Proteostasis
"Proteostasis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulation of the concentration, folding, interactions, and cellular localization of each of the proteins that comprise the PROTEOME.
Descriptor ID |
D000074702
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MeSH Number(s) |
G02.111.730 G03.816
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Concept/Terms |
Proteostasis- Proteostasis
- Proteostases
- Protein Homeostasis
- Homeostases, Protein
- Homeostasis, Protein
- Protein Homeostases
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Below are MeSH descriptors whose meaning is more general than "Proteostasis".
Below are MeSH descriptors whose meaning is more specific than "Proteostasis".
This graph shows the total number of publications written about "Proteostasis" by people in this website by year, and whether "Proteostasis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 0 | 1 | 2018 | 2 | 0 | 2 | 2019 | 2 | 0 | 2 | 2020 | 1 | 1 | 2 | 2022 | 2 | 0 | 2 | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proteostasis" by people in Profiles.
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Hernandez-Candia CN, Brady BR, Harrison E, Tucker CL. A platform to induce and mature biomolecular condensates using chemicals and light. Nat Chem Biol. 2024 Apr; 20(4):452-462.
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Musci RV, Andrie KM, Walsh MA, Valenti ZJ, Linden MA, Afzali MF, Bork S, Campbell M, Johnson T, Kail TE, Martinez R, Nguyen T, Sanford J, Wist S, Murrell MD, McCord JM, Hybertson BM, Zhang Q, Javors MA, Santangelo KS, Hamilton KL. Phytochemical compound PB125 attenuates skeletal muscle mitochondrial dysfunction and impaired proteostasis in a model of musculoskeletal decline. J Physiol. 2023 06; 601(11):2189-2216.
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van de Veerdonk FL, Renga G, Pariano M, Bellet MM, Servillo G, Fallarino F, De Luca A, Iannitti RG, Piobbico D, Gargaro M, Manni G, D'Onofrio F, Stincardini C, Sforna L, Borghi M, Castelli M, Pieroni S, Oikonomou V, Villella VR, Puccetti M, Giovagnoli S, Galarini R, Barola C, Maiuri L, Della Fazia MA, Cellini B, Talesa VN, Dinarello CA, Costantini C, Romani L. Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy. J Clin Invest. 2022 01 18; 132(2).
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Burchill MA, Finlon JM, Goldberg AR, Gillen AE, Dahms PA, McMahan RH, Tye A, Winter AB, Reisz JA, Bohrnsen E, Schafer JB, D'Alessandro A, Orlicky DJ, Kriss MS, Rosen HR, McCullough RL, Jir?n Tamburini BA. Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System. Cell Mol Gastroenterol Hepatol. 2021; 11(2):573-595.
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Moon SL, Morisaki T, Stasevich TJ, Parker R. Coupling of translation quality control and mRNA targeting to stress granules. J Cell Biol. 2020 08 03; 219(8).
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Moreno DF, Aldea M. Proteostatic stress as a nodal hallmark of replicative aging. Exp Cell Res. 2020 09 15; 394(2):112163.
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Moreno DF, Jenkins K, Morlot S, Charvin G, Csikasz-Nagy A, Aldea M. Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1. Elife. 2019 09 13; 8.
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Guerrero-G?mez D, Mora-Lorca JA, S?enz-Narciso B, Naranjo-Galindo FJ, Mu?oz-Lobato F, Parrado-Fern?ndez C, Goikolea J, Cedazo-Minguez ?, Link CD, Neri C, Sequedo MD, V?zquez-Manrique RP, Fern?ndez-Su?rez E, Goder V, Pan? R, Cabiscol E, Askjaer P, Cabello J, Miranda-Vizuete A. Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation. Cell Death Differ. 2019 09; 26(9):1545-1565.
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Kammerl IE, Caniard A, Merl-Pham J, Ben-Nissan G, Mayr CH, Mossina A, Geerlof A, Eickelberg O, Hauck SM, Sharon M, Meiners S. Dissecting the molecular effects of cigarette smoke on proteasome function. J Proteomics. 2019 02 20; 193:1-9.
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Reisz JA, Barrett AS, Nemkov T, Hansen KC, D'Alessandro A. When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies. Expert Rev Proteomics. 2018 04; 15(4):293-309.
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