 Multigene Family
"Multigene Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D005810
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| MeSH Number(s) |
G05.360.340.024.340.645
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| Concept/Terms |
Multigene Family- Multigene Family
- Families, Multigene
- Family, Multigene
- Multigene Families
Gene Clusters- Gene Clusters
- Cluster, Gene
- Clusters, Gene
- Gene Cluster
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Below are MeSH descriptors whose meaning is more general than "Multigene Family".
Below are MeSH descriptors whose meaning is more specific than "Multigene Family".
This graph shows the total number of publications written about "Multigene Family" by people in this website by year, and whether "Multigene Family" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 | | 1996 | 0 | 7 | 7 | | 1997 | 2 | 1 | 3 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 2 | 3 | | 2000 | 1 | 2 | 3 | | 2001 | 0 | 3 | 3 | | 2002 | 2 | 3 | 5 | | 2003 | 2 | 2 | 4 | | 2004 | 0 | 4 | 4 | | 2005 | 5 | 3 | 8 | | 2006 | 2 | 3 | 5 | | 2007 | 3 | 6 | 9 | | 2008 | 3 | 8 | 11 | | 2009 | 2 | 2 | 4 | | 2010 | 1 | 3 | 4 | | 2011 | 4 | 6 | 10 | | 2012 | 2 | 5 | 7 | | 2013 | 4 | 7 | 11 | | 2014 | 2 | 3 | 5 | | 2015 | 2 | 0 | 2 | | 2017 | 3 | 3 | 6 | | 2018 | 4 | 2 | 6 | | 2019 | 1 | 4 | 5 | | 2020 | 0 | 4 | 4 | | 2021 | 1 | 2 | 3 | | 2022 | 1 | 1 | 2 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Multigene Family" by people in Profiles.
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Raju RP, Cai L, Tyagi A, Pugazhenthi S. Interactions of Cellular Energetic Gene Clusters in the Alzheimer's Mouse Brain. Mol Neurobiol. 2024 Jan; 61(1):476-486.
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Egbert S, Hoffman JR, McMullin RT, Lendemer JC, Sorensen JL. Unraveling usnic acid: a comparison of biosynthetic gene clusters between two reindeer lichen (Cladonia rangiferina and C.?uncialis). Fungal Biol. 2022 Nov-Dec; 126(11-12):697-706.
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Cheng J, Clayton JS, Acemel RD, Zheng Y, Taylor RL, Keles S, Franke M, Boackle SA, Harley JB, Quail E, G?mez-Skarmeta JL, Ulgiati D. Regulatory Architecture of the RCA Gene Cluster Captures an Intragenic TAD Boundary, CTCF-Mediated Chromatin Looping and a Long-Range Intergenic Enhancer. Front Immunol. 2022; 13:901747.
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Nguyen NA, Cong Y, Hurrell RC, Arias N, Garg N, Puri AW, Schmidt EW, Agarwal V. A Silent Biosynthetic Gene Cluster from a Methanotrophic Bacterium Potentiates Discovery of a Substrate Promiscuous Proteusin Cyclodehydratase. ACS Chem Biol. 2022 06 17; 17(6):1577-1585.
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Yang C, Hallmark B, Chai JC, O'Connor TD, Reynolds LM, Wood AC, Seeds M, Chen YI, Steffen LM, Tsai MY, Kaplan RC, Daviglus ML, Mandarino LJ, Fretts AM, Lemaitre RN, Coletta DK, Blomquist SA, Johnstone LM, Tontsch C, Qi Q, Ruczinski I, Rich SS, Mathias RA, Chilton FH, Manichaikul A. Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations. Commun Biol. 2021 07 28; 4(1):918.
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Nguyen NA, Lin Z, Mohanty I, Garg N, Schmidt EW, Agarwal V. An Obligate Peptidyl Brominase Underlies the Discovery of Highly Distributed Biosynthetic Gene Clusters in Marine Sponge Microbiomes. J Am Chem Soc. 2021 07 14; 143(27):10221-10231.
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I?ca LP, Dai Y, Kunakom S, Diaz-Espinosa J, Krunic A, Crnkovic CM, Orjala J, Sanchez LM, Ferreira AG, Berlinck RGS, Eust?quio AS. A Family of Nonribosomal Peptides Modulate Collective Behavior in Pseudovibrio Bacteria Isolated from Marine Sponges*. Angew Chem Int Ed Engl. 2021 Jul 12; 60(29):15891-15898.
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Phukuntsi MA, Du Plessis M, Dalton DL, Jansen R, Sauther ML, Cuozzo FP, Kotze A. Population and genetic structure of a male-dispersing strepsirrhine, Galago moholi (Primates, Galagidae), from northern South Africa, inferred from mitochondrial DNA. Primates. 2021 Jul; 62(4):667-675.
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Santoriello FJ, Michel L, Unterweger D, Pukatzki S. Pandemic Vibrio cholerae shuts down site-specific recombination to retain an interbacterial defence mechanism. Nat Commun. 2020 12 07; 11(1):6246.
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Breuss MW, Mamerto A, Renner T, Waters ER. The Evolution of the Mammalian ABCA6-like Genes: Analysis of Phylogenetic, Expression, and Population Genetic Data Reveals Complex Evolutionary Histories. Genome Biol Evol. 2020 11 03; 12(11):2093-2106.
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