 Insulin
"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
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| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
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| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
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Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 6 | 5 | 11 | | 1996 | 8 | 6 | 14 | | 1997 | 7 | 6 | 13 | | 1998 | 8 | 8 | 16 | | 1999 | 10 | 11 | 21 | | 2000 | 9 | 9 | 18 | | 2001 | 12 | 10 | 22 | | 2002 | 13 | 6 | 19 | | 2003 | 17 | 13 | 30 | | 2004 | 24 | 22 | 46 | | 2005 | 14 | 17 | 31 | | 2006 | 13 | 21 | 34 | | 2007 | 18 | 30 | 48 | | 2008 | 19 | 20 | 39 | | 2009 | 20 | 39 | 59 | | 2010 | 27 | 14 | 41 | | 2011 | 20 | 27 | 47 | | 2012 | 24 | 33 | 57 | | 2013 | 18 | 26 | 44 | | 2014 | 17 | 36 | 53 | | 2015 | 23 | 26 | 49 | | 2016 | 24 | 27 | 51 | | 2017 | 23 | 34 | 57 | | 2018 | 29 | 35 | 64 | | 2019 | 35 | 35 | 70 | | 2020 | 28 | 37 | 65 | | 2021 | 19 | 44 | 63 | | 2022 | 10 | 72 | 82 | | 2023 | 6 | 48 | 54 | | 2024 | 38 | 26 | 64 | | 2025 | 10 | 7 | 17 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Hohenstein AC, Gallegos JB, Dang M, Groegler J, Broncucia H, Tensun FA, Waugh K, Dong F, James EA, Speake C, Steck AK, Rewers MJ, Gottlieb PA, Haskins K, Delong T, Baker RL. Novel T-Cell Reactivities to Hybrid Insulin Peptides in Islet Autoantibody-Positive At-Risk Individuals. Diabetes. 2025 Jun 01; 74(6):933-942.
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Mitro SD, Waetjen LE, Lee C, Wise LA, Zaritsky E, Harlow SD, El Khoudary SR, Santoro N, Solomon DH, Thurston RC, Hedderson MM. Diabetes and Uterine Fibroid Diagnosis in Midlife: Study of Women's Health Across the Nation (SWAN). J Clin Endocrinol Metab. 2025 May 19; 110(6):e1934-e1942.
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Berget C, Annan SF, Biester T, Choudhary P, Forlenza GP, Peters AL, Renard E, Deiss D. Practical considerations for using the Omnipod? 5 Automated Insulin Delivery System: Clinical experience from the United States and Europe. Diabetes Obes Metab. 2025 Jun; 27(6):2909-2919.
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Dovc K, Neuman V, Gita G, Cherubini V, Alonso GT, Fritsch M, Boettcher C, de Beaufort C, Holl RW, de Bock M. Association of Diabetic Ketoacidosis at Onset, Diabetes Technology Uptake, and Clinical Outcomes After 1 and 2 Years of Follow-up: A Collaborative Analysis of Pediatric Registries Involving 9,269 Children With Type 1 Diabetes From Nine Countries. Diabetes Care. 2025 Apr 01; 48(4):648-654.
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Sevilla-Gonz?lez M, Smith K, Wang N, Jensen AE, Litkowski EM, Kim H, DiCorpo DA, Hsu S, Cui J, Liu CT, Yu C, McNeil JJ, Lacaze P, Westerman KE, Chang KM, Tsao PS, Phillips LS, Goodarzi MO, Sladek R, Rotter JI, Dupuis J, Florez JC, Merino J, Meigs JB, Zhou JJ, Raghavan S, Udler MS, Manning AK. Heterogeneous effects of genetic variants and traits associated with fasting insulin on cardiometabolic outcomes. Nat Commun. 2025 Mar 15; 16(1):2569.
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King J, Buschur E, Garcetti R, Pyle L, Sakamoto C, Snell-Bergeon J, Nease E, Bartholomew A, Dungan K, Polsky S. Changes to insulin pump settings throughout pregnancy for individuals using assisted hybrid closed-loop therapy versus sensor-augmented pump therapy. J Diabetes Complications. 2025 Apr; 39(4):109000.
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Hirsch IB, Beck RW, Marak MC, Kudva Y, Akturk HK, Bhargava A, Codorniz K, Diner J, Aleppo G, Blevins T, Levy CJ, Raskin P, Castorino K, Manessis A, Pickering D, Steenkamp DW, Weinstock RS, Bode BW, Hamdy O, Nguyen QT, Kipnes M, Ruedy KJ, Desjardins D, Haider Z, Jacobson C, Lee S, Buse JB, Klein KR, O'Malley G, Church MM, Mottalib A, Baran JD, Kurek C, Rizvi S, Donahue C, Tamarez D, Atakov Castillo A, Borgman S, Frey S, Calhoun P. A Randomized Trial Comparing Inhaled Insulin Plus Basal Insulin Versus Usual Care in Adults With Type 1 Diabetes. Diabetes Care. 2025 Mar 01; 48(3):353-360.
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T Onetto M, Montt-Blanchard D, Berget C, Strodhoff K, Grassi B. Use of an Advanced Hybrid Closed Loop System During Marathon Running: Case Examples and Clinical Implications. Diabetes Metab Res Rev. 2025 Mar; 41(3):e70034.
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Beck RW, Bailey RJ, Akturk HK, Rizvi S, Kudva Y, Blevins T, Church MM, Manessis A, Calhoun P, Ruedy KJ, Hirsch IB. A 13-Week Single-Arm Evaluation of Inhaled Technosphere Insulin Plus Insulin Degludec for Adults with Type 1 Diabetes. Diabetes Technol Ther. 2025 Mar; 27(3):161-169.
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Zhao J, Massoudian SD, Stray-Gundersen S, Wojan F, Lalande S. Short bouts of hypoxia improve insulin sensitivity in adults with type 2 diabetes. J Appl Physiol (1985). 2025 Apr 01; 138(4):873-880.
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