 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1995 | 4 | 0 | 4 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 2 | 1 | 3 | | 2003 | 6 | 0 | 6 | | 2004 | 3 | 1 | 4 | | 2005 | 2 | 2 | 4 | | 2006 | 0 | 1 | 1 | | 2007 | 6 | 1 | 7 | | 2008 | 7 | 1 | 8 | | 2009 | 5 | 1 | 6 | | 2010 | 1 | 1 | 2 | | 2011 | 7 | 2 | 9 | | 2012 | 8 | 1 | 9 | | 2013 | 7 | 0 | 7 | | 2014 | 9 | 0 | 9 | | 2015 | 8 | 1 | 9 | | 2016 | 7 | 0 | 7 | | 2017 | 21 | 0 | 21 | | 2018 | 18 | 2 | 20 | | 2019 | 14 | 2 | 16 | | 2020 | 13 | 4 | 17 | | 2021 | 10 | 0 | 10 | | 2022 | 12 | 0 | 12 | | 2023 | 15 | 0 | 15 | | 2024 | 3 | 0 | 3 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Bock MA, Macchi ZA, Harrison KL, Katz M, Dini M, Jones J, Ayele R, Kutner JS, Pantilat SZ, Martin C, Sillau S, Kluger B. Does a novel community-based outpatient palliative care intervention for Parkinson's disease and related disorders improve care? Qualitative results from patients and care partners. Palliat Med. 2024 Feb; 38(2):240-250.
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Philippou E, Hirsch MA, Heyn PC, van Wegen EEH, Darwish H. Vitamin D and Brain Health in Alzheimer and Parkinson Disease. Arch Phys Med Rehabil. 2024 04; 105(4):809-812.
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Kluger BM, Katz M, Galifianakis NB, Pantilat SZ, Hauser JM, Khan R, Friedman C, Vaughan CL, Goto Y, Long SJ, Martin CS, Dini M, McQueen RB, Palmer L, Fairclough D, Seeberger LC, Sillau SH, Kutner JS. Patient and Family Outcomes of Community Neurologist Palliative Education and Telehealth Support in Parkinson Disease. JAMA Neurol. 2024 Jan 01; 81(1):39-49.
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Griffith G, Lamotte G, Mehta N, Fan P, Nikolich J, Springman V, Suttman E, Joslin E, Balfany K, Dunlap M, Kohrt WM, Christiansen CL, Melanson EL, Josbeno D, Chahine LM, Patterson CG, Corcos DM. Chronotropic Incompetence During Exercise Testing as a Marker of Autonomic Dysfunction in Individuals with Early Parkinson's Disease. J Parkinsons Dis. 2024; 14(1):121-133.
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Seshadri S, Dini M, Corcoran J, Job A, Contento A, Norton SA, Holtrop JS, Kluger BM. Parkinson disease patients' and carepartners' perceptions of palliative care. Parkinsonism Relat Disord. 2024 Feb; 119:105982.
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Feuerstein JS, Amara A. REM Behavior Disorder: Implications for PD Therapeutics. Curr Neurol Neurosci Rep. 2023 11; 23(11):727-734.
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Mahes A, Macchi ZA, Martin CS, Katz M, Galifianakis NB, Pantilat SZ, Kutner JS, Sillau S, Kluger BM. The "Surprise Question" for Prognostication in People With Parkinson's Disease and Related Disorders. J Pain Symptom Manage. 2024 01; 67(1):e1-e7.
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Barcomb K, Ford CP. Alterations in neurotransmitter co-release in Parkinson's disease. Exp Neurol. 2023 12; 370:114562.
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Zhao A, Cui E, Leroux A, Lindquist MA, Crainiceanu CM. Evaluating the prediction performance of objective physical activity measures for incident Parkinson's disease in the UK Biobank. J Neurol. 2023 Dec; 270(12):5913-5923.
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Amo-Aparicio J, Daly J, H?jen JF, Dinarello CA. Pharmacologic inhibition of NLRP3 reduces the levels of a-synuclein and protects dopaminergic neurons in a model of Parkinson's disease. J Neuroinflammation. 2023 Jun 22; 20(1):147.
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