Multifactorial Inheritance
"Multifactorial Inheritance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phenotypic outcome (physical characteristic or disease predisposition) that is determined by more than one gene. Polygenic refers to those determined by many genes, while oligogenic refers to those determined by a few genes.
Descriptor ID |
D020412
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MeSH Number(s) |
G05.420.590
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Concept/Terms |
Multifactorial Inheritance- Multifactorial Inheritance
- Inheritance, Multifactorial
- Inheritances, Multifactorial
- Multifactorial Inheritances
Polygenic Inheritance- Polygenic Inheritance
- Inheritance, Polygenic
- Inheritances, Polygenic
- Polygenic Inheritances
- Polygenic Traits
- Polygenic Trait
- Trait, Polygenic
- Traits, Polygenic
- Polygenic Characters
- Character, Polygenic
- Characters, Polygenic
- Polygenic Character
Oligogenic Inheritance- Oligogenic Inheritance
- Inheritance, Oligogenic
- Inheritances, Oligogenic
- Oligogenic Inheritances
- Oligogenic Traits
- Oligogenic Trait
- Trait, Oligogenic
- Traits, Oligogenic
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Below are MeSH descriptors whose meaning is more general than "Multifactorial Inheritance".
Below are MeSH descriptors whose meaning is more specific than "Multifactorial Inheritance".
This graph shows the total number of publications written about "Multifactorial Inheritance" by people in this website by year, and whether "Multifactorial Inheritance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 | 2001 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2005 | 1 | 1 | 2 | 2008 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2011 | 0 | 2 | 2 | 2012 | 1 | 0 | 1 | 2013 | 0 | 1 | 1 | 2014 | 1 | 1 | 2 | 2015 | 2 | 3 | 5 | 2016 | 2 | 1 | 3 | 2017 | 1 | 3 | 4 | 2018 | 5 | 4 | 9 | 2019 | 4 | 3 | 7 | 2020 | 2 | 4 | 6 | 2021 | 6 | 14 | 20 | 2022 | 5 | 7 | 12 | 2023 | 2 | 6 | 8 | 2024 | 4 | 9 | 13 | 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Multifactorial Inheritance" by people in Profiles.
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Kharitonova EV, Sun Q, Ockerman F, Chen B, Zhou LY, Hysong MR, Tuftin B, Cao H, Mathias RA, Auer PL, Ober C, Raffield LM, Reiner AP, Cox NJ, Kelada SNP, Tao R, Li Y. EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints-A study in asthma. Am J Hum Genet. 2025 May 01; 112(5):1199-1214.
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Santhanam N, Sanchez-Roige S, Mi S, Liang Y, Chitre AS, Munro D, Chen D, Gao J, Garcia-Martinez A, George AM, Gileta AF, Han W, Holl K, Hughson A, King CP, Lamparelli AC, Martin CD, Nyasimi F, St Pierre CL, Sumner S, Tripi J, Wang T, Chen H, Flagel S, Ishiwari K, Meyer P, Polesskaya O, Saba L, Solberg Woods LC, Palmer AA, Im HK. RatXcan: A framework for cross-species integration of genome-wide association and gene expression data. PLoS Genet. 2025 Mar; 21(3):e1011583.
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McDermott GC, Moll M, Cho MH, Hayashi K, Juge PA, Doyle TJ, Paudel ML, Kinney GL, Kronzer VL, Kim JS, O'Keeffe LA, Davis NA, Bernstein EJ, Dellaripa PF, Regan EA, Hunninghake GM, Silverman EK, Ash SY, San Jose Estepar R, Washko GR, Sparks JA. Polygenic risk scores for rheumatoid arthritis and idiopathic pulmonary fibrosis and associations with RA, interstitial lung abnormalities, and quantitative interstitial abnormalities among smokers. Semin Arthritis Rheum. 2025 Jun; 72:152708.
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Armstrong ND, Srinivasasainagendra V, Patki A, Jones AC, Parcha V, Pampana A, Broeckel U, Lange LA, Arora P, Limdi NA, Tiwari HK, Irvin MR. Utility of a Systolic Blood Pressure Polygenic Risk Score With Chlorthalidone Response. JAMA Cardiol. 2024 12 01; 9(12):1134-1141.
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Moll M, Hecker J, Platig J, Zhang J, Ghosh AJ, Pratte KA, Wang RS, Hill D, Konigsberg IR, Chiles JW, Hersh CP, Castaldi PJ, Glass K, Dy JG, Sin DD, Tal-Singer R, Mouded M, Rennard SI, Anderson GP, Kinney GL, Bowler RP, Curtis JL, McDonald ML, Silverman EK, Hobbs BD, Cho MH. Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes in the COPDGene and ECLIPSE cohort studies. EBioMedicine. 2024 Dec; 110:105429.
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Malanchini M, Allegrini AG, Nivard MG, Biroli P, Rimfeld K, Cheesman R, von Stumm S, Demange PA, van Bergen E, Grotzinger AD, Raffington L, De la Fuente J, Pingault JB, Tucker-Drob EM, Harden KP, Plomin R. Genetic associations between non-cognitive skills and academic achievement over development. Nat Hum Behav. 2024 Oct; 8(10):2034-2046.
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Gupta P, Galimberti M, Liu Y, Beck S, Wingo A, Wingo T, Adhikari K, Kranzler HR, Stein MB, Gelernter J, Levey DF. A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology. Nat Hum Behav. 2024 Nov; 8(11):2235-2249.
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Billings LK, Jablonski KA, Pan Q, Florez JC, Franks PW, Goldberg RB, Hivert MF, Kahn SE, Knowler WC, Lee CG, Merino J, Huerta-Chagoya A, Mercader JM, Raghavan S, Shi Z, Srinivasan S, Xu J, Udler MS. Increased Genetic Risk for ?-Cell Failure Is Associated With ?-Cell Function Decline in People With Prediabetes. Diabetes. 2024 Aug 01; 73(8):1352-1360.
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Kentistou KA, Kaisinger LR, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, Walters RG, Liu X, Busch AS, Helgason H, Thompson DJ, Santoni F, Petricek KM, Zouaghi Y, Huang-Doran I, Gudbjartsson DF, Bratland E, Lin K, Gardner EJ, Zhao Y, Jia RY, Terao C, Riggan MJ, Bolla MK, Yazdanpanah M, Yazdanpanah N, Bradfield JP, Broer L, Campbell A, Chasman DI, Cousminer DL, Franceschini N, Franke LH, Girotto G, He C, J?rvelin MR, Joshi PK, Kamatani Y, Karlsson R, Luan J, Lunetta KL, M?gi R, Mangino M, Medland SE, Meisinger C, Noordam R, Nutile T, Concas MP, Pola?ek O, Porcu E, Ring SM, Sala C, Smith AV, Tanaka T, van der Most PJ, Vitart V, Wang CA, Willemsen G, Zygmunt M, Ahearn TU, Andrulis IL, Anton-Culver H, Antoniou AC, Auer PL, Barnes CLK, Beckmann MW, Berrington de Gonzalez A, Bogdanova NV, Bojesen SE, Brenner H, Buring JE, Canzian F, Chang-Claude J, Couch FJ, Cox A, Crisponi L, Czene K, Daly MB, Demerath EW, Dennis J, Devilee P, De Vivo I, D?rk T, Dunning AM, Dwek M, Eriksson JG, Fasching PA, Fernandez-Rhodes L, Ferreli L, Fletcher O, Gago-Dominguez M, Garc?a-Closas M, Garc?a-S?enz JA, Gonz?lez-Neira A, Grallert H, Gu?nel P, Haiman CA, Hall P, Hamann U, Hakonarson H, Hart RJ, Hickey M, Hooning MJ, Hoppe R, Hopper JL, Hottenga JJ, Hu FB, Huebner H, Hunter DJ, Jernstr?m H, John EM, Karasik D, Khusnutdinova EK, Kristensen VN, Lacey JV, Lambrechts D, Launer LJ, Lind PA, Lindblom A, Magnusson PKE, Mannermaa A, McCarthy MI, Meitinger T, Menni C, Michailidou K, Millwood IY, Milne RL, Montgomery GW, Nevanlinna H, Nolte IM, Nyholt DR, Obi N, O'Brien KM, Offit K, Oldehinkel AJ, Ostrowski SR, Palotie A, Pedersen OB, Peters A, Pianigiani G, Plaseska-Karanfilska D, Pouta A, Pozarickij A, Radice P, Rennert G, Rosendaal FR, Ruggiero D, Saloustros E, Sandler DP, Schipf S, Schmidt CO, Schmidt MK, Small K, Spedicati B, Stampfer M, Stone J, Tamimi RM, Teras LR, Tikkanen E, Turman C, Vachon CM, Wang Q, Winqvist R, Wolk A, Zemel BS, Zheng W, van Dijk KW, Alizadeh BZ, Bandinelli S, Boerwinkle E, Boomsma DI, Ciullo M, Chenevix-Trench G, Cucca F, Esko T, Gieger C, Grant SFA, Gudnason V, Hayward C, Kolcic I, Kraft P, Lawlor DA, Martin NG, N?hr EA, Pedersen NL, Pennell CE, Ridker PM, Robino A, Snieder H, Sovio U, Spector TD, St?ckl D, Sudlow C, Timpson NJ, Toniolo D, Uitterlinden A, Ulivi S, V?lzke H, Wareham NJ, Widen E, Wilson JF, Pharoah PDP, Li L, Easton DF, Nj?lstad PR, Sulem P, Murabito JM, Murray A, Manousaki D, Juul A, Erikstrup C, Stefansson K, Horikoshi M, Chen Z, Farooqi IS, Pitteloud N, Johansson S, Day FR, Perry JRB, Ong KK. Understanding the genetic complexity of puberty timing across the allele frequency spectrum. Nat Genet. 2024 Jul; 56(7):1397-1411.
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Armstrong ND, Patki A, Srinivasasainagendra V, Ge T, Lange LA, Kottyan L, Namjou B, Shah AS, Rasmussen-Torvik LJ, Jarvik GP, Meigs JB, Karlson EW, Limdi NA, Irvin MR, Tiwari HK. Variant level heritability estimates of type 2 diabetes in African Americans. Sci Rep. 2024 06 18; 14(1):14009.
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