 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 4 | 0 | 4 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 2 | 1 | 3 | | 2001 | 3 | 1 | 4 | | 2002 | 3 | 1 | 4 | | 2003 | 6 | 0 | 6 | | 2004 | 3 | 1 | 4 | | 2005 | 2 | 3 | 5 | | 2006 | 0 | 1 | 1 | | 2007 | 7 | 1 | 8 | | 2008 | 7 | 1 | 8 | | 2009 | 5 | 2 | 7 | | 2010 | 2 | 1 | 3 | | 2011 | 9 | 2 | 11 | | 2012 | 8 | 1 | 9 | | 2013 | 6 | 0 | 6 | | 2014 | 11 | 2 | 13 | | 2015 | 9 | 1 | 10 | | 2016 | 7 | 0 | 7 | | 2017 | 24 | 0 | 24 | | 2018 | 20 | 2 | 22 | | 2019 | 19 | 2 | 21 | | 2020 | 17 | 4 | 21 | | 2021 | 11 | 0 | 11 | | 2022 | 13 | 1 | 14 | | 2023 | 25 | 0 | 25 | | 2024 | 17 | 1 | 18 | | 2025 | 4 | 0 | 4 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Vaillancourt DE, Barmpoutis A, Wu SS, DeSimone JC, Schauder M, Chen R, Parrish TB, Wang WE, Molho E, Morgan JC, Simon DK, Scott BL, Rosenthal LS, Gomperts SN, Akhtar RS, Grimes D, De Jesus S, Stover N, Bayram E, Ramirez-Zamora A, Prokop S, Fang R, Slevin JT, Kanel P, Bohnen NI, Tuite P, Aradi S, Strafella AP, Siddiqui MS, Davis AA, Huang X, Ostrem JL, Fernandez H, Litvan I, Hauser RA, Pantelyat A, McFarland NR, Xie T, Okun MS, Leader A, Russell ?, Babcock H, White-Tong K, Hua J, Goodheart AE, Peterec EC, Poon C, Galarce MB, Thompson T, Collier AM, Cromer C, Putra N, Costello R, Yilmaz E, Mercado C, Mercado T, Fessenden A, Wagner R, Spears CC, Caswell JL, Bryants M, Kuzianik K, Ahmed Y, Bendahan N, Njoku JO, Stiebel A, Zahed H, Wang SS, Hoang PT, Seemiller J, Du G. Automated Imaging Differentiation for Parkinsonism. JAMA Neurol. 2025 May 01; 82(5):495-505.
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Platt JP, Radcliffe EM, Klimczak SL, Gliske SV, Kovach CK, Maroni D, Abosch A, Thompson JA. Multi-day recordings and adaptive stimulation protocols for in-home collection of deep brain stimulation intracranial recordings. J Neurosci Methods. 2025 Jun; 418:110442.
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Santangelo BE, Bada M, Hunter LE, Lozupone C. Hypothesizing mechanistic links between microbes and disease using knowledge graphs. Sci Rep. 2025 Feb 26; 15(1):6905.
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Griffith GJ, Mehta N, Lamotte G, McKee KE, Suttman E, Haus JM, Joslin E, Balfany K, Kohrt WM, Christiansen CL, Melanson EL, Chahine LM, Christou DD, Patterson CG, Corcos DM. Effects of 6 months of endurance exercise on motor function, exercise capacity, and autonomic function based on presence of autonomic dysfunction in individuals with early Parkinson's disease. J Parkinsons Dis. 2025 Mar; 15(2):387-396.
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Fullard ME, Dafoe A, Shelton E, Kern DS, Matlock DD, Morris MA. How Women and Men with Parkinson's Disease Approach Decision-Making for Deep Brain Stimulation Surgery. Mov Disord Clin Pract. 2025 Apr; 12(4):453-463.
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Das R, Gliske SV, Maroni D, Situ-Kcomt M, West LC, Summers MO, Tang S, Vaswani PA, Halpern CH, Thompson JA, Kushida CA, Abosch A. Sleep spindle variation in patients with Parkinson's disease on first nights of sub-optimal deep brain stimulation. Clin Neurophysiol. 2025 Feb; 170:91-97.
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Nielsen BE, Ford CP. Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA-induced dyskinetic behaviors. Sci Adv. 2024 Nov 22; 10(47):eadp6301.
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Petkus AJ, Donahue E, Jakowec MW, Bayram E, Van Horn JD, Litvan I, Petzinger GM, Schiehser DM. Data-driven sequence of cognitive decline in people with Parkinson's disease. J Neurol Neurosurg Psychiatry. 2024 Nov 18; 95(12):1123-1131.
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Das R, Gliske SV, West LC, Summers MO, Tang S, Hirt L, Maroni D, Halpern CH, Thompson JA, Kushida CA, Abosch A. Sleep macro-architecture in patients with Parkinson's disease does not change during the first night of neurostimulation in a pilot study. J Clin Sleep Med. 2024 Sep 01; 20(9):1489-1496.
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Amara AW, Catiul C, Videnovic A. Let there be light for Parkinson's disease... but only at the right time. Sleep. 2024 08 14; 47(8).
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