 Linkage Disequilibrium
"Linkage Disequilibrium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nonrandom association of linked genes. This is the tendency of the alleles of two separate but already linked loci to be found together more frequently than would be expected by chance alone.
| Descriptor ID |
D015810
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| MeSH Number(s) |
G05.348.500
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| Concept/Terms |
Linkage Disequilibrium- Linkage Disequilibrium
- Disequilibrium, Linkage
- Disequilibriums, Linkage
- Linkage Disequilibriums
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Below are MeSH descriptors whose meaning is more general than "Linkage Disequilibrium".
Below are MeSH descriptors whose meaning is more specific than "Linkage Disequilibrium".
This graph shows the total number of publications written about "Linkage Disequilibrium" by people in this website by year, and whether "Linkage Disequilibrium" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 3 | 4 | 7 | | 2002 | 1 | 4 | 5 | | 2003 | 1 | 3 | 4 | | 2004 | 3 | 5 | 8 | | 2005 | 4 | 4 | 8 | | 2006 | 1 | 6 | 7 | | 2007 | 0 | 7 | 7 | | 2008 | 0 | 10 | 10 | | 2009 | 0 | 11 | 11 | | 2010 | 1 | 9 | 10 | | 2011 | 0 | 10 | 10 | | 2012 | 0 | 9 | 9 | | 2013 | 1 | 7 | 8 | | 2014 | 0 | 7 | 7 | | 2015 | 1 | 10 | 11 | | 2016 | 1 | 10 | 11 | | 2017 | 1 | 7 | 8 | | 2018 | 2 | 6 | 8 | | 2019 | 0 | 6 | 6 | | 2020 | 0 | 6 | 6 | | 2021 | 2 | 8 | 10 | | 2022 | 0 | 3 | 3 | | 2023 | 0 | 2 | 2 | | 2024 | 2 | 1 | 3 | | 2025 | 1 | 0 | 1 | | 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Linkage Disequilibrium" by people in Profiles.
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Murphy JI, Barnard R, Null M, Hendricks AE. RAREsim2: flexible simulation of rare variant genetic data using real haplotypes. Bioinformatics. 2026 May 03; 42(5).
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Sapin E, Kelly KM, Keller MC. A novel method for across-chromosome phasing without relative data. Bioinformatics. 2026 May 03; 42(5).
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Wang H, Dombroski BA, Cheng PL, Tucci A, Si YQ, Farrell JJ, Tzeng JY, Leung YY, Malamon JS, Wang LS, Vardarajan BN, Farrer LA, Schellenberg GD, Lee WP. Structural variation detection and association analysis of whole-genome-sequence data from 16,543 Alzheimer's disease sequencing project subjects. Alzheimers Dement. 2025 06; 21(6):e70277.
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Zhang Y, Sakaue S, Morris S, Graff M, Yamamoto K, Chen Z, Li L, Keller MC, Goddard ME, Walters RG, Okada Y, Visscher PM, Yengo L. The contribution of gametic phase disequilibrium to the heritability of complex traits. Nat Genet. 2025 Jun; 57(6):1418-1425.
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Schield DR, Carter JK, Scordato ESC, Levin II, Wilkins MR, Mueller SA, Gompert Z, Nosil P, Wolf JBW, Safran RJ. Sexual selection promotes reproductive isolation in barn swallows. Science. 2024 12 13; 386(6727):eadj8766.
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Rocheleau G, Clarke SL, Auguste G, Hasbani NR, Morrison AC, Heath AS, Bielak LF, Iyer KR, Young EP, Stitziel NO, Jun G, Laurie C, Broome JG, Khan AT, Arnett DK, Becker LC, Bis JC, Boerwinkle E, Bowden DW, Carson AP, Ellinor PT, Fornage M, Franceschini N, Freedman BI, Heard-Costa NL, Hou L, Chen YI, Kenny EE, Kooperberg C, Kral BG, Loos RJF, Lutz SM, Manson JE, Martin LW, Mitchell BD, Nassir R, Palmer ND, Post WS, Preuss MH, Psaty BM, Raffield LM, Regan EA, Rich SS, Smith JA, Taylor KD, Yanek LR, Young KA, Hilliard AT, Tcheandjieu C, Peyser PA, Vasan RS, Rotter JI, Miller CL, Assimes TL, de Vries PS, Do R. Rare variant contribution to the heritability of coronary artery disease. Nat Commun. 2024 10 09; 15(1):8741.
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Armstrong ND, Patki A, Srinivasasainagendra V, Ge T, Lange LA, Kottyan L, Namjou B, Shah AS, Rasmussen-Torvik LJ, Jarvik GP, Meigs JB, Karlson EW, Limdi NA, Irvin MR, Tiwari HK. Variant level heritability estimates of type 2 diabetes in African Americans. Sci Rep. 2024 06 18; 14(1):14009.
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Anwar MY, Graff M, Highland HM, Smit R, Wang Z, Buchanan VL, Young KL, Kenny EE, Fernandez-Rhodes L, Liu S, Assimes T, Garcia DO, Daeeun K, Gignoux CR, Justice AE, Haiman CA, Buyske S, Peters U, Loos RJF, Kooperberg C, North KE. Assessing efficiency of fine-mapping obesity-associated variants through leveraging ancestry architecture and functional annotation using PAGE and UKBB cohorts. Hum Genet. 2023 Oct; 142(10):1477-1489.
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Araujo DS, Nguyen C, Hu X, Mikhaylova AV, Gignoux C, Ardlie K, Taylor KD, Durda P, Liu Y, Papanicolaou G, Cho MH, Rich SS, Rotter JI, Im HK, Manichaikul A, Wheeler HE. Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations. HGG Adv. 2023 10 12; 4(4):100216.
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Sinitambirivoutin M, Nosil P, Flaxman S, Feder J, Gompert Z, Dakos V. Early-warning signals of impending speciation. Evolution. 2023 06 01; 77(6):1444-1457.
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