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Jefferson Matthew Taliaferro

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics

    Collapse Research 
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    R01NS122911     (TALIAFERRO, JEFFERSON MATTHEW)Sep 19, 2023 - Aug 31, 2028
    NIH
    Mechanistic analysis of TDP-43-mediated RNA localization in neurons and its misregulation in ALS
    Role: Principal Investigator
    R35GM133385     (TALIAFERRO, JEFFERSON MATTHEW)Aug 15, 2019 - Jul 31, 2024
    NIH
    Understanding the regulatory language of RNA localization
    Role: Principal Investigator
    F32GM109562     (TALIAFERRO, JEFFERSON MATTHEW)Jan 1, 2014 - Dec 31, 2016
    NIH
    Genome-wide identification of mRNA localization motifs and factors
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Eiler DR, Wimberly BT, Bilodeau DY, Taliaferro JM, Reigan P, Rissland OS, Kieft JS. The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure. 2024 Apr 04; 32(4):400-410.e4. PMID: 38242118.
      View in: PubMed
    2. Espinosa S, De Bortoli F, Li X, Rossi J, Wagley ME, Lo HG, Taliaferro JM, Zhao R. Human PRPF39 is an alternative splicing factor recruiting U1 snRNP to weak 5' splice sites. RNA. 2022 Oct 31. PMID: 36316087.
      View in: PubMed
    3. Arora A, Castro-Gutierrez R, Moffatt C, Eletto D, Becker R, Brown M, Moor AE, Russ HA, Taliaferro JM. High-throughput identification of RNA localization elements in neuronal cells. Nucleic Acids Res. 2022 10 14; 50(18):10626-10642. PMID: 36107770.
      View in: PubMed
    4. Lee S, Chen YC, Gillen AE, Taliaferro JM, Deplancke B, Li H, Lai EC. Diverse cell-specific patterns of alternative polyadenylation in Drosophila. Nat Commun. 2022 09 13; 13(1):5372. PMID: 36100597.
      View in: PubMed
    5. Lo HG, Engel KL, Goering R, Li Y, Spitale RC, Taliaferro JM. Halo-seq: An RNA Proximity Labeling Method for the Isolation and Analysis of Subcellular RNA Populations. Curr Protoc. 2022 May; 2(5):e424. PMID: 35532287.
      View in: PubMed
    6. Engel KL, Lo HG, Goering R, Li Y, Spitale RC, Taliaferro JM. Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq. Nucleic Acids Res. 2022 02 28; 50(4):e24. PMID: 34875090.
      View in: PubMed
    7. Arora A, Goering R, Lo HYG, Lo J, Moffatt C, Taliaferro JM. The Role of Alternative Polyadenylation in the Regulation of Subcellular RNA Localization. Front Genet. 2021; 12:818668. PMID: 35096024.
      View in: PubMed
    8. Taliaferro JM. Transcriptome-scale methods for uncovering subcellular RNA localization mechanisms. Biochim Biophys Acta Mol Cell Res. 2022 04; 1869(4):119202. PMID: 34998919.
      View in: PubMed
    9. Arora A, Goering R, Velez PT, Taliaferro JM. Visualization and Quantification of Subcellular RNA Localization Using Single-Molecule RNA Fluorescence In Situ Hybridization. Methods Mol Biol. 2022; 2404:247-266. PMID: 34694613.
      View in: PubMed
    10. Goering R, Engel KL, Gillen AE, Fong N, Bentley DL, Taliaferro JM. LABRAT reveals association of alternative polyadenylation with transcript localization, RNA binding protein expression, transcription speed, and cancer survival. BMC Genomics. 2021 Jun 26; 22(1):476. PMID: 34174817.
      View in: PubMed
    11. Gillen AE, Goering R, Taliaferro JM. Quantifying alternative polyadenylation in RNAseq data with LABRAT. Methods Enzymol. 2021; 655:245-263. PMID: 34183124.
      View in: PubMed
    12. Hudish LI, Bubak A, Triolo TM, Niemeyer CS, Lorberbaum DS, Sussel L, Nagel M, Taliaferro JM, Russ HA. Modeling Hypoxia-Induced Neuropathies Using a Fast and Scalable Human Motor Neuron Differentiation System. Stem Cell Reports. 2021 Apr 13; 16(4):1009. PMID: 33852882.
      View in: PubMed
    13. Raj N, McEachin ZT, Harousseau W, Zhou Y, Zhang F, Merritt-Garza ME, Taliaferro JM, Kalinowska M, Marro SG, Hales CM, Berry-Kravis E, Wolf-Ochoa MW, Martinez-Cerde?o V, Wernig M, Chen L, Klann E, Warren ST, Jin P, Wen Z, Bassell GJ. Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis. Cell Rep. 2021 04 13; 35(2):108991. PMID: 33852833.
      View in: PubMed
    14. Lee S, Wei L, Zhang B, Goering R, Majumdar S, Wen J, Taliaferro JM, Lai EC. ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. PLoS Genet. 2021 04; 17(4):e1009439. PMID: 33826609.
      View in: PubMed
    15. Goering R, Hudish LI, Guzman BB, Raj N, Bassell GJ, Russ HA, Dominguez D, Taliaferro JM. FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences. Elife. 2020 06 08; 9. PMID: 32510328.
      View in: PubMed
    16. Hudish LI, Bubak A, Triolo TM, Niemeyer CS, Lorberbaum DS, Sussel L, Nagel M, Taliaferro JM, Russ HA. Modeling Hypoxia-Induced Neuropathies Using a Fast and Scalable Human Motor Neuron Differentiation System. Stem Cell Reports. 2020 06 09; 14(6):1033-1043. PMID: 32386561.
      View in: PubMed
    17. Engel KL, Arora A, Goering R, Lo HG, Taliaferro JM. Mechanisms and consequences of subcellular RNA localization across diverse cell types. Traffic. 2020 06; 21(6):404-418. PMID: 32291836.
      View in: PubMed
    18. Gillette CM, Hazegh KE, Nemkov T, Stefanoni D, D'Alessandro A, Taliaferro JM, Reis T. Gene-Diet Interactions: Dietary Rescue of Metabolic Effects in spen-Depleted Drosophila melanogaster. Genetics. 2020 04; 214(4):961-975. PMID: 32107279.
      View in: PubMed
    19. Narula A, Ellis J, Taliaferro JM, Rissland OS. Coding regions affect mRNA stability in human cells. RNA. 2019 12; 25(12):1751-1764. PMID: 31527111.
      View in: PubMed
    20. Taliaferro JM. Classical and emerging techniques to identify and quantify localized RNAs. Wiley Interdiscip Rev RNA. 2019 09; 10(5):e1542. PMID: 31044542.
      View in: PubMed
    21. Rothenberg DA, Taliaferro JM, Huber SM, Begley TJ, Dedon PC, White FM. A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth. iScience. 2018 Nov 30; 9:367-381. PMID: 30466063.
      View in: PubMed
    22. Wang ET, Taliaferro JM, Lee JA, Sudhakaran IP, Rossoll W, Gross C, Moss KR, Bassell GJ. Dysregulation of mRNA Localization and Translation in Genetic Disease. J Neurosci. 2016 11 09; 36(45):11418-11426. PMID: 27911744.
      View in: PubMed
    23. Taliaferro JM, Lambert NJ, Sudmant PH, Dominguez D, Merkin JJ, Alexis MS, Bazile C, Burge CB. RNA Sequence Context Effects Measured In?Vitro Predict In?Vivo Protein Binding and Regulation. Mol Cell. 2016 10 20; 64(2):294-306. PMID: 27720642.
      View in: PubMed
    24. Wang Q, Taliaferro JM, Klibaite U, Hilgers V, Shaevitz JW, Rio DC. The PSI-U1 snRNP interaction regulates male mating behavior in Drosophila. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):5269-74. PMID: 27114556.
      View in: PubMed
    25. Taliaferro JM, Vidaki M, Oliveira R, Olson S, Zhan L, Saxena T, Wang ET, Graveley BR, Gertler FB, Swanson MS, Burge CB. Distal Alternative Last Exons Localize mRNAs to Neural Projections. Mol Cell. 2016 Mar 17; 61(6):821-33. PMID: 26907613.
      View in: PubMed
    26. Taliaferro JM, Wang ET, Burge CB. Genomic analysis of RNA localization. RNA Biol. 2014; 11(8):1040-50. PMID: 25483039.
      View in: PubMed
    27. Taliaferro JM, Marwha D, Aspden JL, Mavrici D, Cheng NE, Kohlstaedt LA, Rio DC. The Drosophila splicing factor PSI is phosphorylated by casein kinase II and tousled-like kinase. PLoS One. 2013; 8(2):e56401. PMID: 23437125.
      View in: PubMed
    28. Taliaferro JM, Aspden JL, Bradley T, Marwha D, Blanchette M, Rio DC. Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression. Genes Dev. 2013 Feb 15; 27(4):378-89. PMID: 23392611.
      View in: PubMed
    29. Stolfi A, Wagner E, Taliaferro JM, Chou S, Levine M. Neural tube patterning by Ephrin, FGF and Notch signaling relays. Development. 2011 Dec; 138(24):5429-39. PMID: 22110057.
      View in: PubMed
    30. Taliaferro JM, Alvarez N, Green RE, Blanchette M, Rio DC. Evolution of a tissue-specific splicing network. Genes Dev. 2011 Mar 15; 25(6):608-20. PMID: 21406555.
      View in: PubMed
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