Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Jay Hesselberth

Concepts (398)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Saccharomyces cerevisiae
17
2025
556
2.710
Why?
Sequence Analysis, RNA
10
2025
452
2.150
Why?
Saccharomyces cerevisiae Proteins
9
2023
404
1.860
Why?
Single-Cell Analysis
10
2025
311
1.750
Why?
RNA Splicing
4
2019
268
1.490
Why?
DNA Repair
4
2020
231
1.280
Why?
RNA, Messenger
16
2025
2831
1.260
Why?
RNA
7
2023
921
1.220
Why?
RNA, Transfer
3
2025
138
1.200
Why?
Basic-Leucine Zipper Transcription Factors
2
2019
41
1.170
Why?
RNA Stability
5
2025
117
1.030
Why?
Aminoacylation
1
2025
14
0.970
Why?
High-Throughput Nucleotide Sequencing
9
2020
535
0.950
Why?
Repressor Proteins
2
2019
427
0.920
Why?
Unfolded Protein Response
4
2019
59
0.890
Why?
Sequence Analysis, DNA
5
2020
809
0.860
Why?
Introns
5
2017
256
0.720
Why?
RNA Ligase (ATP)
3
2017
6
0.710
Why?
Gene Expression Regulation, Fungal
3
2019
72
0.690
Why?
Endoribonucleases
3
2015
80
0.670
Why?
RNA Cleavage
2
2015
10
0.590
Why?
Phosphorylation
1
2023
1758
0.580
Why?
Phosphotransferases (Alcohol Group Acceptor)
1
2017
45
0.570
Why?
DNA
3
2021
1458
0.560
Why?
Protein Interaction Mapping
3
2010
109
0.560
Why?
Cell Cycle Proteins
2
2017
613
0.530
Why?
RNA Precursors
4
2014
154
0.520
Why?
Gene Expression
3
2020
1500
0.510
Why?
Base Sequence
11
2015
2179
0.480
Why?
Transcriptome
4
2022
969
0.470
Why?
RNA Nucleotidyltransferases
2
2014
21
0.460
Why?
Pyrimidine Dimers
1
2014
6
0.450
Why?
DNA Repair Enzymes
1
2014
28
0.440
Why?
RNA, Catalytic
5
2004
187
0.440
Why?
MicroRNAs
4
2016
692
0.360
Why?
Alternative Splicing
1
2013
229
0.360
Why?
RNA, Long Noncoding
1
2013
181
0.350
Why?
Lymph Nodes
3
2024
492
0.340
Why?
Saccharomyces
1
2010
8
0.340
Why?
Chimera
1
2010
58
0.340
Why?
Molecular Sequence Data
12
2015
2894
0.320
Why?
B-Lymphocytes
2
2025
846
0.320
Why?
DNA Footprinting
1
2009
33
0.310
Why?
Peptides
2
2025
981
0.310
Why?
Spliceosomes
3
2014
48
0.310
Why?
Nucleosomes
1
2010
155
0.290
Why?
Biosensing Techniques
4
2006
122
0.280
Why?
CD8-Positive T-Lymphocytes
2
2025
913
0.280
Why?
Binding Sites
6
2018
1301
0.270
Why?
Uracil
2
2018
31
0.270
Why?
DNA Replication
3
2017
238
0.270
Why?
Software
4
2021
665
0.270
Why?
Models, Genetic
4
2010
599
0.250
Why?
Oligonucleotides
3
2004
148
0.250
Why?
Protein Array Analysis
1
2006
57
0.250
Why?
Hibernation
2
2018
75
0.250
Why?
Ligases
2
2003
32
0.250
Why?
Polyadenylation
2
2017
42
0.250
Why?
Computational Biology
4
2021
643
0.240
Why?
Chikungunya Fever
2
2024
79
0.240
Why?
Immunologic Memory
2
2025
370
0.240
Why?
Blotting, Northern
1
2025
200
0.240
Why?
Promoter Regions, Genetic
1
2010
1249
0.240
Why?
Nonsense Mediated mRNA Decay
1
2025
16
0.230
Why?
Codon, Nonsense
1
2025
44
0.230
Why?
Genome, Fungal
3
2017
40
0.230
Why?
Amino Acid Sequence
4
2025
2138
0.230
Why?
Cell Differentiation
4
2023
1982
0.230
Why?
Nucleotides
1
2025
125
0.230
Why?
Exons
2
2017
351
0.220
Why?
Endothelial Cells
5
2024
778
0.220
Why?
Transcription Factors
3
2023
1718
0.210
Why?
Protein Binding
7
2020
2216
0.210
Why?
RNA, Small Nuclear
3
2014
37
0.210
Why?
Gene Library
3
2019
116
0.210
Why?
Mutation
7
2020
3947
0.210
Why?
Genetic Techniques
3
2015
64
0.210
Why?
Gene Expression Profiling
6
2021
1772
0.200
Why?
RNA, Viral
3
2021
654
0.200
Why?
Yeasts
2
2018
53
0.200
Why?
Signal Transduction
5
2020
5077
0.200
Why?
Viral Proteins
1
2025
340
0.200
Why?
Chikungunya virus
1
2024
80
0.200
Why?
Animals
20
2025
36850
0.190
Why?
Stress, Physiological
1
2025
441
0.190
Why?
Escherichia coli
2
2018
807
0.190
Why?
Gain of Function Mutation
1
2021
36
0.180
Why?
Haploinsufficiency
1
2021
56
0.180
Why?
Mice
11
2025
17759
0.180
Why?
Alphavirus Infections
1
2021
44
0.180
Why?
Replication Origin
2
2017
19
0.180
Why?
Immunoprecipitation
3
2016
155
0.180
Why?
Lymphocyte Activation
1
2025
1150
0.170
Why?
Gene Editing
1
2021
79
0.170
Why?
Murine hepatitis virus
1
2020
16
0.170
Why?
Viremia
1
2021
138
0.170
Why?
RNA, Small Cytoplasmic
1
2020
7
0.170
Why?
Mice, Inbred C57BL
8
2025
5750
0.170
Why?
Ricin
1
2000
8
0.170
Why?
Receptors, Immunologic
1
2021
216
0.170
Why?
Machine Learning
1
2025
488
0.170
Why?
Sensitivity and Specificity
4
2016
1936
0.170
Why?
Sequence Alignment
2
2014
342
0.160
Why?
Viral Nonstructural Proteins
1
2020
65
0.160
Why?
rac GTP-Binding Proteins
1
2020
32
0.160
Why?
Cerebellar Neoplasms
1
2022
152
0.160
Why?
Mouse Embryonic Stem Cells
1
2020
30
0.160
Why?
Cluster Analysis
2
2019
497
0.160
Why?
Neoplastic Cells, Circulating
1
2020
80
0.160
Why?
Medulloblastoma
1
2022
193
0.160
Why?
Extracellular Fluid
1
2019
31
0.160
Why?
Genetic Therapy
1
2021
293
0.160
Why?
rho GTP-Binding Proteins
1
2020
60
0.160
Why?
Cell Line
4
2020
2838
0.160
Why?
Integrins
1
2020
95
0.160
Why?
Antigens
1
2021
358
0.150
Why?
Myeloid-Lymphoid Leukemia Protein
1
2020
69
0.150
Why?
DNA, Single-Stranded
1
2000
118
0.150
Why?
Hematopoiesis
1
2020
190
0.150
Why?
DNA, Complementary
1
2019
271
0.150
Why?
RNA Editing
1
2018
24
0.150
Why?
Exoribonucleases
1
2019
49
0.150
Why?
Thymocytes
1
2018
35
0.150
Why?
Ependymoma
1
2020
165
0.150
Why?
Tunicamycin
1
2017
12
0.140
Why?
Bleomycin
1
2019
247
0.140
Why?
Alveolar Epithelial Cells
1
2019
114
0.140
Why?
Chromatids
1
2017
9
0.140
Why?
Substrate Specificity
2
2017
371
0.140
Why?
Lymphocytes
1
2020
393
0.140
Why?
Histone-Lysine N-Methyltransferase
1
2020
135
0.140
Why?
Cells, Cultured
7
2021
4192
0.140
Why?
Natural Killer T-Cells
1
2018
67
0.140
Why?
Azacitidine
1
2018
140
0.140
Why?
Precision Medicine
1
2021
426
0.140
Why?
Meiosis
1
2017
81
0.140
Why?
Epilepsy
1
2021
331
0.140
Why?
Superoxide Dismutase
1
2019
346
0.140
Why?
Autoantibodies
1
2025
1496
0.130
Why?
Hepatitis C, Chronic
1
2019
164
0.130
Why?
Regeneration
1
2019
195
0.130
Why?
Ligands
4
2006
661
0.130
Why?
Mutagenesis
1
2017
179
0.130
Why?
RNA-Binding Proteins
2
2016
423
0.130
Why?
Bridged Bicyclo Compounds, Heterocyclic
1
2018
227
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2007
766
0.130
Why?
DNA, Mitochondrial
2
2015
200
0.130
Why?
Humans
28
2025
136803
0.130
Why?
Mammals
1
2018
283
0.130
Why?
Recombination, Genetic
1
2017
200
0.130
Why?
Host-Pathogen Interactions
2
2021
363
0.130
Why?
Macrophages, Alveolar
1
2019
391
0.130
Why?
Virus Integration
1
2016
71
0.130
Why?
Membrane Glycoproteins
1
2019
500
0.130
Why?
Transforming Growth Factor beta
1
2019
480
0.130
Why?
Lung Injury
1
2019
218
0.130
Why?
Leukocytes, Mononuclear
1
2019
558
0.120
Why?
Macrophages
3
2021
1544
0.120
Why?
RNA, Fungal
2
2014
72
0.120
Why?
Phenotype
3
2020
3189
0.120
Why?
T-Lymphocyte Subsets
1
2018
425
0.120
Why?
Nucleic Acid Conformation
3
2013
728
0.120
Why?
Non-alcoholic Fatty Liver Disease
1
2019
279
0.120
Why?
Carcinogenesis
1
2017
217
0.120
Why?
Gene Expression Regulation
2
2018
2605
0.120
Why?
Artifacts
1
2016
129
0.120
Why?
Extracellular Matrix
1
2019
528
0.120
Why?
Amino Acyl-tRNA Synthetases
1
2015
30
0.120
Why?
Temperature
1
2018
675
0.120
Why?
Mitochondrial Proteins
1
2017
256
0.120
Why?
3-Hydroxyacyl CoA Dehydrogenases
1
2015
9
0.120
Why?
Acetyl-CoA C-Acetyltransferase
1
2015
9
0.120
Why?
Ribonucleotides
1
2015
26
0.120
Why?
DNA Damage
1
2018
420
0.120
Why?
Ultraviolet Rays
1
2018
390
0.120
Why?
Lipid Metabolism, Inborn Errors
1
2015
19
0.120
Why?
Brain
2
2018
2664
0.110
Why?
Genomics
1
2020
790
0.110
Why?
Sulfonamides
1
2018
513
0.110
Why?
Thermogenesis
1
2015
44
0.110
Why?
Cytoskeletal Proteins
1
2015
156
0.110
Why?
Catalysis
2
2014
307
0.110
Why?
Protein Biosynthesis
3
2002
430
0.110
Why?
Adipose Tissue, Brown
1
2015
53
0.110
Why?
DNA, Viral
1
2016
363
0.110
Why?
Neoplastic Stem Cells
1
2018
399
0.110
Why?
Ribonuclease, Pancreatic
1
2014
12
0.110
Why?
Receptors, Antigen, T-Cell
1
2018
718
0.110
Why?
Influenza A virus
1
2014
110
0.110
Why?
RNA, Small Nucleolar
1
2013
9
0.110
Why?
Breast Neoplasms
2
2017
2234
0.100
Why?
Apoptosis
2
2019
2552
0.100
Why?
Drosophila Proteins
1
2015
205
0.100
Why?
Drosophila melanogaster
1
2015
233
0.100
Why?
Escherichia coli Proteins
1
2015
194
0.100
Why?
Ribonucleoprotein, U5 Small Nuclear
1
2013
11
0.100
Why?
Nucleic Acids
2
2006
71
0.100
Why?
Ribonucleoprotein, U4-U6 Small Nuclear
1
2013
11
0.100
Why?
Liver
2
2019
1940
0.100
Why?
Eukaryota
1
2013
57
0.100
Why?
Energy Metabolism
2
2018
919
0.100
Why?
Bone Marrow Cells
1
2014
316
0.100
Why?
Receptors, Cytoplasmic and Nuclear
1
2014
219
0.100
Why?
Caenorhabditis elegans Proteins
1
2014
198
0.100
Why?
Mitochondria
2
2017
946
0.090
Why?
Leukemia, Myeloid, Acute
1
2018
622
0.090
Why?
Genome, Human
1
2014
423
0.090
Why?
Nerve Tissue Proteins
1
2015
595
0.090
Why?
Evolution, Molecular
2
2018
488
0.090
Why?
Adipose Tissue
1
2015
630
0.090
Why?
Mice, Transgenic
3
2021
2163
0.090
Why?
Protein Footprinting
1
2010
11
0.090
Why?
AT Rich Sequence
1
2010
4
0.090
Why?
HIV-1
1
2016
863
0.080
Why?
DNA-Binding Proteins
1
2017
1501
0.080
Why?
Transcription, Genetic
2
2015
1455
0.080
Why?
Protein Structure, Tertiary
3
2006
860
0.080
Why?
DNA Methylation
1
2014
640
0.080
Why?
Inflammation
1
2019
2835
0.070
Why?
Diabetes Mellitus, Type 1
1
2025
3710
0.070
Why?
Nucleotide Motifs
2
2020
35
0.070
Why?
DNA Primers
2
2016
514
0.070
Why?
Amino Acids
1
2010
497
0.060
Why?
Neurons
1
2015
1587
0.060
Why?
Two-Hybrid System Techniques
1
2005
59
0.060
Why?
Plasmodium falciparum
1
2005
30
0.060
Why?
Malaria, Falciparum
1
2005
27
0.060
Why?
Amino Acid Motifs
1
2006
225
0.060
Why?
Peptide Chain Termination, Translational
1
2025
9
0.060
Why?
Codon, Terminator
1
2025
25
0.060
Why?
Sciuridae
2
2018
147
0.060
Why?
Protozoan Proteins
1
2005
82
0.060
Why?
Forkhead Box Protein O1
1
2025
33
0.060
Why?
Toll-Like Receptors
1
2006
185
0.060
Why?
Metabolomics
1
2010
678
0.060
Why?
Algorithms
2
2010
1690
0.060
Why?
Receptors, Antigen, B-Cell
1
2025
130
0.060
Why?
Models, Biological
2
2015
1773
0.050
Why?
Mutation, Missense
1
2006
337
0.050
Why?
Databases, Nucleic Acid
1
2004
34
0.050
Why?
Reverse Transcription
2
2016
20
0.050
Why?
Gene Expression Regulation, Neoplastic
2
2022
1396
0.050
Why?
Genetic Engineering
1
2004
91
0.050
Why?
Thiamine Pyrophosphate
1
2002
3
0.050
Why?
Adaptor Proteins, Signal Transducing
1
2006
429
0.050
Why?
Cobamides
1
2002
20
0.050
Why?
Feedback, Physiological
1
2002
77
0.050
Why?
Listeria monocytogenes
1
2023
126
0.050
Why?
Biological Evolution
1
2006
467
0.050
Why?
Phylogeny
1
2006
903
0.050
Why?
Alphavirus
1
2021
21
0.050
Why?
Kupffer Cells
1
2021
50
0.050
Why?
Immunization
1
2024
411
0.050
Why?
Phosphorothioate Oligonucleotides
1
2021
11
0.040
Why?
Caveolae
1
2021
17
0.040
Why?
Oligonucleotides, Antisense
1
2021
111
0.040
Why?
Peptide Fragments
2
2021
705
0.040
Why?
Mice, Mutant Strains
1
2021
298
0.040
Why?
Metadata
1
2021
14
0.040
Why?
Ovalbumin
1
2021
183
0.040
Why?
Female
7
2025
72816
0.040
Why?
Hedgehog Proteins
1
2022
195
0.040
Why?
Tissue Distribution
1
2021
330
0.040
Why?
Epithelial Cells
2
2014
1094
0.040
Why?
Embryoid Bodies
1
2020
8
0.040
Why?
Meta-Analysis as Topic
1
2021
186
0.040
Why?
Endocytosis
1
2021
169
0.040
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2016
975
0.040
Why?
Colony-Forming Units Assay
1
2020
91
0.040
Why?
Antigen Presentation
1
2021
216
0.040
Why?
Molecular Conformation
1
2000
145
0.040
Why?
Male
6
2025
67330
0.040
Why?
Tricarboxylic Acids
1
2018
10
0.040
Why?
beta-Defensins
1
1998
21
0.040
Why?
Ketoglutaric Acids
1
2018
16
0.040
Why?
Antibodies
1
2001
411
0.040
Why?
Protein Structure, Secondary
1
2000
374
0.040
Why?
Mesoderm
1
2020
144
0.040
Why?
Antibiotics, Antineoplastic
1
2019
127
0.040
Why?
Lipoproteins, LDL
1
2019
116
0.040
Why?
Electron Transport Complex II
1
2018
26
0.040
Why?
Succinate Dehydrogenase
1
2018
50
0.040
Why?
Islets of Langerhans
1
2025
803
0.040
Why?
Early Growth Response Protein 2
1
2018
10
0.040
Why?
Lymphatic Vessels
1
2019
64
0.040
Why?
Torpor
1
2018
14
0.040
Why?
Primary Cell Culture
1
2019
171
0.040
Why?
Cell Adhesion
1
2020
466
0.040
Why?
In Vitro Techniques
1
2000
1089
0.040
Why?
NFATC Transcription Factors
1
2018
95
0.040
Why?
Loss of Function Mutation
1
2017
46
0.030
Why?
Dendritic Cells
1
2021
484
0.030
Why?
Oxidative Phosphorylation
1
2018
193
0.030
Why?
Tumor Microenvironment
1
2022
672
0.030
Why?
G1 Phase
1
2017
71
0.030
Why?
S Phase
1
2017
77
0.030
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
233
0.030
Why?
MCF-7 Cells
1
2017
124
0.030
Why?
3' Untranslated Regions
1
2017
145
0.030
Why?
Aged, 80 and over
2
2019
7593
0.030
Why?
Fibrosis
1
2019
552
0.030
Why?
Hematopoietic Stem Cells
1
2020
402
0.030
Why?
Proteins
1
2002
1009
0.030
Why?
Disease-Free Survival
1
2017
686
0.030
Why?
Mice, Inbred BALB C
1
2018
1269
0.030
Why?
Crosses, Genetic
1
2015
137
0.030
Why?
Lipopolysaccharides
1
2019
886
0.030
Why?
Uracil-DNA Glycosidase
1
2015
1
0.030
Why?
GC Rich Sequence
1
2015
4
0.030
Why?
Gas Chromatography-Mass Spectrometry
1
2015
132
0.030
Why?
Dyskinesias
1
2015
19
0.030
Why?
Molecular Sequence Annotation
1
2015
97
0.030
Why?
Cell Respiration
1
2015
102
0.030
Why?
DNA, Fungal
1
2015
80
0.030
Why?
Electron Transport
1
2015
115
0.030
Why?
Body Size
1
2015
108
0.030
Why?
Hydrolysis
1
2014
176
0.030
Why?
Reactive Oxygen Species
1
2017
621
0.030
Why?
Larva
1
2015
224
0.030
Why?
Serrate-Jagged Proteins
1
2014
27
0.030
Why?
Jagged-1 Protein
1
2014
23
0.030
Why?
Argonaute Proteins
1
2014
27
0.030
Why?
Receptors, Steroid
1
2014
50
0.030
Why?
Wnt-5a Protein
1
2014
23
0.030
Why?
Arousal
1
2015
155
0.030
Why?
RNA Processing, Post-Transcriptional
1
2015
92
0.030
Why?
Matrix Metalloproteinase 2
1
2014
56
0.030
Why?
Body Temperature
1
2015
221
0.030
Why?
Gene Knockdown Techniques
1
2014
327
0.030
Why?
Muscles
1
2015
325
0.030
Why?
Stromal Cells
1
2014
112
0.030
Why?
Chromatin
1
2017
519
0.030
Why?
Cellular Microenvironment
1
2014
84
0.030
Why?
Poliovirus
1
2014
85
0.030
Why?
Neoplasm Grading
1
2014
305
0.030
Why?
RNA, Ribosomal
1
2014
168
0.030
Why?
Ribonucleoproteins, Small Nuclear
1
2013
24
0.030
Why?
Wnt Proteins
1
2014
133
0.030
Why?
Chronic Disease
1
2019
1786
0.030
Why?
Child
2
2025
21819
0.020
Why?
Calcium-Binding Proteins
1
2014
218
0.020
Why?
Base Pairing
2
2004
63
0.020
Why?
RNA Interference
1
2014
466
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2014
382
0.020
Why?
HeLa Cells
1
2014
633
0.020
Why?
Hepacivirus
1
2014
261
0.020
Why?
Gene Regulatory Networks
1
2014
304
0.020
Why?
Virus Replication
1
2014
482
0.020
Why?
Polymorphism, Single Nucleotide
1
2019
2184
0.020
Why?
Down-Regulation
1
2014
656
0.020
Why?
Receptors, Estrogen
1
2014
436
0.020
Why?
Estrogens
1
2014
368
0.020
Why?
Caenorhabditis elegans
1
2014
305
0.020
Why?
Vascular Endothelial Growth Factor A
1
2014
543
0.020
Why?
Proto-Oncogene Proteins
1
2014
647
0.020
Why?
Transcription Initiation Site
1
2010
43
0.020
Why?
Gene Expression Regulation, Developmental
1
2015
858
0.020
Why?
Carrier Proteins
1
2014
769
0.020
Why?
Rats
1
2019
5639
0.020
Why?
Time Factors
1
2021
6809
0.020
Why?
Brain Chemistry
1
2010
116
0.020
Why?
Myocardium
1
2015
1001
0.020
Why?
Adult
2
2025
37643
0.020
Why?
Aged
2
2019
23808
0.020
Why?
Organophosphates
1
2010
134
0.020
Why?
Arabidopsis
1
2010
95
0.020
Why?
Cloning, Molecular
1
2010
534
0.020
Why?
Gene Deletion
1
2010
389
0.020
Why?
Disease Models, Animal
1
2019
4282
0.020
Why?
Biomarkers
1
2020
4145
0.020
Why?
Bayes Theorem
1
2010
404
0.020
Why?
Genome
1
2010
294
0.020
Why?
Membrane Proteins
1
2014
1163
0.020
Why?
Lung
1
2019
4063
0.020
Why?
Cell Line, Tumor
1
2014
3406
0.020
Why?
Chaperonin 60
1
2006
14
0.020
Why?
Severity of Illness Index
1
2014
2822
0.020
Why?
Aptamers, Nucleotide
1
2006
83
0.020
Why?
Adolescent
1
2025
21385
0.020
Why?
Prognosis
1
2014
4013
0.020
Why?
Myeloid Differentiation Factor 88
1
2006
99
0.010
Why?
Genetic Variation
1
2010
985
0.010
Why?
Virulence Factors
1
2005
166
0.010
Why?
Infant, Newborn
1
2015
6032
0.010
Why?
Biotinylation
1
2002
32
0.010
Why?
Ribonucleoprotein, U1 Small Nuclear
1
2002
13
0.010
Why?
Automation
1
2002
95
0.010
Why?
HIV Infections
1
2016
2828
0.010
Why?
Directed Molecular Evolution
1
2001
21
0.010
Why?
Infant
1
2015
9395
0.010
Why?
Defensins
1
1998
4
0.010
Why?
Internet
1
2004
647
0.010
Why?
Reproducibility of Results
1
2007
3265
0.010
Why?
In Situ Hybridization
1
1998
316
0.010
Why?
Respiratory System
1
1998
157
0.010
Why?
Middle Aged
1
2019
33239
0.010
Why?
Models, Molecular
1
2001
1570
0.010
Why?
Interleukin-1
1
1998
964
0.010
Why?
Hesselberth's Networks
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