 Antimitotic Agents
"Antimitotic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that arrest cells in MITOSIS, most notably TUBULIN MODULATORS.
| Descriptor ID |
D050256
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| MeSH Number(s) |
D27.505.519.593.249 D27.505.954.248.147
|
| Concept/Terms |
Antimitotic Agents- Antimitotic Agents
- Agents, Antimitotic
- Antimitotic Drugs
- Drugs, Antimitotic
- Antimitotics
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Below are MeSH descriptors whose meaning is more general than "Antimitotic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antimitotic Agents".
This graph shows the total number of publications written about "Antimitotic Agents" by people in this website by year, and whether "Antimitotic Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2008 | 2 | 1 | 3 | | 2009 | 2 | 0 | 2 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Antimitotic Agents" by people in Profiles.
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Kenchappa RS, Dovas A, Argenziano MG, Meyer CT, Stopfer LE, Banu MA, Pereira B, Griffith J, Mohammad A, Talele S, Haddock A, Zarco N, Elmquist W, White F, Quaranta V, Sims P, Canoll P, Rosenfeld SS. Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma. Cell Rep. 2022 06 21; 39(12):110991.
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Pitts TM, Davis SL, Eckhardt SG, Bradshaw-Pierce EL. Targeting nuclear kinases in cancer: development of cell cycle kinase inhibitors. Pharmacol Ther. 2014 May; 142(2):258-69.
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Orth JD, Loewer A, Lahav G, Mitchison TJ. Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction. Mol Biol Cell. 2012 Feb; 23(4):567-76.
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Mai CK, Sammons MF, Sammakia T. A concise formal synthesis of diazonamide A by the stereoselective construction of the C10 quaternary center. Angew Chem Int Ed Engl. 2010 Mar 22; 49(13):2397-400.
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Camidge DR. Mitotic inhibitors. J Thorac Oncol. 2009 Nov; 4(11 Suppl 3):S1074-6.
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Huang HC, Shi J, Orth JD, Mitchison TJ. Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell. 2009 Oct 06; 16(4):347-58.
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Orth JD, Tang Y, Shi J, Loy CT, Amendt C, Wilm C, Zenke FT, Mitchison TJ. Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Mol Cancer Ther. 2008 Nov; 7(11):3480-9.
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Deep G, Agarwal R. New combination therapies with cell-cycle agents. Curr Opin Investig Drugs. 2008 Jun; 9(6):591-604.
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Shi J, Orth JD, Mitchison T. Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res. 2008 May 01; 68(9):3269-76.
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Rudek MA, Zhao M, He P, Messersmith WA, Baker SD. Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ABT-751, ABT-751 glucuronide, and ABT-751 sulfate in human plasma for clinical pharmacology studies. J Pharm Biomed Anal. 2006 Sep 18; 42(2):253-60.
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