 Virus Latency
"Virus Latency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.
| Descriptor ID |
D017735
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| MeSH Number(s) |
G06.920.900
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| Concept/Terms |
Virus Latency- Virus Latency
- Latencies, Virus
- Latency, Virus
- Virus Latencies
- Viral Latency
- Latencies, Viral
- Latency, Viral
- Viral Latencies
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Below are MeSH descriptors whose meaning is more general than "Virus Latency".
Below are MeSH descriptors whose meaning is more specific than "Virus Latency".
This graph shows the total number of publications written about "Virus Latency" by people in this website by year, and whether "Virus Latency" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 1 | 2 | | 2002 | 4 | 1 | 5 | | 2003 | 2 | 1 | 3 | | 2004 | 2 | 2 | 4 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2009 | 2 | 2 | 4 | | 2010 | 2 | 3 | 5 | | 2011 | 0 | 1 | 1 | | 2012 | 4 | 0 | 4 | | 2013 | 2 | 3 | 5 | | 2014 | 3 | 2 | 5 | | 2015 | 2 | 1 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 4 | 2 | 6 | | 2019 | 4 | 0 | 4 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 1 | 2 | | 2023 | 0 | 3 | 3 | | 2024 | 0 | 2 | 2 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Virus Latency" by people in Profiles.
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Collins-McMillen D, De Oliveira Pessoa D, Zarrella K, Parkins CJ, Daily M, McKinzey DR, Moorman NJ, Kamil JP, Caposio P, Padi M, Goodrum FD. Viral and host network analysis of the human cytomegalovirus transcriptome in latency. Proc Natl Acad Sci U S A. 2025 Jun 03; 122(22):e2416114122.
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Niemeyer CS, Merle L, Bubak AN, Baxter BD, Gentile Polese A, Colon-Reyes K, Vang S, Hassell JE, Bruce KD, Nagel MA, Restrepo D. Olfactory and trigeminal routes of HSV-1 CNS infection with regional microglial heterogeneity. J Virol. 2024 Nov 19; 98(11):e0096824.
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Hyder U, Shukla A, Challa A, D'Orso I. HIV-1 Proviral Genome Engineering with CRISPR-Cas9 for Mechanistic Studies. Viruses. 2024 02 13; 16(2).
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Sanz M, Weideman AMK, Ward AR, Clohosey ML, Garcia-Recio S, Selitsky SR, Mann BT, Iannone MA, Whitworth CP, Chitrakar A, Garrido C, Kirchherr J, Coffey AR, Tsai YH, Samir S, Xu Y, Copertino D, Bosque A, Jones BR, Parker JS, Hudgens MG, Goonetilleke N, Soriano-Sarabia N. Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1. Front Immunol. 2023; 14:1219250.
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Mlera L, Collins-McMillen D, Zeltzer S, Buehler JC, Moy M, Zarrella K, Caviness K, Cicchini L, Tafoya DJ, Goodrum F. Liver X Receptor-Inducible Host E3 Ligase IDOL Targets a Human Cytomegalovirus Reactivation Determinant. J Virol. 2023 07 27; 97(7):e0075823.
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Zarrella K, Longmire P, Zeltzer S, Collins-McMillen D, Hancock M, Buehler J, Reitsma JM, Terhune SS, Nelson JA, Goodrum F. Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection. PLoS Pathog. 2023 06; 19(6):e1011185.
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Niemeyer BF, Sanford B, Gibson JE, Berger JN, Oko LM, Medina E, Clambey ET, van Dyk LF. The gammaherpesvirus 68 viral cyclin facilitates expression of LANA. PLoS Pathog. 2021 11; 17(11):e1010019.
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Knox AN, Mueller A, Medina EM, Clambey ET, van Dyk LF. Lytic Infection with Murine Gammaherpesvirus 68 Activates Host and Viral RNA Polymerase III Promoters and Enhances Noncoding RNA Expression. J Virol. 2021 06 24; 95(14):e0007921.
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Taylor JP, Armitage LH, Aldridge DL, Cash MN, Wallet MA. Harmine enhances the activity of the HIV-1 latency-reversing agents ingenol A and SAHA. Biol Open. 2020 12 21; 9(12).
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Kennedy PG, Graner MW, Gunaydin D, Bowlin J, Pointon T, Yu X. Varicella-Zoster Virus infected human neurons are resistant to apoptosis. J Neurovirol. 2020 06; 26(3):330-337.
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