 Endotoxemia
"Endotoxemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Descriptor ID |
D019446
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| MeSH Number(s) |
C01.539.757.100.275 C01.539.861.375 C23.550.470.790.500.100.275
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Endotoxemia".
Below are MeSH descriptors whose meaning is more specific than "Endotoxemia".
This graph shows the total number of publications written about "Endotoxemia" by people in this website by year, and whether "Endotoxemia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 | | 1999 | 2 | 0 | 2 | | 2000 | 4 | 0 | 4 | | 2001 | 3 | 1 | 4 | | 2002 | 4 | 1 | 5 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2007 | 1 | 2 | 3 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2012 | 2 | 0 | 2 | | 2013 | 0 | 1 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2018 | 2 | 0 | 2 | | 2019 | 3 | 0 | 3 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endotoxemia" by people in Profiles.
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Grayck MR, McCarthy WC, Solar M, Balasubramaniyan N, Zheng L, Orlicky DJ, Wright CJ. Implications of neonatal absence of innate immune mediated NF?B/AP1 signaling in the murine liver. Pediatr Res. 2024 Jun; 95(7):1791-1802.
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Shukla PK, Rao RG, Meena AS, Giorgianni F, Lee SC, Raju P, Shashikanth N, Shekhar C, Beranova S, Balazs L, Tigyi G, Gosain A, Rao R. Paneth cell dysfunction in radiation injury and radio-mitigation by human a-defensin 5. Front Immunol. 2023; 14:1174140.
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McCarthy WC, Sherlock LG, Grayck MR, Zheng L, Lacayo OA, Solar M, Orlicky DJ, Dobrinskikh E, Wright CJ. Innate Immune Zonation in the Liver: NF-?B (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific. J Immunol. 2023 05 01; 210(9):1372-1385.
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Zarate MA, De Dios RK, Balasubramaniyan D, Zheng L, Sherlock LG, Rozance PJ, Wright CJ. The Acute Hepatic NF-?B-Mediated Proinflammatory Response to Endotoxemia Is Attenuated in Intrauterine Growth-Restricted Newborn Mice. Front Immunol. 2021; 12:706774.
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Sherlock LG, Sjostrom K, Sian L, Delaney C, Tipple TE, Krebs NF, Nozik-Grayck E, Wright CJ. Hepatic-Specific Decrease in the Expression of Selenoenzymes and Factors Essential for Selenium Processing After Endotoxemia. Front Immunol. 2020; 11:595282.
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Zarate MA, Nguyen LM, De Dios RK, Zheng L, Wright CJ. Maturation of the Acute Hepatic TLR4/NF-?B Mediated Innate Immune Response Is p65 Dependent in Mice. Front Immunol. 2020; 11:1892.
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Butler B, De Dios R, Nguyen L, McKenna S, Ghosh S, Wright CJ. Developmentally Regulated Innate Immune NF?B Signaling Mediates IL-1a Expression in the Perinatal Murine Lung. Front Immunol. 2019; 10:1555.
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Davidson JA, Urban TT, Tong S, Maddux A, Hill G, Frank BS, Watson JD, Jaggers J, Sim?es EAF, Wischmeyer P. Alkaline Phosphatase Activity and Endotoxemia After Infant Cardiothoracic Surgery. Shock. 2019 03; 51(3):328-336.
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Nguyen L, Sandoval J, De Dios R, Yihdego E, Zarate M, Castro O, McKenna S, Wright CJ. The hepatic innate immune response is lobe-specific in a murine model endotoxemia. Innate Immun. 2019 02; 25(2):144-154.
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Hippensteel JA, Shapiro NI, Schmidt EP. Challenging Dogma: The Value of Bolus Fluids in the Early Resuscitation of Hyperdynamic Sepsis. Am J Respir Crit Care Med. 2018 10 15; 198(8):981-983.
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