 Molecular Chaperones
"Molecular Chaperones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.
| Descriptor ID |
D018832
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| MeSH Number(s) |
D12.776.580
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| Concept/Terms |
Molecular Chaperones- Molecular Chaperones
- Molecular Chaperone
- Chaperone, Molecular
- Chaperones, Molecular
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Below are MeSH descriptors whose meaning is more general than "Molecular Chaperones".
Below are MeSH descriptors whose meaning is more specific than "Molecular Chaperones".
This graph shows the total number of publications written about "Molecular Chaperones" by people in this website by year, and whether "Molecular Chaperones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 2 | 0 | 2 | | 2002 | 4 | 5 | 9 | | 2003 | 2 | 3 | 5 | | 2004 | 4 | 4 | 8 | | 2005 | 4 | 2 | 6 | | 2006 | 6 | 3 | 9 | | 2007 | 4 | 3 | 7 | | 2008 | 6 | 7 | 13 | | 2009 | 4 | 3 | 7 | | 2010 | 3 | 0 | 3 | | 2011 | 2 | 3 | 5 | | 2012 | 4 | 2 | 6 | | 2013 | 6 | 6 | 12 | | 2014 | 4 | 5 | 9 | | 2015 | 2 | 4 | 6 | | 2016 | 1 | 2 | 3 | | 2017 | 6 | 0 | 6 | | 2018 | 3 | 2 | 5 | | 2019 | 6 | 4 | 10 | | 2020 | 2 | 1 | 3 | | 2021 | 1 | 2 | 3 | | 2022 | 0 | 5 | 5 | | 2023 | 0 | 1 | 1 | | 2024 | 2 | 4 | 6 | | 2025 | 4 | 0 | 4 |
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Below are the most recent publications written about "Molecular Chaperones" by people in Profiles.
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Wu J, Wan C, Tian Y, Ouyang Y, Puscher H, Li S, Yin Q, Shen J. Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism. Sci Adv. 2025 Sep 12; 11(37):eadw9158.
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Conte AN, Ruchel ME, Ridgeway SM, Kibby EM, Nagy TA, Whiteley AT. DnaJ mediates phage sensing by the bacterial NLR-related protein bNACHT25. PLoS Biol. 2025 May; 23(5):e3003203.
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Das E, Le L, Sokolova V, Orth JD, Park S. Spatial mechanisms of quality control during chaperone-mediated assembly of the proteasome. Nat Commun. 2025 Apr 09; 16(1):3358.
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Flick H, Venbakkam A, Singh PK, Layish B, Huang S-W, Radhakrishnan R, Kvaratskhelia M, Engelman AN, Kane M. Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins. mBio. 2025 Mar 12; 16(3):e0264624.
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Parker DM, Tauber D, Parker R. G3BP1 promotes intermolecular RNA-RNA interactions during RNA condensation. Mol Cell. 2025 Feb 06; 85(3):571-584.e7.
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Roychowdhury T, McNutt SW, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, De Stanchina E, Corben A, Modi S, Alpaugh ML, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F. Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation. Nat Commun. 2024 10 16; 15(1):8912.
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Wan C, Puscher H, Ouyang Y, Wu J, Tian Y, Li S, Yin Q, Shen J. An AAGAB-to-CCDC32 handover mechanism controls the assembly of the AP2 adaptor complex. Proc Natl Acad Sci U S A. 2024 Aug 20; 121(34):e2409341121.
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Kilic-Berkmen G, Scorr LM, McKay L, Thayani M, Donsante Y, Perlmutter JS, Norris SA, Wright L, Klein C, Feuerstein JS, Mahajan A, Wagle-Shukla A, Malaty I, LeDoux MS, Pirio-Richardson S, Pantelyat A, Moukheiber E, Frank S, Ondo W, Saunders-Pullman R, Lohmann K, Hess EJ, Jinnah HA. Sex Differences in Dystonia. Mov Disord Clin Pract. 2024 08; 11(8):973-982.
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Doody A, Alfano L, Diaz-Manera J, Lowes L, Mozaffar T, Mathews KD, Weihl CC, Wicklund M, Hung M, Statland J, Johnson NE. Defining clinical endpoints in limb girdle muscular dystrophy: a GRASP-LGMD study. BMC Neurol. 2024 Mar 15; 24(1):96.
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Sánchez-Morán H, Kaar JL, Schwartz DK. Supra-biological performance of immobilized enzymes enabled by chaperone-like specific non-covalent interactions. Nat Commun. 2024 Mar 14; 15(1):2299.
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