Insulin
"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Descriptor ID |
D007328
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MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
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Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
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Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 7 | 5 | 12 | 1995 | 8 | 5 | 13 | 1996 | 7 | 4 | 11 | 1997 | 7 | 6 | 13 | 1998 | 9 | 7 | 16 | 1999 | 10 | 13 | 23 | 2000 | 9 | 9 | 18 | 2001 | 8 | 4 | 12 | 2002 | 7 | 5 | 12 | 2003 | 16 | 14 | 30 | 2004 | 24 | 21 | 45 | 2005 | 14 | 17 | 31 | 2006 | 14 | 21 | 35 | 2007 | 18 | 31 | 49 | 2008 | 18 | 20 | 38 | 2009 | 18 | 39 | 57 | 2010 | 28 | 14 | 42 | 2011 | 20 | 26 | 46 | 2012 | 23 | 33 | 56 | 2013 | 17 | 25 | 42 | 2014 | 17 | 38 | 55 | 2015 | 23 | 29 | 52 | 2016 | 23 | 27 | 50 | 2017 | 23 | 33 | 56 | 2018 | 28 | 36 | 64 | 2019 | 35 | 36 | 71 | 2020 | 28 | 35 | 63 | 2021 | 19 | 43 | 62 | 2022 | 7 | 68 | 75 | 2023 | 5 | 46 | 51 | 2024 | 0 | 5 | 5 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Hollander PA, Krause-Steinrauf H, Butera NM, Kazemi EJ, Ahmann AJ, Fattaleh BN, Johnson ML, Killean T, Lagari VS, Larkin ME, Legowski EA, Rasouli N, Willis HJ, Martin CL. The Use of Rescue Insulin in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness?Study?(GRADE). Diabetes Care. 2024 Apr 01; 47(4):638-645.
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Bjornstad P, Choi YJ, Platnick C, Gross S, Narongkiatikhun P, Melena I, Remmers L, Baca M, Schutte G, Dobbs T, Vigers T, Pyle L, Driscoll L, Tommerdahl K, Kendrick J, Looker HC, Dart A, Cherney D, van Raalte DH, Srivastava A, Li L, Prasad P, Saulnier P, Nelson RG, Johnson RJ, Nadeau KJ. Insulin Secretion, Sensitivity, and Kidney Function in Young Individuals With Type 2 Diabetes. Diabetes Care. 2024 Mar 01; 47(3):409-417.
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Visaria A, Huang SP, Su CC, Robinson D, Read J, Lin CY, Nethery R, Josey K, Gandhi P, Bates B, Rua M, Parthasarathi A, Ghosh AK, Kao Yang YH, Setoguchi S. Ambient Heat and Risk of Serious Hypoglycemia in Older Adults With Diabetes Using Insulin in the U.S. and Taiwan: A Cross-National Case-Crossover Study. Diabetes Care. 2024 Feb 01; 47(2):233-238.
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Hood KK, Schneider-Utaka AK, Reed ZW, Buckingham BA, Cobry E, DeBoer MD, Ekhlaspour L, Schoelwer M, Paul Wadwa R, Lum J, Kollman C, Beck RW, Breton MD. Patient reported outcomes (PROs) and user experiences of young children with type 1 diabetes using t:slim X2 insulin pump with control-IQ technology. Diabetes Res Clin Pract. 2024 Feb; 208:111114.
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Cobry EC, Pyle L, Karami AJ, Sakamoto C, Meltzer LJ, Jost E, Towers L, Paul Wadwa R. Impact of 6-months of an advanced hybrid closed-loop system on sleep and psychosocial outcomes in youth with type 1 diabetes and their parents. Diabetes Res Clin Pract. 2024 Jan; 207:111087.
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Suarez-Pierre A, Iguidbashian J, Kirsch MJ, Cain MT, Aftab M, Reece TB, Fullerton DA, Rove JY, Cleveland JC, Hoffman JRH. Association of cardiac preservation solution with short-term outcomes after heart transplantation. J Cardiovasc Med (Hagerstown). 2024 Feb 01; 25(2):158-164.
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Park J, Ntelis S, Yunasan E, Downton KD, Yip TC, Munir KM, Haq N. Glucagon-Like Peptide 1 Analogues as Adjunctive Therapy for Patients With Type 1 Diabetes: An Updated Systematic Review and Meta-analysis. J Clin Endocrinol Metab. 2023 Dec 21; 109(1):279-292.
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Greyslak KT, Hetrick B, Bergman BC, Dean TA, Wesolowski SR, Gannon M, Schenk S, Sullivan EL, Aagaard KM, Kievit P, Chicco AJ, Friedman JE, McCurdy CE. A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques. Diabetes. 2023 Dec 01; 72(12):1766-1780.
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Criego AB, Carlson AL, Brown SA, Forlenza GP, Bode BW, Levy CJ, Hansen DW, Hirsch IB, Bergenstal RM, Sherr JL, Mehta SN, Laffel LM, Shah VN, Bhargava A, Weinstock RS, MacLeish SA, DeSalvo DJ, Jones TC, Aleppo G, Buckingham BA, Ly TT. Two Years with a Tubeless Automated Insulin Delivery System: A Single-Arm Multicenter Trial in Children, Adolescents, and Adults with Type 1 Diabetes. Diabetes Technol Ther. 2024 Jan; 26(1):11-23.
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Moss ND, Wells KL, Theis A, Kim YK, Spigelman AF, Liu X, MacDonald PE, Sussel L. Modulation of insulin secretion by RBFOX2-mediated alternative splicing. Nat Commun. 2023 Nov 25; 14(1):7732.
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