 Glutathione
"Glutathione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
| Descriptor ID |
D005978
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| MeSH Number(s) |
D12.644.456.448
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| Concept/Terms |
Glutathione- Glutathione
- gamma-L-Glutamyl-L-Cysteinylglycine
- gamma L Glutamyl L Cysteinylglycine
- gamma-L-Glu-L-Cys-Gly
- gamma L Glu L Cys Gly
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Below are MeSH descriptors whose meaning is more general than "Glutathione".
Below are MeSH descriptors whose meaning is more specific than "Glutathione".
This graph shows the total number of publications written about "Glutathione" by people in this website by year, and whether "Glutathione" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 1 | 2 | 3 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 4 | 4 | | 1999 | 3 | 2 | 5 | | 2000 | 3 | 3 | 6 | | 2001 | 0 | 1 | 1 | | 2002 | 3 | 7 | 10 | | 2003 | 3 | 2 | 5 | | 2004 | 4 | 8 | 12 | | 2005 | 1 | 9 | 10 | | 2006 | 2 | 10 | 12 | | 2007 | 6 | 7 | 13 | | 2008 | 2 | 4 | 6 | | 2009 | 3 | 9 | 12 | | 2010 | 4 | 8 | 12 | | 2011 | 8 | 11 | 19 | | 2012 | 4 | 9 | 13 | | 2013 | 3 | 10 | 13 | | 2014 | 0 | 2 | 2 | | 2015 | 2 | 3 | 5 | | 2016 | 1 | 6 | 7 | | 2017 | 2 | 4 | 6 | | 2018 | 3 | 5 | 8 | | 2019 | 2 | 3 | 5 | | 2020 | 1 | 6 | 7 | | 2021 | 1 | 4 | 5 | | 2022 | 0 | 5 | 5 | | 2023 | 1 | 4 | 5 | | 2024 | 2 | 3 | 5 | | 2025 | 2 | 1 | 3 |
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Below are the most recent publications written about "Glutathione" by people in Profiles.
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Prisciandaro JJ, Schacht JP, Prescot AP, Anton RF. Brain glutathione levels and associations with recent drinking in treatment-naïve individuals with alcohol use disorder versus light drinkers. Drug Alcohol Depend. 2025 Jul 01; 272:112705.
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Strand R, Orlicky DJ, Chen Y. Gene-dose effect of the glutathione biosynthesis gene on ascorbate deficiency in mice. Biochem Biophys Res Commun. 2025 06 20; 766:151900.
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Lesbats J, Brillac A, Reisz JA, Mukherjee P, Lhuissier C, Fernández-Monreal M, Dupuy JW, Sequeira A, Tioli G, De La Calle Arregui C, Pinson B, Wendisch D, Rousseau B, Efeyan A, Sander LE, D'Alessandro A, Garaude J. Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses. Nature. 2025 Apr; 640(8058):524-533.
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Muench NA, Schmitt HM, Schlamp CL, Su AA, Washington K, Nickells RW. Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations. Transl Vis Sci Technol. 2024 11 04; 13(11):24.
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Wang Y, Charkoftaki G, Orlicky DJ, Davidson E, Aalizadeh R, Sun N, Ginsberg G, Thompson DC, Vasiliou V, Chen Y. CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study. Arch Toxicol. 2024 10; 98(10):3241-3257.
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Baker PR, Li AS, Griffin BR, Gil HW, Orlicky DJ, Fox BM, Park B, Sparagna GC, Goff J, Altmann C, Elajaili H, Okamura K, He Z, Stephenson D, D'Alessandro A, Reisz JA, Nozik ES, Sucharov CC, Faubel S. Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice. Sci Rep. 2024 06 15; 14(1):13862.
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Liang LP, Sri Hari A, Day BJ, Patel M. Pharmacological elevation of glutathione inhibits status epilepticus-induced neuroinflammation and oxidative injury. Redox Biol. 2024 07; 73:103168.
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Villa M, Sanin DE, Apostolova P, Corrado M, Kabat AM, Cristinzio C, Regina A, Carrizo GE, Rana N, Stanczak MA, Baixauli F, Grzes KM, Cupovic J, Solagna F, Hackl A, Globig AM, Hässler F, Puleston DJ, Kelly B, Cabezas-Wallscheid N, Hasselblatt P, Bengsch B, Zeiser R, Buescher JM, Pearce EJ, Pearce EL. Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment. Nat Commun. 2024 Jan 11; 15(1):451.
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Snyder EL, Sekela ME, Welsby IJ, Toyoda Y, Alsammak M, Sodha NR, Beaver TM, Pelletier JPR, Gorham JD, McNeil JS, Sniecinski RM, Pearl RG, Nuttall GA, Sarode R, Reece TB, Kaplan A, Davenport RD, Ipe TS, Benharash P, Lopez-Plaza I, Gammon RR, Sadler P, Pitman JP, Liu K, Bentow S, Corash L, Mufti N, Varrone J, Benjamin RJ. Evaluation of the efficacy and safety of amustaline/glutathione pathogen-reduced RBCs in complex cardiac surgery: the Red Cell Pathogen Inactivation (ReCePI) study-protocol for a phase 3, randomized, controlled trial. Trials. 2023 Dec 11; 24(1):799.
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Sri Hari A, Banerji R, Liang LP, Fulton RE, Huynh CQ, Fabisiak T, McElroy PB, Roede JR, Patel M. Increasing glutathione levels by a novel posttranslational mechanism inhibits neuronal hyperexcitability. Redox Biol. 2023 11; 67:102895.
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