 Insulin
"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
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| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 7 | 5 | 12 | | 1996 | 8 | 6 | 14 | | 1997 | 7 | 6 | 13 | | 1998 | 8 | 8 | 16 | | 1999 | 10 | 11 | 21 | | 2000 | 9 | 9 | 18 | | 2001 | 12 | 9 | 21 | | 2002 | 13 | 6 | 19 | | 2003 | 17 | 13 | 30 | | 2004 | 24 | 23 | 47 | | 2005 | 14 | 17 | 31 | | 2006 | 13 | 23 | 36 | | 2007 | 20 | 31 | 51 | | 2008 | 19 | 21 | 40 | | 2009 | 21 | 40 | 61 | | 2010 | 27 | 14 | 41 | | 2011 | 20 | 27 | 47 | | 2012 | 24 | 32 | 56 | | 2013 | 20 | 27 | 47 | | 2014 | 19 | 37 | 56 | | 2015 | 23 | 27 | 50 | | 2016 | 28 | 28 | 56 | | 2017 | 26 | 35 | 61 | | 2018 | 32 | 35 | 67 | | 2019 | 39 | 35 | 74 | | 2020 | 31 | 37 | 68 | | 2021 | 21 | 44 | 65 | | 2022 | 10 | 74 | 84 | | 2023 | 7 | 48 | 55 | | 2024 | 41 | 28 | 69 | | 2025 | 28 | 13 | 41 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Delong T, Nakayama M. Epitope Hierarchy in Type 1 Diabetes Pathogenesis. Cold Spring Harb Perspect Med. 2025 Nov 03; 15(11).
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Turner LV, Sherr JL, Zaharieva DP, Baran J, Hirsch IB, Bode BW, Brown SA, Bzdick S, Church MM, Hansen DW, Kingman R, Laffel LM, Shah VN, Stone S, Vienneau TE, Huyett LM, Dumais B, Ly TT, Riddell MC. Use of the Omnipod 5 Automated Insulin Delivery System Activity Feature Reduces Insulin Delivery and Attenuates the Drop in Glycemia Associated With Exercise in a Randomized Controlled Trial. Diabetes Care. 2025 Sep 01; 48(9):1598-1606.
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Michelsen TM, Sajjad MU, Haugen G, Moore L, Julian CG, Sørbye IK, Henriksen T. Maternal body mass index is related to fetal uptake of glucose and oxygen via fetal insulin resistance rather than fetal glucose levels. Philos Trans R Soc Lond B Biol Sci. 2025 Aug 21; 380(1933):20240178.
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Chan CL, Shirley Bezerra M, Stefanovski D, Gallop RJ, Walega R, Donaldson SH, Frederick CA, Freedman SD, Gelfond D, Hoffman LR, Narkewicz MR, Rowe SM, Sagel SD, Schwarzenberg SJ, Solomon GM, Stalvey MS, Kelly A. Glycemia and Insulin Secretion in Cystic Fibrosis 2 Years After Elexacaftor/Tezacaftor/Ivacaftor: PROMISE-ENDO. J Clin Endocrinol Metab. 2025 Aug 07; 110(9):2674-2684.
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Harrall KK, Glueck DH, Lange LA, Litkowski EM, Vanderlinden LA, Konigsberg IR, Cree MG, Perng W, Dabelea D. GLP-1R Gene Polymorphisms and Metabolic Traits During Childhood and Adolescence: The EPOCH Study. J Clin Endocrinol Metab. 2025 Aug 07; 110(9):e3031-e3040.
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Michels AW, Brusko TM, Evans-Molina C, Homann D, Richardson SJ, Powers AC. Challenges and Opportunities for Understanding the Pathogenesis of Type 1 Diabetes: An Endocrine Society Scientific Statement. J Clin Endocrinol Metab. 2025 Aug 07; 110(9):2496-2508.
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Presley CA, Butera NM, Krause-Steinrauf H, Desouza CV, Hollander PA, Hoogendoorn CJ, Lagari VS, Legowski EA, Martin CL, Rasouli N, Gonzalez JS, Cherrington AL. Lack of Association of Emotional Distress With Insulin Initiation in the GRADE Randomized Diabetes Comparative Effectiveness Trial. Sci Diabetes Self Manag Care. 2025 Aug; 51(4):382-393.
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Katte JC, Squires S, Dehayem MY, Balungi PA, Padoa CJ, Sengupta D, Fatumo S, Piloya T, Nyangabyaki-Twesigye C, Bahendeka S, Majaliwa E, Muze KC, Ramaiya K, Sap S, Motala AA, Pirie FJ, Rheeder P, Van Dyk JC, Mbanya JC, Shields BM, Shah AS, Pihoker C, Divers J, Patel KA, Oram RA, Dabelea D, Hattersley AT, McDonald TJ, Crowther NJ, Nyirenda MJ, Sobngwi E, Jones AG. Non-autoimmune, insulin-deficient diabetes in children and young adults in Africa: evidence from the Young-Onset Diabetes in sub-Saharan Africa (YODA) cross-sectional study. Lancet Diabetes Endocrinol. 2025 Sep; 13(9):745-753.
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Messer LH, Forlenza GP, Gonder-Frederick L, Hood K, Ebekozien O, Barnard-Kelly K, Laffel LM, Sherr JL, Lal R, Weinzimer SA. Practical Considerations and Implementation of Automated Insulin Delivery Systems. J Diabetes Sci Technol. 2025 Jul; 19(4):950-957.
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Bergenstal RM, Heller A, Breton MD, Vigersky R, Brown SA, Forlenza GP, Sherr JL, Hovorka R, Russell SJ, Damiano ER, Putman MS, Beck RW, Renard E, Lal R, Cobelli C, Dassau E, Akturk HK, Weiss MA, Skyler JS. Evolution of the Artificial Pancreas: Components and Integration-CGMs, Insulin, and AP Systems. J Diabetes Sci Technol. 2025 Jul; 19(4):883-894.
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