 Glutathione
"Glutathione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
| Descriptor ID |
D005978
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| MeSH Number(s) |
D12.644.456.448
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| Concept/Terms |
Glutathione- Glutathione
- gamma-L-Glutamyl-L-Cysteinylglycine
- gamma L Glutamyl L Cysteinylglycine
- gamma-L-Glu-L-Cys-Gly
- gamma L Glu L Cys Gly
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Below are MeSH descriptors whose meaning is more general than "Glutathione".
Below are MeSH descriptors whose meaning is more specific than "Glutathione".
This graph shows the total number of publications written about "Glutathione" by people in this website by year, and whether "Glutathione" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 4 | 4 | | 1999 | 3 | 2 | 5 | | 2000 | 2 | 3 | 5 | | 2001 | 0 | 1 | 1 | | 2002 | 5 | 8 | 13 | | 2003 | 3 | 2 | 5 | | 2004 | 4 | 8 | 12 | | 2005 | 1 | 9 | 10 | | 2006 | 2 | 10 | 12 | | 2007 | 5 | 7 | 12 | | 2008 | 2 | 4 | 6 | | 2009 | 3 | 9 | 12 | | 2010 | 4 | 8 | 12 | | 2011 | 8 | 11 | 19 | | 2012 | 4 | 9 | 13 | | 2013 | 3 | 10 | 13 | | 2014 | 0 | 2 | 2 | | 2015 | 2 | 3 | 5 | | 2016 | 1 | 6 | 7 | | 2017 | 3 | 4 | 7 | | 2018 | 2 | 5 | 7 | | 2019 | 2 | 4 | 6 | | 2020 | 1 | 6 | 7 | | 2021 | 1 | 4 | 5 | | 2022 | 0 | 5 | 5 | | 2023 | 1 | 5 | 6 | | 2024 | 2 | 2 | 4 | | 2025 | 3 | 3 | 6 | | 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Glutathione" by people in Profiles.
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Ling T, O'Brien C, St-Germain JR, Rondeau V, Shi M, Berman JM, Cepa A, Saez Raez P, Wunderlich M, Carter KM, Stillwell C, Sexton C, Culp-Hill R, Reisz JA, Adeel SA, Zeng AGX, Bansal S, Tsao E, Chen HT, Dick JE, Minden MD, Arruda A, Amaya ML, Tikhonova AN, Hope KJ, D'Alessandro A, Raught B, Jones CL. Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation. Blood. 2026 Feb 19; 147(8):863-876.
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Hossen F, Kouwaki T, Fujiwara Y, Tsutsuki H, Zhang T, Guo C, Rahman A, Komohara Y, Oshiumi H, Sawa T. Therapeutic Efficacy of the Supersulfide Donor NAC-S2 in Influenza Virus Pneumonia via Suppression of Excessive Inflammatory Responses. Microbiol Immunol. 2026 Mar; 70(3):148-159.
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Keele GR, Dzieciatkowska M, Hay AM, Vincent M, O'Connor C, Stephenson D, Reisz JA, Nemkov T, Hansen KC, Page GP, Zimring JC, Churchill GA, D'Alessandro A. Genetic architecture of the murine red blood cell proteome reveals central role of hemoglobin beta cysteine 93 in maintaining redox balance. Cell Genom. 2026 Mar 11; 6(3):101069.
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Nemkov T, Isiksacan Z, William N, Senturk R, Boudreau LE, Yarmush ML, Acker JP, D'Alessandro A, Usta OB. Supercooled storage of red blood cells slows down the metabolic storage lesion. Sci Rep. 2025 Oct 03; 15(1):34574.
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Sekela ME, Snyder EL, Welsby IJ, Toyoda Y, Alsammak M, Sodha NR, Beaver TM, Pelletier JPR, Gorham JD, McNeil JS, Sniecinski RM, Pearl RG, Nuttall GA, Sarode R, Reece TB, Benjamin RJ. Transfusion of Amustaline/Glutathione Pathogen-reduced Red Blood Cells in Cardiac Surgery: A Randomized Phase 3 Clinical Trial. Anesthesiology. 2025 Nov 01; 143(5):1196-1210.
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Prisciandaro JJ, Schacht JP, Prescot AP, Anton RF. Brain glutathione levels and associations with recent drinking in treatment-naïve individuals with alcohol use disorder versus light drinkers. Drug Alcohol Depend. 2025 Jul 01; 272:112705.
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Strand R, Orlicky DJ, Chen Y. Gene-dose effect of the glutathione biosynthesis gene on ascorbate deficiency in mice. Biochem Biophys Res Commun. 2025 06 20; 766:151900.
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Lesbats J, Brillac A, Reisz JA, Mukherjee P, Lhuissier C, Fernández-Monreal M, Dupuy JW, Sequeira A, Tioli G, De La Calle Arregui C, Pinson B, Wendisch D, Rousseau B, Efeyan A, Sander LE, D'Alessandro A, Garaude J. Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses. Nature. 2025 04; 640(8058):524-533.
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Muench NA, Schmitt HM, Schlamp CL, Su AA, Washington K, Nickells RW. Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations. Transl Vis Sci Technol. 2024 11 04; 13(11):24.
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Wang Y, Charkoftaki G, Orlicky DJ, Davidson E, Aalizadeh R, Sun N, Ginsberg G, Thompson DC, Vasiliou V, Chen Y. CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study. Arch Toxicol. 2024 10; 98(10):3241-3257.
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