 Astrocytes
"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
| Descriptor ID |
D001253
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| MeSH Number(s) |
A08.637.200 A11.650.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 6 | 6 | | 2004 | 3 | 3 | 6 | | 2005 | 2 | 5 | 7 | | 2006 | 2 | 0 | 2 | | 2007 | 1 | 1 | 2 | | 2009 | 2 | 3 | 5 | | 2010 | 0 | 2 | 2 | | 2011 | 2 | 5 | 7 | | 2012 | 7 | 1 | 8 | | 2013 | 3 | 2 | 5 | | 2014 | 2 | 4 | 6 | | 2015 | 4 | 2 | 6 | | 2016 | 1 | 1 | 2 | | 2017 | 6 | 4 | 10 | | 2018 | 3 | 1 | 4 | | 2019 | 7 | 5 | 12 | | 2020 | 4 | 4 | 8 | | 2021 | 8 | 1 | 9 | | 2022 | 6 | 4 | 10 | | 2023 | 1 | 6 | 7 | | 2024 | 5 | 2 | 7 | | 2025 | 2 | 3 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Lee HY, Lee JM, Lee HL, Park J, An H, Park EK, Hwang SY, Yoon SL, Hwang GY, Kim KN, Nam MH, Lee SE, Kang H, Won J, Jang BK, Lee EH, Choi S, Park MG, Kim SW, Park KD, Lee S, Lee CJ, Ha Y. Astrocytic monoamine oxidase B (MAOB)-gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury. Signal Transduct Target Ther. 2025 Sep 11; 10(1):295.
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Lombardi AM, Griffioen M, Wong H, Milstead R, Borski C, Shiely E, Bower ME, Schmitt E, LaPlante L, Ehringer MA, Stitzel J, Hoeffer CA. AKT2 Modulates Astrocytic Nicotine Responses In Vivo. Glia. 2025 Oct; 73(10):2098-2129.
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Tegtmeyer M, Liyanage D, Han Y, Hebert KB, Pei R, Way GP, Ryder PV, Hawes D, Tromans-Coia C, Cimini BA, Carpenter AE, Singh S, Nehme R. Combining phenomics with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion. Nat Commun. 2025 Jul 09; 16(1):6332.
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Given KS, Acker EG, Macklin WB, Carlin D, Owens GP, Bennett JL. Complement inhibition rapidly blocks lesion extension and facilitates remyelination in neuromyelitis optica. Acta Neuropathol Commun. 2025 06 12; 13(1):129.
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Gupta M, Khandelwal NK, Nelson A, Hwang P, Pourmal S, Bennett JL, Stroud RM. Structural basis of aquaporin-4 autoantibody binding in neuromyelitis optica. Sci Adv. 2025 Feb 21; 11(8):eadq7560.
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Bosquez Huerta NA, Lee ZF, Christine Song EA, Woo J, Cheng YT, Sardar D, Sert O, Maleki E, Yu K, Akdemir ES, Sanchez K, Jo J, Rasband MN, Lee HK, Harmanci AS, Deneen B. Sex-specific astrocyte regulation of spinal motor circuits by Nkx6.1. Cell Rep. 2025 01 28; 44(1):115121.
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Williamson MR, Kwon W, Woo J, Ko Y, Maleki E, Yu K, Murali S, Sardar D, Deneen B. Learning-associated astrocyte ensembles regulate memory recall. Nature. 2025 Jan; 637(8045):478-486.
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Lemieux MR, Freigassner B, Hanson JL, Thathey Z, Opp MR, Hoeffer CA, Link CD. Multielectrode array characterization of human induced pluripotent stem cell derived neurons in co-culture with primary human astrocytes. PLoS One. 2024; 19(6):e0303901.
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Thomas CI, Ryan MA, McNabb MC, Kamasawa N, Scholl B. Astrocyte coverage of excitatory synapses correlates to measures of synapse structure and function in ferret primary visual cortex. Glia. 2024 Oct; 72(10):1785-1800.
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Zhang S, Heil BJ, Mao W, Chikina M, Greene CS, Heller EA. MousiPLIER: A Mouse Pathway-Level Information Extractor Model. eNeuro. 2024 Jun; 11(6).
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