 Melanoma
"Melanoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Descriptor ID |
D008545
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| MeSH Number(s) |
C04.557.465.625.650.510 C04.557.580.625.650.510 C04.557.665.510
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| Concept/Terms |
Melanoma- Melanoma
- Melanomas
- Malignant Melanoma
- Malignant Melanomas
- Melanoma, Malignant
- Melanomas, Malignant
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Below are MeSH descriptors whose meaning is more general than "Melanoma".
Below are MeSH descriptors whose meaning is more specific than "Melanoma".
This graph shows the total number of publications written about "Melanoma" by people in this website by year, and whether "Melanoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 1 | 5 | | 1997 | 5 | 1 | 6 | | 1998 | 4 | 0 | 4 | | 1999 | 5 | 0 | 5 | | 2000 | 4 | 2 | 6 | | 2001 | 5 | 1 | 6 | | 2002 | 5 | 2 | 7 | | 2003 | 5 | 2 | 7 | | 2004 | 4 | 1 | 5 | | 2005 | 13 | 1 | 14 | | 2006 | 12 | 1 | 13 | | 2007 | 6 | 1 | 7 | | 2008 | 13 | 2 | 15 | | 2009 | 15 | 1 | 16 | | 2010 | 5 | 2 | 7 | | 2011 | 13 | 2 | 15 | | 2012 | 15 | 2 | 17 | | 2013 | 21 | 4 | 25 | | 2014 | 22 | 3 | 25 | | 2015 | 14 | 5 | 19 | | 2016 | 26 | 3 | 29 | | 2017 | 35 | 0 | 35 | | 2018 | 22 | 2 | 24 | | 2019 | 19 | 4 | 23 | | 2020 | 25 | 2 | 27 | | 2021 | 21 | 0 | 21 | | 2022 | 19 | 0 | 19 | | 2023 | 19 | 1 | 20 | | 2024 | 20 | 3 | 23 | | 2025 | 16 | 0 | 16 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Melanoma" by people in Profiles.
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Hwang JC, Huhmann LB, Cho K, Goryachev SD, Starink N, Weinstock MA, Asgari MM, Zheng C, Lu C, Feldman TC, Do NV, Gaziano JM, Semenov YR, Hurlbert MS, Fillmore NR, Hartman RI. Identification of Risk Factors for Acral Melanoma in US Veterans. JAMA Dermatol. 2026 03 01; 162(3):279-291.
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Lorigan P, Medina TM, Nyakas M, Rutten A, Feun LG, Cowey CL, Payne M, Hussain I, Kuzel T, O'Day S, Sheri A, Friedlander PA, Kumar S, Bergersen VS, Foss Ø, Ellingsen EB, Bjørheim J, Bechter OE. The telomerase vaccine UV1 combined with ipilimumab and nivolumab versus ipilimumab and nivolumab in advanced melanoma (INITIUM): A randomized open-label phase 2 study. Eur J Cancer. 2026 Jan 17; 233:116162.
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Geng D, Chen J, Sanchez A, Davalos SA, Wilcox P, Gonzales-Rivera D, Couts K, Tobin R, Robinson W, Nielsen AJ, Guo J, McCarter M, Crump L, Tsujimoto K, Wilky BA, Davila E. Melanoma leverages innate immune IRAK-M signaling to limit metastasis through PTPN22-Induced signaling repression. Cancer Lett. 2026 Feb 28; 639:218172.
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Wang X, Li T, Eljilany I, Soupir A, Radmacher M, Agius P, Sukrithan V, Ratan A, McCarter M, Salhia B, Colman H, Naqash AR, Puzanov I, Arnold S, Marin-Acevedo JA, Ganesan S, Churchman M, Hwu P, Rodriguez PC, Dalton WS, Weiner GJ, Tarhini AA. Multicellular immune ecotypes within solid tumors predict real-world therapeutic benefits with immune checkpoint inhibitors. Nat Commun. 2025 Nov 13; 16(1):9968.
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Morton JJ, Ramos SA, Alzofon N, Keysar SB, Armitage LH, Baker AS, Barra JM, Chimed TS, Le PN, Nieto C, Weaver AN, Thomas CM, Miller B, Robinson W, Medina TM, Gao D, Russ HA, Jimeno A. Autologous Thymic Organoids Support Functional T-cell Education and Enhance Antitumor Immunity in Humanized Mice with Melanoma Xenografts. Cancer Res Commun. 2025 Nov 01; 5(11):2053-2065.
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Neff C, Price M, Ballard CAP, Cioffi G, Liu Z, Walsh R, Barnholtz-Sloan JS, Walsh KM, Salama AKS, Anders CK, Fecci PE, Ostrom QT. Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma. Cancer Epidemiol Biomarkers Prev. 2025 Sep 02; 34(9):1600-1608.
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Nangia V, Ashraf H, Marikar N, Passanisi VJ, Ill CR, Spencer SL. MAPK and mTORC1 signaling converge to drive cyclin D1 protein production to enable cell cycle reentry in melanoma persister cells. Sci Signal. 2025 Sep 02; 18(902):eadw3231.
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Tiago M, Purwin TJ, Stefanski CD, da Silva RO, Fane ME, Chhabra Y, Haj JI, Teh JL, Kadamb R, Cai W, Rosenbaum SR, Chua V, Hacohen N, Davies MA, Villanueva J, Chervoneva I, Weeraratna AT, Erkes DA, Capparelli C, Aguirre-Ghiso JA, Aplin AE. Elevated NR2F1 underlies the persistence of invasive disease after treatment of BRAF-mutant melanoma. J Clin Invest. 2025 Sep 16; 135(18).
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Seidel JA, Alder L, Salama AKS, Anders CK, Komisarow J, Fecci PE, Sperduto P, Mullikin T, Kirkpatrick JP, Floyd SR, Reitman ZJ, Vaios EJ. Management outcomes for biopsy-proven radiation necrosis in patients with brain metastases in the era of immune-checkpoint blockade. J Neurooncol. 2025 Oct; 175(1):199-208.
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Monson KR, Ferguson R, Handzlik JE, Morales L, Xiong J, Chat V, Dagayev S, Khodadadi-Jamayran A, Simpson D, Kazlow E, Bunis A, Sreenivasaiah C, Ibrahim M, Voloshyna I, Ouwerkerk W, Luiten RM, Capone M, Madonna G, Lu Y, Shao Y, Pavlick A, Krogsgaard M, Mehnert J, Tang H, Dolfi S, Tenney D, Haanen JBAG, Gajewski TF, Hodi FS, Flaherty KT, Couts K, Robinson W, Puzanov I, Ernstoff MS, Rahma O, Postow M, Sullivan RJ, Luke JJ, Ascierto PA, Osman I, Kirchhoff T. Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma. Nat Med. 2025 Jul; 31(7):2385-2396.
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