 Guanine Nucleotide Exchange Factors
"Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.
| Descriptor ID |
D020662
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| MeSH Number(s) |
D12.644.360.325.300 D12.776.476.325.300
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| Concept/Terms |
Guanine Nucleotide Exchange Factors- Guanine Nucleotide Exchange Factors
- Guanine-Nucleotide-Releasing Factor
- Guanine Nucleotide Releasing Factor
- GDP Dissociation Factor
- GDP-GTP Exchange Protein
- GDP GTP Exchange Protein
- GDP Dissociation Stimulators
- GDP-GTP Reversing Factors
- Factors, GDP-GTP Reversing
- GDP GTP Reversing Factors
- Reversing Factors, GDP-GTP
- Guanine Nucleotide Releasing Factors
- GDP Exchange Factors
- Exchange Factors, GDP
- Factors, GDP Exchange
- Guanine Nucleotide Exchange Factor
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Below are MeSH descriptors whose meaning is more general than "Guanine Nucleotide Exchange Factors".
Below are MeSH descriptors whose meaning is more specific than "Guanine Nucleotide Exchange Factors".
This graph shows the total number of publications written about "Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "Guanine Nucleotide Exchange Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 2002 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 3 | 0 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 3 | 0 | 3 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 4 | 1 | 5 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 4 | 1 | 5 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 2 | 3 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2024 | 0 | 2 | 2 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanine Nucleotide Exchange Factors" by people in Profiles.
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Cooperman B, McMurray M. Roles for the canonical polarity machinery in the de novo establishment of polarity in budding yeast spores. Mol Biol Cell. 2025 Mar 01; 36(3):ar28.
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Banks E, Francis V, Lin SJ, Kharfallah F, Fonov V, Lévesque M, Han C, Kulasekaran G, Tuznik M, Bayati A, Al-Khater R, Alkuraya FS, Argyriou L, Babaei M, Bahlo M, Bakhshoodeh B, Barr E, Bartik L, Bassiony M, Bertrand M, Braun D, Buchert R, Budetta M, Cadieux-Dion M, Calame DG, Cope H, Cushing D, Efthymiou S, Elmaksoud MA, El Said HG, Froukh T, Gill HK, Gleeson JG, Gogoll L, Goh ES, Gowda VK, Haack TB, Hashem MO, Hauser S, Hoffman TL, Hogue JS, Hosokawa A, Houlden H, Huang K, Huynh S, Karimiani EG, Kaulfuß S, Korenke GC, Kritzer A, Lee H, Lupski JR, Marco EJ, McWalter K, Minassian A, Minassian BA, Murphy D, Neira-Fresneda J, Northrup H, Nyaga DM, Oehl-Jaschkowitz B, Osmond M, Person R, Pehlivan D, Petree C, Sadleir LG, Saunders C, Schoels L, Shashi V, Spillmann RC, Srinivasan VM, Torbati PN, Tos T, Zaki MS, Zhou D, Zweier C, Trempe JF, Durcan TM, Gan-Or Z, Avoli M, Alves C, Varshney GK, Maroofian R, Rudko DA, McPherson PS. Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. Nat Commun. 2024 Aug 22; 15(1):7239.
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Binti S, Linder AG, Edeen PT, Fay DS. A conserved protein tyrosine phosphatase, PTPN-22, functions in diverse developmental processes in C. elegans. PLoS Genet. 2024 Aug; 20(8):e1011219.
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Krishnan A, Bhasker AI, Singh MK, Rodriguez CI, P?rez EC, Altameemi S, Lares M, Khan H, Ndiaye M, Ahmad N, Schieke SM, Setaluri V. EPAC Regulates Melanoma Growth by Stimulating mTORC1 Signaling and Loss of EPAC Signaling Dependence Correlates with Melanoma Progression. Mol Cancer Res. 2022 10 04; 20(10):1548-1560.
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Weliwitigoda A, Palle P, Gessner M, Hubbard NW, Oukka M, Bettelli E. Cutting Edge: DOCK8 Regulates a Subset of Dendritic Cells That Is Critical for the Development of Experimental Autoimmune Encephalomyelitis. J Immunol. 2021 11 15; 207(10):2417-2422.
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Schultz-Rogers L, Muthusamy K, Pinto E Vairo F, Klee EW, Lanpher B. Novel loss-of-function variants in TRIO are associated with neurodevelopmental disorder: case report. BMC Med Genet. 2020 11 10; 21(1):219.
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Eken A, Cansever M, Okus FZ, Erdem S, Nain E, Azizoglu ZB, Haliloglu Y, Karakukcu M, Ozcan A, Devecioglu O, Aksu G, Arikan Ayyildiz Z, Topal E, Karakoc Aydiner E, Kiykim A, Metin A, Cipe F, Kaya A, Artac H, Reisli I, Guner SN, Uygun V, Karasu G, D?nmez Altuntas H, Canatan H, Oukka M, Ozen A, Chatila TA, Keles S, Baris S, Unal E, Patiroglu T. ILC3 deficiency and generalized ILC abnormalities in DOCK8-deficient patients. Allergy. 2020 04; 75(4):921-932.
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Stearman RS, Cornelius AR, Young LR, Conklin DS, Mickler EA, Lu X, Hara N, Fettig LM, Phang TL, Geraci MW. Familial Pulmonary Fibrosis and Hermansky-Pudlak Syndrome Rare Missense Mutations in Context. Am J Respir Crit Care Med. 2019 07 15; 200(2):253-256.
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Strassheim D, Gerasimovskaya E, Irwin D, Dempsey EC, Stenmark K, Karoor V. RhoGTPase in Vascular Disease. Cells. 2019 06 06; 8(6).
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Jones KA, Sumiya M, Woolfrey KM, Srivastava DP, Penzes P. Loss of EPAC2 alters dendritic spine morphology and inhibitory synapse density. Mol Cell Neurosci. 2019 07; 98:19-31.
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