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																		 Cyclic AMP Response Element-Binding Protein
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Cyclic AMP Response Element-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A protein that has been shown to function as a calcium-regulated transcription factor as well as a substrate for depolarization-activated CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. This protein functions to integrate both calcium and cAMP signals.
    
			 
				
				
					
						| Descriptor ID | D017362 |  
						| MeSH Number(s) | D12.776.260.108.184 D12.776.930.127.184 |  
						| Concept/Terms | Cyclic AMP Response Element-Binding ProteinCyclic AMP Response Element-Binding ProteinCREB ProteinDNA-Binding Protein, Cyclic AMP-ResponsiveDNA Binding Protein, Cyclic AMP ResponsivecAMP Response Element-Binding ProteincAMP Response Element Binding ProteinCyclic AMP-Responsive DNA-Binding ProteinCyclic AMP Responsive DNA Binding Protein
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				Below are MeSH descriptors whose meaning is more general than "Cyclic AMP Response Element-Binding Protein". 
				Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP Response Element-Binding Protein". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Cyclic AMP Response Element-Binding Protein" by people in this website by year, and whether "Cyclic AMP Response Element-Binding Protein" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 1 | 1 | 2 |  | 1996 | 0 | 1 | 1 |  | 1997 | 1 | 1 | 2 |  | 1998 | 1 | 0 | 1 |  | 1999 | 3 | 0 | 3 |  | 2000 | 4 | 0 | 4 |  | 2001 | 4 | 0 | 4 |  | 2002 | 2 | 3 | 5 |  | 2003 | 6 | 5 | 11 |  | 2004 | 4 | 2 | 6 |  | 2005 | 2 | 0 | 2 |  | 2006 | 4 | 3 | 7 |  | 2007 | 3 | 4 | 7 |  | 2008 | 0 | 1 | 1 |  | 2009 | 0 | 2 | 2 |  | 2010 | 3 | 1 | 4 |  | 2011 | 1 | 2 | 3 |  | 2012 | 1 | 2 | 3 |  | 2013 | 1 | 3 | 4 |  | 2014 | 0 | 1 | 1 |  | 2015 | 1 | 0 | 1 |  | 2016 | 1 | 3 | 4 |  | 2017 | 1 | 0 | 1 |  | 2018 | 1 | 1 | 2 |  | 2019 | 1 | 1 | 2 |  | 2021 | 1 | 1 | 2 |  | 2025 | 2 | 0 | 2 | 
 
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				Below are the most recent publications written about "Cyclic AMP Response Element-Binding Protein" by people in Profiles. 		
					
								
								Johnson GA, Krishnamoorthy RR, Nagaraj RH, Stankowska DL. A Neuroprotective Peptide Modulates Retinal cAMP Response Element-Binding Protein (CREB), Synapsin I (SYN1), and Growth-Associated Protein 43 (GAP43) in Rats with Silicone Oil-Induced Ocular Hypertension. Biomolecules. 2025 Feb 03; 15(2).
								Zent KH, Dell'Acqua ML. Synapse-to-Nucleus ERK?CREB Transcriptional Signaling Requires Dendrite-to-Soma Ca2+ Propagation Mediated by L-Type Voltage-Gated Ca2+ Channels. J Neurosci. 2025 Jan 22; 45(4).
								Ma J, Bruce K, Davis-Poynter N, Stevenson PG, Farrell HE. The Mouse Cytomegalovirus G Protein-Coupled Receptor Homolog, M33, Coordinates Key Features of In Vivo Infection via Distinct Components of Its Signaling Repertoire. J Virol. 2022 02 23; 96(4):e0186721.
								Cartwright IM, Dowdell AS, Lanis JM, Brink KR, Mu A, Kostelecky RE, Schaefer REM, Welch N, Onyiah JC, Hall CHT, Gerich ME, Tabor JJ, Colgan SP. Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation. Proc Natl Acad Sci U S A. 2021 05 18; 118(20).
								Laviv T, Scholl B, Parra-Bueno P, Foote B, Zhang C, Yan L, Hayano Y, Chu J, Yasuda R. In?Vivo Imaging of the Coupling between Neuronal and CREB Activity in the Mouse Brain. Neuron. 2020 03 04; 105(5):799-812.e5.
								Jung HY, Yoo DY, Nam SM, Kim JW, Kim W, Kwon HJ, Lee KY, Choi JH, Kim DW, Yoon YS, Seong JK, Hwang IK. Postnatal changes in constitutive cyclooxygenase-2 expression in the mice hippocampus and its function in synaptic plasticity. Mol Med Rep. 2019 Mar; 19(3):1996-2004.
								Jung HY, Kwon HJ, Kim W, Nam SM, Kim JW, Hahn KR, Yoo DY, Won MH, Yoon YS, Kim DW, Hwang IK. Phosphoglycerate Mutase 1 Promotes Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus by Facilitating the Phosphorylation of cAMP Response Element-Binding Protein. Neurochem Res. 2019 Feb; 44(2):323-332.
								Tonn Eisinger KR, Woolfrey KM, Swanson SP, Schnell SA, Meitzen J, Dell'Acqua M, Mermelstein PG. Palmitoylation of caveolin-1 is regulated by the same DHHC acyltransferases that modify steroid hormone receptors. J Biol Chem. 2018 10 12; 293(41):15901-15911.
								Kim YM, Gang EJ, Kahn M. CBP/Catenin antagonists: Targeting LSCs' Achilles heel. Exp Hematol. 2017 08; 52:1-11.
								Bartel S, Schulz N, Alessandrini F, Schamberger AC, Pagel P, Theis FJ, Milger K, Noessner E, Stick SM, Kicic A, Eickelberg O, Freishtat RJ, Krauss-Etschmann S. Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma. Sci Rep. 2017 04 06; 7:46026. | 
																	
																		
																			
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