 Frailty
"Frailty" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A state of increased vulnerability to stressors, following declines in function and reserves across multiple physiologic systems, characterized by MUSCLE WEAKNESS; FATIGUE; slowed motor performance; low physical activity; and unintentional weight loss.
| Descriptor ID |
D000073496
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| MeSH Number(s) |
C23.550.359
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Frailty".
Below are MeSH descriptors whose meaning is more specific than "Frailty".
This graph shows the total number of publications written about "Frailty" by people in this website by year, and whether "Frailty" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 | | 2017 | 2 | 2 | 4 | | 2018 | 12 | 1 | 13 | | 2019 | 10 | 3 | 13 | | 2020 | 8 | 3 | 11 | | 2021 | 12 | 0 | 12 | | 2022 | 19 | 1 | 20 | | 2023 | 21 | 0 | 21 | | 2024 | 12 | 6 | 18 | | 2025 | 12 | 1 | 13 | | 2026 | 7 | 1 | 8 |
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Below are the most recent publications written about "Frailty" by people in Profiles.
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Freeman ML, Fitzgerald W, Clagett BM, O'Hare KA, Jonnalagadda V, Wilson BM, Margolis L, Wu K, Tassiopoulos K, Shive CL, Erlandson KM. Frailty in People with HIV Is Linked to Inflammation, Bone Health, and T-Cell Exhaustion. J Infect Dis. 2026 Jun 16; 233(6):995-1004.
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Bowman GI, Seymour N, Reynolds C, Evans LM. Development and validation of an electronic health record-based frailty index in the UK Biobank. J Gerontol A Biol Sci Med Sci. 2026 Jun 06; 81(7).
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Byun JY, Jones R, Iriarte E, Xavier Hall CD, Krause KD, Wang CX, Pahwa S, Lam JO, Falutz J, Masters MC, Corley M, Marzolini C, Greene M, Vera J, Siegler EL, Margolick JB, Ellis RJ, Letendre S, Moore DJ. Current perspectives and emerging directions in research and practice: highlights from the 15th Annual International Workshop on Aging and HIV. J Gerontol A Biol Sci Med Sci. 2026 May 07; 81(6).
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Abdo M, Kunisaki KM, Morris A, Stosor V, Chang D, D'Souza G, Crothers K, Abdel-Maksoud M, DiGuiseppi C, Brown TT, MaWhinney S, Erlandson KM. Frailty, Physical Function Impairment, and Pulmonary Function in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study. AIDS Res Hum Retroviruses. 2026 Jun-Jul; 42(6-7):222-226.
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Farid M, Wang J, Perdikis B, Blasdel N, Darko K, O'Leary S, Barrie U, Khan H, Aoun SG. Assessing the Assessors: Comparative performance of frailty and nutritional metrics in predicting 30-Day morbidity and mortality after cranial neurosurgery. J Clin Neurosci. 2026 Aug; 150:112047.
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Cabello Ubeda A, Erlandson KM, Freeman ML, Letendre SL, Wanjalla CN, Koethe JR, Corley MJ, Hunt PW, Gianella S. Cytomegalovirus in HIV: A Modifiable Driver of Inflammation, Frailty, and Aging. Curr HIV/AIDS Rep. 2026 Mar 20; 23(1).
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Araya AX, Iriarte E, Fernández-Lorca MB, Cornejo C. Sex Differences in Predictors of Frailty among Community-Dwelling Older Adults: Machine Learning Approach. Clin Nurs Res. 2026 Mar; 35(2-3):93-101.
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Smith KC, Brown C, Hyle EP, Zafarnejad R, Brown TT, Freedberg KA, Erlandson KM, Losina E. Modeled Health and Economic Burden of Frailty and Falls Among Adults With HIV. JAMA Netw Open. 2026 Jan 02; 9(1):e2554809.
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Kulik GL, Hsu HY, Rudolph J, Jiang Y, Erlandson KM, Piggott DA, Mehta S, Walston JD, Kirk G, Brown TT, Sun J. The association of methadone use with physical function and frailty among persons who inject drugs. Addiction. 2026 May; 121(5):1217-1226.
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Walker C, Nicholas J, Szczesny C, Walston J, Agrawal Y, Schubert MC. "Balance T" device improves balance confidence and performance in repeated measures study. J Frailty Aging. 2025 Dec; 14(6):100113.
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