 Protein Aggregates
"Protein Aggregates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any mixture of secondary, tertiary, or quaternary protein molecules which appear as clumps in or outside the cell.
| Descriptor ID |
D066329
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| MeSH Number(s) |
D05.875
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Aggregates".
Below are MeSH descriptors whose meaning is more specific than "Protein Aggregates".
This graph shows the total number of publications written about "Protein Aggregates" by people in this website by year, and whether "Protein Aggregates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 2 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 4 | 3 | 7 | | 2015 | 2 | 2 | 4 | | 2016 | 3 | 4 | 7 | | 2017 | 3 | 3 | 6 | | 2018 | 3 | 4 | 7 | | 2019 | 2 | 3 | 5 | | 2020 | 2 | 2 | 4 | | 2021 | 1 | 3 | 4 | | 2022 | 0 | 3 | 3 | | 2023 | 0 | 1 | 1 | | 2025 | 3 | 0 | 3 |
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Below are the most recent publications written about "Protein Aggregates" by people in Profiles.
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Pratt J, McCann K, Kuo J, Parker R. Polyserine-tau interactions modulate tau fibrillization. J Biol Chem. 2025 Sep; 301(9):110523.
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Upadhyay V, Panja S, Krishnamachari Y, Mittal SN, Xi H, Xu W, Song J, Hu G, Su Y, Mallela KMG. Effect of silicone oil on the structure, stability, and aggregation of a therapeutic antibody. J Pharm Sci. 2025 Aug; 114(8):103848.
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Van Alstyne M, Pratt J, Parker R. Diverse influences on tau aggregation and implications for disease progression. Genes Dev. 2025 May 02; 39(9-10):555-581.
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Lee LA, Barrick SK, Buvoli AE, Walklate J, Stump WT, Geeves M, Greenberg MJ, Leinwand LA. Distinct effects of two hearing loss-associated mutations in?the sarcomeric myosin MYH7b. J Biol Chem. 2023 05; 299(5):104631.
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Upadhyay AK, Mueller NH, Petrash JM, Kompella UB. Nano-assemblies enhance chaperone activity, stability, and delivery of alpha B-crystallin-D3 (aB-D3). J Control Release. 2022 12; 352:411-421.
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Thackray AM, Lam B, McNulty EE, Nalls AV, Mathiason CK, Magadi SS, Jackson WS, Andr?oletti O, Marrero-Winkens C, Sch?tzl H, Bujdoso R. Clearance of variant Creutzfeldt-Jakob disease prions in vivo by the Hsp70 disaggregase system. Brain. 2022 09 14; 145(9):3236-3249.
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Zoeller MP, Hafiz S, Marx A, Erwin N, Fricker G, Carpenter JF. Exploring the Protein Stabilizing Capability of Surfactants Against Agitation Stress and the Underlying Mechanisms. J Pharm Sci. 2022 12; 111(12):3261-3274.
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Calderon CP, Ripple DC, Srinivasan C, Ma Y, Carrier MJ, Randolph TW, O'Connor TF. Testing Precision Limits of Neural Network-Based Quality Control Metrics in High-Throughput Digital Microscopy. Pharm Res. 2022 Feb; 39(2):263-279.
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Ripin N, Parker R. Are stress granules the RNA analogs of misfolded protein aggregates? RNA. 2022 01; 28(1):67-75.
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Parashar S, Chidambaram R, Chen S, Liem CR, Griffis E, Lambert GG, Shaner NC, Wortham M, Hay JC, Ferro-Novick S. Endoplasmic reticulum tubules limit the size of misfolded protein condensates. Elife. 2021 09 01; 10.
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