Insulin
"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Descriptor ID |
D007328
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MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
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Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
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Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 6 | 5 | 11 | 1996 | 7 | 5 | 12 | 1997 | 7 | 6 | 13 | 1998 | 8 | 8 | 16 | 1999 | 10 | 11 | 21 | 2000 | 9 | 9 | 18 | 2001 | 8 | 4 | 12 | 2002 | 8 | 4 | 12 | 2003 | 16 | 13 | 29 | 2004 | 24 | 21 | 45 | 2005 | 14 | 16 | 30 | 2006 | 13 | 20 | 33 | 2007 | 17 | 28 | 45 | 2008 | 19 | 20 | 39 | 2009 | 18 | 37 | 55 | 2010 | 26 | 14 | 40 | 2011 | 19 | 26 | 45 | 2012 | 23 | 33 | 56 | 2013 | 17 | 24 | 41 | 2014 | 16 | 35 | 51 | 2015 | 23 | 26 | 49 | 2016 | 23 | 25 | 48 | 2017 | 23 | 32 | 55 | 2018 | 28 | 35 | 63 | 2019 | 35 | 35 | 70 | 2020 | 28 | 34 | 62 | 2021 | 19 | 41 | 60 | 2022 | 9 | 68 | 77 | 2023 | 5 | 47 | 52 | 2024 | 7 | 11 | 18 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Jones AG, Shields BM, Oram RA, Dabelea DM, Hagopian WA, Sharp SA, Lustigova E, Shah AS, Knupp J, Mottl AK, D'Agostino RB, Williams A, Marcovina SM, Pihoker C, Divers J, Redondo MJ. Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2024 Dec 01; 47(12):2110-2119.
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Akturk HK, Bindal A. Advances in diabetes technology within the digital diabetes ecosystem. J Manag Care Spec Pharm. 2024 Oct; 30(10-b Suppl):S7-S20.
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Hirsch IB, Beck RW, Marak MC, Calhoun P, Mottalib A, Salhin A, Manessis A, Coviello AD, Bhargava A, Thorsell A, Atakov Castillo A, Bode BW, Levister C, Levy CJ, Donahue C, Cordero C, Beatson C, Langel CR, Jacobson C, Kurek C, Cruse D, Pickering D, Tamarez D, Steenkamp DW, Desjardins D, Aleppo G, O'Malley G, Akturk HK, Diner J, Baran JD, Buse JB, Ruedy K, Codorniz K, Klein KR, Castorino K, Jordan LF, Kipnes M, Church MM, Hamdy O, Raskin P, Nguyen QT, Weinstock RS, Lee S, Rizvi S, Bzdick S, Ghorbani Rodriguez T, Salah T, Blevins T, Kudva YC, Haider Z. A Randomized Comparison of Postprandial Glucose Excursion Using Inhaled Insulin Versus Rapid-Acting Analog Insulin in Adults With Type 1 Diabetes Using Multiple Daily Injections of Insulin or Automated Insulin Delivery. Diabetes Care. 2024 Sep 01; 47(9):1682-1687.
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Haemmerle MW, Scota AV, Khosravifar M, Varney MJ, Sen S, Good AL, Yang X, Wells KL, Sussel L, Rozo AV, Doliba NM, Ghanem LR, Stoffers DA. RNA-binding protein PCBP2 regulates pancreatic ? cell function and adaptation to glucose. J Clin Invest. 2024 Jun 17; 134(12).
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Shapiro ALB, Tjaden AH, Edelstein SL, Kahn SE, Srikanthan P, Knowler WC, Venditti EM, Golden SH, Carmichael O, Luchsinger JA. The association of insulin responses and insulin sensitivity with cognition in adults with pre-diabetes: The Diabetes Prevention Program Outcomes Study. J Diabetes Complications. 2024 06; 38(6):108764.
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Hollander PA, Krause-Steinrauf H, Butera NM, Kazemi EJ, Ahmann AJ, Fattaleh BN, Johnson ML, Killean T, Lagari VS, Larkin ME, Legowski EA, Rasouli N, Willis HJ, Martin CL. The Use of Rescue Insulin in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness?Study?(GRADE). Diabetes Care. 2024 Apr 01; 47(4):638-645.
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Trojanowski PJ, Pardon A, Reynolds C, O'Donnell HK, Alonso GT, Majidi S, Snell-Bergeon J, Wadwa RP, Driscoll KA. Body mass index moderates the association between diabetes distress and objective self-management behaviours in adolescents with type 1 diabetes and elevated A1Cs. Diabet Med. 2024 Jul; 41(7):e15325.
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Tian T, Aaron RE, DuNova AY, Jendle JH, Kerr D, Cengiz E, Drincic A, Pickup JC, Chen KY, Schwartz N, Muchmore DB, Akturk HK, Levy CJ, Schmidt S, Bellazzi R, Wu AHB, Spanakis EK, Najafi B, Chase JG, Seley JJ, Klonoff DC. Diabetes Technology Meeting 2023. J Diabetes Sci Technol. 2024 Sep; 18(5):1208-1244.
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Carlson AL, Graham TE, Akturk HK, Liljenquist DR, Bergenstal RM, Sulik B, Shah VN, Sulik M, Zhao P, Briggs P, Sassan-Katchalski R, Pinsker JE. Control-IQ Technology Use in Individuals With High Insulin Requirements: Results From the Multicenter Higher-IQ Trial. J Diabetes Sci Technol. 2024 Nov; 18(6):1288-1292.
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Fordham TM, Morelli NS, Garcia-Reyes Y, Ware MA, Rahat H, Sundararajan D, Fuller KNZ, Severn C, Pyle L, Malloy CR, Jin ES, Parks EJ, Wolfe RR, Cree MG. Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity. Obesity (Silver Spring). 2024 04; 32(4):678-690.
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