 Epithelial-Mesenchymal Transition
"Epithelial-Mesenchymal Transition" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phenotypic changes of EPITHELIAL CELLS to MESENCHYME type, which increase cell mobility critical in many developmental processes such as NEURAL TUBE development. NEOPLASM METASTASIS and DISEASE PROGRESSION may also induce this transition.
| Descriptor ID |
D058750
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| MeSH Number(s) |
G04.356.500
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| Concept/Terms |
Epithelial-Mesenchymal Transition- Epithelial-Mesenchymal Transition
- Epithelial Mesenchymal Transition
- Epithelial-Mesenchymal Transitions
- Transition, Epithelial-Mesenchymal
- Transitions, Epithelial-Mesenchymal
- Epithelial-Mesenchymal Transformation
- Epithelial Mesenchymal Transformation
- Epithelial-Mesenchymal Transformations
- Transformation, Epithelial-Mesenchymal
- Transformations, Epithelial-Mesenchymal
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Below are MeSH descriptors whose meaning is more general than "Epithelial-Mesenchymal Transition".
Below are MeSH descriptors whose meaning is more specific than "Epithelial-Mesenchymal Transition".
This graph shows the total number of publications written about "Epithelial-Mesenchymal Transition" by people in this website by year, and whether "Epithelial-Mesenchymal Transition" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 2 | 3 | | 2011 | 5 | 7 | 12 | | 2012 | 4 | 4 | 8 | | 2013 | 2 | 4 | 6 | | 2014 | 3 | 4 | 7 | | 2015 | 2 | 3 | 5 | | 2016 | 6 | 2 | 8 | | 2017 | 2 | 4 | 6 | | 2018 | 9 | 7 | 16 | | 2019 | 2 | 4 | 6 | | 2020 | 4 | 4 | 8 | | 2021 | 2 | 1 | 3 | | 2022 | 0 | 4 | 4 | | 2023 | 0 | 2 | 2 | | 2024 | 3 | 2 | 5 | | 2025 | 0 | 6 | 6 |
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Below are the most recent publications written about "Epithelial-Mesenchymal Transition" by people in Profiles.
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Yoon EJ, Beltcheva M, Ali SS, Fu S, Yang A, Dong C, Zemke JE, Karvas RM, Chang CT, Fischer LA, Gontarz P, Zhang B, Dietmann S, Theunissen TW, Solnica-Krezel L. Manifold roles of the chemokine G-protein-coupled receptor CCR7 in differentiation of human trophoblast into extravillous and syncytiotrophoblast lineages. Development. 2025 Sep 01; 152(17).
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Kines KT, Fairchild HR, Elder AM, Cozzens LM, Strugar ZP, Wessells VM, Becks AR, Porter WW, Borges VF, Lyons TR. Aging-induced semaphorin 7a promotes TGF-ß1-mediated cell plasticity and breast tumor metastases. Cell Rep. 2025 Aug 26; 44(8):116042.
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Rosenbaum SR, Fields KM, Ford HL. Masters of adaptation: How cancer and immune cell plasticity mediates tumor progression. PLoS Biol. 2025 Jul; 23(7):e3003301.
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Sreekumar PG, Nam MH, Hong E, Kannan R, Nagaraj RH. RAGE Is Essential for Subretinal Fibrosis in Laser-Induced Choroidal Neovascularization: Therapeutic Implications. Invest Ophthalmol Vis Sci. 2025 Jun 02; 66(6):30.
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Lee GY, Schaunaman N, Nouri HR, Kraft M, Chu HW. Comprehensive single-cell RNA-sequencing study of Tollip deficiency effect in IL-13-stimulated human airway epithelial cells. BMC Res Notes. 2025 Apr 23; 18(1):194.
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Esquer H, Zhou Q, LaBarbera DV. Targeted Inhibition of CHD1L by OTI-611 Reprograms Chemotherapy and Targeted Therapy-Induced Cell Cycle Arrest and Suppresses Proliferation to Produce Synergistic Antitumor Effects in Breast and Colorectal Cancer. Cells. 2025 02 20; 14(5).
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Nguyen KN, Graner AN, Fringuello AR, Zizzo Z, Valenzuela L, Anyanwu K, Lillehei KO, Youssef AS, Guzman S, Coughlan C, Graner MW. Extracellular Vesicles from a Novel Chordoma Cell Line, ARF-8, Promote Tumorigenic Microenvironmental Changes When Incubated with the Parental Cells and with Human Osteoblasts. Int J Mol Sci. 2024 Nov 27; 25(23).
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Abdelazeem KNM, Nguyen D, Corbo S, Darragh LB, Matsumoto MW, Van Court B, Neupert B, Yu J, Olimpo NA, Osborne DG, Gadwa J, Ross RB, Nguyen A, Bhatia S, Kapoor M, Friedman RS, Jacobelli J, Saviola AJ, Knitz MW, Pasquale EB, Karam SD. Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC. Oncogene. 2025 Feb; 44(3):130-146.
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Agraval H, Kandhari K, Yadav UCS. MMPs as potential molecular targets in epithelial-to-mesenchymal transition driven COPD progression. Life Sci. 2024 Sep 01; 352:122874.
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Doke T, Bjornstad P. Endothelial-Mesenchymal Transition Switch and Diabetic Kidney Disease. J Am Soc Nephrol. 2024 Jun 01; 35(6):670-672.
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