 Immune Tolerance
"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
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| MeSH Number(s) |
G12.535.425
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 1 | 3 | | 1997 | 2 | 4 | 6 | | 1998 | 1 | 2 | 3 | | 1999 | 0 | 3 | 3 | | 2000 | 2 | 3 | 5 | | 2001 | 3 | 1 | 4 | | 2002 | 3 | 1 | 4 | | 2003 | 1 | 2 | 3 | | 2004 | 4 | 3 | 7 | | 2005 | 3 | 3 | 6 | | 2006 | 5 | 3 | 8 | | 2007 | 3 | 1 | 4 | | 2008 | 8 | 2 | 10 | | 2009 | 4 | 4 | 8 | | 2010 | 4 | 5 | 9 | | 2011 | 4 | 5 | 9 | | 2012 | 7 | 6 | 13 | | 2013 | 4 | 2 | 6 | | 2014 | 6 | 4 | 10 | | 2015 | 4 | 3 | 7 | | 2016 | 1 | 5 | 6 | | 2017 | 5 | 7 | 12 | | 2018 | 4 | 8 | 12 | | 2019 | 3 | 5 | 8 | | 2020 | 1 | 3 | 4 | | 2021 | 3 | 6 | 9 | | 2022 | 1 | 3 | 4 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 3 | 4 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Jha V, Freed BM, Sunderhaus ER, Lee JE, Prage EB, Miglani M, Rosloniec EF, Matsuda JL, Coulombe MG, McKee AS, Roark CL. Substitution of Glutamic Acid at Position 71 of DR?1*04:01 and Collagen-Specific Tolerance Without Alloreactivity. Arthritis Rheumatol. 2025 May; 77(5):526-535.
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Kremer KN, Khammash HA, Miranda AM, Rutt LN, Twardy SM, Anton PE, Campbell ML, Garza-Ortiz C, Orlicky DJ, Pelanda R, McCullough RL, Torres RM. Liver sinusoidal endothelial cells regulate the balance between hepatic immunosuppression and immunosurveillance. Front Immunol. 2024; 15:1497788.
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Blades CM, Huang CA, Mathes DW. The current state of tolerance induction in vascularized composite allotransplantation. Curr Opin Organ Transplant. 2024 Dec 01; 29(6):368-375.
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Anagnostou A, Mack DP, Johannes S, Shaker M, Abrams EM, DeSanto K, Greenhawt M. The Safety and Efficacy of Baked Egg and Milk Dietary Advancement Therapy: A Systematic Review and Meta-Analysis. J Allergy Clin Immunol Pract. 2024 Sep; 12(9):2468-2480.
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McCaleb MR, Miranda AM, Khammash HA, Torres RM, Pelanda R. Regulation of Foxo1 expression is critical for central B cell tolerance and allelic exclusion. Cell Rep. 2024 06 25; 43(6):114283.
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Smith JA, Yuen BTK, Purtha W, Balolong JM, Phipps JD, Crawford F, Bluestone JA, Kappler JW, Anderson MS. Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones. Proc Natl Acad Sci U S A. 2024 May 14; 121(20):e2320268121.
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Venter C, Vieira MC, Fleischer D. Tolerance development in non-IgE mediated food allergies: lessons from Brazil. J Pediatr (Rio J). 2024 Jan-Feb; 100(1):4-7.
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Paez-Mayorga J, Campa-Carranza JN, Capuani S, Hernandez N, Liu HC, Chua CYX, Pons-Faudoa FP, Malgir G, Alvarez B, Niles JA, Argueta LB, Shelton KA, Kezar S, Nehete PN, Berman DM, Willman MA, Li XC, Ricordi C, Nichols JE, Gaber AO, Kenyon NS, Grattoni A. Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats. Nat Commun. 2022 12 26; 13(1):7951.
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Harley ITW, Allison K, Scofield RH. Polygenic autoimmune disease risk alleles impacting B cell tolerance act in concert across shared molecular networks in mouse and in humans. Front Immunol. 2022; 13:953439.
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Williams MM, Richer JK. Revealing Molecular Mechanisms Supporting Trophoblast-Mediated Maternal Immune Tolerance. Endocrinology. 2022 08 01; 163(8).
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