 Central Nervous System Depressants
"Central Nervous System Depressants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).
| Descriptor ID |
D002492
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| MeSH Number(s) |
D27.505.696.277 D27.505.954.427.210
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Central Nervous System Depressants".
Below are MeSH descriptors whose meaning is more specific than "Central Nervous System Depressants".
This graph shows the total number of publications written about "Central Nervous System Depressants" by people in this website by year, and whether "Central Nervous System Depressants" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 5 | 0 | 5 | | 2000 | 1 | 2 | 3 | | 2001 | 1 | 3 | 4 | | 2003 | 2 | 2 | 4 | | 2004 | 2 | 0 | 2 | | 2005 | 3 | 1 | 4 | | 2006 | 2 | 2 | 4 | | 2007 | 5 | 2 | 7 | | 2008 | 3 | 2 | 5 | | 2009 | 1 | 1 | 2 | | 2010 | 3 | 1 | 4 | | 2011 | 4 | 1 | 5 | | 2012 | 0 | 1 | 1 | | 2013 | 4 | 0 | 4 | | 2014 | 2 | 1 | 3 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 4 | 4 | | 2018 | 1 | 1 | 2 | | 2019 | 2 | 0 | 2 | | 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Central Nervous System Depressants" by people in Profiles.
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Steel TL, Afshar M, Edwards S, Jolley SE, Timko C, Clark BJ, Douglas IS, Dzierba AL, Gershengorn HB, Gilpin NW, Godwin DW, Hough CL, Maldonado JR, Mehta AB, Nelson LS, Patel MB, Rastegar DA, Stollings JL, Tabakoff B, Tate JA, Wong A, Burnham EL. Research Needs for Inpatient Management of Severe Alcohol Withdrawal Syndrome: An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2021 10 01; 204(7):e61-e87.
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Burnham NW, Chaimowitz CN, Vis CC, Segantine Dornellas AP, Navarro M, Thiele TE. Lateral hypothalamus-projecting noradrenergic locus coeruleus pathway modulates binge-like ethanol drinking in male and female TH-ires-cre mice. Neuropharmacology. 2021 09 15; 196:108702.
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Bauer EE, Shoeman A, Buhr TJ, Daniels KM, Lyte M, Clark PJ. Voluntary binge-patterned alcohol drinking and sex-specific influences on monoamine-related neurochemical signatures in the mouse gut and brain. Alcohol Clin Exp Res. 2021 05; 45(5):996-1012.
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Nief C, Morhard R, Chelales E, Adrianzen Alvarez D, Bourla Bs I, Lam CT, Sag AA, Crouch BT, Mueller JL, Katz D, Dewhirst MW, Everitt JI, Ramanujam N. Polymer-assisted intratumoral delivery of ethanol: Preclinical investigation of safety and efficacy in a murine breast cancer model. PLoS One. 2021; 16(1):e0234535.
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Tanabe J, Yamamoto DJ, Sutton B, Brown MS, Hoffman PL, Burnham EL, Glueck DH, Tabakoff B. Effects of Alcohol and Acetate on Cerebral Blood Flow: A Pilot Study. Alcohol Clin Exp Res. 2019 10; 43(10):2070-2078.
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Lindberg D, Ho AMC, Peyton L, Choi DS. Chronic Ethanol Exposure Disrupts Lactate and Glucose Homeostasis and Induces Dysfunction of the Astrocyte-Neuron Lactate Shuttle in the Brain. Alcohol Clin Exp Res. 2019 09; 43(9):1838-1847.
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Junker J, Brandt V, Berman BD, Vidailhet M, Roze E, Weissbach A, Comella C, Malaty IA, Jankovic J, LeDoux MS, Berardelli A, Barbano R, Reich SG, Perlmutter JS, Jinnah HA, Br?ggemann N. Predictors of alcohol responsiveness in dystonia. Neurology. 2018 11 20; 91(21):e2020-e2026.
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McCullough RL, McMullen MR, Sheehan MM, Poulsen KL, Roychowdhury S, Chiang DJ, Pritchard MT, Caballeria J, Nagy LE. Complement Factor D protects mice from ethanol-induced inflammation and liver injury. Am J Physiol Gastrointest Liver Physiol. 2018 07 01; 315(1):G66-G79.
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Ray LA, Green R, Roche DJO, Bujarski S, Hartwell EE, Lim AC, Rohrbaugh T, Ghahremani D, Hutchison K, Miotto K. Pharmacogenetic Effects of Naltrexone in Individuals of East Asian Descent: Human Laboratory Findings from a Randomized Trial. Alcohol Clin Exp Res. 2018 Mar; 42(3):613-623.
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Schacht JP, Voronin KE, Randall PK, Anton RF. Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial. Neuropsychopharmacology. 2018 05; 43(6):1247-1256.
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