Glutathione
"Glutathione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
Descriptor ID |
D005978
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MeSH Number(s) |
D12.644.456.448
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Concept/Terms |
Glutathione- Glutathione
- gamma-L-Glutamyl-L-Cysteinylglycine
- gamma L Glutamyl L Cysteinylglycine
- gamma-L-Glu-L-Cys-Gly
- gamma L Glu L Cys Gly
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Below are MeSH descriptors whose meaning is more general than "Glutathione".
Below are MeSH descriptors whose meaning is more specific than "Glutathione".
This graph shows the total number of publications written about "Glutathione" by people in this website by year, and whether "Glutathione" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1996 | 1 | 2 | 3 | 1997 | 0 | 4 | 4 | 1998 | 0 | 4 | 4 | 1999 | 3 | 2 | 5 | 2000 | 3 | 3 | 6 | 2001 | 0 | 1 | 1 | 2002 | 2 | 4 | 6 | 2003 | 3 | 2 | 5 | 2004 | 4 | 6 | 10 | 2005 | 1 | 8 | 9 | 2006 | 2 | 8 | 10 | 2007 | 5 | 7 | 12 | 2008 | 2 | 4 | 6 | 2009 | 2 | 9 | 11 | 2010 | 4 | 5 | 9 | 2011 | 7 | 10 | 17 | 2012 | 4 | 7 | 11 | 2013 | 3 | 9 | 12 | 2014 | 1 | 1 | 2 | 2015 | 2 | 4 | 6 | 2016 | 2 | 6 | 8 | 2017 | 2 | 3 | 5 | 2018 | 4 | 6 | 10 | 2019 | 4 | 3 | 7 | 2020 | 1 | 5 | 6 | 2021 | 1 | 4 | 5 | 2022 | 0 | 3 | 3 | 2023 | 1 | 2 | 3 |
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Below are the most recent publications written about "Glutathione" by people in Profiles.
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Sri Hari A, Banerji R, Liang LP, Fulton RE, Huynh CQ, Fabisiak T, McElroy PB, Roede JR, Patel M. Increasing glutathione levels by a novel posttranslational mechanism inhibits neuronal hyperexcitability. Redox Biol. 2023 11; 67:102895.
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Kant S, Liu L, Vazquez-Torres A. The methylglyoxal pathway is a sink for glutathione in Salmonella experiencing oxidative stress. PLoS Pathog. 2023 06; 19(6):e1011441.
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Jin ES, Malloy CR, Sharma G, Finn E, Fuller KNZ, Reyes YG, Lovell MA, Derderian SC, Schoen JA, Inge TH, Cree MG. Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver. Redox Biol. 2023 07; 63:102749.
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Koza LA, Pena C, Russell M, Smith AC, Molnar J, Devine M, Serkova NJ, Linseman DA. Immunocal? limits gliosis in mouse models of repetitive mild-moderate traumatic brain injury. Brain Res. 2023 06 01; 1808:148338.
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Keller AC, Chun JH, Knaub LA, Henckel MM, Hull SE, Scalzo RL, Pott GB, Walker LA, Reusch JEB. Thermoneutrality induces vascular dysfunction and impaired metabolic function in male Wistar rats: a new model of vascular disease. J Hypertens. 2022 11 01; 40(11):2133-2146.
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Arnold CG, Dylla L, Monte AA, Heard K, Heard S, D'Alessandro A, Reynolds K, Dart R, Rumack B, Sonn B. Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences. J Med Toxicol. 2022 10; 18(4):297-310.
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Eroglu EC, Kucukgoz Gulec U, Vardar MA, Paydas S. GC-MS based metabolite fingerprinting of serous ovarian carcinoma and benign ovarian tumor. Eur J Mass Spectrom (Chichester). 2022 Feb; 28(1-2):12-24.
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van de Wetering C, Manuel AM, Sharafi M, Aboushousha R, Qian X, Erickson C, MacPherson M, Chan G, Adcock IM, ZounematKermani N, Schleich F, Louis R, Bohrnsen E, D'Alessandro A, Wouters EF, Reynaert NL, Li J, Wolf CR, Henderson CJ, Lundblad LKA, Poynter ME, Dixon AE, Irvin CG, van der Vliet A, van der Velden JL, Janssen-Heininger YM. Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2. Redox Biol. 2021 11; 47:102160.
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Chen Y, Wang Y, Charkoftaki G, Orlicky DJ, Davidson E, Wan F, Ginsberg G, Thompson DC, Vasiliou V. Oxidative stress and genotoxicity in 1,4-dioxane liver toxicity as evidenced in a mouse model of glutathione deficiency. Sci Total Environ. 2022 Feb 01; 806(Pt 2):150703.
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Thompson B, Chen Y, Davidson EA, Garcia-Milian R, Golla JP, Apostolopoulos N, Orlicky DJ, Schey K, Thompson DC, Vasiliou V. Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function. Ocul Surf. 2021 10; 22:190-203.
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