Extracellular Vesicles
"Extracellular Vesicles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane limited structures derived from cell membranes and cytoplasmic material, and released into EXTRACELLULAR SPACE. They circulate through the EXTRACELLULAR FLUID and through the peripheral blood in the MICROVASCULATURE where cells, much larger, cannot, thereby affecting a variety of intercellular communication processes.
| Descriptor ID |
D000067128
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| MeSH Number(s) |
A11.284.295.588
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| Concept/Terms |
Extracellular Vesicles- Extracellular Vesicles
- Extracellular Vesicle
- Vesicle, Extracellular
- Vesicles, Extracellular
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Below are MeSH descriptors whose meaning is more general than "Extracellular Vesicles".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Vesicles".
This graph shows the total number of publications written about "Extracellular Vesicles" by people in this website by year, and whether "Extracellular Vesicles" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 4 | 0 | 4 | | 2016 | 3 | 0 | 3 | | 2018 | 3 | 2 | 5 | | 2019 | 6 | 0 | 6 | | 2020 | 4 | 1 | 5 | | 2021 | 12 | 1 | 13 | | 2022 | 10 | 0 | 10 | | 2023 | 2 | 0 | 2 | | 2024 | 11 | 2 | 13 | | 2025 | 8 | 0 | 8 |
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Below are the most recent publications written about "Extracellular Vesicles" by people in Profiles.
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DeSouza CS, Stockelman KA, Hijmans JG, Bammert TD, Lincenburg GM, Greiner JJ, Garcia VP, Stauffer BL, DeSouza CA. Circulating endothelial extracellular vesicles progressively increase with age and are associated with endothelial vasodilator dysfunction. Am J Physiol Regul Integr Comp Physiol. 2025 Oct 01; 329(4):R509-R514.
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Eckhardt CM, Li W, Bloomquist TR, Jackson G, Joglekar N, Liu Z, De Hoff P, Vokonas PS, Sparrow D, Laurent LC, Best LG, Cole S, Umans JG, Zhang Y, Domingo-Relloso A, Sanchez TR, Schwartz J, Cheng K, Navas-Acien A, Baccarelli AA, Wu H. Extracellular vesicle-encapsulated microRNA signatures of cigarette smoking and smoking-related harm. Respir Med. 2025 Sep; 246:108226.
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Deng X, Di Germanio C, Marques de Menezes EG, Milani P, Stone M, Tanner H, Bakkour SC, Chafets DM, Reese SE, Roubinian NH, Kleinman S, Kanias T, Busch MP, Earley EJ, Page GP, Nemkov T, D'Alessandro A, Norris PJ. Donor genetics and storage conditions influence mitochondrial DNA and extracellular vesicle levels in RBC units. JCI Insight. 2025 Jul 22; 10(14).
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Silva TF, Hutchins E, Zhao W, Ciani Y, Kim M, Ko E, Mariscal J, Qiu Z, Bedier F, Kittel A, Zhou B, Wang Y, Hall M, Galasso F, Reiman R, Freeman MR, Parker S, Van Eyk J, Yang W, Posadas E, Guarnerio J, Nolan J, Théry C, Zijlstra A, Stott S, You S, Demichelis F, Boutros PC, Van Keuren-Jensen K, Di Vizio D. Extracellular vesicle heterogeneity through the lens of multiomics. Cell Rep Med. 2025 Jul 15; 6(7):102161.
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Wu CH, Yuen KL, Molony RD, Silvers CR, Akash MMH, Messing EM, Lee YF. Protein disulfide isomerase-enriched extracellular vesicles from bladder cancer cells support tumor survival and malignant transformation in the bladder. Oncogene. 2025 Jul; 44(26):2158-2169.
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Yu Z, Swift KA, Hedges MA, Theiss AL, Andres SF. Microscopic messengers: Extracellular vesicles shaping gastrointestinal health and disease. Physiol Rep. 2025 Apr; 13(7):e70292.
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Haque PS, Goodman D, Kuusivuori-Robinson T, Coughlan C, Delgado-Deida Y, Onyiah JC, Zempleni J, Theiss AL. Obese Adipose Tissue Extracellular Vesicles Activate Mitochondrial Fatty Acid ß-oxidation to Drive Colonic Stemness. Cell Mol Gastroenterol Hepatol. 2025; 19(7):101504.
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Carberry CK, Hartwell H, Rider CV, Wheeler MW, Auerbach SS, Rager JE. Extracellular Vesicle (EV) Mechanisms of Toxicity for Per and Polyfluoroalkyl Substances: Comparing Transcriptomic Points of Departure Across Global Versus EV Regulatory Gene Sets. Environ Mol Mutagen. 2025 Mar; 66(3):99-121.
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Nguyen KN, Graner AN, Fringuello AR, Zizzo Z, Valenzuela L, Anyanwu K, Lillehei KO, Youssef AS, Guzman S, Coughlan C, Graner MW. Extracellular Vesicles from a Novel Chordoma Cell Line, ARF-8, Promote Tumorigenic Microenvironmental Changes When Incubated with the Parental Cells and with Human Osteoblasts. Int J Mol Sci. 2024 Nov 27; 25(23).
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Gaylord A, Holzhausen EA, Chalifour B, Patterson WB, Tung PW, Baccarelli AA, Goran MI, Alderete TL, Kupsco A. tRNA-derived RNAs in human milk extracellular vesicles and associations with breastfeeding variables and maternal diet. Epigenomics. 2024 Dec-Dec; 16(23-24):1429-1441.
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