Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Jay Hesselberth

Concepts (387)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Saccharomyces cerevisiae
16
2023
530
2.620
Why?
Saccharomyces cerevisiae Proteins
9
2023
383
1.920
Why?
Single-Cell Analysis
10
2025
274
1.800
Why?
RNA Splicing
4
2019
259
1.510
Why?
Sequence Analysis, RNA
9
2021
426
1.410
Why?
DNA Repair
4
2020
210
1.320
Why?
RNA, Messenger
15
2023
2703
1.280
Why?
RNA
7
2023
877
1.260
Why?
Basic-Leucine Zipper Transcription Factors
2
2019
41
1.180
Why?
High-Throughput Nucleotide Sequencing
9
2020
486
0.980
Why?
Repressor Proteins
2
2019
404
0.940
Why?
Unfolded Protein Response
4
2019
53
0.900
Why?
Sequence Analysis, DNA
5
2020
778
0.880
Why?
RNA Stability
4
2019
103
0.830
Why?
Introns
5
2017
249
0.730
Why?
RNA Ligase (ATP)
3
2017
5
0.710
Why?
Gene Expression Regulation, Fungal
3
2019
68
0.700
Why?
Endoribonucleases
3
2015
72
0.680
Why?
Phosphorylation
1
2023
1716
0.590
Why?
RNA Cleavage
2
2015
10
0.590
Why?
DNA
3
2021
1406
0.570
Why?
Phosphotransferases (Alcohol Group Acceptor)
1
2017
42
0.570
Why?
Protein Interaction Mapping
3
2010
107
0.560
Why?
Cell Cycle Proteins
2
2017
583
0.540
Why?
RNA Precursors
4
2014
148
0.520
Why?
Gene Expression
3
2020
1465
0.510
Why?
Transcriptome
4
2022
875
0.490
Why?
Base Sequence
11
2015
2142
0.480
Why?
RNA Nucleotidyltransferases
2
2014
20
0.470
Why?
Pyrimidine Dimers
1
2014
6
0.460
Why?
DNA Repair Enzymes
1
2014
20
0.450
Why?
RNA, Catalytic
5
2004
185
0.440
Why?
MicroRNAs
4
2016
680
0.370
Why?
Alternative Splicing
1
2013
216
0.360
Why?
RNA, Long Noncoding
1
2013
177
0.350
Why?
Lymph Nodes
3
2024
471
0.350
Why?
Saccharomyces
1
2010
8
0.340
Why?
Chimera
1
2010
57
0.340
Why?
Molecular Sequence Data
12
2015
2833
0.330
Why?
RNA, Transfer
2
2023
130
0.320
Why?
DNA Footprinting
1
2009
33
0.310
Why?
Spliceosomes
3
2014
46
0.310
Why?
Nucleosomes
1
2010
137
0.300
Why?
Biosensing Techniques
4
2006
118
0.290
Why?
Software
4
2021
608
0.280
Why?
Binding Sites
6
2018
1251
0.280
Why?
Uracil
2
2018
31
0.280
Why?
DNA Replication
3
2017
225
0.270
Why?
Models, Genetic
4
2010
592
0.260
Why?
Oligonucleotides
3
2004
146
0.250
Why?
Computational Biology
4
2021
593
0.250
Why?
Protein Array Analysis
1
2006
56
0.250
Why?
Hibernation
2
2018
74
0.250
Why?
Ligases
2
2003
30
0.250
Why?
Polyadenylation
2
2017
40
0.250
Why?
Chikungunya Fever
2
2024
76
0.240
Why?
Promoter Regions, Genetic
1
2010
1213
0.240
Why?
Genome, Fungal
3
2017
33
0.230
Why?
Cell Differentiation
4
2023
1900
0.230
Why?
Exons
2
2017
341
0.230
Why?
Endothelial Cells
5
2024
749
0.220
Why?
Transcription Factors
3
2023
1645
0.220
Why?
Protein Binding
7
2020
2123
0.210
Why?
Mutation
7
2020
3706
0.210
Why?
RNA, Small Nuclear
3
2014
35
0.210
Why?
Gene Library
3
2019
115
0.210
Why?
Gene Expression Profiling
6
2021
1686
0.210
Why?
RNA, Viral
3
2021
620
0.210
Why?
Genetic Techniques
3
2015
62
0.210
Why?
Signal Transduction
5
2020
4935
0.210
Why?
Yeasts
2
2018
52
0.200
Why?
Chikungunya virus
1
2024
76
0.200
Why?
Escherichia coli
2
2018
766
0.190
Why?
Amino Acid Sequence
3
2014
2057
0.190
Why?
Animals
19
2024
35409
0.190
Why?
Gain of Function Mutation
1
2021
34
0.190
Why?
Haploinsufficiency
1
2021
48
0.180
Why?
Alphavirus Infections
1
2021
44
0.180
Why?
Replication Origin
2
2017
17
0.180
Why?
Immunoprecipitation
3
2016
156
0.180
Why?
Gene Editing
1
2021
68
0.180
Why?
Lymphocyte Activation
1
2025
1110
0.180
Why?
Viremia
1
2021
132
0.170
Why?
Murine hepatitis virus
1
2020
16
0.170
Why?
RNA, Small Cytoplasmic
1
2020
7
0.170
Why?
Sensitivity and Specificity
4
2016
1847
0.170
Why?
Receptors, Immunologic
1
2021
216
0.170
Why?
Ricin
1
2000
8
0.170
Why?
Viral Nonstructural Proteins
1
2020
61
0.170
Why?
Mice
10
2023
16983
0.170
Why?
Sequence Alignment
2
2014
331
0.170
Why?
rac GTP-Binding Proteins
1
2020
32
0.170
Why?
Cerebellar Neoplasms
1
2022
150
0.160
Why?
Neoplastic Cells, Circulating
1
2020
70
0.160
Why?
Cluster Analysis
2
2019
483
0.160
Why?
Mouse Embryonic Stem Cells
1
2020
30
0.160
Why?
Medulloblastoma
1
2022
191
0.160
Why?
B-Lymphocytes
1
2025
816
0.160
Why?
Extracellular Fluid
1
2019
31
0.160
Why?
Genetic Therapy
1
2021
293
0.160
Why?
Cell Line
4
2020
2780
0.160
Why?
rho GTP-Binding Proteins
1
2020
60
0.160
Why?
Integrins
1
2020
94
0.160
Why?
Antigens
1
2021
356
0.160
Why?
Myeloid-Lymphoid Leukemia Protein
1
2020
70
0.160
Why?
DNA, Single-Stranded
1
2000
114
0.150
Why?
Hematopoiesis
1
2020
184
0.150
Why?
Exoribonucleases
1
2019
43
0.150
Why?
DNA, Complementary
1
2019
266
0.150
Why?
RNA Editing
1
2018
20
0.150
Why?
Ependymoma
1
2020
161
0.150
Why?
Thymocytes
1
2018
34
0.150
Why?
Lymphocytes
1
2020
377
0.150
Why?
Histone-Lysine N-Methyltransferase
1
2020
124
0.140
Why?
Alveolar Epithelial Cells
1
2019
107
0.140
Why?
Mice, Inbred C57BL
7
2023
5468
0.140
Why?
Tunicamycin
1
2017
11
0.140
Why?
Bleomycin
1
2019
243
0.140
Why?
Chromatids
1
2017
8
0.140
Why?
Substrate Specificity
2
2017
371
0.140
Why?
Cells, Cultured
7
2021
4102
0.140
Why?
Natural Killer T-Cells
1
2018
65
0.140
Why?
Precision Medicine
1
2021
385
0.140
Why?
Meiosis
1
2017
65
0.140
Why?
Azacitidine
1
2018
137
0.140
Why?
RNA-Binding Proteins
2
2016
388
0.140
Why?
Epilepsy
1
2021
322
0.140
Why?
Regeneration
1
2019
182
0.140
Why?
CD8-Positive T-Lymphocytes
1
2023
855
0.140
Why?
Superoxide Dismutase
1
2019
342
0.140
Why?
Hepatitis C, Chronic
1
2019
156
0.140
Why?
Autoantibodies
1
2025
1468
0.140
Why?
Ligands
4
2006
621
0.140
Why?
Mutagenesis
1
2017
179
0.130
Why?
Bridged Bicyclo Compounds, Heterocyclic
1
2018
217
0.130
Why?
DNA, Mitochondrial
2
2015
190
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2007
756
0.130
Why?
Recombination, Genetic
1
2017
189
0.130
Why?
Mammals
1
2018
274
0.130
Why?
Membrane Glycoproteins
1
2019
477
0.130
Why?
Host-Pathogen Interactions
2
2021
355
0.130
Why?
Virus Integration
1
2016
69
0.130
Why?
Transforming Growth Factor beta
1
2019
462
0.130
Why?
Lung Injury
1
2019
211
0.130
Why?
Macrophages, Alveolar
1
2019
389
0.130
Why?
Macrophages
3
2021
1489
0.130
Why?
RNA, Fungal
2
2014
67
0.130
Why?
Phenotype
3
2020
3062
0.130
Why?
Leukocytes, Mononuclear
1
2019
546
0.130
Why?
T-Lymphocyte Subsets
1
2018
412
0.120
Why?
Non-alcoholic Fatty Liver Disease
1
2019
260
0.120
Why?
Nucleic Acid Conformation
3
2013
706
0.120
Why?
Carcinogenesis
1
2017
214
0.120
Why?
Gene Expression Regulation
2
2018
2545
0.120
Why?
Artifacts
1
2016
127
0.120
Why?
Extracellular Matrix
1
2019
508
0.120
Why?
DNA Damage
1
2018
383
0.120
Why?
Temperature
1
2018
635
0.120
Why?
Amino Acyl-tRNA Synthetases
1
2015
30
0.120
Why?
Mitochondrial Proteins
1
2017
247
0.120
Why?
Genomics
1
2020
716
0.120
Why?
3-Hydroxyacyl CoA Dehydrogenases
1
2015
9
0.120
Why?
Acetyl-CoA C-Acetyltransferase
1
2015
9
0.120
Why?
Ultraviolet Rays
1
2018
383
0.120
Why?
Ribonucleotides
1
2015
24
0.120
Why?
Protein Biosynthesis
3
2002
406
0.120
Why?
Lipid Metabolism, Inborn Errors
1
2015
19
0.120
Why?
Humans
25
2025
129847
0.120
Why?
Sulfonamides
1
2018
497
0.120
Why?
Cytoskeletal Proteins
1
2015
147
0.110
Why?
Thermogenesis
1
2015
44
0.110
Why?
Brain
2
2018
2677
0.110
Why?
Catalysis
2
2014
312
0.110
Why?
Adipose Tissue, Brown
1
2015
51
0.110
Why?
Neoplastic Stem Cells
1
2018
378
0.110
Why?
DNA, Viral
1
2016
347
0.110
Why?
Ribonuclease, Pancreatic
1
2014
11
0.110
Why?
Influenza A virus
1
2014
100
0.110
Why?
Receptors, Antigen, T-Cell
1
2018
707
0.110
Why?
Breast Neoplasms
2
2017
2104
0.110
Why?
RNA, Small Nucleolar
1
2013
8
0.110
Why?
Drosophila Proteins
1
2015
187
0.110
Why?
Apoptosis
2
2019
2489
0.110
Why?
Escherichia coli Proteins
1
2015
179
0.110
Why?
Drosophila melanogaster
1
2015
211
0.110
Why?
Nucleic Acids
2
2006
61
0.100
Why?
Ribonucleoprotein, U5 Small Nuclear
1
2013
11
0.100
Why?
Liver
2
2019
1839
0.100
Why?
Ribonucleoprotein, U4-U6 Small Nuclear
1
2013
11
0.100
Why?
Energy Metabolism
2
2018
875
0.100
Why?
Eukaryota
1
2013
55
0.100
Why?
Bone Marrow Cells
1
2014
302
0.100
Why?
Receptors, Cytoplasmic and Nuclear
1
2014
216
0.100
Why?
Mitochondria
2
2017
875
0.100
Why?
Caenorhabditis elegans Proteins
1
2014
194
0.100
Why?
Leukemia, Myeloid, Acute
1
2018
596
0.090
Why?
Genome, Human
1
2014
393
0.090
Why?
Nerve Tissue Proteins
1
2015
569
0.090
Why?
Evolution, Molecular
2
2018
462
0.090
Why?
Adipose Tissue
1
2015
594
0.090
Why?
Mice, Transgenic
3
2021
2135
0.090
Why?
Protein Footprinting
1
2010
11
0.090
Why?
AT Rich Sequence
1
2010
4
0.090
Why?
HIV-1
1
2016
839
0.090
Why?
DNA-Binding Proteins
1
2017
1441
0.080
Why?
Transcription, Genetic
2
2015
1416
0.080
Why?
Protein Structure, Tertiary
3
2006
844
0.080
Why?
DNA Methylation
1
2014
606
0.080
Why?
Inflammation
1
2019
2748
0.070
Why?
Diabetes Mellitus, Type 1
1
2025
3630
0.070
Why?
Nucleotide Motifs
2
2020
33
0.070
Why?
DNA Primers
2
2016
508
0.070
Why?
Amino Acids
1
2010
487
0.070
Why?
Neurons
1
2015
1509
0.070
Why?
Two-Hybrid System Techniques
1
2005
55
0.060
Why?
Plasmodium falciparum
1
2005
30
0.060
Why?
Malaria, Falciparum
1
2005
27
0.060
Why?
Amino Acid Motifs
1
2006
215
0.060
Why?
Protozoan Proteins
1
2005
75
0.060
Why?
Sciuridae
2
2018
146
0.060
Why?
Toll-Like Receptors
1
2006
179
0.060
Why?
Algorithms
2
2010
1617
0.060
Why?
Metabolomics
1
2010
652
0.060
Why?
Receptors, Antigen, B-Cell
1
2025
126
0.060
Why?
Models, Biological
2
2015
1724
0.060
Why?
Mutation, Missense
1
2006
316
0.050
Why?
Databases, Nucleic Acid
1
2004
33
0.050
Why?
Gene Expression Regulation, Neoplastic
2
2022
1327
0.050
Why?
Reverse Transcription
2
2016
18
0.050
Why?
Genetic Engineering
1
2004
87
0.050
Why?
Adaptor Proteins, Signal Transducing
1
2006
399
0.050
Why?
Thiamine Pyrophosphate
1
2002
2
0.050
Why?
Cobamides
1
2002
20
0.050
Why?
Feedback, Physiological
1
2002
76
0.050
Why?
Biological Evolution
1
2006
435
0.050
Why?
Phylogeny
1
2006
845
0.050
Why?
Listeria monocytogenes
1
2023
123
0.050
Why?
Alphavirus
1
2021
20
0.050
Why?
Kupffer Cells
1
2021
50
0.050
Why?
Immunization
1
2024
411
0.050
Why?
Phosphorothioate Oligonucleotides
1
2021
11
0.050
Why?
Caveolae
1
2021
17
0.050
Why?
Peptide Fragments
2
2021
695
0.050
Why?
Metadata
1
2021
9
0.040
Why?
Oligonucleotides, Antisense
1
2021
112
0.040
Why?
Immunologic Memory
1
2023
349
0.040
Why?
Mice, Mutant Strains
1
2021
298
0.040
Why?
Ovalbumin
1
2021
178
0.040
Why?
Hedgehog Proteins
1
2022
188
0.040
Why?
Epithelial Cells
2
2014
1063
0.040
Why?
Tissue Distribution
1
2021
316
0.040
Why?
Meta-Analysis as Topic
1
2021
170
0.040
Why?
Embryoid Bodies
1
2020
7
0.040
Why?
Endocytosis
1
2021
162
0.040
Why?
Reverse Transcriptase Polymerase Chain Reaction
2
2016
954
0.040
Why?
Colony-Forming Units Assay
1
2020
90
0.040
Why?
Antigen Presentation
1
2021
207
0.040
Why?
Molecular Conformation
1
2000
141
0.040
Why?
Protein Structure, Secondary
1
2000
342
0.040
Why?
Tricarboxylic Acids
1
2018
10
0.040
Why?
beta-Defensins
1
1998
20
0.040
Why?
Antibodies
1
2001
399
0.040
Why?
Ketoglutaric Acids
1
2018
16
0.040
Why?
Antibiotics, Antineoplastic
1
2019
123
0.040
Why?
Mesoderm
1
2020
138
0.040
Why?
Lipoproteins, LDL
1
2019
127
0.040
Why?
Electron Transport Complex II
1
2018
25
0.040
Why?
Islets of Langerhans
1
2025
791
0.040
Why?
Succinate Dehydrogenase
1
2018
46
0.040
Why?
Early Growth Response Protein 2
1
2018
10
0.040
Why?
Lymphatic Vessels
1
2019
61
0.040
Why?
Primary Cell Culture
1
2019
164
0.040
Why?
Torpor
1
2018
14
0.040
Why?
Cell Adhesion
1
2020
455
0.040
Why?
In Vitro Techniques
1
2000
1092
0.040
Why?
NFATC Transcription Factors
1
2018
86
0.040
Why?
Female
6
2025
68829
0.040
Why?
Tumor Microenvironment
1
2022
627
0.040
Why?
Loss of Function Mutation
1
2017
38
0.040
Why?
Dendritic Cells
1
2021
481
0.040
Why?
Oxidative Phosphorylation
1
2018
188
0.040
Why?
G1 Phase
1
2017
69
0.030
Why?
S Phase
1
2017
75
0.030
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
232
0.030
Why?
MCF-7 Cells
1
2017
114
0.030
Why?
Aged, 80 and over
2
2019
7066
0.030
Why?
3' Untranslated Regions
1
2017
138
0.030
Why?
Fibrosis
1
2019
526
0.030
Why?
Proteins
1
2002
944
0.030
Why?
Hematopoietic Stem Cells
1
2020
382
0.030
Why?
Male
5
2025
63759
0.030
Why?
Disease-Free Survival
1
2017
647
0.030
Why?
Lipopolysaccharides
1
2019
872
0.030
Why?
Mice, Inbred BALB C
1
2018
1248
0.030
Why?
Crosses, Genetic
1
2015
134
0.030
Why?
Uracil-DNA Glycosidase
1
2015
1
0.030
Why?
GC Rich Sequence
1
2015
4
0.030
Why?
Gas Chromatography-Mass Spectrometry
1
2015
131
0.030
Why?
Mental Retardation, X-Linked
1
2015
13
0.030
Why?
Dyskinesias
1
2015
19
0.030
Why?
DNA, Fungal
1
2015
75
0.030
Why?
Molecular Sequence Annotation
1
2015
88
0.030
Why?
Cell Respiration
1
2015
98
0.030
Why?
Body Size
1
2015
103
0.030
Why?
Electron Transport
1
2015
112
0.030
Why?
Reactive Oxygen Species
1
2017
592
0.030
Why?
Hydrolysis
1
2014
186
0.030
Why?
Larva
1
2015
215
0.030
Why?
Serrate-Jagged Proteins
1
2014
27
0.030
Why?
Jagged-1 Protein
1
2014
23
0.030
Why?
Argonaute Proteins
1
2014
27
0.030
Why?
Receptors, Steroid
1
2014
49
0.030
Why?
Wnt-5a Protein
1
2014
21
0.030
Why?
Arousal
1
2015
150
0.030
Why?
RNA Processing, Post-Transcriptional
1
2015
88
0.030
Why?
Body Temperature
1
2015
214
0.030
Why?
Matrix Metalloproteinase 2
1
2014
56
0.030
Why?
Chromatin
1
2017
478
0.030
Why?
Gene Knockdown Techniques
1
2014
317
0.030
Why?
Muscles
1
2015
320
0.030
Why?
Stromal Cells
1
2014
106
0.030
Why?
Neoplasm Grading
1
2014
283
0.030
Why?
Cellular Microenvironment
1
2014
84
0.030
Why?
Poliovirus
1
2014
82
0.030
Why?
RNA, Ribosomal
1
2014
161
0.030
Why?
Ribonucleoproteins, Small Nuclear
1
2013
22
0.030
Why?
Child
2
2025
20962
0.030
Why?
Wnt Proteins
1
2014
126
0.030
Why?
Chronic Disease
1
2019
1724
0.030
Why?
Calcium-Binding Proteins
1
2014
213
0.020
Why?
Base Pairing
2
2004
61
0.020
Why?
RNA Interference
1
2014
451
0.020
Why?
HeLa Cells
1
2014
611
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2014
373
0.020
Why?
Hepacivirus
1
2014
242
0.020
Why?
Gene Regulatory Networks
1
2014
280
0.020
Why?
Virus Replication
1
2014
453
0.020
Why?
Polymorphism, Single Nucleotide
1
2019
2062
0.020
Why?
Down-Regulation
1
2014
631
0.020
Why?
Estrogens
1
2014
348
0.020
Why?
Receptors, Estrogen
1
2014
422
0.020
Why?
Caenorhabditis elegans
1
2014
296
0.020
Why?
Vascular Endothelial Growth Factor A
1
2014
528
0.020
Why?
Carrier Proteins
1
2014
741
0.020
Why?
Gene Expression Regulation, Developmental
1
2015
820
0.020
Why?
Time Factors
1
2021
6550
0.020
Why?
Proto-Oncogene Proteins
1
2014
634
0.020
Why?
Rats
1
2019
5487
0.020
Why?
Transcription Initiation Site
1
2010
43
0.020
Why?
Adult
2
2025
35634
0.020
Why?
Aged
2
2019
22107
0.020
Why?
Brain Chemistry
1
2010
118
0.020
Why?
Myocardium
1
2015
983
0.020
Why?
Organophosphates
1
2010
122
0.020
Why?
Arabidopsis
1
2010
85
0.020
Why?
Cloning, Molecular
1
2010
524
0.020
Why?
Disease Models, Animal
1
2019
4077
0.020
Why?
Gene Deletion
1
2010
380
0.020
Why?
Biomarkers
1
2020
3971
0.020
Why?
Bayes Theorem
1
2010
374
0.020
Why?
Genome
1
2010
278
0.020
Why?
Membrane Proteins
1
2014
1119
0.020
Why?
Cell Line, Tumor
1
2014
3185
0.020
Why?
Lung
1
2019
3940
0.020
Why?
Chaperonin 60
1
2006
14
0.020
Why?
Severity of Illness Index
1
2014
2739
0.020
Why?
Adolescent
1
2025
20451
0.020
Why?
Prognosis
1
2014
3773
0.020
Why?
Aptamers, Nucleotide
1
2006
77
0.020
Why?
Myeloid Differentiation Factor 88
1
2006
97
0.010
Why?
Genetic Variation
1
2010
937
0.010
Why?
Virulence Factors
1
2005
157
0.010
Why?
Infant, Newborn
1
2015
5772
0.010
Why?
Biotinylation
1
2002
29
0.010
Why?
Ribonucleoprotein, U1 Small Nuclear
1
2002
13
0.010
Why?
Automation
1
2002
81
0.010
Why?
HIV Infections
1
2016
2730
0.010
Why?
Directed Molecular Evolution
1
2001
26
0.010
Why?
Infant
1
2015
9018
0.010
Why?
Internet
1
2004
620
0.010
Why?
Reproducibility of Results
1
2007
3089
0.010
Why?
Defensins
1
1998
4
0.010
Why?
In Situ Hybridization
1
1998
296
0.010
Why?
Middle Aged
1
2019
31177
0.010
Why?
Respiratory System
1
1998
156
0.010
Why?
Models, Molecular
1
2001
1488
0.010
Why?
Interleukin-1
1
1998
956
0.010
Why?
Hesselberth's Networks
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