Insulin
"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
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| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
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| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
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Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 8 | 6 | 14 | | 1997 | 7 | 6 | 13 | | 1998 | 8 | 8 | 16 | | 1999 | 10 | 11 | 21 | | 2000 | 9 | 9 | 18 | | 2001 | 11 | 9 | 20 | | 2002 | 12 | 6 | 18 | | 2003 | 16 | 13 | 29 | | 2004 | 24 | 22 | 46 | | 2005 | 14 | 16 | 30 | | 2006 | 13 | 23 | 36 | | 2007 | 17 | 30 | 47 | | 2008 | 19 | 21 | 40 | | 2009 | 22 | 40 | 62 | | 2010 | 28 | 15 | 43 | | 2011 | 21 | 27 | 48 | | 2012 | 25 | 34 | 59 | | 2013 | 21 | 27 | 48 | | 2014 | 17 | 39 | 56 | | 2015 | 25 | 29 | 54 | | 2016 | 30 | 30 | 60 | | 2017 | 24 | 34 | 58 | | 2018 | 30 | 35 | 65 | | 2019 | 37 | 36 | 73 | | 2020 | 30 | 36 | 66 | | 2021 | 21 | 46 | 67 | | 2022 | 10 | 74 | 84 | | 2023 | 7 | 51 | 58 | | 2024 | 44 | 28 | 72 | | 2025 | 43 | 17 | 60 | | 2026 | 14 | 12 | 26 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Hitt TA, Kelly A, Stefanovski D, Zemel BS, McCarter R, Yanek L, Zandieh G, Özdemir I, Kamel IR, Hui SCN, Barker P, Magge SN. Insulin Hypersecretion and Increased Ectopic Fat in South Asian American Adolescents and Young Adults Compared With White and African American Peers: The CHARISMA Study. Diabetes Care. 2026 Jun 01; 49(6):1057-1066.
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Ciccaglione M, Abenojar E, Kosmides T, DiLisio JE, McDaniel KA, Hartmoore K, Gresch A, Jarrell DK, Ramirez DG, Sticco-Ivins M, Michels AW, Haskins K, Exner AA, Benninger RKP. Submicron-sized ultrasound contrast agents as therapeutic peptide delivery vehicles in type 1 diabetes. Theranostics. 2026; 16(12):6692-6712.
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Bluestone JA, Herold KC, Sussel L. Type 1 Diabetes: Advances in Understanding and Treatment 100 Years after the Discovery of Insulin. Cold Spring Harb Perspect Med. 2026 May 01; 16(5).
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Karakus KE, Akturk HK, Kruger D, Ahmann A, Bharvaga A, Langel CR, Ackeifi CA, Rosen J, Pyle L, Snell-Bergeon JK, Shah VN. Effect of Semaglutide on Insulin Dose Reduction in Adults With Type 1 Diabetes and Obesity Using Automated Insulin Delivery Systems: ADJUST-T1D Post Hoc Analysis. Diabetes Care. 2026 May 01; 49(5):718-723.
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Beals JW, Smith GI, Farabi SS, Patterson BW, Lucey BP, Broussard JL, Wright KP, Klein S. Sleep Extension Improves Sleep Health but Not Insulin Sensitivity in People With Overweight or Obesity Who Maintain Habitual Short Sleep Schedules. Diabetes Care. 2026 May 01; 49(5):740-745.
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Seget S, Rusak E, Pelicand J, Fry M, Sheanon N, Schierloh U, Xatzipsalti M, Malinici E, Tinti D, Neylon O, Bazdarska Y, Cobry E, Hauser E. Automated insulin delivery use in children and adolescents with type 1 diabetes across the world. Diabetes Res Clin Pract. 2026 Jun; 236:113253.
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Juber MC, King-McAlpin S, Buscaglia P, Sebag JA, Potthoff MJ. FGF21 targets pathways which enhance insulin sensitivity in brown adipose but not skeletal muscle in mice. Endocrinology. 2026 Apr 07; 167(5).
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Levitt CH, Isaacs D, Hansen MS, Kravets V, Briggs JK, Benninger RKP. Diminished gap junction coupling under diabetogenic conditions does not drive loss of functional ß-cell subpopulations. J Gen Physiol. 2026 05 04; 158(3).
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DiLisio JE, Beard KS, Neef T, Miller SD, Wenzlau JM, Nakayama M, D'Antonio MA, Jamison BL, Nicholson KS, Baker RL, Brunetti TM, Gapin L, Haskins K. Antigen-specific immunotherapy with a CD4+ T cell neoepitope restrains CD8+ T cell differentiation in murine pancreatic islet grafts. Nat Commun. 2026 Mar 24; 17(1).
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Varela M, Chrisenberry DB, Johnson EH, Luna-Ramirez RI, Tracy AR, Kathuria S, Zhao W, Anderson MJ, Brown LD, Limesand SW. Oxygen and glucose supplementation increases rates of linear growth and cell proliferation in growth-restricted fetal sheep. J Physiol. 2026 04; 604(7):2778-2795.
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