 Renin
"Renin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
| Descriptor ID |
D012083
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| MeSH Number(s) |
D08.811.277.656.074.500.780 D08.811.277.656.300.048.780 D08.811.277.656.837.750
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| Concept/Terms |
Renin- Renin
- Angiotensin-Forming Enzyme
- Angiotensin Forming Enzyme
- Angiotensinogenase
Prorenin- Prorenin
- Inactive Renin
- Renin, Inactive
- Big Renin
- Renin, Big
- Cryorenin
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Below are MeSH descriptors whose meaning is more general than "Renin".
Below are MeSH descriptors whose meaning is more specific than "Renin".
This graph shows the total number of publications written about "Renin" by people in this website by year, and whether "Renin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 2 | 3 | | 2022 | 0 | 3 | 3 | | 2024 | 2 | 0 | 2 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Renin" by people in Profiles.
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Cárdenas P, Cid-Salinas C, León AC, Castillo-Geraldo J, de Oliveira LCG, Yokota R, Vallotton Z, Casarini DE, Prieto MC, Lorca RA, Gonzalez AA. (Pro)renin Receptor Blockade Prevents Increases in Systolic Blood Pressure, Sodium Retention, and aENaC Protein Expression in the Kidney of 2K1C Goldblatt Mice. Int J Mol Sci. 2025 Apr 28; 26(9).
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Busse LW, Teixeira JP, Schaich CL, Ten Lohuis CC, Nielsen ND, Sturek JM, Merck LH, Self WH, Puskarich MA, Khan A, Semler MW, Moskowitz A, Hager DN, Duggal A, Rice TW, Ginde AA, Tiffany BR, Iovine NM, Chen P, Safdar B, Gibbs KW, Javaheri A, de Wit M, Harkins MS, Joly MM, Collins SP. Shock prediction with dipeptidyl peptidase-3 and renin (SPiDeR) in hypoxemic patients with COVID-19. J Crit Care. 2025 Feb; 85:154950.
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Kim ME, Gist KM, Brandewie K, Zang H, Lehenbauer D, Winlaw DS, Morales DLS, Alten JA, Goldstein SL, Cooper DS. Kinetics of Renin Concentrations in Infants Undergoing Congenital Cardiac Surgery. J Intensive Care Med. 2025 02; 40(2):172-177.
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Hinds DM, Nick HJ, Vallin TM, Bloomquist LA, Christeson S, Bratcher PE, Cooper EH, Brinton JT, Bosco-Lauth A, White CW. Acute vaping in a golden Syrian hamster causes inflammatory response transcriptomic changes. Am J Physiol Lung Cell Mol Physiol. 2022 11 01; 323(5):L525-L535.
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Sen T, Scholtes R, Greasley PJ, Cherney DZI, Dekkers CCJ, Vervloet M, Danser AHJ, Barbour SJ, Karlsson C, Hammarstedt A, Li Q, Laverman GD, Bjornstad P, van Raalte DH, Heerspink HJL. Effects of dapagliflozin on volume status and systemic haemodynamics in patients with chronic kidney disease without diabetes: Results from DAPASALT and DIAMOND. Diabetes Obes Metab. 2022 08; 24(8):1578-1587.
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Rizzolo K, Beck NM, Ambruso SL. Syndromes of Pseudo-Hyperaldosteronism. Clin J Am Soc Nephrol. 2022 04; 17(4):581-584.
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Piani F, Reinicke T, Lytvyn Y, Melena I, Lovblom LE, Lai V, Tse J, Cham L, Orszag A, Perkins BA, Cherney DZI, Bjornstad P. Vasopressin associated with renal vascular resistance in adults with longstanding type 1 diabetes with and without diabetic kidney disease. J Diabetes Complications. 2021 03; 35(3):107807.
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Chow JH, Wallis M, Lankford AS, Chancer Z, Barth RN, Scalea JR, LaMattina JC, Mazzeffi MA, McCurdy MT. Treatment of Renin-Angiotensin-Aldosterone System Dysfunction With Angiotensin II in High-Renin Septic Shock. Semin Cardiothorac Vasc Anesth. 2021 Mar; 25(1):67-73.
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Charlton GA, Ladd DR, Friesen RM, Friesen RH. Labetalol Infusion Attenuates Paradoxical Hypertension and Decreases Plasma Renin Activity After Repair of Coarctation of the Aorta in Children. J Cardiothorac Vasc Anesth. 2020 Dec; 34(12):3348-3351.
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Weaver J, Rove KO, Vricella GJ. Extra-adrenal Pheochromocytoma Associated With Segmental Renal Artery Compression and Pseudostenosis. Urology. 2018 Oct; 120:238-240.
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