Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Todd Pitts

Concepts (373)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
22
2022
615
2.910
Why?
Protein Kinase Inhibitors
19
2020
785
1.980
Why?
Xenograft Model Antitumor Assays
37
2022
698
1.960
Why?
Antineoplastic Agents
25
2020
1879
1.550
Why?
Azepines
4
2020
75
1.400
Why?
Pyrimidines
9
2020
376
1.260
Why?
Pyrazines
6
2018
71
1.080
Why?
Cell Line, Tumor
33
2022
2710
1.030
Why?
Mice, Nude
24
2020
630
1.000
Why?
Cell Proliferation
21
2020
2186
0.880
Why?
Fluorouracil
1
2022
152
0.780
Why?
Triple Negative Breast Neoplasms
6
2020
157
0.770
Why?
Apoptosis
20
2022
2362
0.660
Why?
Camptothecin
5
2022
96
0.650
Why?
Imidazoles
4
2018
208
0.650
Why?
Proto-Oncogene Proteins
5
2018
608
0.650
Why?
Aurora Kinase A
4
2020
51
0.650
Why?
Drug Resistance, Neoplasm
11
2020
636
0.600
Why?
Drug Synergism
4
2014
316
0.580
Why?
Neoplasms
9
2022
2097
0.570
Why?
Cell Cycle Proteins
2
2018
551
0.520
Why?
Cell Cycle Checkpoints
3
2019
84
0.510
Why?
Hydroxamic Acids
3
2011
80
0.500
Why?
Antineoplastic Combined Chemotherapy Protocols
9
2020
1355
0.500
Why?
Tumor Microenvironment
5
2022
430
0.490
Why?
Mice
38
2022
14860
0.490
Why?
Histone Deacetylase Inhibitors
4
2022
198
0.490
Why?
Receptor, IGF Type 1
3
2013
58
0.480
Why?
Pyrazoles
5
2018
362
0.480
Why?
Disease Models, Animal
10
2022
3531
0.470
Why?
Adrenocortical Carcinoma
3
2020
47
0.460
Why?
Mitogen-Activated Protein Kinases
3
2014
278
0.450
Why?
Antimitotic Agents
1
2013
8
0.450
Why?
Benzimidazoles
5
2018
138
0.440
Why?
Pancreatic Neoplasms
5
2020
731
0.430
Why?
TOR Serine-Threonine Kinases
2
2018
358
0.420
Why?
G2 Phase Cell Cycle Checkpoints
4
2022
41
0.420
Why?
Cyclin-Dependent Kinases
1
2013
111
0.420
Why?
Animals
42
2022
31694
0.420
Why?
Boronic Acids
2
2011
33
0.410
Why?
Molecular Targeted Therapy
2
2019
347
0.400
Why?
Quinoxalines
4
2020
60
0.390
Why?
Colonic Neoplasms
2
2013
215
0.370
Why?
Biomarkers, Tumor
6
2018
1040
0.370
Why?
Melanoma
4
2018
619
0.360
Why?
Signal Transduction
17
2019
4509
0.350
Why?
Drug Screening Assays, Antitumor
5
2020
180
0.350
Why?
Heterografts
3
2021
117
0.350
Why?
Oxidoreductases Acting on CH-CH Group Donors
2
2020
20
0.330
Why?
Gene Expression Regulation, Neoplastic
9
2020
1141
0.320
Why?
Wnt Signaling Pathway
4
2020
146
0.310
Why?
Gene Expression Profiling
6
2016
1518
0.310
Why?
Adrenal Cortex Neoplasms
2
2020
48
0.310
Why?
Cell Cycle
7
2018
542
0.300
Why?
Ephrin-B2
2
2019
36
0.300
Why?
Enzyme Inhibitors
5
2020
750
0.300
Why?
Piperazines
2
2020
309
0.290
Why?
Humans
60
2022
114623
0.290
Why?
Programmed Cell Death 1 Receptor
2
2020
193
0.290
Why?
Deoxycytidine
2
2020
138
0.290
Why?
Drug Delivery Systems
1
2010
296
0.290
Why?
Tumor Suppressor Protein p53
4
2016
445
0.280
Why?
Quinazolines
3
2015
240
0.280
Why?
Phosphatidylinositol 3-Kinases
5
2018
329
0.270
Why?
Anilides
2
2018
67
0.270
Why?
Oncogene Proteins, Fusion
2
2018
179
0.260
Why?
Mitogen-Activated Protein Kinase Kinases
3
2019
113
0.260
Why?
Mutation
9
2018
3344
0.260
Why?
Female
38
2020
59466
0.260
Why?
Gene Dosage
4
2015
129
0.250
Why?
Cyclosporine
2
2018
161
0.250
Why?
Lymphocytes, Tumor-Infiltrating
3
2020
111
0.250
Why?
Immunoblotting
6
2015
283
0.240
Why?
Pyrimidinones
2
2015
88
0.240
Why?
Proto-Oncogene Proteins B-raf
3
2018
192
0.240
Why?
Proto-Oncogene Proteins p21(ras)
6
2016
228
0.230
Why?
Pyridones
2
2015
123
0.230
Why?
ras Proteins
4
2013
138
0.230
Why?
Receptor, Notch1
2
2015
59
0.220
Why?
Neoplasm Transplantation
4
2018
228
0.220
Why?
Pyridines
2
2018
425
0.210
Why?
Immunotherapy
3
2022
474
0.210
Why?
Antineoplastic Agents, Immunological
3
2020
152
0.210
Why?
HCT116 Cells
3
2018
70
0.210
Why?
Ataxia Telangiectasia Mutated Proteins
1
2022
63
0.210
Why?
Drug Design
2
2013
148
0.200
Why?
beta Catenin
2
2020
219
0.190
Why?
Gene Knockdown Techniques
4
2020
299
0.180
Why?
DNA-Binding Proteins
2
2020
1314
0.180
Why?
Momordica charantia
1
2020
13
0.180
Why?
Benzoxazoles
1
2020
16
0.180
Why?
HT29 Cells
2
2018
35
0.170
Why?
Neoplasms, Experimental
2
2019
151
0.170
Why?
Immune System
1
2021
172
0.170
Why?
eIF-2 Kinase
1
2019
24
0.170
Why?
src-Family Kinases
2
2017
88
0.160
Why?
Receptor, EphB4
1
2019
23
0.160
Why?
DNA Helicases
1
2020
133
0.160
Why?
Tumor Burden
2
2018
259
0.160
Why?
Inhibitory Concentration 50
2
2016
74
0.160
Why?
Plant Extracts
1
2020
154
0.160
Why?
Breast Neoplasms, Male
1
2018
28
0.150
Why?
Coenzymes
1
2018
16
0.150
Why?
4-Aminobenzoic Acid
1
2018
6
0.150
Why?
Thermodynamics
1
2020
382
0.150
Why?
Neoplasm Invasiveness
3
2020
442
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
68
0.150
Why?
Septins
1
2018
40
0.150
Why?
Adrenal Cortex
1
2018
32
0.150
Why?
Oncogene Proteins v-abl
1
2017
4
0.150
Why?
Carcinoma, Pancreatic Ductal
1
2020
211
0.150
Why?
Dasatinib
1
2017
46
0.150
Why?
Colorectal Neoplasms, Hereditary Nonpolyposis
1
2018
30
0.140
Why?
Neoplasm Proteins
1
2020
384
0.140
Why?
Angiogenesis Inhibitors
3
2018
214
0.140
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2014
86
0.140
Why?
Ubiquitin-Activating Enzymes
1
2016
13
0.140
Why?
Cyclopentanes
1
2016
15
0.140
Why?
Tumor Cells, Cultured
4
2020
849
0.140
Why?
Corynebacterium
1
2017
35
0.140
Why?
Transplantation, Heterologous
4
2022
181
0.140
Why?
Corynebacterium Infections
1
2017
31
0.130
Why?
Insulin-Like Growth Factor I
1
2018
286
0.130
Why?
Tankyrases
1
2016
12
0.130
Why?
Autophagy
1
2018
233
0.130
Why?
Cetuximab
1
2016
90
0.130
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
107
0.130
Why?
Biliary Tract Neoplasms
1
2015
20
0.130
Why?
Capecitabine
1
2015
45
0.130
Why?
Adenocarcinoma
2
2020
795
0.130
Why?
Amyloid Precursor Protein Secretases
2
2013
72
0.130
Why?
Drug Discovery
1
2016
123
0.130
Why?
Antibodies, Monoclonal, Humanized
1
2020
663
0.120
Why?
Genes, ras
2
2018
91
0.120
Why?
Cell Survival
3
2019
1020
0.120
Why?
Diphenylamine
1
2014
6
0.120
Why?
Germ-Line Mutation
2
2018
130
0.120
Why?
DNA Copy Number Variations
1
2015
154
0.120
Why?
Piperidines
1
2015
160
0.120
Why?
Proto-Oncogene Proteins c-met
1
2014
67
0.110
Why?
Benzamides
1
2014
169
0.110
Why?
Urinary Bladder Neoplasms
1
2016
196
0.110
Why?
Protein Kinases
1
2015
307
0.110
Why?
Up-Regulation
1
2016
807
0.110
Why?
Receptor, Insulin
1
2013
93
0.110
Why?
Tetrahydronaphthalenes
1
2013
31
0.110
Why?
Valine
1
2013
72
0.110
Why?
Tumor Suppressor Proteins
1
2015
282
0.100
Why?
Mitosis
1
2013
164
0.100
Why?
Receptors, Notch
1
2013
84
0.100
Why?
Bortezomib
2
2011
41
0.100
Why?
Head and Neck Neoplasms
1
2016
427
0.100
Why?
Middle Aged
12
2020
26719
0.100
Why?
Computational Biology
1
2015
530
0.100
Why?
Sirolimus
1
2013
181
0.100
Why?
Antineoplastic Agents, Phytogenic
1
2013
181
0.100
Why?
3' Untranslated Regions
1
2012
129
0.100
Why?
Carcinoma, Squamous Cell
1
2016
577
0.100
Why?
Benzodioxoles
1
2012
83
0.090
Why?
Aldehyde Dehydrogenase
1
2012
102
0.090
Why?
Proteasome Inhibitors
1
2011
40
0.090
Why?
Nuclear Proteins
1
2015
591
0.090
Why?
Neoplasm Metastasis
3
2018
522
0.090
Why?
Protease Inhibitors
1
2011
97
0.090
Why?
Phosphorylation
4
2019
1569
0.090
Why?
Mice, Inbred NOD
2
2022
555
0.090
Why?
Aged
9
2020
19061
0.090
Why?
Breast Neoplasms
2
2012
1862
0.090
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
6
0.080
Why?
Mice, Inbred BALB C
3
2020
1143
0.080
Why?
Carcinoma, Hepatocellular
1
2011
211
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
66
0.080
Why?
Gastrointestinal Neoplasms
1
2009
59
0.080
Why?
Cell Movement
2
2011
868
0.080
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
76
0.080
Why?
Immunosuppressive Agents
1
2013
646
0.080
Why?
Proto-Oncogene Proteins c-akt
3
2018
398
0.080
Why?
Positron-Emission Tomography
3
2018
259
0.080
Why?
Prognosis
4
2019
3328
0.080
Why?
Neutrophils
3
2019
1176
0.070
Why?
Feasibility Studies
1
2010
739
0.070
Why?
Farnesyltranstransferase
1
2007
21
0.070
Why?
Oligonucleotide Array Sequence Analysis
3
2015
740
0.070
Why?
Protein Conformation
2
2020
805
0.070
Why?
Adult
10
2018
30528
0.070
Why?
Reproducibility of Results
2
2010
2762
0.070
Why?
Gene Expression
2
2019
1421
0.070
Why?
Maximum Tolerated Dose
2
2020
183
0.060
Why?
Male
12
2020
55554
0.060
Why?
Quinolones
1
2007
97
0.060
Why?
Neovascularization, Pathologic
2
2018
281
0.060
Why?
Models, Molecular
2
2020
1369
0.060
Why?
Structure-Activity Relationship
2
2018
502
0.060
Why?
Magnetic Resonance Spectroscopy
2
2018
473
0.050
Why?
HMGB1 Protein
1
2003
48
0.050
Why?
Proto-Oncogene Proteins c-raf
1
2002
43
0.050
Why?
Adrenergic alpha-Agonists
1
2002
29
0.050
Why?
Adrenergic alpha-Antagonists
1
2002
29
0.050
Why?
Histones
2
2022
535
0.050
Why?
Neuroimmunomodulation
1
2002
70
0.050
Why?
Histone Deacetylase 1
1
2022
16
0.050
Why?
Aurora Kinases
2
2012
28
0.050
Why?
Genetic Predisposition to Disease
1
2010
2084
0.050
Why?
Adrenergic beta-Agonists
1
2002
126
0.050
Why?
Endotoxemia
1
2002
85
0.050
Why?
Flow Cytometry
2
2019
1083
0.050
Why?
Caspase 3
2
2013
235
0.050
Why?
Acetylation
1
2022
211
0.050
Why?
Chimerism
1
2021
28
0.050
Why?
Campylobacter jejuni
1
2000
11
0.050
Why?
Lymphoid Tissue
1
2021
62
0.050
Why?
Lymphocyte Subsets
1
2021
79
0.050
Why?
Cluster Analysis
2
2012
455
0.050
Why?
Catalase
1
2000
118
0.040
Why?
TCF Transcription Factors
1
2020
20
0.040
Why?
Adrenergic beta-Antagonists
1
2002
287
0.040
Why?
Histone Deacetylases
1
2022
195
0.040
Why?
Mice, SCID
1
2021
314
0.040
Why?
RNA, Neoplasm
1
2020
80
0.040
Why?
Antimetabolites, Antineoplastic
1
2020
81
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
55
0.040
Why?
Indolizines
1
2019
3
0.040
Why?
Forkhead Box Protein M1
1
2019
5
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
96
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
22
0.040
Why?
Organoids
1
2020
74
0.040
Why?
Small Molecule Libraries
1
2020
79
0.040
Why?
MAP Kinase Kinase 2
2
2013
27
0.040
Why?
Crystallography, X-Ray
1
2020
402
0.040
Why?
MAP Kinase Kinase 1
2
2013
66
0.040
Why?
High-Throughput Screening Assays
1
2020
123
0.040
Why?
Epithelial-Mesenchymal Transition
1
2020
167
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
Genetic Linkage
1
1999
294
0.040
Why?
Flavin-Adenine Dinucleotide
1
2018
14
0.040
Why?
NADP
1
2018
43
0.040
Why?
Multifactorial Inheritance
1
1999
122
0.040
Why?
Hemorrhage
1
2002
620
0.040
Why?
Radiotherapy
1
2019
176
0.040
Why?
Nausea
1
2018
101
0.040
Why?
Carcinogenesis
1
2019
177
0.040
Why?
Aldosterone
1
2018
42
0.040
Why?
Kaplan-Meier Estimate
1
2020
811
0.040
Why?
DNA Damage
1
2020
351
0.040
Why?
Breast
1
2018
139
0.040
Why?
Drug Therapy, Combination
1
2020
951
0.040
Why?
Area Under Curve
1
2018
274
0.040
Why?
Catalytic Domain
1
2018
196
0.040
Why?
RNA, Small Interfering
1
2019
535
0.040
Why?
Diarrhea
1
2018
171
0.040
Why?
Autistic Disorder
1
1999
162
0.040
Why?
Hypertension
2
2018
1056
0.030
Why?
Recombinant Proteins
1
2020
1230
0.030
Why?
RNA, Messenger
2
2020
2552
0.030
Why?
Disease-Free Survival
1
2018
620
0.030
Why?
Fatigue
1
2018
294
0.030
Why?
Ubiquitination
1
2016
86
0.030
Why?
Axin Protein
1
2016
17
0.030
Why?
Protein Isoforms
1
2017
338
0.030
Why?
T-Lymphocytes, Regulatory
1
2019
339
0.030
Why?
Algorithms
2
2015
1466
0.030
Why?
Sequence Analysis, RNA
1
2018
385
0.030
Why?
Administration, Oral
1
2018
728
0.030
Why?
Hematopoietic Stem Cell Transplantation
1
2021
520
0.030
Why?
Jagged-1 Protein
1
2015
22
0.030
Why?
Serrate-Jagged Proteins
1
2015
27
0.030
Why?
Tumor Protein p73
1
2015
14
0.030
Why?
Gene Duplication
1
2015
62
0.030
Why?
Binding Sites
1
2018
1168
0.030
Why?
Mice, Knockout
1
2021
2565
0.030
Why?
Immunohistochemistry
1
2019
1629
0.030
Why?
Biopsy
1
2018
1036
0.030
Why?
Treatment Outcome
3
2015
9084
0.030
Why?
Databases, Genetic
1
2015
206
0.030
Why?
Transcription, Genetic
1
2020
1313
0.030
Why?
Calcium-Binding Proteins
1
2015
206
0.030
Why?
CD8-Positive T-Lymphocytes
1
2019
687
0.030
Why?
Caspase 7
1
2013
20
0.030
Why?
Butadienes
1
2013
30
0.030
Why?
Intercellular Signaling Peptides and Proteins
1
2015
351
0.030
Why?
Cell Growth Processes
1
2013
51
0.030
Why?
Survival Analysis
1
2016
1211
0.030
Why?
Phenotype
1
2021
2796
0.030
Why?
Tumor Stem Cell Assay
1
2012
33
0.030
Why?
Everolimus
1
2013
61
0.030
Why?
Nitriles
1
2013
149
0.030
Why?
Random Allocation
1
2013
335
0.030
Why?
Neoplasm Staging
1
2015
1167
0.030
Why?
Immunoprecipitation
1
2012
151
0.020
Why?
p38 Mitogen-Activated Protein Kinases
2
2003
260
0.020
Why?
Disease Progression
1
2018
2380
0.020
Why?
Calcium Signaling
1
2013
213
0.020
Why?
Cellular Senescence
1
2012
152
0.020
Why?
Kinetics
1
2014
1551
0.020
Why?
PTEN Phosphohydrolase
1
2012
140
0.020
Why?
In Situ Hybridization, Fluorescence
1
2012
309
0.020
Why?
Enzyme Activation
2
2003
785
0.020
Why?
Proteasome Endopeptidase Complex
1
2011
133
0.020
Why?
Receptor, ErbB-2
1
2012
300
0.020
Why?
Li-Fraumeni Syndrome
1
2010
11
0.020
Why?
Transcriptome
1
2015
725
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
238
0.020
Why?
Neutropenia
1
2010
125
0.020
Why?
Molecular Epidemiology
1
2010
62
0.020
Why?
Metabolome
1
2013
282
0.020
Why?
Population Groups
1
2010
57
0.020
Why?
Ligands
1
2011
561
0.020
Why?
Ki-67 Antigen
1
2010
103
0.020
Why?
Capillary Permeability
1
2010
135
0.020
Why?
Drug Combinations
1
2010
287
0.020
Why?
Australia
1
2010
206
0.020
Why?
Membrane Proteins
1
2015
1018
0.020
Why?
Keratinocytes
1
2010
216
0.020
Why?
Antibodies, Monoclonal
1
2015
1262
0.020
Why?
NF-kappa B
2
2003
638
0.020
Why?
Biomarkers
1
2019
3408
0.020
Why?
Sulfonamides
1
2011
445
0.020
Why?
Calcium
1
2013
1104
0.020
Why?
Magnetic Resonance Imaging
1
2018
3039
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
923
0.020
Why?
Enzyme-Linked Immunosorbent Assay
1
2009
797
0.020
Why?
Leukemia-Lymphoma, Adult T-Cell
1
2007
13
0.020
Why?
Verapamil
1
2007
32
0.020
Why?
Liver Neoplasms
1
2011
506
0.020
Why?
Blotting, Western
1
2009
1147
0.020
Why?
Clone Cells
1
2007
247
0.020
Why?
Dose-Response Relationship, Drug
1
2010
1842
0.020
Why?
Calcium Channel Blockers
1
2007
114
0.020
Why?
Metabolomics
1
2011
521
0.020
Why?
Family
1
2010
589
0.020
Why?
Cohort Studies
1
2015
4894
0.020
Why?
MicroRNAs
1
2012
600
0.020
Why?
Ovarian Neoplasms
1
2010
388
0.020
Why?
Adolescent
2
2018
17831
0.010
Why?
Phosphotransferases
1
2003
25
0.010
Why?
Young Adult
1
2018
10455
0.010
Why?
Phentolamine
1
2002
14
0.010
Why?
Ribosomal Protein S6 Kinases
1
2002
21
0.010
Why?
Brimonidine Tartrate
1
2002
9
0.010
Why?
Phenylephrine
1
2002
71
0.010
Why?
Propranolol
1
2002
49
0.010
Why?
Peroxidase
1
2002
163
0.010
Why?
Biological Transport
1
2003
373
0.010
Why?
Mitogen-Activated Protein Kinase 3
1
2002
146
0.010
Why?
Chemokines
1
2003
216
0.010
Why?
Cyclic AMP Response Element-Binding Protein
1
2002
127
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
130
0.010
Why?
omega-N-Methylarginine
1
2000
26
0.010
Why?
Respiratory Burst
1
2000
28
0.010
Why?
MAP Kinase Signaling System
1
2002
276
0.010
Why?
Protein Processing, Post-Translational
1
2002
399
0.010
Why?
Inflammation Mediators
1
2003
477
0.010
Why?
Lipopolysaccharides
1
2003
821
0.010
Why?
Statistical Distributions
1
1999
7
0.010
Why?
Matched-Pair Analysis
1
1999
33
0.010
Why?
Cloning, Molecular
1
2000
522
0.010
Why?
Intelligence Tests
1
1999
58
0.010
Why?
Chromosomes, Human
1
1999
39
0.010
Why?
Nuclear Family
1
1999
49
0.010
Why?
Protein-Tyrosine Kinases
1
2002
395
0.010
Why?
Hydrogen Peroxide
1
2000
288
0.010
Why?
Microsatellite Repeats
1
1999
136
0.010
Why?
Linkage Disequilibrium
1
1999
245
0.010
Why?
Models, Genetic
1
1999
562
0.010
Why?
Cells, Cultured
1
2003
3881
0.010
Why?
Cytokines
1
2003
1840
0.010
Why?
Cell Line
1
2000
2635
0.010
Why?
Molecular Sequence Data
1
1999
2785
0.010
Why?
Genotype
1
1999
1760
0.010
Why?
Sex Factors
1
1999
1715
0.010
Why?
Macrophages
1
2000
1261
0.010
Why?
Child, Preschool
1
1999
9108
0.000
Why?
Child
1
1999
18404
0.000
Why?
Pitts's Networks
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