 Astrocytes
"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
| Descriptor ID |
D001253
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| MeSH Number(s) |
A08.637.200 A11.650.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 6 | 6 | | 2004 | 2 | 3 | 5 | | 2005 | 1 | 5 | 6 | | 2006 | 2 | 0 | 2 | | 2007 | 2 | 1 | 3 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 3 | 3 | | 2010 | 0 | 2 | 2 | | 2011 | 1 | 5 | 6 | | 2012 | 8 | 1 | 9 | | 2013 | 2 | 2 | 4 | | 2014 | 2 | 3 | 5 | | 2015 | 4 | 2 | 6 | | 2016 | 1 | 1 | 2 | | 2017 | 6 | 4 | 10 | | 2018 | 3 | 2 | 5 | | 2019 | 5 | 5 | 10 | | 2020 | 2 | 1 | 3 | | 2021 | 7 | 1 | 8 | | 2022 | 5 | 4 | 9 | | 2023 | 3 | 6 | 9 | | 2024 | 5 | 3 | 8 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Gupta M, Khandelwal NK, Nelson A, Hwang P, Pourmal S, Bennett JL, Stroud RM. Structural basis of aquaporin-4 autoantibody binding in neuromyelitis optica. Sci Adv. 2025 Feb 21; 11(8):eadq7560.
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Bosquez Huerta NA, Lee ZF, Christine Song EA, Woo J, Cheng YT, Sardar D, Sert O, Maleki E, Yu K, Akdemir ES, Sanchez K, Jo J, Rasband MN, Lee HK, Harmanci AS, Deneen B. Sex-specific astrocyte regulation of spinal motor circuits by Nkx6.1. Cell Rep. 2025 01 28; 44(1):115121.
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Williamson MR, Kwon W, Woo J, Ko Y, Maleki E, Yu K, Murali S, Sardar D, Deneen B. Learning-associated astrocyte ensembles regulate memory recall. Nature. 2025 Jan; 637(8045):478-486.
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Lemieux MR, Freigassner B, Hanson JL, Thathey Z, Opp MR, Hoeffer CA, Link CD. Multielectrode array characterization of human induced pluripotent stem cell derived neurons in co-culture with primary human astrocytes. PLoS One. 2024; 19(6):e0303901.
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Thomas CI, Ryan MA, McNabb MC, Kamasawa N, Scholl B. Astrocyte coverage of excitatory synapses correlates to measures of synapse structure and function in ferret primary visual cortex. Glia. 2024 Oct; 72(10):1785-1800.
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Zhang S, Heil BJ, Mao W, Chikina M, Greene CS, Heller EA. MousiPLIER: A Mouse Pathway-Level Information Extractor Model. eNeuro. 2024 Jun; 11(6).
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Granholm AE, Englund E, Gilmore A, Head E, Yong WH, Perez SE, Guzman SJ, Hamlett ED, Mufson EJ. Neuropathological findings in Down syndrome, Alzheimer's disease and control patients with and without SARS-COV-2: preliminary findings. Acta Neuropathol. 2024 05 27; 147(1):92.
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Brown JA, Faley SL, Judge M, Ward P, Ihrie RA, Carson R, Armstrong L, Sahin M, Wikswo JP, Ess KC, Neely MD. Rescue of impaired blood-brain barrier in tuberous sclerosis complex patient derived neurovascular unit. J Neurodev Disord. 2024 May 23; 16(1):27.
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Ye Q, Jo J, Wang CY, Oh H, Zhan J, Choy TJ, Kim KI, D'Alessandro A, Reshetnyak YK, Jung SY, Chen Z, Marrelli SP, Lee HK. Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation. Cell Rep. 2024 05 28; 43(5):114193.
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Lowe MC, Money KM, Matthews E, Pastula DM, Piquet AL. case of autoimmune GFAP astrocytopathy with eosinophils in the cerebrospinal fluid. J Neuroimmunol. 2023 12 15; 385:578249.
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