Antibodies
1
2019
398
0.030
Why?
Genomics
1
2002
839
0.030
Why?
Hydrogen Peroxide
2
2012
338
0.030
Why?
Electron Transport Chain Complex Proteins
1
2016
20
0.030
Why?
Larva
1
2017
242
0.030
Why?
Microscopy, Electron, Transmission
2
2007
156
0.030
Why?
Ubiquitinated Proteins
1
2016
2
0.030
Why?
HEK293 Cells
1
2019
745
0.030
Why?
Analysis of Variance
2
2012
1302
0.030
Why?
Transcriptional Elongation Factors
1
2016
40
0.030
Why?
Unfolded Protein Response
1
2016
58
0.030
Why?
Electron Transport
1
2016
110
0.030
Why?
Nerve Degeneration
1
2016
49
0.030
Why?
Mass Spectrometry
2
2012
728
0.030
Why?
Heterogeneous-Nuclear Ribonucleoprotein Group F-H
1
2015
1
0.030
Why?
Ginkgo biloba
2
2006
10
0.030
Why?
Atrophy
1
2016
201
0.030
Why?
Drosophila Proteins
1
2017
215
0.030
Why?
Fluorescence
1
2015
161
0.030
Why?
p38 Mitogen-Activated Protein Kinases
1
2016
264
0.030
Why?
Spectrometry, Fluorescence
1
2015
166
0.030
Why?
Polyadenylation
1
2015
39
0.030
Why?
Sex Factors
1
2021
2136
0.030
Why?
Parkinson Disease
1
2001
613
0.030
Why?
Homeostasis
1
2019
651
0.030
Why?
Protein Conformation
1
2017
943
0.030
Why?
Genetic Association Studies
1
2015
374
0.020
Why?
Kidney
1
2021
1511
0.020
Why?
Clioquinol
1
2012
7
0.020
Why?
Propanols
1
2012
2
0.020
Why?
2,2'-Dipyridyl
1
2012
7
0.020
Why?
Hydrocarbons, Fluorinated
1
2012
8
0.020
Why?
Gene Expression Regulation, Developmental
1
2017
915
0.020
Why?
Fluoresceins
1
2012
48
0.020
Why?
Organ Culture Techniques
1
2012
154
0.020
Why?
Drug Evaluation, Preclinical
1
2012
196
0.020
Why?
Apoptosis
2
2012
2454
0.020
Why?
Cognition
1
2020
1286
0.020
Why?
Disulfides
1
2012
94
0.020
Why?
Models, Molecular
1
2016
1606
0.020
Why?
Gonads
1
2011
22
0.020
Why?
Membrane Potentials
1
2012
278
0.020
Why?
Nuclear Proteins
1
2016
745
0.020
Why?
Patch-Clamp Techniques
1
2012
289
0.020
Why?
Electric Stimulation
1
2012
277
0.020
Why?
Germ Cells
1
2011
66
0.020
Why?
Rats, Sprague-Dawley
2
2007
2542
0.020
Why?
Alanine
1
2012
173
0.020
Why?
Cysteine
1
2012
211
0.020
Why?
Microarray Analysis
1
2010
117
0.020
Why?
Aged, 80 and over
1
2003
8432
0.020
Why?
Quality of Life
1
2022
3246
0.020
Why?
Blood Pressure
2
2007
1785
0.020
Why?
Forkhead Transcription Factors
1
2010
210
0.020
Why?
Association Learning
1
2010
70
0.020
Why?
Central Nervous System Depressants
1
2010
84
0.020
Why?
Odorants
1
2010
114
0.020
Why?
Ribosomes
1
2010
193
0.020
Why?
Obesity
1
2022
3149
0.020
Why?
Ubiquitin
1
2009
84
0.020
Why?
Caenorhabditis
1
1988
4
0.020
Why?
Microscopy, Interference
1
1988
8
0.020
Why?
Sex Determination Analysis
1
1988
10
0.020
Why?
Caspases
1
2009
233
0.020
Why?
Serotonin
1
2010
300
0.020
Why?
Hot Temperature
1
2010
396
0.020
Why?
Receptors, Mineralocorticoid
1
2007
11
0.020
Why?
Paresis
1
2006
30
0.020
Why?
Malondialdehyde
1
2006
31
0.020
Why?
Valsartan
1
2006
33
0.010
Why?
Peptidyl-Dipeptidase A
1
2006
57
0.010
Why?
Angiotensin II Type 1 Receptor Blockers
1
2006
39
0.010
Why?
Chemotaxis
1
2006
122
0.010
Why?
Tetrazoles
1
2006
50
0.010
Why?
Neprilysin
1
2006
47
0.010
Why?
Valine
1
2006
83
0.010
Why?
Kidney Glomerulus
1
2006
125
0.010
Why?
Podocytes
1
2006
80
0.010
Why?
Dynamins
1
2005
37
0.010
Why?
Albuminuria
1
2006
189
0.010
Why?
Immunoprecipitation
1
2005
149
0.010
Why?
Motor Activity
1
2010
719
0.010
Why?
Ethanol
1
2010
634
0.010
Why?
Crystallins
1
2005
61
0.010
Why?
Fibrosis
1
2007
568
0.010
Why?
Age Factors
1
2012
3372
0.010
Why?
Naphthoquinones
1
2003
20
0.010
Why?
Ventricular Dysfunction, Left
1
2007
394
0.010
Why?
Protein O-Methyltransferase
1
2003
1
0.010
Why?
Drug Resistance
1
2003
145
0.010
Why?
RNA, Spliced Leader
1
2002
12
0.010
Why?
Trans-Splicing
1
2002
12
0.010
Why?
Myocytes, Cardiac
1
2007
548
0.010
Why?
Gene Silencing
1
2003
203
0.010
Why?
Myocardium
1
2007
949
0.010
Why?
Chronic Disease
1
2007
1845
0.010
Why?
Reactive Oxygen Species
1
2003
617
0.010
Why?
Pilot Projects
1
2005
1912
0.010
Why?
Magnetic Resonance Imaging
1
2007
3980
0.010
Why?
Adult
1
2015
41406
0.010
Why?
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